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The map label for this gene is hldD [H]

Identifier: 16125679

GI number: 16125679

Start: 1580978

End: 1581979

Strand: Direct

Name: hldD [H]

Synonym: CC_1430

Alternate gene names: 16125679

Gene position: 1580978-1581979 (Clockwise)

Preceding gene: 16125678

Following gene: 16125680

Centisome position: 39.36

GC content: 66.87

Gene sequence:

>1002_bases
ATGAGCCGCCGCATCGTCCTGGTCACCGGCGGCGCCGGCTTCATCGGTTCGAACATCGTCGCGCGCCTCTGCGAGGATCC
GGCGCTGGATGTCGTTGTCTGCGACCGCCTGCGCGATGCGGCCAGCGGCAAGTGGCGCAACATCGCCAAGCATGCGATCG
CCGACTTCGTCGCGCCCGAGCAGCTGTTCGACTGGCTCGCTAAGCGCGGCGGTGAGGTCGAACTGGTGGTCCACATGGGC
GCGGTCTCGTCGACCACCGAGGTCGACGCGGACAAGATCGTGCAGTCCAACTTCGTCCTGTCACGCGACCTGTGGGACTG
GTGCGCCCAGCATGGCAAGCGCCTGATCTACGCCTCGTCCGCCGCCACCTATGGCGACGGCGCGCTGGGCTTTGACGGCA
AGGACGATCTGGCGTCGCTGCAGGCCCTGCGGCCGCTGAACGCCTATGGTTGGTCCAAGGCTTTGTTCGACATCTACGCC
GTGCGCGAGGCCCAGCGCGGGCGTGCGCCGGCCCAATGGGCGGGGCTGAAGTTCTTCAACGTCTACGGGCCCAATGAGGA
CCACAAGGGCGGCATGAAGTCGGTCGCGGCCCAGATCTGGCCGCGCATCGCGGCGGGCGAGGGCGTCAAGCTCTTCAAGT
CGCATCACCCGGATTACGAGGACGGCGGCCAGCTTCGCGACTTCGTTTATGTCCGCGACGTGGTCGACGTCGTCGGCTGG
CTGGCCAAGAGCCCCGCCGTGAACGGCGTCTTCAACCTCGGCTCGGGCCAGGCGCGTTCGTTCCGTGATCTGGCGGTGGC
CACGTTCGAGGCCGCGGGTCGTGCGCCCGACATCACCTATATCGACATGCCCGAGGTGCTGCGCGGCAAGTATCAGTACT
ACACCCAGGCCGACATGAGCCGCCTGCGCGCGGCCGGCTACAACGCGCCGATGACCGCGCTGGAAGACGGCGTGGCCGAC
TATGTGGCGGGCTATCTGAACACCGAAGATCCCTATCGCTGA

Upstream 100 bases:

>100_bases
ACGCGCCGTCCGACGGTCCCAACATGGTGCCGGTGAAAGAGTTCGAGGCTCTGGTCGCCAACCTGCTGCGCTACGACGCC
CTGACCAAGGCCGCCTGAGC

Downstream 100 bases:

>100_bases
ACCGCGCCCCGCTAACGTCGGGGCACGATTGCCGTCCGTTTCCGCGAGCGTAAGCTGACCGTCGATAAGTCGGGAAGAGC
CCGACGGTCAGGGAGCGAGA

Product: ADP-L-glycero-D-mannoheptose-6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSRRIVLVTGGAGFIGSNIVARLCEDPALDVVVCDRLRDAASGKWRNIAKHAIADFVAPEQLFDWLAKRGGEVELVVHMG
AVSSTTEVDADKIVQSNFVLSRDLWDWCAQHGKRLIYASSAATYGDGALGFDGKDDLASLQALRPLNAYGWSKALFDIYA
VREAQRGRAPAQWAGLKFFNVYGPNEDHKGGMKSVAAQIWPRIAAGEGVKLFKSHHPDYEDGGQLRDFVYVRDVVDVVGW
LAKSPAVNGVFNLGSGQARSFRDLAVATFEAAGRAPDITYIDMPEVLRGKYQYYTQADMSRLRAAGYNAPMTALEDGVAD
YVAGYLNTEDPYR

Sequences:

>Translated_333_residues
MSRRIVLVTGGAGFIGSNIVARLCEDPALDVVVCDRLRDAASGKWRNIAKHAIADFVAPEQLFDWLAKRGGEVELVVHMG
AVSSTTEVDADKIVQSNFVLSRDLWDWCAQHGKRLIYASSAATYGDGALGFDGKDDLASLQALRPLNAYGWSKALFDIYA
VREAQRGRAPAQWAGLKFFNVYGPNEDHKGGMKSVAAQIWPRIAAGEGVKLFKSHHPDYEDGGQLRDFVYVRDVVDVVGW
LAKSPAVNGVFNLGSGQARSFRDLAVATFEAAGRAPDITYIDMPEVLRGKYQYYTQADMSRLRAAGYNAPMTALEDGVAD
YVAGYLNTEDPYR
>Mature_332_residues
SRRIVLVTGGAGFIGSNIVARLCEDPALDVVVCDRLRDAASGKWRNIAKHAIADFVAPEQLFDWLAKRGGEVELVVHMGA
VSSTTEVDADKIVQSNFVLSRDLWDWCAQHGKRLIYASSAATYGDGALGFDGKDDLASLQALRPLNAYGWSKALFDIYAV
REAQRGRAPAQWAGLKFFNVYGPNEDHKGGMKSVAAQIWPRIAAGEGVKLFKSHHPDYEDGGQLRDFVYVRDVVDVVGWL
AKSPAVNGVFNLGSGQARSFRDLAVATFEAAGRAPDITYIDMPEVLRGKYQYYTQADMSRLRAAGYNAPMTALEDGVADY
VAGYLNTEDPYR

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=321, Percent_Identity=42.0560747663551, Blast_Score=228, Evalue=6e-61,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 36480; Mature: 36349

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRIVLVTGGAGFIGSNIVARLCEDPALDVVVCDRLRDAASGKWRNIAKHAIADFVAPE
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
QLFDWLAKRGGEVELVVHMGAVSSTTEVDADKIVQSNFVLSRDLWDWCAQHGKRLIYASS
HHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCEEEEECC
AATYGDGALGFDGKDDLASLQALRPLNAYGWSKALFDIYAVREAQRGRAPAQWAGLKFFN
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCEEEEE
VYGPNEDHKGGMKSVAAQIWPRIAAGEGVKLFKSHHPDYEDGGQLRDFVYVRDVVDVVGW
ECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LAKSPAVNGVFNLGSGQARSFRDLAVATFEAAGRAPDITYIDMPEVLRGKYQYYTQADMS
HHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHCCHHHHHHHHHHH
RLRAAGYNAPMTALEDGVADYVAGYLNTEDPYR
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SRRIVLVTGGAGFIGSNIVARLCEDPALDVVVCDRLRDAASGKWRNIAKHAIADFVAPE
CCEEEEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCHH
QLFDWLAKRGGEVELVVHMGAVSSTTEVDADKIVQSNFVLSRDLWDWCAQHGKRLIYASS
HHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCEEEEECC
AATYGDGALGFDGKDDLASLQALRPLNAYGWSKALFDIYAVREAQRGRAPAQWAGLKFFN
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCEEEEE
VYGPNEDHKGGMKSVAAQIWPRIAAGEGVKLFKSHHPDYEDGGQLRDFVYVRDVVDVVGW
ECCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
LAKSPAVNGVFNLGSGQARSFRDLAVATFEAAGRAPDITYIDMPEVLRGKYQYYTQADMS
HHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHCCHHHHHHHHHHH
RLRAAGYNAPMTALEDGVADYVAGYLNTEDPYR
HHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA