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The map label for this gene is aatC [H]

Identifier: 16125631

GI number: 16125631

Start: 1532270

End: 1533490

Strand: Direct

Name: aatC [H]

Synonym: CC_1382

Alternate gene names: 16125631

Gene position: 1532270-1533490 (Clockwise)

Preceding gene: 16125630

Following gene: 16125632

Centisome position: 38.15

GC content: 64.78

Gene sequence:

>1221_bases
ATGAGCACCGATTTCCACCGTATCCGTCGCCTCCCGCCCTACGTTTTCGAGGAGGTCAACAAGATCAAGGCCCGGCTTCG
CGCCGAGGGCACCGACATCATCGACTTCGGCATGGGCAATCCCGACATGCCGACGCCGCAGCATATCGTCGACAAGCTGA
TCGAGACCGCGCGCGATCCCAAGGCTGGGCGCTATTCCGCCTCGAAGGGCGTTCCAGGCCTTCGCAAGGCCATGGCCAAC
TATTATGGCCGCCGCTTTGGCGTGAAGCTGAACCCGGACACCGAGGTCATCGCCACGCTGGGCTCCAAGGAAGGCTTCGC
CAACCTAGCCCAGGCCCTGACGGGACCGGGCGACGTGATCATCTGCCCGAACCCGGCCTATCCGATCCACGCCTTCGGCT
TCATCATGGCCGGCGGCATCATCCGCCACGTGCCGGCGCTGTCGCCCGAGGAGTATCTGTCCAACATCAGCCGCGCGGTG
AAGCACTCGGTGCCGCCGCCCAGCGTGCTGATCCTGTCCTACCCGTCGAACCCGACGGCCCAGTGGGTCGACCTGGACTT
CTACAAGGACGCCGTGGCGCTGGCGAAGAAGCACGACCTGCTGGTCATCAGCGACGTCGCCTATGGGGAAATCTATTTCG
ACAACAATCCGCCGCCGTCGATCCTGCAGGTGGACGGGGCCAAGGACATCGCCGTCGAAGTGAACTCGCTGTCCAAGACC
TACGCCATGGCCGGCTGGCGCGTGGGCATGGTGGTCGGCAACGCCCGCATCTGCGCGGCGCTCGCCCGCGTGAAGTCTTA
TCTCGACTACGGCGCCTATACGCCGGTGCAGGTGGCCGCCGCGACGGCCCTGAACGGTCCCCAGGATTGCGTCGACGAGA
TCCGCGGCATCTACAAGAGCCGCCGCGACACGCTGATCAAGTCGATGAAGGCCGCGGGCTGGGACATCCCGAACCCGCCG
GCCTCGATGTTCGCCTGGGCCAAGATCCCTGAAGCCTATCGCGAAGCCGGCTCCATGCTGTTCTCGCGCCTGCTGATCGA
GGAGGCGGGCGTCGCCGTCGCGCCGGGCATCGGCTTTGGCGAGTACGGCGAAGGCTATGTGCGGATCGGTCTGGTCGAGA
ATGAGCACCGTATCCGCCAGGCCGCGCGCAACGTGAAGAAATTCATCGCCAACGCCGACTCCATCCTGGCCAAGGCCCAC
AACAAGATGGAACAGGCCTAA

Upstream 100 bases:

>100_bases
AGGCATAATCTTCCTTTGGCTGGCTTGGCTTGGCCCCGCTTGGGGTCTATCCATGCCCGACTTTCGCTCCCAAAGCGCCG
ACGCGGCGCATAGAGCCCTC

Downstream 100 bases:

>100_bases
GACGGCTGCGTCGGACGGCGTAACGAGGATTCGAAGATGACGAACAAGACCTGGCGCGTCGGCGTCGCGGGCCTGGGTAC
GGTTGGCGGCGGTCTCCTGC

Product: aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSTDFHRIRRLPPYVFEEVNKIKARLRAEGTDIIDFGMGNPDMPTPQHIVDKLIETARDPKAGRYSASKGVPGLRKAMAN
YYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTGPGDVIICPNPAYPIHAFGFIMAGGIIRHVPALSPEEYLSNISRAV
KHSVPPPSVLILSYPSNPTAQWVDLDFYKDAVALAKKHDLLVISDVAYGEIYFDNNPPPSILQVDGAKDIAVEVNSLSKT
YAMAGWRVGMVVGNARICAALARVKSYLDYGAYTPVQVAAATALNGPQDCVDEIRGIYKSRRDTLIKSMKAAGWDIPNPP
ASMFAWAKIPEAYREAGSMLFSRLLIEEAGVAVAPGIGFGEYGEGYVRIGLVENEHRIRQAARNVKKFIANADSILAKAH
NKMEQA

Sequences:

>Translated_406_residues
MSTDFHRIRRLPPYVFEEVNKIKARLRAEGTDIIDFGMGNPDMPTPQHIVDKLIETARDPKAGRYSASKGVPGLRKAMAN
YYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTGPGDVIICPNPAYPIHAFGFIMAGGIIRHVPALSPEEYLSNISRAV
KHSVPPPSVLILSYPSNPTAQWVDLDFYKDAVALAKKHDLLVISDVAYGEIYFDNNPPPSILQVDGAKDIAVEVNSLSKT
YAMAGWRVGMVVGNARICAALARVKSYLDYGAYTPVQVAAATALNGPQDCVDEIRGIYKSRRDTLIKSMKAAGWDIPNPP
ASMFAWAKIPEAYREAGSMLFSRLLIEEAGVAVAPGIGFGEYGEGYVRIGLVENEHRIRQAARNVKKFIANADSILAKAH
NKMEQA
>Mature_405_residues
STDFHRIRRLPPYVFEEVNKIKARLRAEGTDIIDFGMGNPDMPTPQHIVDKLIETARDPKAGRYSASKGVPGLRKAMANY
YGRRFGVKLNPDTEVIATLGSKEGFANLAQALTGPGDVIICPNPAYPIHAFGFIMAGGIIRHVPALSPEEYLSNISRAVK
HSVPPPSVLILSYPSNPTAQWVDLDFYKDAVALAKKHDLLVISDVAYGEIYFDNNPPPSILQVDGAKDIAVEVNSLSKTY
AMAGWRVGMVVGNARICAALARVKSYLDYGAYTPVQVAAATALNGPQDCVDEIRGIYKSRRDTLIKSMKAAGWDIPNPPA
SMFAWAKIPEAYREAGSMLFSRLLIEEAGVAVAPGIGFGEYGEGYVRIGLVENEHRIRQAARNVKKFIANADSILAKAHN
KMEQA

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=401, Percent_Identity=22.6932668329177, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI169881279, Length=401, Percent_Identity=22.6932668329177, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI56713256, Length=334, Percent_Identity=23.6526946107784, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI56713254, Length=334, Percent_Identity=23.6526946107784, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI1788722, Length=401, Percent_Identity=49.6259351620948, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1786816, Length=364, Percent_Identity=27.7472527472527, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI1788627, Length=280, Percent_Identity=27.5, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=404, Percent_Identity=24.5049504950495, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=24.5049504950495, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=405, Percent_Identity=21.4814814814815, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322401, Length=402, Percent_Identity=22.3880597014925, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573069, Length=389, Percent_Identity=22.6221079691517, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646114, Length=389, Percent_Identity=22.6221079691517, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28573067, Length=389, Percent_Identity=22.6221079691517, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI28573065, Length=389, Percent_Identity=22.6221079691517, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=21.4285714285714, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 44286; Mature: 44155

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTDFHRIRRLPPYVFEEVNKIKARLRAEGTDIIDFGMGNPDMPTPQHIVDKLIETARDP
CCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
KAGRYSASKGVPGLRKAMANYYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTGPGDVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHCCCCCCHHHHHHHHHCCCCCEE
ICPNPAYPIHAFGFIMAGGIIRHVPALSPEEYLSNISRAVKHSVPPPSVLILSYPSNPTA
ECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
QWVDLDFYKDAVALAKKHDLLVISDVAYGEIYFDNNPPPSILQVDGAKDIAVEVNSLSKT
EEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEEECCCCEEEEEHHHHHHH
YAMAGWRVGMVVGNARICAALARVKSYLDYGAYTPVQVAAATALNGPQDCVDEIRGIYKS
HHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDTLIKSMKAAGWDIPNPPASMFAWAKIPEAYREAGSMLFSRLLIEEAGVAVAPGIGFG
HHHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
EYGEGYVRIGLVENEHRIRQAARNVKKFIANADSILAKAHNKMEQA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STDFHRIRRLPPYVFEEVNKIKARLRAEGTDIIDFGMGNPDMPTPQHIVDKLIETARDP
CCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCC
KAGRYSASKGVPGLRKAMANYYGRRFGVKLNPDTEVIATLGSKEGFANLAQALTGPGDVI
CCCCCCCCCCCCHHHHHHHHHHHHHCCEEECCCHHHHHCCCCCCHHHHHHHHHCCCCCEE
ICPNPAYPIHAFGFIMAGGIIRHVPALSPEEYLSNISRAVKHSVPPPSVLILSYPSNPTA
ECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
QWVDLDFYKDAVALAKKHDLLVISDVAYGEIYFDNNPPPSILQVDGAKDIAVEVNSLSKT
EEEEHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCCCEEEECCCCEEEEEHHHHHHH
YAMAGWRVGMVVGNARICAALARVKSYLDYGAYTPVQVAAATALNGPQDCVDEIRGIYKS
HHHCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHH
RRDTLIKSMKAAGWDIPNPPASMFAWAKIPEAYREAGSMLFSRLLIEEAGVAVAPGIGFG
HHHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCC
EYGEGYVRIGLVENEHRIRQAARNVKKFIANADSILAKAHNKMEQA
CCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430; 9734305 [H]