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The map label for this gene is acdA [H]

Identifier: 16125559

GI number: 16125559

Start: 1457397

End: 1458611

Strand: Direct

Name: acdA [H]

Synonym: CC_1310

Alternate gene names: 16125559

Gene position: 1457397-1458611 (Clockwise)

Preceding gene: 16125558

Following gene: 16125560

Centisome position: 36.28

GC content: 65.02

Gene sequence:

>1215_bases
ATGAATCTCGACTTCTCGCCCGAGGACCTCGCCTTCCGCGACGAGGTCCGCGCCTTTATCGCCGAAAACTATCCGGCCGG
GCTGCGCGACAAGCAGGAGGAGGGCGAGGAGATGGCCAAGGAGGATTTCCTCTCCTGGCACCGCGTTCTCGCCAACAAGG
GCTGGGTGGCCCCCGCCTGGCCGACCCAGTACGGCGGACCGGGCTGGACCTCGGTGCAGCGCTATATCTGGTCGGAAGAA
ACCGCCCGCGCCGACTGCGTGCCGATCCTGCCGTTCGGCATCAACATGGTCGGCCCGGTGATCTACACCTTCGGCACGCC
CGAGCAAAAGGAACGCTTCCTGCCGGGGACCCTGTCGGGCGACATCTGGTGGTCTCAGGGCTACAGCGAGCCGGGCGCGG
GTTCCGACCTCGCCAGCCTGAAGACCAAGGCCGAGCGCTTCACCGGTGATGACGGCAAGGAATACTACCTGGTCAATGGT
CAGAAGACCTGGACCACCATGGCCCAGCACGGCGACTGGATCTTCTGTCTGGTCCGCACCGACCCGAACGCCAAGATTCA
GGAAGGCATCTCGTTCCTGCTGATCGACATGAAGTCGCCGGGCGTGACCGTGCGTCCGATCATCACCCTGGGCGGCGAGC
ACGAGGTCAACGAGGTCTGGTTCGAGAACGTCAAGGTGCCGGTCGAGAACCGCATCTACGACGAGAACAAGGGTTGGACC
TGCGCCAAGTTCCTGCTGGCTCACGAGCGCTCGGGCATCGCCGGTGTGGCGCGCTCCAAGCGCGGCATCGAGCGGATCCG
CCAGATCGCCTCGACCGAGCTGAGCGACGACGGCGACGCGCTGATCAAGGATCCGATGTTCAAGCGCAAGGTCGCCGAGC
TCGAGATCGACCTGACGGCGCTGGAGTACACTGAACTGCGCACCCTGGCCGGCGAAGCCGCGGGCCGCGGGCCGGGTCCG
GAGTCCAGCGTGCTCAAGATCAAGGGCACCGAGATCCAGCAACGCCTGACCGAGTTGGCGCTAGAGGCCGCTGGTCACTA
CGGCGCGCCTTACTTCCGGGGCTTCCCGAAGGACGGCGACAACGCCCATCCGATCGGTCCGGAGTTCGCGCACCGCGCCG
CGCCGACCTATTTCAACGTCCGCAAGACGTCGATCTACGGCGGCTCGAACGAAATCCAGCGCAACATCATCGCCAAGATG
GTGCTGGGCCTCTAA

Upstream 100 bases:

>100_bases
CGCTAACGTCATCTTTCCAAACGGCCGTTCGAGCCATATCATGCTCCCTGAAACGCAATAACGACCCCCATCCGAGGGGT
CGATTGAACGGGAGCTCGCC

Downstream 100 bases:

>100_bases
CGCGGGCTGTCATCCCGGGCGCGCCGGAGGCGTGACCCGGGACCACCCAATTCACCGACATTGACGATCCCGGCGCTCCG
CTTTGCTGCGGCCGGGATGA

Product: acyl-CoA dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNLDFSPEDLAFRDEVRAFIAENYPAGLRDKQEEGEEMAKEDFLSWHRVLANKGWVAPAWPTQYGGPGWTSVQRYIWSEE
TARADCVPILPFGINMVGPVIYTFGTPEQKERFLPGTLSGDIWWSQGYSEPGAGSDLASLKTKAERFTGDDGKEYYLVNG
QKTWTTMAQHGDWIFCLVRTDPNAKIQEGISFLLIDMKSPGVTVRPIITLGGEHEVNEVWFENVKVPVENRIYDENKGWT
CAKFLLAHERSGIAGVARSKRGIERIRQIASTELSDDGDALIKDPMFKRKVAELEIDLTALEYTELRTLAGEAAGRGPGP
ESSVLKIKGTEIQQRLTELALEAAGHYGAPYFRGFPKDGDNAHPIGPEFAHRAAPTYFNVRKTSIYGGSNEIQRNIIAKM
VLGL

Sequences:

>Translated_404_residues
MNLDFSPEDLAFRDEVRAFIAENYPAGLRDKQEEGEEMAKEDFLSWHRVLANKGWVAPAWPTQYGGPGWTSVQRYIWSEE
TARADCVPILPFGINMVGPVIYTFGTPEQKERFLPGTLSGDIWWSQGYSEPGAGSDLASLKTKAERFTGDDGKEYYLVNG
QKTWTTMAQHGDWIFCLVRTDPNAKIQEGISFLLIDMKSPGVTVRPIITLGGEHEVNEVWFENVKVPVENRIYDENKGWT
CAKFLLAHERSGIAGVARSKRGIERIRQIASTELSDDGDALIKDPMFKRKVAELEIDLTALEYTELRTLAGEAAGRGPGP
ESSVLKIKGTEIQQRLTELALEAAGHYGAPYFRGFPKDGDNAHPIGPEFAHRAAPTYFNVRKTSIYGGSNEIQRNIIAKM
VLGL
>Mature_404_residues
MNLDFSPEDLAFRDEVRAFIAENYPAGLRDKQEEGEEMAKEDFLSWHRVLANKGWVAPAWPTQYGGPGWTSVQRYIWSEE
TARADCVPILPFGINMVGPVIYTFGTPEQKERFLPGTLSGDIWWSQGYSEPGAGSDLASLKTKAERFTGDDGKEYYLVNG
QKTWTTMAQHGDWIFCLVRTDPNAKIQEGISFLLIDMKSPGVTVRPIITLGGEHEVNEVWFENVKVPVENRIYDENKGWT
CAKFLLAHERSGIAGVARSKRGIERIRQIASTELSDDGDALIKDPMFKRKVAELEIDLTALEYTELRTLAGEAAGRGPGP
ESSVLKIKGTEIQQRLTELALEAAGHYGAPYFRGFPKDGDNAHPIGPEFAHRAAPTYFNVRKTSIYGGSNEIQRNIIAKM
VLGL

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=411, Percent_Identity=28.7104622871046, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI226958412, Length=256, Percent_Identity=29.296875, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI4557231, Length=353, Percent_Identity=26.3456090651558, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI187960098, Length=353, Percent_Identity=26.3456090651558, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4501857, Length=404, Percent_Identity=25.7425742574257, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI226958414, Length=211, Percent_Identity=31.7535545023697, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4557233, Length=360, Percent_Identity=26.9444444444444, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI21361497, Length=369, Percent_Identity=24.6612466124661, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI76496475, Length=354, Percent_Identity=26.5536723163842, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI4557235, Length=304, Percent_Identity=26.6447368421053, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7656849, Length=365, Percent_Identity=25.7534246575342, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI211971008, Length=316, Percent_Identity=23.7341772151899, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI48976061, Length=313, Percent_Identity=23.0031948881789, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=265, Percent_Identity=26.0377358490566, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786223, Length=414, Percent_Identity=22.7053140096618, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17569725, Length=362, Percent_Identity=27.0718232044199, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17570075, Length=416, Percent_Identity=26.9230769230769, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=356, Percent_Identity=27.247191011236, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=198, Percent_Identity=30.3030303030303, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17538396, Length=255, Percent_Identity=28.6274509803922, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=360, Percent_Identity=26.3888888888889, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=198, Percent_Identity=28.2828282828283, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17506239, Length=253, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=211, Percent_Identity=28.436018957346, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=183, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71985184, Length=215, Percent_Identity=29.3023255813954, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=215, Percent_Identity=29.3023255813954, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355753, Length=220, Percent_Identity=31.3636363636364, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666513, Length=362, Percent_Identity=24.585635359116, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24660351, Length=315, Percent_Identity=26.984126984127, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI281363737, Length=351, Percent_Identity=24.7863247863248, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646207, Length=369, Percent_Identity=26.0162601626016, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356377, Length=368, Percent_Identity=24.7282608695652, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19920834, Length=308, Percent_Identity=25.974025974026, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 45048; Mature: 45048

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDFSPEDLAFRDEVRAFIAENYPAGLRDKQEEGEEMAKEDFLSWHRVLANKGWVAPAW
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTQYGGPGWTSVQRYIWSEETARADCVPILPFGINMVGPVIYTFGTPEQKERFLPGTLSG
CCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCEEEECCCCHHHHCCCCCCCCC
DIWWSQGYSEPGAGSDLASLKTKAERFTGDDGKEYYLVNGQKTWTTMAQHGDWIFCLVRT
CEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCEEEEEEEC
DPNAKIQEGISFLLIDMKSPGVTVRPIITLGGEHEVNEVWFENVKVPVENRIYDENKGWT
CCCCHHHCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCCHHHCEEECCCCCH
CAKFLLAHERSGIAGVARSKRGIERIRQIASTELSDDGDALIKDPMFKRKVAELEIDLTA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHEEEEEEE
LEYTELRTLAGEAAGRGPGPESSVLKIKGTEIQQRLTELALEAAGHYGAPYFRGFPKDGD
HHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
NAHPIGPEFAHRAAPTYFNVRKTSIYGGSNEIQRNIIAKMVLGL
CCCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLDFSPEDLAFRDEVRAFIAENYPAGLRDKQEEGEEMAKEDFLSWHRVLANKGWVAPAW
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PTQYGGPGWTSVQRYIWSEETARADCVPILPFGINMVGPVIYTFGTPEQKERFLPGTLSG
CCCCCCCCHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCEEEECCCCHHHHCCCCCCCCC
DIWWSQGYSEPGAGSDLASLKTKAERFTGDDGKEYYLVNGQKTWTTMAQHGDWIFCLVRT
CEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHCCCEEEEEEEC
DPNAKIQEGISFLLIDMKSPGVTVRPIITLGGEHEVNEVWFENVKVPVENRIYDENKGWT
CCCCHHHCCCEEEEEECCCCCEEEEEEEEECCCCCHHHHHHHCCCCCHHHCEEECCCCCH
CAKFLLAHERSGIAGVARSKRGIERIRQIASTELSDDGDALIKDPMFKRKVAELEIDLTA
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHEEEEEEE
LEYTELRTLAGEAAGRGPGPESSVLKIKGTEIQQRLTELALEAAGHYGAPYFRGFPKDGD
HHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCC
NAHPIGPEFAHRAAPTYFNVRKTSIYGGSNEIQRNIIAKMVLGL
CCCCCCHHHHHHCCCCEEEEEEEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]