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The map label for this gene is cobT [H]

Identifier: 16125558

GI number: 16125558

Start: 1456355

End: 1457245

Strand: Direct

Name: cobT [H]

Synonym: CC_1309

Alternate gene names: 16125558

Gene position: 1456355-1457245 (Clockwise)

Preceding gene: 16125555

Following gene: 16125559

Centisome position: 36.26

GC content: 71.49

Gene sequence:

>891_bases
ATGACCGATCAGACTGTCTCTCCCTTCGCCGATATCCGCCAACTCGCGAGCTCGCCGCCGCAGCCCGGGCCGACGCCCGC
GCTGGAGCAGGGCGGGCGGCTCGCCGAGATCGCCGCCTGGCTGACCGCCTGGACCGGCAAGACGCCGCCGGCCGTCAATC
GACCCGTCGTGGCCTTGTACGCCGGCGCGCGCCAGGGTGTGGGTCCGCGCGGGTGGGCGCGCGAGCGCCTGGAGGCGATC
GCGGCCGGCGGCGCCACCGTCTCTCGCCTGGCCGGTGTCCAGGGCGCGGGTCTGGAGGCCTTCGACCTGGCGATCGATCG
GCCTTCGCCGGACATGGTGAGCAAGGCCTCGATGAGCGAGAAGGAGGCGGCCGCCACTATGGCGTTCGGCATGGAGGCTC
TGGCCAAGCAGCCTGATCTGCTGATCCCCGGCGTCATCGCTGCGGAGCCTGCACGCACCGCCGCCGCCGTCTGTCTGGCG
CTGTTTGGCGGCGAGGCTTCCGACTGGTCAAGCGATCCTGAGCCGGTCGCGGCGGCGGTCGCCCGGGCGCGTGAAGAGGG
CATGGGCGATGACCCGCTTGAGATCCTGCGTCAACTCGGTGGCCGTGAAACCGCCGCCGTGGCCGGCGCCATTCTGGCCG
CGCGTGTGCAGAAGACGCCGGTGCTGCTGGACGGCTATGCCGCCTGCGCCGCCGCCGCGATTGTCCAGGCGGTCGAGCCC
ACCGCCATCGATCATTGCCTCGCCGCCCATGTCAGTCCGGCGAGGGGGCATGCCAAGCTGCTGGAAAAGCTGGGAAAGCA
GCCGCTCTTGAGCCTCGGTGCCGAGGATGAAGAGGGCGTTGGCGGCGTCTCGGCCCTGGCGCTGGTCAAGCTGGCCTGCG
AGGCCCGATAG

Upstream 100 bases:

>100_bases
GCGTTCGTCGTCATGGTCCAAACATCTCCGGTCCTGGTCAGGCGCGCAAGGGCTTGGGGCTGGGGCTTGCTTTGGGCGGC
GAGCGGTTTAAGTCCGCTCC

Downstream 100 bases:

>100_bases
GCGGTTTCGCGGGGCCGCTAAGTGAACGCGGATAATATTCGCTTCCGTTGACGCTAACGTCATCTTTCCAAACGGCCGTT
CGAGCCATATCATGCTCCCT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MTDQTVSPFADIRQLASSPPQPGPTPALEQGGRLAEIAAWLTAWTGKTPPAVNRPVVALYAGARQGVGPRGWARERLEAI
AAGGATVSRLAGVQGAGLEAFDLAIDRPSPDMVSKASMSEKEAAATMAFGMEALAKQPDLLIPGVIAAEPARTAAAVCLA
LFGGEASDWSSDPEPVAAAVARAREEGMGDDPLEILRQLGGRETAAVAGAILAARVQKTPVLLDGYAACAAAAIVQAVEP
TAIDHCLAAHVSPARGHAKLLEKLGKQPLLSLGAEDEEGVGGVSALALVKLACEAR

Sequences:

>Translated_296_residues
MTDQTVSPFADIRQLASSPPQPGPTPALEQGGRLAEIAAWLTAWTGKTPPAVNRPVVALYAGARQGVGPRGWARERLEAI
AAGGATVSRLAGVQGAGLEAFDLAIDRPSPDMVSKASMSEKEAAATMAFGMEALAKQPDLLIPGVIAAEPARTAAAVCLA
LFGGEASDWSSDPEPVAAAVARAREEGMGDDPLEILRQLGGRETAAVAGAILAARVQKTPVLLDGYAACAAAAIVQAVEP
TAIDHCLAAHVSPARGHAKLLEKLGKQPLLSLGAEDEEGVGGVSALALVKLACEAR
>Mature_295_residues
TDQTVSPFADIRQLASSPPQPGPTPALEQGGRLAEIAAWLTAWTGKTPPAVNRPVVALYAGARQGVGPRGWARERLEAIA
AGGATVSRLAGVQGAGLEAFDLAIDRPSPDMVSKASMSEKEAAATMAFGMEALAKQPDLLIPGVIAAEPARTAAAVCLAL
FGGEASDWSSDPEPVAAAVARAREEGMGDDPLEILRQLGGRETAAVAGAILAARVQKTPVLLDGYAACAAAAIVQAVEPT
AIDHCLAAHVSPARGHAKLLEKLGKQPLLSLGAEDEEGVGGVSALALVKLACEAR

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 30139; Mature: 30007

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQTVSPFADIRQLASSPPQPGPTPALEQGGRLAEIAAWLTAWTGKTPPAVNRPVVALY
CCCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEE
AGARQGVGPRGWARERLEAIAAGGATVSRLAGVQGAGLEAFDLAIDRPSPDMVSKASMSE
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHEEEEECCCCHHHHHHHHHHH
KEAAATMAFGMEALAKQPDLLIPGVIAAEPARTAAAVCLALFGGEASDWSSDPEPVAAAV
HHHHHHHHHHHHHHHCCCCEECCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ARAREEGMGDDPLEILRQLGGRETAAVAGAILAARVQKTPVLLDGYAACAAAAIVQAVEP
HHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCH
TAIDHCLAAHVSPARGHAKLLEKLGKQPLLSLGAEDEEGVGGVSALALVKLACEAR
HHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDQTVSPFADIRQLASSPPQPGPTPALEQGGRLAEIAAWLTAWTGKTPPAVNRPVVALY
CCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEE
AGARQGVGPRGWARERLEAIAAGGATVSRLAGVQGAGLEAFDLAIDRPSPDMVSKASMSE
CCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHEEEEECCCCHHHHHHHHHHH
KEAAATMAFGMEALAKQPDLLIPGVIAAEPARTAAAVCLALFGGEASDWSSDPEPVAAAV
HHHHHHHHHHHHHHHCCCCEECCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
ARAREEGMGDDPLEILRQLGGRETAAVAGAILAARVQKTPVLLDGYAACAAAAIVQAVEP
HHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHCH
TAIDHCLAAHVSPARGHAKLLEKLGKQPLLSLGAEDEEGVGGVSALALVKLACEAR
HHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA