| Definition | Caulobacter crescentus CB15 chromosome, complete genome. |
|---|---|
| Accession | NC_002696 |
| Length | 4,016,947 |
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The map label for this gene is gno [H]
Identifier: 16125535
GI number: 16125535
Start: 1432769
End: 1433551
Strand: Direct
Name: gno [H]
Synonym: CC_1286
Alternate gene names: 16125535
Gene position: 1432769-1433551 (Clockwise)
Preceding gene: 16125534
Following gene: 16125536
Centisome position: 35.67
GC content: 67.94
Gene sequence:
>783_bases ATGTCATCGCCCCTGCACAAGCTCTTTGACCTGACGGGCCGGGTGGCGATCGTGACGGGGGGCTCGCGGGGTCTTGGTCT GCAGATCGCCCGGGCGTTGGCGGAGTATGGCGCAGCGGTGGCGCTGGTCGCCCGCAAGCAAGGCGAACTGGACGCCGCCG TCGCGGCCCTGACCGCCGAAGGGCGCACCGCCGTGGGTCTTGTGGCCGATCTCGGGCAGGCGGGCTCAGCGCAAGACCTG ACCGCGCGCGTGCTCGAGCGTTTCGGGCGGATCGACATTCTGGTCAACAACGCCGGCGCCGCCTGGGGTGCGCCGGCCGA GGACTATCCGCTTGAGGGCTGGAACAAGGTCATGGATCTGAACGTCACCGGCCTTTTCCTCCTCACCCAGGCCGTCGCCC GCGAGGCGTTCCTGAAGCAGGGCAAGGGGGCGGTCGTGAACGTCGCCTCGATCGAGGGACTGCAGGGACACCATCACAGC CAGCTCGGCACCATCGCCTACAACACGGCCAAGGGTGCGGTGATCAACATGACCCGGGCGTTGGCGGCGGAGTGGGGACC AAGGAACATCCGGGTCAACGCGGTGGCGCCAGGCTACTTCCCCTCGAAGATGACCATGACGACCCTGGGCCAGCACGGCG ACGACATGCTGCGCCAGACGCCGCTTGGCAAACTGGGCGGGGACACTGACCTGATGGGGCCGGCGCTCCTGTTGGCCTCC GACGCCGGCGGCCACATCACCGGTCAGATCATCGTCGTCGACGGCGGCATGACGATCATCTGA
Upstream 100 bases:
>100_bases TTTGCGCATGCCAGACTTTTCGCCAATGCGACCGCCCCGGCCTCGGCCTGAGGGCGGTCCGCGAACATGGCGTGCGCCCG TCCTTTCTTTGGAGACCCAG
Downstream 100 bases:
>100_bases CCGTCGACAGGCGCCTTTCAGCGGATCTCGCTCTCGTTTCGCGTTGAGGCGCAGGGGAGGGAGCGCCTCGAAGCTGGACG CTCAGGCGCTGTAATCAGCC
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MSSPLHKLFDLTGRVAIVTGGSRGLGLQIARALAEYGAAVALVARKQGELDAAVAALTAEGRTAVGLVADLGQAGSAQDL TARVLERFGRIDILVNNAGAAWGAPAEDYPLEGWNKVMDLNVTGLFLLTQAVAREAFLKQGKGAVVNVASIEGLQGHHHS QLGTIAYNTAKGAVINMTRALAAEWGPRNIRVNAVAPGYFPSKMTMTTLGQHGDDMLRQTPLGKLGGDTDLMGPALLLAS DAGGHITGQIIVVDGGMTII
Sequences:
>Translated_260_residues MSSPLHKLFDLTGRVAIVTGGSRGLGLQIARALAEYGAAVALVARKQGELDAAVAALTAEGRTAVGLVADLGQAGSAQDL TARVLERFGRIDILVNNAGAAWGAPAEDYPLEGWNKVMDLNVTGLFLLTQAVAREAFLKQGKGAVVNVASIEGLQGHHHS QLGTIAYNTAKGAVINMTRALAAEWGPRNIRVNAVAPGYFPSKMTMTTLGQHGDDMLRQTPLGKLGGDTDLMGPALLLAS DAGGHITGQIIVVDGGMTII >Mature_259_residues SSPLHKLFDLTGRVAIVTGGSRGLGLQIARALAEYGAAVALVARKQGELDAAVAALTAEGRTAVGLVADLGQAGSAQDLT ARVLERFGRIDILVNNAGAAWGAPAEDYPLEGWNKVMDLNVTGLFLLTQAVAREAFLKQGKGAVVNVASIEGLQGHHHSQ LGTIAYNTAKGAVINMTRALAAEWGPRNIRVNAVAPGYFPSKMTMTTLGQHGDDMLRQTPLGKLGGDTDLMGPALLLASD AGGHITGQIIVVDGGMTII
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=258, Percent_Identity=36.8217054263566, Blast_Score=144, Evalue=1e-34, Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=32.183908045977, Blast_Score=129, Evalue=3e-30, Organism=Homo sapiens, GI10190704, Length=250, Percent_Identity=33.2, Blast_Score=126, Evalue=2e-29, Organism=Homo sapiens, GI5031737, Length=263, Percent_Identity=33.0798479087452, Blast_Score=123, Evalue=1e-28, Organism=Homo sapiens, GI126723750, Length=262, Percent_Identity=32.0610687022901, Blast_Score=116, Evalue=2e-26, Organism=Homo sapiens, GI40254992, Length=247, Percent_Identity=31.9838056680162, Blast_Score=113, Evalue=2e-25, Organism=Homo sapiens, GI33667109, Length=205, Percent_Identity=35.609756097561, Blast_Score=112, Evalue=2e-25, Organism=Homo sapiens, GI7705925, Length=258, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI126723191, Length=195, Percent_Identity=38.974358974359, Blast_Score=112, Evalue=4e-25, Organism=Homo sapiens, GI15277342, Length=255, Percent_Identity=30.1960784313725, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI59889578, Length=236, Percent_Identity=30.5084745762712, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI4503301, Length=266, Percent_Identity=26.6917293233083, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=29.9242424242424, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=29.0476190476191, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI7706318, Length=225, Percent_Identity=30.6666666666667, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=25.78125, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI4504505, Length=220, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI83715985, Length=189, Percent_Identity=30.1587301587302, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI31542939, Length=201, Percent_Identity=29.8507462686567, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI4503817, Length=205, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=2e-12, Organism=Escherichia coli, GI1789208, Length=251, Percent_Identity=37.8486055776892, Blast_Score=151, Evalue=4e-38, Organism=Escherichia coli, GI1790717, Length=262, Percent_Identity=33.206106870229, Blast_Score=141, Evalue=5e-35, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=34.6303501945525, Blast_Score=139, Evalue=2e-34, Organism=Escherichia coli, GI1787335, Length=252, Percent_Identity=33.7301587301587, Blast_Score=133, Evalue=1e-32, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=32.8, Blast_Score=116, Evalue=2e-27, Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=31.5175097276265, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=30.3846153846154, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI1789378, Length=253, Percent_Identity=33.596837944664, Blast_Score=90, Evalue=1e-19, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=31.8897637795276, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787526, Length=192, Percent_Identity=33.8541666666667, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=27.2030651340996, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=28.0487804878049, Blast_Score=65, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=35.2713178294574, Blast_Score=129, Evalue=1e-30, Organism=Caenorhabditis elegans, GI17560676, Length=265, Percent_Identity=34.7169811320755, Blast_Score=126, Evalue=1e-29, Organism=Caenorhabditis elegans, GI25147288, Length=250, Percent_Identity=31.6, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=3e-26, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=30.7407407407407, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=33.955223880597, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17560332, Length=269, Percent_Identity=33.457249070632, Blast_Score=108, Evalue=3e-24, Organism=Caenorhabditis elegans, GI17562906, Length=268, Percent_Identity=32.4626865671642, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI115534694, Length=260, Percent_Identity=31.1538461538462, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=31.4814814814815, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=30.5970149253731, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17531453, Length=273, Percent_Identity=31.1355311355311, Blast_Score=103, Evalue=7e-23, Organism=Caenorhabditis elegans, GI71994600, Length=260, Percent_Identity=31.1538461538462, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=30.1115241635688, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17538480, Length=270, Percent_Identity=29.2592592592593, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=31.25, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.7313432835821, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=31.7164179104478, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17562904, Length=272, Percent_Identity=29.4117647058824, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI17536025, Length=263, Percent_Identity=28.1368821292776, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17560220, Length=268, Percent_Identity=28.7313432835821, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI72000259, Length=266, Percent_Identity=29.3233082706767, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=30.188679245283, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17536651, Length=262, Percent_Identity=25.1908396946565, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17565030, Length=270, Percent_Identity=31.4814814814815, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI17561272, Length=263, Percent_Identity=31.1787072243346, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=27.9850746268657, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI71997099, Length=255, Percent_Identity=28.2352941176471, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17538182, Length=218, Percent_Identity=30.7339449541284, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71982365, Length=198, Percent_Identity=28.2828282828283, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17568967, Length=226, Percent_Identity=29.646017699115, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17558628, Length=199, Percent_Identity=28.1407035175879, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=30.0970873786408, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI193203117, Length=208, Percent_Identity=26.4423076923077, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193203115, Length=197, Percent_Identity=26.9035532994924, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=258, Percent_Identity=27.1317829457364, Blast_Score=93, Evalue=4e-20, Organism=Saccharomyces cerevisiae, GI6322861, Length=208, Percent_Identity=29.3269230769231, Blast_Score=73, Evalue=6e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=202, Percent_Identity=31.6831683168317, Blast_Score=66, Evalue=7e-12, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=36.1867704280156, Blast_Score=135, Evalue=4e-32, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=34.6456692913386, Blast_Score=127, Evalue=8e-30, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=34.4, Blast_Score=117, Evalue=6e-27, Organism=Drosophila melanogaster, GI21357041, Length=255, Percent_Identity=34.1176470588235, Blast_Score=115, Evalue=2e-26, Organism=Drosophila melanogaster, GI24644339, Length=260, Percent_Identity=31.5384615384615, Blast_Score=115, Evalue=3e-26, Organism=Drosophila melanogaster, GI24639444, Length=250, Percent_Identity=32.4, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=29.7297297297297, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24643142, Length=252, Percent_Identity=31.3492063492063, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21358495, Length=203, Percent_Identity=30.0492610837438, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI17737361, Length=260, Percent_Identity=26.9230769230769, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI18859837, Length=204, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI24584748, Length=197, Percent_Identity=29.4416243654822, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24641232, Length=216, Percent_Identity=28.2407407407407, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI161076933, Length=197, Percent_Identity=29.4416243654822, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24656154, Length=208, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI19922628, Length=208, Percent_Identity=28.8461538461538, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28574402, Length=210, Percent_Identity=28.0952380952381, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584744, Length=207, Percent_Identity=28.5024154589372, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI116007236, Length=200, Percent_Identity=27, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 26911; Mature: 26780
Theoretical pI: Translated: 7.18; Mature: 7.18
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSPLHKLFDLTGRVAIVTGGSRGLGLQIARALAEYGAAVALVARKQGELDAAVAALTAE CCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCC GRTAVGLVADLGQAGSAQDLTARVLERFGRIDILVNNAGAAWGAPAEDYPLEGWNKVMDL CCEEEEHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEC NVTGLFLLTQAVAREAFLKQGKGAVVNVASIEGLQGHHHSQLGTIAYNTAKGAVINMTRA CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCEEHHHHH LAAEWGPRNIRVNAVAPGYFPSKMTMTTLGQHGDDMLRQTPLGKLGGDTDLMGPALLLAS HHHCCCCCEEEEEEEECCCCCCCCHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEE DAGGHITGQIIVVDGGMTII CCCCEEEEEEEEEECCEEEC >Mature Secondary Structure SSPLHKLFDLTGRVAIVTGGSRGLGLQIARALAEYGAAVALVARKQGELDAAVAALTAE CCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHCCC GRTAVGLVADLGQAGSAQDLTARVLERFGRIDILVNNAGAAWGAPAEDYPLEGWNKVMDL CCEEEEHHHHCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEC NVTGLFLLTQAVAREAFLKQGKGAVVNVASIEGLQGHHHSQLGTIAYNTAKGAVINMTRA CCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCEEEEECCCCCEEHHHHH LAAEWGPRNIRVNAVAPGYFPSKMTMTTLGQHGDDMLRQTPLGKLGGDTDLMGPALLLAS HHHCCCCCEEEEEEEECCCCCCCCHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEEEE DAGGHITGQIIVVDGGMTII CCCCEEEEEEEEEECCEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]