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The map label for this gene is desR [H]

Identifier: 16125402

GI number: 16125402

Start: 1308896

End: 1309501

Strand: Direct

Name: desR [H]

Synonym: CC_1150

Alternate gene names: 16125402

Gene position: 1308896-1309501 (Clockwise)

Preceding gene: 16125401

Following gene: 16125403

Centisome position: 32.58

GC content: 70.63

Gene sequence:

>606_bases
TTGATCCGCGTCGTTATCGCCGAAGACCAGAAGATGGTGCTGGGGGCCCTCAGCGCCCTTCTGGAAATGGAGGGCGACAT
CCAGGTGGTCGGCCGCGCGCCCGACGGCGCTGTCGCCCTGGACCTTGTCCGCGCCGAGAAGCCCGACGTGCTGATCTCCG
ACATCGAGATGCCCAACCTGACCGGCATTGACGTCGCCGCGCGTCTGAAGGCCGACGGCGCCGGCACCCGGGTGCTGATC
GTCACGACCTTCGGCCGGCCCGGTTATCTGCGCCGGGCGATGGACGCGGGCGTGAAGGGCTATCTGCTGAAAGACGGGCC
CAGCAGCGTGCTGGCGGCGGCGGTGCGGACCATCGCCGCCGGCGGCCGCGCCATCGCGCCGGAGCTGTCGGAAGCGGTCT
GGGACGCCGAGCCCGATCCCCTGACCGATCGCGAGCGCGAGATCCTGCGGCTGGCGGAGGAGGGGCGCTCCAACAAGGAC
ATCGCCGACGTCCTGGACCTCTCGCCCGGCACCGTCCGCAACTACCTCTCCGAGGCGGCGCAGAAGCTGGGCGCCGCGAA
CCGCGTGGAGGCGGGCCGTATCGCGCGTTCGAACGGCTGGCTGTAA

Upstream 100 bases:

>100_bases
GCCTGGCCGCGATCGGCGGAACCCTGGACGTCAAATCCGACAAGGCCGGCACGCGCCTCGTCGCCACAGCGCCGCTGCGC
GCTCAAGGGGAGGGCGTGTC

Downstream 100 bases:

>100_bases
CGTCGAGCGATGATCGTTTCCTCGACCACGGACTTTCGCGAAGCGGCGCGGCGCAGGCTGCCCCGGTTCCTGTTCGACTA
TATCGACGGCGGCGCCTATG

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 201; Mature: 201

Protein sequence:

>201_residues
MIRVVIAEDQKMVLGALSALLEMEGDIQVVGRAPDGAVALDLVRAEKPDVLISDIEMPNLTGIDVAARLKADGAGTRVLI
VTTFGRPGYLRRAMDAGVKGYLLKDGPSSVLAAAVRTIAAGGRAIAPELSEAVWDAEPDPLTDREREILRLAEEGRSNKD
IADVLDLSPGTVRNYLSEAAQKLGAANRVEAGRIARSNGWL

Sequences:

>Translated_201_residues
MIRVVIAEDQKMVLGALSALLEMEGDIQVVGRAPDGAVALDLVRAEKPDVLISDIEMPNLTGIDVAARLKADGAGTRVLI
VTTFGRPGYLRRAMDAGVKGYLLKDGPSSVLAAAVRTIAAGGRAIAPELSEAVWDAEPDPLTDREREILRLAEEGRSNKD
IADVLDLSPGTVRNYLSEAAQKLGAANRVEAGRIARSNGWL
>Mature_201_residues
MIRVVIAEDQKMVLGALSALLEMEGDIQVVGRAPDGAVALDLVRAEKPDVLISDIEMPNLTGIDVAARLKADGAGTRVLI
VTTFGRPGYLRRAMDAGVKGYLLKDGPSSVLAAAVRTIAAGGRAIAPELSEAVWDAEPDPLTDREREILRLAEEGRSNKD
IADVLDLSPGTVRNYLSEAAQKLGAANRVEAGRIARSNGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=33, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788521, Length=198, Percent_Identity=33.3333333333333, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788222, Length=208, Percent_Identity=27.8846153846154, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786747, Length=194, Percent_Identity=28.3505154639175, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787473, Length=199, Percent_Identity=29.6482412060301, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788712, Length=199, Percent_Identity=25.6281407035176, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788546, Length=196, Percent_Identity=26.0204081632653, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21323; Mature: 21323

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVVIAEDQKMVLGALSALLEMEGDIQVVGRAPDGAVALDLVRAEKPDVLISDIEMPNL
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCC
TGIDVAARLKADGAGTRVLIVTTFGRPGYLRRAMDAGVKGYLLKDGPSSVLAAAVRTIAA
CCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHC
GGRAIAPELSEAVWDAEPDPLTDREREILRLAEEGRSNKDIADVLDLSPGTVRNYLSEAA
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHH
QKLGAANRVEAGRIARSNGWL
HHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIRVVIAEDQKMVLGALSALLEMEGDIQVVGRAPDGAVALDLVRAEKPDVLISDIEMPNL
CEEEEEECCCHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCCCCEEEECCCCCCC
TGIDVAARLKADGAGTRVLIVTTFGRPGYLRRAMDAGVKGYLLKDGPSSVLAAAVRTIAA
CCCCCEEEEECCCCCCEEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHC
GGRAIAPELSEAVWDAEPDPLTDREREILRLAEEGRSNKDIADVLDLSPGTVRNYLSEAA
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHH
QKLGAANRVEAGRIARSNGWL
HHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]