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The map label for this gene is hprK [H]

Identifier: 16124494

GI number: 16124494

Start: 254808

End: 255242

Strand: Direct

Name: hprK [H]

Synonym: CC_0239

Alternate gene names: 16124494

Gene position: 254808-255242 (Clockwise)

Preceding gene: 16124493

Following gene: 16124495

Centisome position: 6.34

GC content: 68.05

Gene sequence:

>435_bases
ATGATCCGCCACGGCGGCCTGATCGCTCTGCGCCACCAAGGGCTTTGGCGCGGCGCGCTGATCGAAGGCCCGTCGGGCGC
CGGCAAAAGCGACCTGGCCCTGCGCGCTCTGGATCAGGGCTTCCGTCTTGTCGCCGATGATCGCGTCGTGACTTTCGCTG
CGGGCGGGCGCCTCTACGGACGCGCGCCCGAGACCTTGGCGGGCCTCATCGAGGTGCGCGGGCTCGGCGTGGTCACCGCC
GCCGCCGTTTCCTTCGCGGAGATCGCGCTGGTCATCCGCTGCGTCGACACTCCAGGCCGGGTCGAAAGACTGCCCGAGCC
CCGTTTCGAGCGGATTGCGGGCGTGGATGTTCCCGTTTTCGACCTGTGGCCGCCAGAACCCGCCGCGCCGGCGAAAATCA
GACGCATGATGCAGTCTCTTGGAGTCCAATCCTAA

Upstream 100 bases:

>100_bases
TCGAGACCCATGGCGGTACGGTCCACGCCGAGAACCGCAAGGACGCGAACGGGGCGGTGGTCGGCGCCCGCTTCGTCGTC
GAATTGCCGGACGCGCGCGA

Downstream 100 bases:

>100_bases
CGGGCGTATCAAGACCGCCCGCGCGACACTCTCCCGGTCGTGGCGGGAATGGGGATCCCGTTTGAGATACAAGGCATGAT
CGGGCTCGTGATTGTGACGC

Product: HPr kinase/phosphatase-like protein

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MIRHGGLIALRHQGLWRGALIEGPSGAGKSDLALRALDQGFRLVADDRVVTFAAGGRLYGRAPETLAGLIEVRGLGVVTA
AAVSFAEIALVIRCVDTPGRVERLPEPRFERIAGVDVPVFDLWPPEPAAPAKIRRMMQSLGVQS

Sequences:

>Translated_144_residues
MIRHGGLIALRHQGLWRGALIEGPSGAGKSDLALRALDQGFRLVADDRVVTFAAGGRLYGRAPETLAGLIEVRGLGVVTA
AAVSFAEIALVIRCVDTPGRVERLPEPRFERIAGVDVPVFDLWPPEPAAPAKIRRMMQSLGVQS
>Mature_144_residues
MIRHGGLIALRHQGLWRGALIEGPSGAGKSDLALRALDQGFRLVADDRVVTFAAGGRLYGRAPETLAGLIEVRGLGVVTA
AAVSFAEIALVIRCVDTPGRVERLPEPRFERIAGVDVPVFDLWPPEPAAPAKIRRMMQSLGVQS

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 15402; Mature: 15402

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRHGGLIALRHQGLWRGALIEGPSGAGKSDLALRALDQGFRLVADDRVVTFAAGGRLYG
CCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEECCEEEEEECCCEEEC
RAPETLAGLIEVRGLGVVTAAAVSFAEIALVIRCVDTPGRVERLPEPRFERIAGVDVPVF
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCHHHCCCCCHHHHHCCCCCCEE
DLWPPEPAAPAKIRRMMQSLGVQS
ECCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRHGGLIALRHQGLWRGALIEGPSGAGKSDLALRALDQGFRLVADDRVVTFAAGGRLYG
CCCCCCEEEEECCCCCCCEEEECCCCCCCCHHHHHHHHCCCEEEECCEEEEEECCCEEEC
RAPETLAGLIEVRGLGVVTAAAVSFAEIALVIRCVDTPGRVERLPEPRFERIAGVDVPVF
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHHEEEECCCCCHHHCCCCCHHHHHCCCCCCEE
DLWPPEPAAPAKIRRMMQSLGVQS
ECCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12466555 [H]