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The map label for this gene is chvG [H]

Identifier: 16124493

GI number: 16124493

Start: 253207

End: 254811

Strand: Direct

Name: chvG [H]

Synonym: CC_0238

Alternate gene names: 16124493

Gene position: 253207-254811 (Clockwise)

Preceding gene: 16124492

Following gene: 16124494

Centisome position: 6.3

GC content: 67.98

Gene sequence:

>1605_bases
TTGGCTACCGTTATCGCGAAGCCTGAGGCGATCGCGCCCGAGCCCAAGCGGCGCTTCACCTGGCCGCGCGGGTCGCGGCT
GGGGCGGCTGATCGTTGTCCTGAACGTCGTGGCCCTGGCGATCGTCATCGTCGGGGCCTTGATCCTCAACGAGCTGCGCA
ACGGCCTGGTCAATGCGCGGATCGACAGCCTGTCGACCCAGGGCGAGCTGATCGCCAACGTCATCGACCAGTCGGCCACG
GTCGGTGAGCCCGAGCCGGCGCTGGACCCCTACACGGCCAGCCAGATTTTCCAGCTGTTGTTCATTCCGCGCTCGCAACG
CGCGCGGCTGTTCGACGCCCAAGGCAAGGCGCTGGCCGACTCCTTCGTGGTGGCCGATCGGGTCGACTGGAAGGTTCTGC
CGCCGGCCCGAAAGCCGGATCAGAAGGACGATGACGCGCGGACGACGCCCGATCGCGCCGCGAAGGCCAAACGCGCCCAG
GAGGCTTTGGCCAACGAGATCGCTCAGGCCATGCGCGGCCGAACCGTCGCGGGCACCCGGATCGCCGAAAACGGCGAGCG
GGTCGTGTCGGTGTCCATCCCGATCCAACATGTGAAGGCGGTGTTGGGCGTCCTGACACTGGAGGCCAGCGACGTCGACG
AGATTATCGCCGCCCAGCGCAAGGCTCTGCTGCCGTTCATCGCGGTGGCCATGCTGGCGATCCTGACCTCCAGCGTCCTG
CTGCACAGGCTGATCGCCGTGCCGGTTCTGCGCCTGGCCCGTGCGGCGGACCATGTGCGCCTGCAAGGCGCTCGCGCCAT
CTCGCTTCCCGACCTCTCGGAACGGAAGGACGAACTGGGCGACCTGTCACGCTCGCTGGAGGACATGACCCATTCGCTGT
CCGAGCGGATGGACGCCATCGAGCGCTTCGCCGCCGACGTTGCGCACGAGATCAAGAATCCGCTGACCTCGATCCGCTCG
GCGATCGAGACCCTGGACCTCGTCACCGAGCCGGCCGCCCGCGCGAGGCTGCTGGCCATCCTGCAGAACGACGTCAATCG
CCTGGACCGGCTCGTCACCGACATCTCCAACGCCTCGCGCCTCGACGCGGAGCTGTCGCGCGAGCATCCCAAGGCGCTCG
ATCTGGGGCGTCTTTTGACGGAGGTGGTGAGCCTTTACGAGAACCAGTGGCGCCCCGGCGACGCGCCGGGCAGCGTGCGC
GTGTCCCTCAGTCTCGCGGACCCCTCACAACCGGCGATCATCCTGGGGCGCGAGACGCCGATCGGGCAGGTGTTCCGCAA
CCTGATCGACAATGCGCGCTCATTCAGCCCGGCCGACGGCGAGGTGCGCGTGACCTTGTCGCGGACCCGGGGCGGGCTGA
TCGCGGCTGTCGAGGACGACGGGCCGGGCATGCCGCCTGAAAATCTCGAGACCATCTTCGAGCGATTTTACACCTCGCGC
CCCAAGGGACGGGCGTTCGGCGGCAATTCGGGCCTGGGCCTGTCGATCGCCCGTCAGATCGTCGAGACCCATGGCGGTAC
GGTCCACGCCGAGAACCGCAAGGACGCGAACGGGGCGGTGGTCGGCGCCCGCTTCGTCGTCGAATTGCCGGACGCGCGCG
AATGA

Upstream 100 bases:

>100_bases
TATGTCGACGACCGCACGATCGACAGCCACATCAAGCGCATGCGCAAGAAGTTCCGTCAGGTCGACCCGGAATTCGACTC
CATCGAGACCCTGTACGGCG

Downstream 100 bases:

>100_bases
TCCGCCACGGCGGCCTGATCGCTCTGCGCCACCAAGGGCTTTGGCGCGGCGCGCTGATCGAAGGCCCGTCGGGCGCCGGC
AAAAGCGACCTGGCCCTGCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 534; Mature: 533

Protein sequence:

>534_residues
MATVIAKPEAIAPEPKRRFTWPRGSRLGRLIVVLNVVALAIVIVGALILNELRNGLVNARIDSLSTQGELIANVIDQSAT
VGEPEPALDPYTASQIFQLLFIPRSQRARLFDAQGKALADSFVVADRVDWKVLPPARKPDQKDDDARTTPDRAAKAKRAQ
EALANEIAQAMRGRTVAGTRIAENGERVVSVSIPIQHVKAVLGVLTLEASDVDEIIAAQRKALLPFIAVAMLAILTSSVL
LHRLIAVPVLRLARAADHVRLQGARAISLPDLSERKDELGDLSRSLEDMTHSLSERMDAIERFAADVAHEIKNPLTSIRS
AIETLDLVTEPAARARLLAILQNDVNRLDRLVTDISNASRLDAELSREHPKALDLGRLLTEVVSLYENQWRPGDAPGSVR
VSLSLADPSQPAIILGRETPIGQVFRNLIDNARSFSPADGEVRVTLSRTRGGLIAAVEDDGPGMPPENLETIFERFYTSR
PKGRAFGGNSGLGLSIARQIVETHGGTVHAENRKDANGAVVGARFVVELPDARE

Sequences:

>Translated_534_residues
MATVIAKPEAIAPEPKRRFTWPRGSRLGRLIVVLNVVALAIVIVGALILNELRNGLVNARIDSLSTQGELIANVIDQSAT
VGEPEPALDPYTASQIFQLLFIPRSQRARLFDAQGKALADSFVVADRVDWKVLPPARKPDQKDDDARTTPDRAAKAKRAQ
EALANEIAQAMRGRTVAGTRIAENGERVVSVSIPIQHVKAVLGVLTLEASDVDEIIAAQRKALLPFIAVAMLAILTSSVL
LHRLIAVPVLRLARAADHVRLQGARAISLPDLSERKDELGDLSRSLEDMTHSLSERMDAIERFAADVAHEIKNPLTSIRS
AIETLDLVTEPAARARLLAILQNDVNRLDRLVTDISNASRLDAELSREHPKALDLGRLLTEVVSLYENQWRPGDAPGSVR
VSLSLADPSQPAIILGRETPIGQVFRNLIDNARSFSPADGEVRVTLSRTRGGLIAAVEDDGPGMPPENLETIFERFYTSR
PKGRAFGGNSGLGLSIARQIVETHGGTVHAENRKDANGAVVGARFVVELPDARE
>Mature_533_residues
ATVIAKPEAIAPEPKRRFTWPRGSRLGRLIVVLNVVALAIVIVGALILNELRNGLVNARIDSLSTQGELIANVIDQSATV
GEPEPALDPYTASQIFQLLFIPRSQRARLFDAQGKALADSFVVADRVDWKVLPPARKPDQKDDDARTTPDRAAKAKRAQE
ALANEIAQAMRGRTVAGTRIAENGERVVSVSIPIQHVKAVLGVLTLEASDVDEIIAAQRKALLPFIAVAMLAILTSSVLL
HRLIAVPVLRLARAADHVRLQGARAISLPDLSERKDELGDLSRSLEDMTHSLSERMDAIERFAADVAHEIKNPLTSIRSA
IETLDLVTEPAARARLLAILQNDVNRLDRLVTDISNASRLDAELSREHPKALDLGRLLTEVVSLYENQWRPGDAPGSVRV
SLSLADPSQPAIILGRETPIGQVFRNLIDNARSFSPADGEVRVTLSRTRGGLIAAVEDDGPGMPPENLETIFERFYTSRP
KGRAFGGNSGLGLSIARQIVETHGGTVHAENRKDANGAVVGARFVVELPDARE

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=299, Percent_Identity=27.7591973244147, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=286, Percent_Identity=28.3216783216783, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786912, Length=248, Percent_Identity=29.8387096774194, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790861, Length=388, Percent_Identity=27.0618556701031, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789403, Length=303, Percent_Identity=32.013201320132, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1786783, Length=311, Percent_Identity=27.9742765273312, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787894, Length=224, Percent_Identity=31.25, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=244, Percent_Identity=27.8688524590164, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789808, Length=387, Percent_Identity=24.2894056847545, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=246, Percent_Identity=28.4552845528455, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=286, Percent_Identity=23.7762237762238, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787374, Length=240, Percent_Identity=29.5833333333333, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788549, Length=275, Percent_Identity=25.0909090909091, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790300, Length=217, Percent_Identity=29.0322580645161, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87082128, Length=312, Percent_Identity=26.2820512820513, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57914; Mature: 57783

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVIAKPEAIAPEPKRRFTWPRGSRLGRLIVVLNVVALAIVIVGALILNELRNGLVNAR
CCCEECCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSLSTQGELIANVIDQSATVGEPEPALDPYTASQIFQLLFIPRSQRARLFDAQGKALAD
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCHHHH
SFVVADRVDWKVLPPARKPDQKDDDARTTPDRAAKAKRAQEALANEIAQAMRGRTVAGTR
HHHHCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
IAENGERVVSVSIPIQHVKAVLGVLTLEASDVDEIIAAQRKALLPFIAVAMLAILTSSVL
HHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHRLIAVPVLRLARAADHVRLQGARAISLPDLSERKDELGDLSRSLEDMTHSLSERMDAI
HHHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERFAADVAHEIKNPLTSIRSAIETLDLVTEPAARARLLAILQNDVNRLDRLVTDISNASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LDAELSREHPKALDLGRLLTEVVSLYENQWRPGDAPGSVRVSLSLADPSQPAIILGRETP
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCC
IGQVFRNLIDNARSFSPADGEVRVTLSRTRGGLIAAVEDDGPGMPPENLETIFERFYTSR
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
PKGRAFGGNSGLGLSIARQIVETHGGTVHAENRKDANGAVVGARFVVELPDARE
CCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEEECCCCCC
>Mature Secondary Structure 
ATVIAKPEAIAPEPKRRFTWPRGSRLGRLIVVLNVVALAIVIVGALILNELRNGLVNAR
CCEECCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSLSTQGELIANVIDQSATVGEPEPALDPYTASQIFQLLFIPRSQRARLFDAQGKALAD
HHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHCCCCCCHHHH
SFVVADRVDWKVLPPARKPDQKDDDARTTPDRAAKAKRAQEALANEIAQAMRGRTVAGTR
HHHHCCCCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
IAENGERVVSVSIPIQHVKAVLGVLTLEASDVDEIIAAQRKALLPFIAVAMLAILTSSVL
HHCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHRLIAVPVLRLARAADHVRLQGARAISLPDLSERKDELGDLSRSLEDMTHSLSERMDAI
HHHHHHHHHHHHHHHHHHHEECCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERFAADVAHEIKNPLTSIRSAIETLDLVTEPAARARLLAILQNDVNRLDRLVTDISNASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LDAELSREHPKALDLGRLLTEVVSLYENQWRPGDAPGSVRVSLSLADPSQPAIILGRETP
HHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCEEEEECCCC
IGQVFRNLIDNARSFSPADGEVRVTLSRTRGGLIAAVEDDGPGMPPENLETIFERFYTSR
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCC
PKGRAFGGNSGLGLSIARQIVETHGGTVHAENRKDANGAVVGARFVVELPDARE
CCCCCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]