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The map label for this gene is hrcA

Identifier: 16124408

GI number: 16124408

Start: 161320

End: 162396

Strand: Direct

Name: hrcA

Synonym: CC_0153

Alternate gene names: 16124408

Gene position: 161320-162396 (Clockwise)

Preceding gene: 16124405

Following gene: 16124409

Centisome position: 4.02

GC content: 69.64

Gene sequence:

>1077_bases
ATGACGCAGCTCTTCCCAGGGCCGATCGTCCGTACGCCTGGGCTGGCCGAGCTGGACGCCCGCGCTCGCGACATCTTCCG
GCGCGTCGTGGAGTCGTATCTCGAGACCGGTGAGCCCGTCGGTTCACGCACCATTTCCAAGGGCGGCGTCGCCCTGTCGC
CGGCCTCGATCCGCAATACGATGCAGGACCTGGCCCAGCTGGGCCTGCTGGACGCGCCGCATACCAGCGCCGGTCGTATG
CCGACCCATGCGGGCCTGCGGATGTTCGTCGACGGCTTTCTGGAGGTCGGTGACGTCGCCGAGCAGGAAAAGCGCGCGAT
CGAGGCGCGCCTCGCCGTGAAGGGCCGCTCGTTCGAGGAGGCGCTGGCCGAGGCCTCGTCGATCCTGTCGGGCCTGGCCG
GCGGAGCCGGGATCGTCGTCACGCCCGTTCGCGAAGGCGGGGTCAAGCACGTGGAGTTCGTCCCCCTGGGCGGCGGCCAG
GTGCTGGCGGTGATGGTGTTCGAGGATGGTCAGGTCGAGAACCGCCTGATGCGCCAGGCGCCGGGCGTCACGCCCTCGGC
GCTGCAGGAGGCGTCCAACTTCCTCAACGCCCGCCTGCGCGGCCGCACCCTGACCGAGGCGCGGACCGAGATGGGCGGTG
AGCTGGACGCCGCGCGACGGCAGCTGAACGAGACGGCCGCCCGCCTCGTCGAGGATGGGCTGGCGGCCTGGAGCGGCGGC
GAGGGCGATGCGCGCTCGCTGATCGTGCGCGGCCAGGCCAACCTGCTGGCCGACGCTCGGGCCCGCGAGGACATCGATCG
CGTGCGGCAGCTGTTCGACGATCTGAGCAGAAGGGCCCAGCTGATCGGCCTGCTGGACGACGTGCGCGACGCCGAGGGTG
TTCGCATCTATATCGGGGCCGAAACACGTCTCTTTTCGCTTTCGGGTTCCTCGGTGATCGCGGCGCCCTATATGACGGGG
CGTCAGAAGGTGCTGGGCGCGATCGGCGTGATCGGGCCCGCCCGCTTGAACTACGCTCGGGTCATTCCGTTGGTGGACTA
TACCGCCCGGGTGCTCGGGCGGATGATGGATGGATAA

Upstream 100 bases:

>100_bases
GGTGGCCGCTTATCCTATTGGAAGCCGAACTTGAAAGGGGCCGACCGCTTTTGTTCGCCGACCGGGTCTTCGAAGTCACG
CTTGATCGGAGCGCAGGGAC

Downstream 100 bases:

>100_bases
GGACTTTACCCAATGACCGACGAGCAAACGCCGGCGGAAGAGATGCCGTTCGAAGCCGATGACGCCGCGCAGGAGATCGA
GGCGCTGAAGCTGGAAGTGG

Product: heat-inducible transcription repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MTQLFPGPIVRTPGLAELDARARDIFRRVVESYLETGEPVGSRTISKGGVALSPASIRNTMQDLAQLGLLDAPHTSAGRM
PTHAGLRMFVDGFLEVGDVAEQEKRAIEARLAVKGRSFEEALAEASSILSGLAGGAGIVVTPVREGGVKHVEFVPLGGGQ
VLAVMVFEDGQVENRLMRQAPGVTPSALQEASNFLNARLRGRTLTEARTEMGGELDAARRQLNETAARLVEDGLAAWSGG
EGDARSLIVRGQANLLADARAREDIDRVRQLFDDLSRRAQLIGLLDDVRDAEGVRIYIGAETRLFSLSGSSVIAAPYMTG
RQKVLGAIGVIGPARLNYARVIPLVDYTARVLGRMMDG

Sequences:

>Translated_358_residues
MTQLFPGPIVRTPGLAELDARARDIFRRVVESYLETGEPVGSRTISKGGVALSPASIRNTMQDLAQLGLLDAPHTSAGRM
PTHAGLRMFVDGFLEVGDVAEQEKRAIEARLAVKGRSFEEALAEASSILSGLAGGAGIVVTPVREGGVKHVEFVPLGGGQ
VLAVMVFEDGQVENRLMRQAPGVTPSALQEASNFLNARLRGRTLTEARTEMGGELDAARRQLNETAARLVEDGLAAWSGG
EGDARSLIVRGQANLLADARAREDIDRVRQLFDDLSRRAQLIGLLDDVRDAEGVRIYIGAETRLFSLSGSSVIAAPYMTG
RQKVLGAIGVIGPARLNYARVIPLVDYTARVLGRMMDG
>Mature_357_residues
TQLFPGPIVRTPGLAELDARARDIFRRVVESYLETGEPVGSRTISKGGVALSPASIRNTMQDLAQLGLLDAPHTSAGRMP
THAGLRMFVDGFLEVGDVAEQEKRAIEARLAVKGRSFEEALAEASSILSGLAGGAGIVVTPVREGGVKHVEFVPLGGGQV
LAVMVFEDGQVENRLMRQAPGVTPSALQEASNFLNARLRGRTLTEARTEMGGELDAARRQLNETAARLVEDGLAAWSGGE
GDARSLIVRGQANLLADARAREDIDRVRQLFDDLSRRAQLIGLLDDVRDAEGVRIYIGAETRLFSLSGSSVIAAPYMTGR
QKVLGAIGVIGPARLNYARVIPLVDYTARVLGRMMDG

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons [H]

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01628 HrcA [H]

EC number: NA

Molecular weight: Translated: 38294; Mature: 38163

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQLFPGPIVRTPGLAELDARARDIFRRVVESYLETGEPVGSRTISKGGVALSPASIRNT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECHHHHHHH
MQDLAQLGLLDAPHTSAGRMPTHAGLRMFVDGFLEVGDVAEQEKRAIEARLAVKGRSFEE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ALAEASSILSGLAGGAGIVVTPVREGGVKHVEFVPLGGGQVLAVMVFEDGQVENRLMRQA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHC
PGVTPSALQEASNFLNARLRGRTLTEARTEMGGELDAARRQLNETAARLVEDGLAAWSGG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGDARSLIVRGQANLLADARAREDIDRVRQLFDDLSRRAQLIGLLDDVRDAEGVRIYIGA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
ETRLFSLSGSSVIAAPYMTGRQKVLGAIGVIGPARLNYARVIPLVDYTARVLGRMMDG
CEEEEEECCCCEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQLFPGPIVRTPGLAELDARARDIFRRVVESYLETGEPVGSRTISKGGVALSPASIRNT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEECHHHHHHH
MQDLAQLGLLDAPHTSAGRMPTHAGLRMFVDGFLEVGDVAEQEKRAIEARLAVKGRSFEE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
ALAEASSILSGLAGGAGIVVTPVREGGVKHVEFVPLGGGQVLAVMVFEDGQVENRLMRQA
HHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEEECCCCCEEEEEEECCCCHHHHHHHHC
PGVTPSALQEASNFLNARLRGRTLTEARTEMGGELDAARRQLNETAARLVEDGLAAWSGG
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
EGDARSLIVRGQANLLADARAREDIDRVRQLFDDLSRRAQLIGLLDDVRDAEGVRIYIGA
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
ETRLFSLSGSSVIAAPYMTGRQKVLGAIGVIGPARLNYARVIPLVDYTARVLGRMMDG
CEEEEEECCCCEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8606155 [H]