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The map label for this gene is ggt [H]

Identifier: 16124359

GI number: 16124359

Start: 113409

End: 115160

Strand: Direct

Name: ggt [H]

Synonym: CC_0104

Alternate gene names: 16124359

Gene position: 113409-115160 (Clockwise)

Preceding gene: 16124358

Following gene: 16124361

Centisome position: 2.82

GC content: 69.29

Gene sequence:

>1752_bases
TTGCCCGCTCCGCCCAATCGGCTAGCGTGGCGGAACGATCTCCTGGAGGCCGCCTTGCGCCTGTTCGCTCCCCTCGCCGC
CGCCCTTTCGGCGGCGCTTCTGCTTGTCGCGCCGAGCGTCGAGGCCAAGCCGAGGTCCGCCGCCGCAGCGGTCCGGGCGC
TGGAGGCGGGAGCCGTGGCCTCGCCCGACCAATACGGCGCCCTCGCGGCGCAGGAGGTTCTCAAGGCCGGCGGCAATGCG
GTCGATGCGGCGGTGGCCACCGGCTTCGCCCTGGCCGTCACCTATCCCGAAGCCGGCAATCTGGGCGGGGGCGGGTTCAT
GACCGTCTACATGGACGGCAAGCCCTACTTCCTAGACTACCGCGAGACGGCGCCGGCGGCGGCCAGGGCCGACATGTATC
TGGGTCCCGATGGCGAGCTGGTCGAGGGTCTGTCGCTGTACGGCGGTCTGGCGGCGGGCGTGCCGGGCACGGTGCGCGGC
CTGGCCATGGCCCATCAGCGCTTTGGCAAGCTGCCTTGGGGGCAGGTTCTGGCCCCGGCCATCCGCTATGCGCGGGACGG
CTTCGTCGTCGATGCGCATCTGGCGGGGGTGCTGGCCGACGAGCCGCCGCCTGAGTTCGCCAAGACCAACTTCCGCACCT
ACTTCGCGGCGCACAAGGCCGGGACGCTGTTCAAGCAGCCCGAGCTGGCCGCCACCCTGGAGCGGATCGCCCTGGTCGGC
GACCGGGCGTTCTATGAGGGCAAGACCGCCGACCTGATCGTCGCCCAGATGGCGCGGGGCCCGGTGAAGGGGCTGATCAC
CAAGGCCGACCTTTCGACCTACAAGGCGGCCTGGCGGACGCCGCTGGTCGCTAAGTGGCGCGGCTATGACGTGATCACCG
CCCCGCCGCCCAGCTCGGGCGGGATCGCCCTGATGCAGCTGCTCCTGATGAAGCAGAACCTGGCGCCGATGTTCCAGGGC
GTGGCCCTGAACGATCCGCAGTATGTCCACCTGCTGGCCGAGATCGAAAAGCGCGTCTACGCCGACCGCGCCGAGTATCT
GGGCGATCCGGATTTCGTGAAGGTCCCGGTCTCGAACCTGATCGACCCGGCCTATGTGGCGCGGCGCGCCAAGGAGGTCG
ATCCCGCCAAGCCTTCGGCGACCAAGGCCGTCCAGCCGGGTCTGGAGAAGCACGAGACCACCCACTATTCGATCGTCGAC
CAATGGGGAAACGCCGTCTCCAACACCTACACCCTGAACGGCTCGTTCGGCTCGGGCGTGGTGGTCGAGGGCGCGGGCTT
CATCCTCAACAACGAGATGGACGACTTCTCGGCCAAGCCCGGCGCGCCCAACATGTTCGGCGTGGTCGGCGGGGCGGCCA
ACGCCATCGCGCCCGGCAAGCGCCCCCTGTCCTCGATGACCCCCACGATCCTGACCAAGGACGGCCGGGTGGCCATGGTG
ATCGGCACGCCCGGCGGCTCGCGGATCTTCGCCTGGGTCTTCCAGGTGCTGGCCAATGTCTATGACCATGGTCTGAGCCT
AAAGGCCGCCCAGGCCGCGCCGCGCTTTCACCATCAGCTGTTGCCGCAGAACGTGATCTTCTACGAACGCTCGGGCCCGC
CCTCGGCTGACCTGAAGGCGGCGCTGGAGGCGCGGGGCTACACTTGGACCGAGAGCTTCAGCGGCGATGTCGAGGCGATC
CAGGTGCTGGGCCGCACGCCGGTTCCCGAGCCCGACCCCCGTGCGCGCGGGGTGGGGCTGGTGGTGAAGTAG

Upstream 100 bases:

>100_bases
CCGCGACGGCCCCGAACCCACCCGCTTCGGCGACTGGGAGAAGAAGGGCGTCGCCGTCGATTTCTAGAGGACGGTTCCCC
GGCCTCTGACGCTTCGGCCG

Downstream 100 bases:

>100_bases
CTTGTCACTTGCCCCCACCTGACCTGCTCACGCAGGTCGTCCGCCCCCAAAGGGGGCGGAAGGTGATGCAGCGATCCTTC
TTCCCCCTCCGGGGGAGGAG

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 582

Protein sequence:

>583_residues
MPAPPNRLAWRNDLLEAALRLFAPLAAALSAALLLVAPSVEAKPRSAAAAVRALEAGAVASPDQYGALAAQEVLKAGGNA
VDAAVATGFALAVTYPEAGNLGGGGFMTVYMDGKPYFLDYRETAPAAARADMYLGPDGELVEGLSLYGGLAAGVPGTVRG
LAMAHQRFGKLPWGQVLAPAIRYARDGFVVDAHLAGVLADEPPPEFAKTNFRTYFAAHKAGTLFKQPELAATLERIALVG
DRAFYEGKTADLIVAQMARGPVKGLITKADLSTYKAAWRTPLVAKWRGYDVITAPPPSSGGIALMQLLLMKQNLAPMFQG
VALNDPQYVHLLAEIEKRVYADRAEYLGDPDFVKVPVSNLIDPAYVARRAKEVDPAKPSATKAVQPGLEKHETTHYSIVD
QWGNAVSNTYTLNGSFGSGVVVEGAGFILNNEMDDFSAKPGAPNMFGVVGGAANAIAPGKRPLSSMTPTILTKDGRVAMV
IGTPGGSRIFAWVFQVLANVYDHGLSLKAAQAAPRFHHQLLPQNVIFYERSGPPSADLKAALEARGYTWTESFSGDVEAI
QVLGRTPVPEPDPRARGVGLVVK

Sequences:

>Translated_583_residues
MPAPPNRLAWRNDLLEAALRLFAPLAAALSAALLLVAPSVEAKPRSAAAAVRALEAGAVASPDQYGALAAQEVLKAGGNA
VDAAVATGFALAVTYPEAGNLGGGGFMTVYMDGKPYFLDYRETAPAAARADMYLGPDGELVEGLSLYGGLAAGVPGTVRG
LAMAHQRFGKLPWGQVLAPAIRYARDGFVVDAHLAGVLADEPPPEFAKTNFRTYFAAHKAGTLFKQPELAATLERIALVG
DRAFYEGKTADLIVAQMARGPVKGLITKADLSTYKAAWRTPLVAKWRGYDVITAPPPSSGGIALMQLLLMKQNLAPMFQG
VALNDPQYVHLLAEIEKRVYADRAEYLGDPDFVKVPVSNLIDPAYVARRAKEVDPAKPSATKAVQPGLEKHETTHYSIVD
QWGNAVSNTYTLNGSFGSGVVVEGAGFILNNEMDDFSAKPGAPNMFGVVGGAANAIAPGKRPLSSMTPTILTKDGRVAMV
IGTPGGSRIFAWVFQVLANVYDHGLSLKAAQAAPRFHHQLLPQNVIFYERSGPPSADLKAALEARGYTWTESFSGDVEAI
QVLGRTPVPEPDPRARGVGLVVK
>Mature_582_residues
PAPPNRLAWRNDLLEAALRLFAPLAAALSAALLLVAPSVEAKPRSAAAAVRALEAGAVASPDQYGALAAQEVLKAGGNAV
DAAVATGFALAVTYPEAGNLGGGGFMTVYMDGKPYFLDYRETAPAAARADMYLGPDGELVEGLSLYGGLAAGVPGTVRGL
AMAHQRFGKLPWGQVLAPAIRYARDGFVVDAHLAGVLADEPPPEFAKTNFRTYFAAHKAGTLFKQPELAATLERIALVGD
RAFYEGKTADLIVAQMARGPVKGLITKADLSTYKAAWRTPLVAKWRGYDVITAPPPSSGGIALMQLLLMKQNLAPMFQGV
ALNDPQYVHLLAEIEKRVYADRAEYLGDPDFVKVPVSNLIDPAYVARRAKEVDPAKPSATKAVQPGLEKHETTHYSIVDQ
WGNAVSNTYTLNGSFGSGVVVEGAGFILNNEMDDFSAKPGAPNMFGVVGGAANAIAPGKRPLSSMTPTILTKDGRVAMVI
GTPGGSRIFAWVFQVLANVYDHGLSLKAAQAAPRFHHQLLPQNVIFYERSGPPSADLKAALEARGYTWTESFSGDVEAIQ
VLGRTPVPEPDPRARGVGLVVK

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=529, Percent_Identity=34.4045368620038, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI73915090, Length=529, Percent_Identity=34.4045368620038, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI73915096, Length=529, Percent_Identity=34.4045368620038, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI73915094, Length=529, Percent_Identity=34.4045368620038, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI113429324, Length=517, Percent_Identity=33.2688588007737, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI113429326, Length=521, Percent_Identity=32.6295585412668, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI109148539, Length=532, Percent_Identity=30.8270676691729, Blast_Score=163, Evalue=4e-40,
Organism=Homo sapiens, GI153266885, Length=550, Percent_Identity=28, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI153266901, Length=551, Percent_Identity=27.9491833030853, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI153266907, Length=547, Percent_Identity=26.508226691042, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI30581157, Length=172, Percent_Identity=45.3488372093023, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI30581155, Length=172, Percent_Identity=45.3488372093023, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI218505805, Length=175, Percent_Identity=39.4285714285714, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI310124095, Length=175, Percent_Identity=36.5714285714286, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1789856, Length=506, Percent_Identity=47.2332015810277, Blast_Score=426, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI72000294, Length=553, Percent_Identity=33.2730560578662, Blast_Score=242, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI212646519, Length=553, Percent_Identity=33.2730560578662, Blast_Score=242, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI17542894, Length=503, Percent_Identity=34.3936381709742, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193208245, Length=491, Percent_Identity=34.2158859470468, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI193208247, Length=491, Percent_Identity=34.2158859470468, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI17506189, Length=508, Percent_Identity=33.0708661417323, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17564448, Length=431, Percent_Identity=25.5220417633411, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI72001497, Length=401, Percent_Identity=22.9426433915212, Blast_Score=78, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323330, Length=568, Percent_Identity=30.1056338028169, Blast_Score=143, Evalue=6e-35,
Organism=Drosophila melanogaster, GI161077496, Length=560, Percent_Identity=33.2142857142857, Blast_Score=232, Evalue=6e-61,
Organism=Drosophila melanogaster, GI18859893, Length=551, Percent_Identity=33.2123411978221, Blast_Score=226, Evalue=5e-59,
Organism=Drosophila melanogaster, GI45551474, Length=512, Percent_Identity=32.2265625, Blast_Score=199, Evalue=5e-51,
Organism=Drosophila melanogaster, GI24642670, Length=512, Percent_Identity=32.2265625, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI24642666, Length=512, Percent_Identity=32.2265625, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI161077880, Length=512, Percent_Identity=32.2265625, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI161077878, Length=512, Percent_Identity=32.2265625, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI18859741, Length=491, Percent_Identity=31.5682281059063, Blast_Score=187, Evalue=2e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 61694; Mature: 61563

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPPNRLAWRNDLLEAALRLFAPLAAALSAALLLVAPSVEAKPRSAAAAVRALEAGAVA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCC
SPDQYGALAAQEVLKAGGNAVDAAVATGFALAVTYPEAGNLGGGGFMTVYMDGKPYFLDY
CCHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECCCEEEEEC
RETAPAAARADMYLGPDGELVEGLSLYGGLAAGVPGTVRGLAMAHQRFGKLPWGQVLAPA
CCCCCCHHCCCEEECCCCHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
IRYARDGFVVDAHLAGVLADEPPPEFAKTNFRTYFAAHKAGTLFKQPELAATLERIALVG
HHHHCCCEEEEHHHHHHHCCCCCCHHHHCCCHHEEEHHHCCCCCCCCHHHHHHHHHHHHC
DRAFYEGKTADLIVAQMARGPVKGLITKADLSTYKAAWRTPLVAKWRGYDVITAPPPSSG
CHHHCCCCCHHHHHHHHHCCCHHHEEEHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCC
GIALMQLLLMKQNLAPMFQGVALNDPQYVHLLAEIEKRVYADRAEYLGDPDFVKVPVSNL
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHC
IDPAYVARRAKEVDPAKPSATKAVQPGLEKHETTHYSIVDQWGNAVSNTYTLNGSFGSGV
CCHHHHHHHHHCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHCCHHCCEEEECCCCCCCE
VVEGAGFILNNEMDDFSAKPGAPNMFGVVGGAANAIAPGKRPLSSMTPTILTKDGRVAMV
EEECCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCEEEECCCCEEEE
IGTPGGSRIFAWVFQVLANVYDHGLSLKAAQAAPRFHHQLLPQNVIFYERSGPPSADLKA
EECCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCHHHHHHHCCCCEEEEECCCCCCHHHHH
ALEARGYTWTESFSGDVEAIQVLGRTPVPEPDPRARGVGLVVK
HHHHCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEC
>Mature Secondary Structure 
PAPPNRLAWRNDLLEAALRLFAPLAAALSAALLLVAPSVEAKPRSAAAAVRALEAGAVA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCCCC
SPDQYGALAAQEVLKAGGNAVDAAVATGFALAVTYPEAGNLGGGGFMTVYMDGKPYFLDY
CCHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEEECCCCCCCCCCCEEEEEECCCEEEEEC
RETAPAAARADMYLGPDGELVEGLSLYGGLAAGVPGTVRGLAMAHQRFGKLPWGQVLAPA
CCCCCCHHCCCEEECCCCHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
IRYARDGFVVDAHLAGVLADEPPPEFAKTNFRTYFAAHKAGTLFKQPELAATLERIALVG
HHHHCCCEEEEHHHHHHHCCCCCCHHHHCCCHHEEEHHHCCCCCCCCHHHHHHHHHHHHC
DRAFYEGKTADLIVAQMARGPVKGLITKADLSTYKAAWRTPLVAKWRGYDVITAPPPSSG
CHHHCCCCCHHHHHHHHHCCCHHHEEEHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCC
GIALMQLLLMKQNLAPMFQGVALNDPQYVHLLAEIEKRVYADRAEYLGDPDFVKVPVSNL
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHC
IDPAYVARRAKEVDPAKPSATKAVQPGLEKHETTHYSIVDQWGNAVSNTYTLNGSFGSGV
CCHHHHHHHHHCCCCCCCCCHHHHCCCHHHHCCCHHHHHHHHCCHHCCEEEECCCCCCCE
VVEGAGFILNNEMDDFSAKPGAPNMFGVVGGAANAIAPGKRPLSSMTPTILTKDGRVAMV
EEECCCEEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHCCCEEEECCCCEEEE
IGTPGGSRIFAWVFQVLANVYDHGLSLKAAQAAPRFHHQLLPQNVIFYERSGPPSADLKA
EECCCCHHHHHHHHHHHHHHHHCCCCEEHHHHCHHHHHHHCCCCEEEEECCCCCCHHHHH
ALEARGYTWTESFSGDVEAIQVLGRTPVPEPDPRARGVGLVVK
HHHHCCCEECCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]