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The map label for this gene is dnaQ [H]

Identifier: 16124261

GI number: 16124261

Start: 3190

End: 3903

Strand: Direct

Name: dnaQ [H]

Synonym: CC_0005

Alternate gene names: 16124261

Gene position: 3190-3903 (Clockwise)

Preceding gene: 16124260

Following gene: 16124262

Centisome position: 0.08

GC content: 64.15

Gene sequence:

>714_bases
ATGGCCCGCGAGATCATCCTCGATACCGAAACCACCGGCTTTGACCCAAAGACCGGTGACCGCCTGGTCGAAATCGGCTG
CATCGAAGTGGTCGATTTCATGCCGACCGGCCGCTCGTTCCACGAGTACTGCGACCCGCTGCGCGACATGCCCGCCGAGG
CTGAGAAGGTTCATGGCCTGTCCAGCGCCTTCCTGACCGGCAAGCCGAAATTCCACGAGATCGCCGATCGCTTCCTGGAT
TTTGTCGGCGACAGCGTCGTGGTGGCCCACAACGCCGCCTTCGACCGTCAGTTCGTCAATTTCGAGCTGGAGAAATGCGG
CAAGGCCCCGATCCACGAGGAGCGCTGGGTCGACACGCTGGCCATGGCCAAGAAGCGCTTCCCGGGCATGTACAACTCGC
TCGACGCGCTCTGTAAGCGGTTCAAGATCAGCCTGGAGAGCCGCGACAAGCACGGCGCCCTGATCGACGCCCACCTGCTG
GCCGAGGTCTATCTGGAACTGCAGGGCGGCAAGGAACGCGCCCTTGAACTGACCCATTCGACAGGGGCCATGGCGGTCTC
CACCGCGATCCAGGGCGTCTATGCCGCACGGTCACGTCCCCTGGCGCCGCGCTCCACGGACGCCGAGCGCGAGATCCACG
CCGCCTGGGTTCGCAAGAACCTCAAGGACAAGGCGCTCTGGATCCAGTTCGGCGTGGTCGCTGCCGAAGCCTAG

Upstream 100 bases:

>100_bases
GGCCTAGACCACGCGCGCCGCCAGGTCCGCGACCTTCTGACTCTGTTGAGAACCGCCCGCTCGGCTTGAAGCCGACCGCG
AACGGCTTCATGGAAGGGCC

Downstream 100 bases:

>100_bases
GCGCCCTCGCCGCCTGGCGCCGACGATGGCTCCGGCCCGACCGGTCTGTACAAGTTAGAGGGACTCCCCAACGCGACAGC
CCTCTCTATAACTGCGCCGG

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MAREIILDTETTGFDPKTGDRLVEIGCIEVVDFMPTGRSFHEYCDPLRDMPAEAEKVHGLSSAFLTGKPKFHEIADRFLD
FVGDSVVVAHNAAFDRQFVNFELEKCGKAPIHEERWVDTLAMAKKRFPGMYNSLDALCKRFKISLESRDKHGALIDAHLL
AEVYLELQGGKERALELTHSTGAMAVSTAIQGVYAARSRPLAPRSTDAEREIHAAWVRKNLKDKALWIQFGVVAAEA

Sequences:

>Translated_237_residues
MAREIILDTETTGFDPKTGDRLVEIGCIEVVDFMPTGRSFHEYCDPLRDMPAEAEKVHGLSSAFLTGKPKFHEIADRFLD
FVGDSVVVAHNAAFDRQFVNFELEKCGKAPIHEERWVDTLAMAKKRFPGMYNSLDALCKRFKISLESRDKHGALIDAHLL
AEVYLELQGGKERALELTHSTGAMAVSTAIQGVYAARSRPLAPRSTDAEREIHAAWVRKNLKDKALWIQFGVVAAEA
>Mature_236_residues
AREIILDTETTGFDPKTGDRLVEIGCIEVVDFMPTGRSFHEYCDPLRDMPAEAEKVHGLSSAFLTGKPKFHEIADRFLDF
VGDSVVVAHNAAFDRQFVNFELEKCGKAPIHEERWVDTLAMAKKRFPGMYNSLDALCKRFKISLESRDKHGALIDAHLLA
EVYLELQGGKERALELTHSTGAMAVSTAIQGVYAARSRPLAPRSTDAEREIHAAWVRKNLKDKALWIQFGVVAAEA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=223, Percent_Identity=39.9103139013453, Blast_Score=154, Evalue=5e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26459; Mature: 26328

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREIILDTETTGFDPKTGDRLVEIGCIEVVDFMPTGRSFHEYCDPLRDMPAEAEKVHGL
CCCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHCC
SSAFLTGKPKFHEIADRFLDFVGDSVVVAHNAAFDRQFVNFELEKCGKAPIHEERWVDTL
HHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHCEEHHHCCCCCCCHHHHHHHH
AMAKKRFPGMYNSLDALCKRFKISLESRDKHGALIDAHLLAEVYLELQGGKERALELTHS
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHEEECCC
TGAMAVSTAIQGVYAARSRPLAPRSTDAEREIHAAWVRKNLKDKALWIQFGVVAAEA
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECEEEECC
>Mature Secondary Structure 
AREIILDTETTGFDPKTGDRLVEIGCIEVVDFMPTGRSFHEYCDPLRDMPAEAEKVHGL
CCEEEEECCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHCC
SSAFLTGKPKFHEIADRFLDFVGDSVVVAHNAAFDRQFVNFELEKCGKAPIHEERWVDTL
HHHHHCCCCCHHHHHHHHHHHHCCCEEEEECCHHHHHHHCEEHHHCCCCCCCHHHHHHHH
AMAKKRFPGMYNSLDALCKRFKISLESRDKHGALIDAHLLAEVYLELQGGKERALELTHS
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHEEECCC
TGAMAVSTAIQGVYAARSRPLAPRSTDAEREIHAAWVRKNLKDKALWIQFGVVAAEA
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCHHEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA