Click here to switch to the map view.

The map label for this gene is fimB [C]

Identifier: 13488300

GI number: 13488300

Start: 284594

End: 285544

Strand: Direct

Name: fimB [C]

Synonym: mlr9323

Alternate gene names: 13488300

Gene position: 284594-285544 (Clockwise)

Preceding gene: 13488299

Following gene: 13488301

Centisome position: 80.87

GC content: 54.05

Gene sequence:

>951_bases
ATGTGCAATGAAACCTGGCAATCTAGAGCCGAAGAATATATCGACGATAGCCGTCGTCTCGGCTACGCCTTGACCACCAC
AAGTGCCTACCTGCTGTCATTTGCTCGGTTTGTCGATCAACGCGGACACTCCGGAGCGCTGACATCCGACATCATTCTTG
ATTGGGCGCAAAGCACTGACAGCAAGAAGCCAACTACATGGACGAAGCGTTTAATCAACATTCGTCGTTTTATAAGCCAT
TGCTCACGAGTGGACGGCAAATCTGAAGTACCTCGGGTTGATGTCTTTGGTCGACCAAAGGGAAGACCAACACCTCACAT
CTATACTGAACTGGAAATCTCCGAACTGCTGGCTGCGGCCAGGGAACTACCCGGCACGTTGCCATCGGCAACTTATGAGA
CGCTGTTCGGTCTTCTGGCCTCGACAGGGTTACGCCTTTCAGAAGCGCTTCATCTACGTTGTTCCGATGTCGATCTGAGG
TCAGGACGCCTGATAGTGCGTCAGGGAAAGCTGGGCAAATCGCGACTGGTTCCTCTGCACGCTACAGTGTGCGAGGTTTT
GTCCCGATATCTTGGTGTCAGGCAACAGTTGCCACTGACCTCGGAGAGCTACTTCTTCGTCTCCCAGACCGGGGGTCTTC
TTCCACGCCGAACAGTCGAAGGCGTGTTCATCAGATTGCGCACGAAATTGGGGTGGGCGCCTCGTGGCAACTGGCGGGCT
CCGCGAATTCATGACTTGAGGCATACATTCATATGCCGGCGAGTGACCCAATGGCACAAGGAAGGAGCCGACATCGATAA
CGCAATGCTATACGTTTCGACCTACGTCGGCCACGTGGCAGTGACATACACCTATTGGTACCTTACCGGCATTCCTGAAC
TCATGACGGTTGTTGGCCAGCGCTTCGAGGCGTTTGCTGAGAGTGCGCGGGGGGCCGAAAATGCCGAATAG

Upstream 100 bases:

>100_bases
TCCTTCGACATCGGAGCCTGAATACATCGATGGTGTATTTGAAGGTTGACGCGGATCGCCTAGCCGCAGTCGCACTCCCG
TGGCCGGGGAGGGTTGTCTG

Downstream 100 bases:

>100_bases
AAAAACGCACCCTTCCTTCGCGGTCTTGCTACAGCGGTACTTCACCGAACATCTTACCAATCAGCGCGCGGTCAGTCCGC
GGACTATTGCGGCTTATCGG

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MCNETWQSRAEEYIDDSRRLGYALTTTSAYLLSFARFVDQRGHSGALTSDIILDWAQSTDSKKPTTWTKRLINIRRFISH
CSRVDGKSEVPRVDVFGRPKGRPTPHIYTELEISELLAAARELPGTLPSATYETLFGLLASTGLRLSEALHLRCSDVDLR
SGRLIVRQGKLGKSRLVPLHATVCEVLSRYLGVRQQLPLTSESYFFVSQTGGLLPRRTVEGVFIRLRTKLGWAPRGNWRA
PRIHDLRHTFICRRVTQWHKEGADIDNAMLYVSTYVGHVAVTYTYWYLTGIPELMTVVGQRFEAFAESARGAENAE

Sequences:

>Translated_316_residues
MCNETWQSRAEEYIDDSRRLGYALTTTSAYLLSFARFVDQRGHSGALTSDIILDWAQSTDSKKPTTWTKRLINIRRFISH
CSRVDGKSEVPRVDVFGRPKGRPTPHIYTELEISELLAAARELPGTLPSATYETLFGLLASTGLRLSEALHLRCSDVDLR
SGRLIVRQGKLGKSRLVPLHATVCEVLSRYLGVRQQLPLTSESYFFVSQTGGLLPRRTVEGVFIRLRTKLGWAPRGNWRA
PRIHDLRHTFICRRVTQWHKEGADIDNAMLYVSTYVGHVAVTYTYWYLTGIPELMTVVGQRFEAFAESARGAENAE
>Mature_316_residues
MCNETWQSRAEEYIDDSRRLGYALTTTSAYLLSFARFVDQRGHSGALTSDIILDWAQSTDSKKPTTWTKRLINIRRFISH
CSRVDGKSEVPRVDVFGRPKGRPTPHIYTELEISELLAAARELPGTLPSATYETLFGLLASTGLRLSEALHLRCSDVDLR
SGRLIVRQGKLGKSRLVPLHATVCEVLSRYLGVRQQLPLTSESYFFVSQTGGLLPRRTVEGVFIRLRTKLGWAPRGNWRA
PRIHDLRHTFICRRVTQWHKEGADIDNAMLYVSTYVGHVAVTYTYWYLTGIPELMTVVGQRFEAFAESARGAENAE

Specific function: Fimb Is One Of The 2 Regulatory Proteins Which Control The Phase Variation Of Type 1 Fimbriae In E. coli. These Proteins Mediate The Periodic Inversion Of A 300bp DNA Segment That Harbors The Promoter For The Fimbrial Structural Gene, Fima. Fimb Switches

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35792; Mature: 35792

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNETWQSRAEEYIDDSRRLGYALTTTSAYLLSFARFVDQRGHSGALTSDIILDWAQSTD
CCCHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
SKKPTTWTKRLINIRRFISHCSRVDGKSEVPRVDVFGRPKGRPTPHIYTELEISELLAAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHH
RELPGTLPSATYETLFGLLASTGLRLSEALHLRCSDVDLRSGRLIVRQGKLGKSRLVPLH
HHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCCEEEEEECCCCCCCCCCHH
ATVCEVLSRYLGVRQQLPLTSESYFFVSQTGGLLPRRTVEGVFIRLRTKLGWAPRGNWRA
HHHHHHHHHHHCHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHEEEEHHCCCCCCCCCCC
PRIHDLRHTFICRRVTQWHKEGADIDNAMLYVSTYVGHVAVTYTYWYLTGIPELMTVVGQ
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
RFEAFAESARGAENAE
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MCNETWQSRAEEYIDDSRRLGYALTTTSAYLLSFARFVDQRGHSGALTSDIILDWAQSTD
CCCHHHHHHHHHHHHHHHHCCEEHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCC
SKKPTTWTKRLINIRRFISHCSRVDGKSEVPRVDVFGRPKGRPTPHIYTELEISELLAAA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHH
RELPGTLPSATYETLFGLLASTGLRLSEALHLRCSDVDLRSGRLIVRQGKLGKSRLVPLH
HHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHEEECCCCCCCCEEEEEECCCCCCCCCCHH
ATVCEVLSRYLGVRQQLPLTSESYFFVSQTGGLLPRRTVEGVFIRLRTKLGWAPRGNWRA
HHHHHHHHHHHCHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHEEEEHHCCCCCCCCCCC
PRIHDLRHTFICRRVTQWHKEGADIDNAMLYVSTYVGHVAVTYTYWYLTGIPELMTVVGQ
CCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
RFEAFAESARGAENAE
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]