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The map label for this gene is prsA [H]

Identifier: 13488227

GI number: 13488227

Start: 139518

End: 140600

Strand: Direct

Name: prsA [H]

Synonym: mlr9159

Alternate gene names: 13488227

Gene position: 139518-140600 (Clockwise)

Preceding gene: 13488226

Following gene: 13488228

Centisome position: 39.65

GC content: 59.56

Gene sequence:

>1083_bases
ATGCCCTTCAAACGCGTCTACGCCGCCGCCCTTCTGTCCTTGCCGCTGACGACCGTCCCCCTCACGGCCCTATCCTCGGA
CGACGACCCCATCGTTCTTTCGATTGGCCACGAACGATGGACCGCCTCCCAGTTCCAGCGCCTCATGTTGGATACTCCGC
CGCAGGTGAAGGAGGAGGCGGCTGCCGAACCTGACGTATTCGCCAAGCGCTATGCCGACATGCACCTGCTCGCGCAGCTG
GCCGAATCCCGCCACCTGGACCAGGATGCGGACATTCGTCAGCGGCTCGCATGGGTCCGCGAGGGGGTCATGGCGAATGC
CGCCAAGAACGACCTGTATCAGCGCACGCAAGTCGGGAATGAAGAAGTGAGGCGCTACTATGACGAGCATGTCAGTGACT
TCGTGGACTATACGCTACAGCATCTGGTGATCGGCTACCACGGCGCCGAGAGCGCCAGGAACGTCGGGCGAAAGGATATG
GCAGAGGACGACGCTCGGGCGGAAGCCGAGCAGCTGCGAAAGCAGCTCCTGGAGGGGGAAAACTTTGCCGAACTCGTTCA
ATGCTATTCGTATGACGACGACTCTAAGAGCGATGGCGGTCTGTTGCCGGAAACGGCGTCGCGCAATCTGCTGCCGGAGA
TCGCCCAGGGCATCGCCGATCTCAAGGAGAACGAGATCTCCCACCCTATCAAGACGCTCTATGGCTACCACTTGGTTCGT
GTCATCAAGCGTTCCGACAACAGTTTCGAAGATGCACGCCGGCACATCGTGAACCTGCTAAAGAGCCAGATAGTCGATCA
GCAAATCGACGCCATAATTTGGCGTCGACGTCTTTCAGATGTGTTTGCAGCTGCGCATATTCCTTGGCATGGAGCGCGAA
CAGCTCCCGCGCCAAATCCGGTAGCGTCTTATCTGCCGCGATACGCTCGAGCAGCGGTTCGATCTTGCACATCCCCTTGG
CAGCGATCAGCCCGTATTCTGCCGCATAGCCGCGGATCGCATTGGCGAGCTGTGTGCGATTGCGGATCAGCCGGTCGCGC
AGGCCAACCAGCATTAATGCCGCCTGTTGTTCAGCGGTCTTGA

Upstream 100 bases:

>100_bases
GCGGAGACAAAAAGGCCATGGAATAATGCGCCGACGCACCGCCGACGACGGGCGGTGCGCCGGATTTTGTAATCAGAATC
TACACGCATAAGGTCATTTT

Downstream 100 bases:

>100_bases
CCGGCACAAACCGCATCGTCGGCCGGCTCATCGCTTCGCACAGCGCTTCGGCATCGGCCGCATCGTTCTTGCCGCGCTTG
ACGTACGGTTTGACATATTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MPFKRVYAAALLSLPLTTVPLTALSSDDDPIVLSIGHERWTASQFQRLMLDTPPQVKEEAAAEPDVFAKRYADMHLLAQL
AESRHLDQDADIRQRLAWVREGVMANAAKNDLYQRTQVGNEEVRRYYDEHVSDFVDYTLQHLVIGYHGAESARNVGRKDM
AEDDARAEAEQLRKQLLEGENFAELVQCYSYDDDSKSDGGLLPETASRNLLPEIAQGIADLKENEISHPIKTLYGYHLVR
VIKRSDNSFEDARRHIVNLLKSQIVDQQIDAIIWRRRLSDVFAAAHIPWHGARTAPAPNPVASYLPRYARAAVRSCTSPW
QRSARILPHSRGSHWRAVCDCGSAGRAGQPALMPPVVQRS

Sequences:

>Translated_360_residues
MPFKRVYAAALLSLPLTTVPLTALSSDDDPIVLSIGHERWTASQFQRLMLDTPPQVKEEAAAEPDVFAKRYADMHLLAQL
AESRHLDQDADIRQRLAWVREGVMANAAKNDLYQRTQVGNEEVRRYYDEHVSDFVDYTLQHLVIGYHGAESARNVGRKDM
AEDDARAEAEQLRKQLLEGENFAELVQCYSYDDDSKSDGGLLPETASRNLLPEIAQGIADLKENEISHPIKTLYGYHLVR
VIKRSDNSFEDARRHIVNLLKSQIVDQQIDAIIWRRRLSDVFAAAHIPWHGARTAPAPNPVASYLPRYARAAVRSCTSPW
QRSARILPHSRGSHWRAVCDCGSAGRAGQPALMPPVVQRS
>Mature_359_residues
PFKRVYAAALLSLPLTTVPLTALSSDDDPIVLSIGHERWTASQFQRLMLDTPPQVKEEAAAEPDVFAKRYADMHLLAQLA
ESRHLDQDADIRQRLAWVREGVMANAAKNDLYQRTQVGNEEVRRYYDEHVSDFVDYTLQHLVIGYHGAESARNVGRKDMA
EDDARAEAEQLRKQLLEGENFAELVQCYSYDDDSKSDGGLLPETASRNLLPEIAQGIADLKENEISHPIKTLYGYHLVRV
IKRSDNSFEDARRHIVNLLKSQIVDQQIDAIIWRRRLSDVFAAAHIPWHGARTAPAPNPVASYLPRYARAAVRSCTSPWQ
RSARILPHSRGSHWRAVCDCGSAGRAGQPALMPPVVQRS

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 40537; Mature: 40406

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFKRVYAAALLSLPLTTVPLTALSSDDDPIVLSIGHERWTASQFQRLMLDTPPQVKEEA
CCHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHH
AAEPDVFAKRYADMHLLAQLAESRHLDQDADIRQRLAWVREGVMANAAKNDLYQRTQVGN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EEVRRYYDEHVSDFVDYTLQHLVIGYHGAESARNVGRKDMAEDDARAEAEQLRKQLLEGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCC
NFAELVQCYSYDDDSKSDGGLLPETASRNLLPEIAQGIADLKENEISHPIKTLYGYHLVR
CHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIKRSDNSFEDARRHIVNLLKSQIVDQQIDAIIWRRRLSDVFAAAHIPWHGARTAPAPNP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
VASYLPRYARAAVRSCTSPWQRSARILPHSRGSHWRAVCDCGSAGRAGQPALMPPVVQRS
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
PFKRVYAAALLSLPLTTVPLTALSSDDDPIVLSIGHERWTASQFQRLMLDTPPQVKEEA
CHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHH
AAEPDVFAKRYADMHLLAQLAESRHLDQDADIRQRLAWVREGVMANAAKNDLYQRTQVGN
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EEVRRYYDEHVSDFVDYTLQHLVIGYHGAESARNVGRKDMAEDDARAEAEQLRKQLLEGE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCC
NFAELVQCYSYDDDSKSDGGLLPETASRNLLPEIAQGIADLKENEISHPIKTLYGYHLVR
CHHHHHHHHCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VIKRSDNSFEDARRHIVNLLKSQIVDQQIDAIIWRRRLSDVFAAAHIPWHGARTAPAPNP
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
VASYLPRYARAAVRSCTSPWQRSARILPHSRGSHWRAVCDCGSAGRAGQPALMPPVVQRS
HHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]