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The map label for this gene is 13488191

Identifier: 13488191

GI number: 13488191

Start: 29217

End: 31226

Strand: Direct

Name: 13488191

Synonym: mlr9030

Alternate gene names: NA

Gene position: 29217-31226 (Clockwise)

Preceding gene: 13488190

Following gene: 13488192

Centisome position: 8.3

GC content: 58.06

Gene sequence:

>2010_bases
ATGTGGAAGGTTGGAGTTGATGTCGGAGGCACCTTTACCGATCTGTTCGCGGTTAACACTTTTACGGGAGAGGAGCGAAC
CGGCAAGGTTCTGACAACGCCCGAAGAGCGGTCTAAGGGCGTGCTCAACGCGATCGCCAATGCTGAGCTTAAGCCAAACG
AGATTTCTCTACTCGTTCACGGAACCACGACTGCAACAAACGCACTTATCGAGCGTAGCTTCCCTGATGCCGCGATGATT
ACGACCGAAGGTTTCCGGGACGTCCTGGAAATCGGCCGGATGCATCGCGAGCACCTTTATCGGCCGTATCAAACGAAGCC
GGCTCCACTGATCAGAAGGCGCTATCGATACGCGATAGCCGAACGAACCAATGCAAAGGGCGAGGTCGAAGAGGACATCG
ACGCCGCACAGCTCAAGCCGATCATCGCCTCGATCTCTGAAGCAGGCATTGGTTCGGTAGCCGTCTGTCTCATCAATTCG
TACGCCAATCCGGCAAATGAGCGGAAGGTTGCGAAGATCCTATCGGAGGCGCTCCCGAATATTCGTGTGACGACTTCTGC
TGACGTAAAGCCCGTCTTCCGGGAGCACACGCGTTTCACGCTAGCTTCAATCCGCGCAACCATTCTACCAGTAATGGCCG
ATTACTTCGAGCGGCTACAGGCTCGCCTACTTGAGGGTGGGTTCTCCGGCAACCTCATGATCCTCAAGAGCAACGGCGGG
ATGATGGGTGTCGACCAAGCCCGGCTGCGCGTTGAGGAGCTTGTGGAATCCGGTCCTGCTGGTGGTGTCGGGTACGCCAC
CGAGATAGCGCGCACGGCTGGTTTCCCGAACATTATTCACACCGACATGGGCGGAACCAGTTTCGACGCGTCCATCATCG
AGGACGGCCAGGGCCTCATCACTCGGGAGTACGAGATCGAATTCGATATGCCCGTCGCGGTTCCAATGCTGGACATTCGA
TCGATTGGTGCCGGTGGCGGTTCTGTCGGATGGGTTGATAGTGGCGGTTCGCTCAGGGTCGGCCCCATGTCGGCAGGTTC
TGTGCCAGGTCCAGCTTGCTATGGACGCGGAGGTACGAGACCTGCGATTACCGACGCCAACCTAGTCCTTGGCCGGATCA
GTCCAGATCTCTCAGGAAAGTTCAAGCTGGACGTTCAAGCTGCCCGCGACGCGATTGAAACGATCGCAACCAAGCTCAAT
CTTACTATCGAGCAGTGTGCTGAGGGTATGATCCGGATCGCGACAGAAGCGATGGCGCAGGCCGTGAAGCTCGTGTTGGC
GTCGCGTGGTCGCGATCCGCGTGACTATTGCTTTGCCAGCTTTGGTGGGGCTGGCCCCTTGCACGCTTGCGCAGTTGCGG
AAGCGCTCGGCACGCCCACTGTCATTGTTCCACGGTATTCCGGCGTAGCATCCGCATACGGGGCTCTGCGTCTCGCGATC
AAACACGACGAAGAGGTGTTTCACTACGCGCCGCTGACGGCAGAGGAACTCGATCGGGTTGGTGTGAAACTGCAGTCGCT
TGGCGAAGCCGCCGTCGATGCGCTGGTCGCCCAGGGCGCGAAGGCCGAGGATTTAAGGGTCAGTTTCGTGATGCGGATGC
GGTACGCGGGGCAGACATTCGAGGTCGACGTTGTTCAAGATCGCGGCGCAATAGACGATCGCGATGTTCAACAGCTGGCC
TCGGCATTTCACGAAGCGCACATGCGCGAATTCGGCGTGAGATCTGACGATTTTCCGGTAGAGATTGTGGCCTTGGCAGT
AACTGCCGAAGCGCCTTCGCCCGCCGGCCCCCTGGAATCCGAGCAGAATTCGCAACTTGCTCCTTCACAGCAGAAAGGTC
GCAAGGTGTGGTTTGGCGATTGGACCGAAGCTCTCGTCCATGATGTCGCAGGTGCTCAGTTCGTGAGCGGTCCCGCTCTC
ATTGAGGATCCGCATACCAGCATTGTCATTCCTCCGGGTTGGGCCGCTCGGTTTGACTCAGCTCGAAACTGCATTCTGGA
GAGGGCATGA

Upstream 100 bases:

>100_bases
GAGAGTTTTCTTGACGCTAGCGGACAATCGCGAAAATTGGGATTGACAGGCGCCATATTTTGACGGCAAATCCTTGATCA
ACGATCAAAGGGGAACGTCA

Downstream 100 bases:

>100_bases
TGGCTAATCCAATCGATCCTATCACGTTTGAAGTTCTGCGTAACACGTTTGAACACGTCTGCCGCCGGATGACGGTTATC
CTCCAAAAGTCCTCCTTCTC

Product: hydantoinase

Products: ADP; phosphate; N-carbamoylsarcosine

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MWKVGVDVGGTFTDLFAVNTFTGEERTGKVLTTPEERSKGVLNAIANAELKPNEISLLVHGTTTATNALIERSFPDAAMI
TTEGFRDVLEIGRMHREHLYRPYQTKPAPLIRRRYRYAIAERTNAKGEVEEDIDAAQLKPIIASISEAGIGSVAVCLINS
YANPANERKVAKILSEALPNIRVTTSADVKPVFREHTRFTLASIRATILPVMADYFERLQARLLEGGFSGNLMILKSNGG
MMGVDQARLRVEELVESGPAGGVGYATEIARTAGFPNIIHTDMGGTSFDASIIEDGQGLITREYEIEFDMPVAVPMLDIR
SIGAGGGSVGWVDSGGSLRVGPMSAGSVPGPACYGRGGTRPAITDANLVLGRISPDLSGKFKLDVQAARDAIETIATKLN
LTIEQCAEGMIRIATEAMAQAVKLVLASRGRDPRDYCFASFGGAGPLHACAVAEALGTPTVIVPRYSGVASAYGALRLAI
KHDEEVFHYAPLTAEELDRVGVKLQSLGEAAVDALVAQGAKAEDLRVSFVMRMRYAGQTFEVDVVQDRGAIDDRDVQQLA
SAFHEAHMREFGVRSDDFPVEIVALAVTAEAPSPAGPLESEQNSQLAPSQQKGRKVWFGDWTEALVHDVAGAQFVSGPAL
IEDPHTSIVIPPGWAARFDSARNCILERA

Sequences:

>Translated_669_residues
MWKVGVDVGGTFTDLFAVNTFTGEERTGKVLTTPEERSKGVLNAIANAELKPNEISLLVHGTTTATNALIERSFPDAAMI
TTEGFRDVLEIGRMHREHLYRPYQTKPAPLIRRRYRYAIAERTNAKGEVEEDIDAAQLKPIIASISEAGIGSVAVCLINS
YANPANERKVAKILSEALPNIRVTTSADVKPVFREHTRFTLASIRATILPVMADYFERLQARLLEGGFSGNLMILKSNGG
MMGVDQARLRVEELVESGPAGGVGYATEIARTAGFPNIIHTDMGGTSFDASIIEDGQGLITREYEIEFDMPVAVPMLDIR
SIGAGGGSVGWVDSGGSLRVGPMSAGSVPGPACYGRGGTRPAITDANLVLGRISPDLSGKFKLDVQAARDAIETIATKLN
LTIEQCAEGMIRIATEAMAQAVKLVLASRGRDPRDYCFASFGGAGPLHACAVAEALGTPTVIVPRYSGVASAYGALRLAI
KHDEEVFHYAPLTAEELDRVGVKLQSLGEAAVDALVAQGAKAEDLRVSFVMRMRYAGQTFEVDVVQDRGAIDDRDVQQLA
SAFHEAHMREFGVRSDDFPVEIVALAVTAEAPSPAGPLESEQNSQLAPSQQKGRKVWFGDWTEALVHDVAGAQFVSGPAL
IEDPHTSIVIPPGWAARFDSARNCILERA
>Mature_669_residues
MWKVGVDVGGTFTDLFAVNTFTGEERTGKVLTTPEERSKGVLNAIANAELKPNEISLLVHGTTTATNALIERSFPDAAMI
TTEGFRDVLEIGRMHREHLYRPYQTKPAPLIRRRYRYAIAERTNAKGEVEEDIDAAQLKPIIASISEAGIGSVAVCLINS
YANPANERKVAKILSEALPNIRVTTSADVKPVFREHTRFTLASIRATILPVMADYFERLQARLLEGGFSGNLMILKSNGG
MMGVDQARLRVEELVESGPAGGVGYATEIARTAGFPNIIHTDMGGTSFDASIIEDGQGLITREYEIEFDMPVAVPMLDIR
SIGAGGGSVGWVDSGGSLRVGPMSAGSVPGPACYGRGGTRPAITDANLVLGRISPDLSGKFKLDVQAARDAIETIATKLN
LTIEQCAEGMIRIATEAMAQAVKLVLASRGRDPRDYCFASFGGAGPLHACAVAEALGTPTVIVPRYSGVASAYGALRLAI
KHDEEVFHYAPLTAEELDRVGVKLQSLGEAAVDALVAQGAKAEDLRVSFVMRMRYAGQTFEVDVVQDRGAIDDRDVQQLA
SAFHEAHMREFGVRSDDFPVEIVALAVTAEAPSPAGPLESEQNSQLAPSQQKGRKVWFGDWTEALVHDVAGAQFVSGPAL
IEDPHTSIVIPPGWAARFDSARNCILERA

Specific function: Unknown

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Homo sapiens, GI48314820, Length=726, Percent_Identity=32.5068870523416, Blast_Score=251, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI133901900, Length=696, Percent_Identity=25.4310344827586, Blast_Score=162, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6322634, Length=736, Percent_Identity=29.2119565217391, Blast_Score=225, Evalue=2e-59,
Organism=Drosophila melanogaster, GI45550492, Length=723, Percent_Identity=29.4605809128631, Blast_Score=223, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: 3.5.2.14

Molecular weight: Translated: 71787; Mature: 71787

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWKVGVDVGGTFTDLFAVNTFTGEERTGKVLTTPEERSKGVLNAIANAELKPNEISLLVH
CEEEEECCCCCEEHHEEEEEECCCCCCCCEEECCHHHHCHHHHHHHCCCCCCCEEEEEEE
GTTTATNALIERSFPDAAMITTEGFRDVLEIGRMHREHLYRPYQTKPAPLIRRRYRYAIA
CCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ERTNAKGEVEEDIDAAQLKPIIASISEAGIGSVAVCLINSYANPANERKVAKILSEALPN
HCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
IRVTTSADVKPVFREHTRFTLASIRATILPVMADYFERLQARLLEGGFSGNLMILKSNGG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
MMGVDQARLRVEELVESGPAGGVGYATEIARTAGFPNIIHTDMGGTSFDASIIEDGQGLI
EECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCCCCEE
TREYEIEFDMPVAVPMLDIRSIGAGGGSVGWVDSGGSLRVGPMSAGSVPGPACYGRGGTR
EEEEEEEECCCCCCCHHHHHHCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCC
PAITDANLVLGRISPDLSGKFKLDVQAARDAIETIATKLNLTIEQCAEGMIRIATEAMAQ
CCEECCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVKLVLASRGRDPRDYCFASFGGAGPLHACAVAEALGTPTVIVPRYSGVASAYGALRLAI
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHEEEEE
KHDEEVFHYAPLTAEELDRVGVKLQSLGEAAVDALVAQGAKAEDLRVSFVMRMRYAGQTF
ECCCCEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEE
EVDVVQDRGAIDDRDVQQLASAFHEAHMREFGVRSDDFPVEIVALAVTAEAPSPAGPLES
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCC
EQNSQLAPSQQKGRKVWFGDWTEALVHDVAGAQFVSGPALIEDPHTSIVIPPGWAARFDS
CCCCCCCCCHHHCCEEEECCHHHHHHHHHCCCCEECCCCEEECCCCEEEECCCCHHHHHH
ARNCILERA
HHHHHHCCC
>Mature Secondary Structure
MWKVGVDVGGTFTDLFAVNTFTGEERTGKVLTTPEERSKGVLNAIANAELKPNEISLLVH
CEEEEECCCCCEEHHEEEEEECCCCCCCCEEECCHHHHCHHHHHHHCCCCCCCEEEEEEE
GTTTATNALIERSFPDAAMITTEGFRDVLEIGRMHREHLYRPYQTKPAPLIRRRYRYAIA
CCCHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
ERTNAKGEVEEDIDAAQLKPIIASISEAGIGSVAVCLINSYANPANERKVAKILSEALPN
HCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
IRVTTSADVKPVFREHTRFTLASIRATILPVMADYFERLQARLLEGGFSGNLMILKSNGG
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCC
MMGVDQARLRVEELVESGPAGGVGYATEIARTAGFPNIIHTDMGGTSFDASIIEDGQGLI
EECHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEEEECCCCCCCCHHHHCCCCCEE
TREYEIEFDMPVAVPMLDIRSIGAGGGSVGWVDSGGSLRVGPMSAGSVPGPACYGRGGTR
EEEEEEEECCCCCCCHHHHHHCCCCCCCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCC
PAITDANLVLGRISPDLSGKFKLDVQAARDAIETIATKLNLTIEQCAEGMIRIATEAMAQ
CCEECCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AVKLVLASRGRDPRDYCFASFGGAGPLHACAVAEALGTPTVIVPRYSGVASAYGALRLAI
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHEEEEE
KHDEEVFHYAPLTAEELDRVGVKLQSLGEAAVDALVAQGAKAEDLRVSFVMRMRYAGQTF
ECCCCEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEE
EVDVVQDRGAIDDRDVQQLASAFHEAHMREFGVRSDDFPVEIVALAVTAEAPSPAGPLES
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCC
EQNSQLAPSQQKGRKVWFGDWTEALVHDVAGAQFVSGPALIEDPHTSIVIPPGWAARFDS
CCCCCCCCCHHHCCEEEECCHHHHHHHHHCCCCEECCCCEEECCCCEEEECCCCHHHHHH
ARNCILERA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; N-methylimidazolidine-2,4-dione; H2O

Specific reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O = ADP + phosphate + N-carbamoylsarcosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]