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The map label for this gene is potC [H]

Identifier: 13488185

GI number: 13488185

Start: 16635

End: 17471

Strand: Direct

Name: potC [H]

Synonym: mlr9016

Alternate gene names: 13488185

Gene position: 16635-17471 (Clockwise)

Preceding gene: 13488184

Following gene: 13488186

Centisome position: 4.73

GC content: 58.18

Gene sequence:

>837_bases
ATGAGCATGCCGACCGCAACCGGGCGCTTCGGAATCGAGTGGCAGCTTGTCAATGGCATCACTTGCATGCTGCTGGCGCT
GATGCTTGCACCAATCTGTATGGTCCTGGTGATTTCGTTTACCAGCGGCGAGACGTTGCAGTTTCCGCCGCCGGCGCTTT
CACTGCGCTGGTATCAGGAGGTCTGGACAATGCTGGTCGGTCCGGACGCCGGGATCGGGAGATTGCGGGAGTCACTGCTT
GTCAGCCTGGAAATCGCGGCCCTAACTTCGCTTGTGTGCGTGCTTGCTGGTGTCCCGGCTTCCTATGCGCTGGTGCGATA
TCGTTTCGCCGGCAAGACGCTTATCGAAGAGTTGATCGGTCTGCCGGTGGTATTTCCAGCCGTTGTGCTTGGAATTGCGT
TGCTGGTTCTGGTAAGCGCCTCCGGTCTCGATTTTGGCATCTTTCAGATCGTCGTTGCCCATTCGATCATCGGACTGCCG
TTCCTCATGCGCAACTGCATGGCGGCGATGCGCGGCATTGATCCGATGTTGGAGGAGGCTGCGATGACGCTTGGTGCTTC
CGCGCCTAAGGTCTTTCGGGAGATTGTCTTGCCGCTTGCCAGCGGCGGTATCGCCTCCGGCGCCATCCTCGTCTTCATCT
TGTCTTTCAATGAATTCACGCTCAGCTATTTTCTCTACTCCGTCGATGTCTTCCCGCTCTCCATTTGGCTTTTCCAGCAG
GCGAACACATCCTTTAGCCCGGCGGTGTTCGCCGTGTCGTCGCTCATCGTCGTCGTCAACGTAGCGGCAGTCTTGGTCGT
TGACGCGGTGATCGGAAGTCGCGGATCGGCCGCCTAG

Upstream 100 bases:

>100_bases
GGCCGCTCGGTGCAGCACTATCGGTTTTGCTGATCCTGTTGGCACTCGCCGTGCAGTCGCTCAACCGCCTCATCGTCCGC
ACCAACGTGGAGATCAAGGG

Downstream 100 bases:

>100_bases
GAGCACACCAGAGGATTTGTTCAATGATATTTGACCCGTTCTGGTCAATCGAGCAACTATCGGAACGCTTCGCTCGGCGG
GAACTGTCGTCCGTGGAAGC

Product: ABC transporter permease

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MSMPTATGRFGIEWQLVNGITCMLLALMLAPICMVLVISFTSGETLQFPPPALSLRWYQEVWTMLVGPDAGIGRLRESLL
VSLEIAALTSLVCVLAGVPASYALVRYRFAGKTLIEELIGLPVVFPAVVLGIALLVLVSASGLDFGIFQIVVAHSIIGLP
FLMRNCMAAMRGIDPMLEEAAMTLGASAPKVFREIVLPLASGGIASGAILVFILSFNEFTLSYFLYSVDVFPLSIWLFQQ
ANTSFSPAVFAVSSLIVVVNVAAVLVVDAVIGSRGSAA

Sequences:

>Translated_278_residues
MSMPTATGRFGIEWQLVNGITCMLLALMLAPICMVLVISFTSGETLQFPPPALSLRWYQEVWTMLVGPDAGIGRLRESLL
VSLEIAALTSLVCVLAGVPASYALVRYRFAGKTLIEELIGLPVVFPAVVLGIALLVLVSASGLDFGIFQIVVAHSIIGLP
FLMRNCMAAMRGIDPMLEEAAMTLGASAPKVFREIVLPLASGGIASGAILVFILSFNEFTLSYFLYSVDVFPLSIWLFQQ
ANTSFSPAVFAVSSLIVVVNVAAVLVVDAVIGSRGSAA
>Mature_277_residues
SMPTATGRFGIEWQLVNGITCMLLALMLAPICMVLVISFTSGETLQFPPPALSLRWYQEVWTMLVGPDAGIGRLRESLLV
SLEIAALTSLVCVLAGVPASYALVRYRFAGKTLIEELIGLPVVFPAVVLGIALLVLVSASGLDFGIFQIVVAHSIIGLPF
LMRNCMAAMRGIDPMLEEAAMTLGASAPKVFREIVLPLASGGIASGAILVFILSFNEFTLSYFLYSVDVFPLSIWLFQQA
NTSFSPAVFAVSSLIVVVNVAAVLVVDAVIGSRGSAA

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=212, Percent_Identity=30.188679245283, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787714, Length=211, Percent_Identity=33.6492890995261, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788764, Length=174, Percent_Identity=29.8850574712644, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787081, Length=251, Percent_Identity=29.8804780876494, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786980, Length=156, Percent_Identity=36.5384615384615, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29533; Mature: 29402

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMPTATGRFGIEWQLVNGITCMLLALMLAPICMVLVISFTSGETLQFPPPALSLRWYQE
CCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
VWTMLVGPDAGIGRLRESLLVSLEIAALTSLVCVLAGVPASYALVRYRFAGKTLIEELIG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
LPVVFPAVVLGIALLVLVSASGLDFGIFQIVVAHSIIGLPFLMRNCMAAMRGIDPMLEEA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMTLGASAPKVFREIVLPLASGGIASGAILVFILSFNEFTLSYFLYSVDVFPLSIWLFQQ
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECC
ANTSFSPAVFAVSSLIVVVNVAAVLVVDAVIGSRGSAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SMPTATGRFGIEWQLVNGITCMLLALMLAPICMVLVISFTSGETLQFPPPALSLRWYQE
CCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHH
VWTMLVGPDAGIGRLRESLLVSLEIAALTSLVCVLAGVPASYALVRYRFAGKTLIEELIG
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
LPVVFPAVVLGIALLVLVSASGLDFGIFQIVVAHSIIGLPFLMRNCMAAMRGIDPMLEEA
CCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
AMTLGASAPKVFREIVLPLASGGIASGAILVFILSFNEFTLSYFLYSVDVFPLSIWLFQQ
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECC
ANTSFSPAVFAVSSLIVVVNVAAVLVVDAVIGSRGSAA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]