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The map label for this gene is ilvE [H]

Identifier: 13488121

GI number: 13488121

Start: 183978

End: 184853

Strand: Reverse

Name: ilvE [H]

Synonym: mll9205

Alternate gene names: 13488121

Gene position: 184853-183978 (Counterclockwise)

Preceding gene: 13488332

Following gene: 13488120

Centisome position: 52.53

GC content: 57.08

Gene sequence:

>876_bases
GTGGCGTTCATGGATGGTCAGTACCTGCCGATGTCCGAAGCCAAGGTGTCGGTTCTGGACTGGGGCTTTCTGCATTCCGA
TGCCACCTACGATACCGTTCATGTGTGGGACGGGAGGTTCTTTAGGCTGAATCTGCACGTGGACCGGTTCTTCCGCGGGA
TGGAAAAGCTCCGCATGAAGCTTCCCTACAACCGCAGTGAGATCGAAAAGATCCTGTCGACCTGTGTAGCGCTCTCCGGA
CACAAGTCGGCCTATGTCGAAATGATCTGTACGCGAGGTGGCTCGCCCACCTTTAGCCGGGACCCGCGCCAGTCGGAGAA
CCGGTTCATCGCATTCGCGGTGCCTTTCGGGTCGGTTGCCAACAAGGAGCAGCTCGAGCGCGGCCTGCATGTCGCCATCA
GCAACACTGTCCGGATCCCGCCCAAGTCGATCGATCCGACCATCAAGAACTATCACTGGCTCGATCTGGTGAAGGGCCTG
TTCGATGCGTACGACTATGGTGCCGAAACTGCATTGATCGTCGACATCAACGACAACATTGCCGAAGGGCCTGGCTTTAA
CGTTTTCACCGTCAAAGACGGCCGCTTGAAGACGCCGGCTTATGGTGTCCTTGCCGGCATTACCAGGCAGACCGTATTTG
ATCTGTGCGACGAACTGGGCCTATCCGTCAGCGCCGGCGACATTGATCGCAACGAACTGAAGGGCGCCGATGAGGTTTTC
ATCACGTCTACAGCAGGCGGGATCATGCCGGTGTCCAAGATTGACGAAACCGTTGTAGGCGACGGCAAGGTTGGCGCTCT
AACACGCCAGCTGGCAGACCTGTATTGGGAGAAGCATGCTGATCCCGCATGGTCGACAGCGGTAAATTACGCATAG

Upstream 100 bases:

>100_bases
ATTGGAGGACTCAGGAATGACAATTGCAGCAGCCGAACCTGCAACGACGCTCCCAGCCATAGAAAAACGGCACCAGGATC
AACGACAGTATCCTCACGGC

Downstream 100 bases:

>100_bases
TACCGCAACATACTGCCGAGAGGTCCTCCCCAGTGCGGGGAGGGCTGTGCTGCCGTGAGTCTGCCGATGACCGACGCTTT
CATTTCTCATCTCTCGAACG

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MAFMDGQYLPMSEAKVSVLDWGFLHSDATYDTVHVWDGRFFRLNLHVDRFFRGMEKLRMKLPYNRSEIEKILSTCVALSG
HKSAYVEMICTRGGSPTFSRDPRQSENRFIAFAVPFGSVANKEQLERGLHVAISNTVRIPPKSIDPTIKNYHWLDLVKGL
FDAYDYGAETALIVDINDNIAEGPGFNVFTVKDGRLKTPAYGVLAGITRQTVFDLCDELGLSVSAGDIDRNELKGADEVF
ITSTAGGIMPVSKIDETVVGDGKVGALTRQLADLYWEKHADPAWSTAVNYA

Sequences:

>Translated_291_residues
MAFMDGQYLPMSEAKVSVLDWGFLHSDATYDTVHVWDGRFFRLNLHVDRFFRGMEKLRMKLPYNRSEIEKILSTCVALSG
HKSAYVEMICTRGGSPTFSRDPRQSENRFIAFAVPFGSVANKEQLERGLHVAISNTVRIPPKSIDPTIKNYHWLDLVKGL
FDAYDYGAETALIVDINDNIAEGPGFNVFTVKDGRLKTPAYGVLAGITRQTVFDLCDELGLSVSAGDIDRNELKGADEVF
ITSTAGGIMPVSKIDETVVGDGKVGALTRQLADLYWEKHADPAWSTAVNYA
>Mature_290_residues
AFMDGQYLPMSEAKVSVLDWGFLHSDATYDTVHVWDGRFFRLNLHVDRFFRGMEKLRMKLPYNRSEIEKILSTCVALSGH
KSAYVEMICTRGGSPTFSRDPRQSENRFIAFAVPFGSVANKEQLERGLHVAISNTVRIPPKSIDPTIKNYHWLDLVKGLF
DAYDYGAETALIVDINDNIAEGPGFNVFTVKDGRLKTPAYGVLAGITRQTVFDLCDELGLSVSAGDIDRNELKGADEVFI
TSTAGGIMPVSKIDETVVGDGKVGALTRQLADLYWEKHADPAWSTAVNYA

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994963, Length=283, Percent_Identity=27.9151943462898, Blast_Score=112, Evalue=2e-26,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 32310; Mature: 32179

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFMDGQYLPMSEAKVSVLDWGFLHSDATYDTVHVWDGRFFRLNLHVDRFFRGMEKLRMK
CCCCCCCCCCCCCCEEEEEECEEECCCCCCCEEEEECCEEEEEEEEHHHHHHHHHHHHHH
LPYNRSEIEKILSTCVALSGHKSAYVEMICTRGGSPTFSRDPRQSENRFIAFAVPFGSVA
CCCCHHHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCC
NKEQLERGLHVAISNTVRIPPKSIDPTIKNYHWLDLVKGLFDAYDYGAETALIVDINDNI
CHHHHHCCCEEEEECEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
AEGPGFNVFTVKDGRLKTPAYGVLAGITRQTVFDLCDELGLSVSAGDIDRNELKGADEVF
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHCCCCCEEE
ITSTAGGIMPVSKIDETVVGDGKVGALTRQLADLYWEKHADPAWSTAVNYA
EEECCCCCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCC
>Mature Secondary Structure 
AFMDGQYLPMSEAKVSVLDWGFLHSDATYDTVHVWDGRFFRLNLHVDRFFRGMEKLRMK
CCCCCCCCCCCCCEEEEEECEEECCCCCCCEEEEECCEEEEEEEEHHHHHHHHHHHHHH
LPYNRSEIEKILSTCVALSGHKSAYVEMICTRGGSPTFSRDPRQSENRFIAFAVPFGSVA
CCCCHHHHHHHHHHHHHHCCCCHHEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCC
NKEQLERGLHVAISNTVRIPPKSIDPTIKNYHWLDLVKGLFDAYDYGAETALIVDINDNI
CHHHHHCCCEEEEECEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCC
AEGPGFNVFTVKDGRLKTPAYGVLAGITRQTVFDLCDELGLSVSAGDIDRNELKGADEVF
CCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHCCCCCEEE
ITSTAGGIMPVSKIDETVVGDGKVGALTRQLADLYWEKHADPAWSTAVNYA
EEECCCCCCCHHHCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]