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The map label for this gene is nadA2

Identifier: 13488072

GI number: 13488072

Start: 82712

End: 83686

Strand: Reverse

Name: nadA2

Synonym: mll9104

Alternate gene names: 13488072

Gene position: 83686-82712 (Counterclockwise)

Preceding gene: 13488073

Following gene: 13488071

Centisome position: 23.78

GC content: 62.36

Gene sequence:

>975_bases
ATGAGCACCATCCAGCCTTCGGCCGCTTTCCTGTATGACCGCGTCCAGCGCCTGATCCCGCCGATCGAATGGCCAGCCTT
CGCCGGCGACATCGATGCCATCCTTGATCTGAAGCGGCAGCGCAACGCCGTCATCCTGGCGCACAACTACCAGACACCGG
AGATTTTTCACTGTGTCGCCGATATCGTCGGCGACAGCCTGGCGCTGGCCCGCAAGGCGATGTCGACCGAAGCCGACGTC
ATTGTGCTGGCCGGCGTCCACTTCATGGCCGAGACGGCAAAGCTGCTCAATCCGCAAAAGACGGTGCTCATTCCCGATCT
GCGCGCAGGCTGTTCGCTGGCCGACTCGATTACTGCCGAGGACATTCGCCTGCTGCGACAACGCTATCCCGGCGTACCTG
TCGTGACCTACGTCAACACGTCGGCCGAGGTCAAAGCCGAGTCTGACATCTGCTGTACCTCCGGCAATGCCAAAGCCATC
GTCGAATCCCTTGGCGTCCCCAGGGTGATCATGCTGCCGGATGAGTATCTGGCTGAGAATATCGCCGCCCAGACCGACGT
CGAGATCATCGCCTGGAAAGGGCATTGCGAGGTGCATGAGCGCTTTACGCCGGCCGACATCCGCCAGCTGCGCGAGAACC
ATCCCGGTGTGATCGTGCTCGCGCATCCCGAATGTCCGCCCGACGTGGTCGCGGAGGCCGATTTTTCCGGTTCGACCGCG
GCAATGTCGGACTATGTCGAAAGGCAAAAGCCGCCACGCGTCGTGCTGCTGACGGAATGCTCGATGAGCGACAATGTCGC
GCTCCAGCATCCCGAGCTCGAGTTCATCCGGCCCTGCAATTTGTGCCCGCACATGAAGCGGATAACGCTCGCCAACATCC
GTTCGGCCCTGGAGCAGAACCGCCACGTCGTGACCATCGAGCCCGGGATCGCCGGGCGCGCGCGACTTGCCGTCGAGCGG
ATGCTCGCCGTATGA

Upstream 100 bases:

>100_bases
GTGGCTGGGACAAAATTGCCGCTGACGCGGGGTTGACATCTCTTATAGTCACAAAGATTATAAAGCCATTATAATCGTAT
AGACTATAATTGGAGGCTCG

Downstream 100 bases:

>100_bases
GCGCCGATGTCCGCAGCTTTTTTGGTCGACCCATCATCATTGGCGGTGGCATTGCCGGATTGTTGACCGCGCTTCATCTG
GCGCCAGAACCCGTGCTTGT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MSTIQPSAAFLYDRVQRLIPPIEWPAFAGDIDAILDLKRQRNAVILAHNYQTPEIFHCVADIVGDSLALARKAMSTEADV
IVLAGVHFMAETAKLLNPQKTVLIPDLRAGCSLADSITAEDIRLLRQRYPGVPVVTYVNTSAEVKAESDICCTSGNAKAI
VESLGVPRVIMLPDEYLAENIAAQTDVEIIAWKGHCEVHERFTPADIRQLRENHPGVIVLAHPECPPDVVAEADFSGSTA
AMSDYVERQKPPRVVLLTECSMSDNVALQHPELEFIRPCNLCPHMKRITLANIRSALEQNRHVVTIEPGIAGRARLAVER
MLAV

Sequences:

>Translated_324_residues
MSTIQPSAAFLYDRVQRLIPPIEWPAFAGDIDAILDLKRQRNAVILAHNYQTPEIFHCVADIVGDSLALARKAMSTEADV
IVLAGVHFMAETAKLLNPQKTVLIPDLRAGCSLADSITAEDIRLLRQRYPGVPVVTYVNTSAEVKAESDICCTSGNAKAI
VESLGVPRVIMLPDEYLAENIAAQTDVEIIAWKGHCEVHERFTPADIRQLRENHPGVIVLAHPECPPDVVAEADFSGSTA
AMSDYVERQKPPRVVLLTECSMSDNVALQHPELEFIRPCNLCPHMKRITLANIRSALEQNRHVVTIEPGIAGRARLAVER
MLAV
>Mature_323_residues
STIQPSAAFLYDRVQRLIPPIEWPAFAGDIDAILDLKRQRNAVILAHNYQTPEIFHCVADIVGDSLALARKAMSTEADVI
VLAGVHFMAETAKLLNPQKTVLIPDLRAGCSLADSITAEDIRLLRQRYPGVPVVTYVNTSAEVKAESDICCTSGNAKAIV
ESLGVPRVIMLPDEYLAENIAAQTDVEIIAWKGHCEVHERFTPADIRQLRENHPGVIVLAHPECPPDVVAEADFSGSTAA
MSDYVERQKPPRVVLLTECSMSDNVALQHPELEFIRPCNLCPHMKRITLANIRSALEQNRHVVTIEPGIAGRARLAVERM
LAV

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786964, Length=310, Percent_Identity=34.5161290322581, Blast_Score=162, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADA2_RHILO (Q982F2)

Other databases:

- EMBL:   BA000013
- RefSeq:   NP_085666.1
- ProteinModelPortal:   Q982F2
- SMR:   Q982F2
- GeneID:   1231553
- GenomeReviews:   BA000013_GR
- KEGG:   mlo:mll9104
- NMPDR:   fig|266835.1.peg.6820
- HOGENOM:   HBG291157
- OMA:   SMARMID
- ProtClustDB:   PRK09375
- GO:   GO:0005737
- HAMAP:   MF_00568
- InterPro:   IPR003473
- InterPro:   IPR023066
- TIGRFAMs:   TIGR00550

Pfam domain/function: PF02445 NadA

EC number: =2.5.1.72

Molecular weight: Translated: 35633; Mature: 35501

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: BINDING 48-48 BINDING 66-66 BINDING 137-137 BINDING 154-154 BINDING 222-222 BINDING 239-239

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIQPSAAFLYDRVQRLIPPIEWPAFAGDIDAILDLKRQRNAVILAHNYQTPEIFHCVA
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
DIVGDSLALARKAMSTEADVIVLAGVHFMAETAKLLNPQKTVLIPDLRAGCSLADSITAE
HHHCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCHH
DIRLLRQRYPGVPVVTYVNTSAEVKAESDICCTSGNAKAIVESLGVPRVIMLPDEYLAEN
HHHHHHHHCCCCCEEEEECCCCCEECCCCEEEECCCHHHHHHHCCCCEEEECCHHHHHHH
IAAQTDVEIIAWKGHCEVHERFTPADIRQLRENHPGVIVLAHPECPPDVVAEADFSGSTA
HCCCCCEEEEEECCCCHHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHEECCCCCCCHH
AMSDYVERQKPPRVVLLTECSMSDNVALQHPELEFIRPCNLCPHMKRITLANIRSALEQN
HHHHHHHHCCCCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHCC
RHVVTIEPGIAGRARLAVERMLAV
CCEEEECCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
STIQPSAAFLYDRVQRLIPPIEWPAFAGDIDAILDLKRQRNAVILAHNYQTPEIFHCVA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCHHHHHHHH
DIVGDSLALARKAMSTEADVIVLAGVHFMAETAKLLNPQKTVLIPDLRAGCSLADSITAE
HHHCCHHHHHHHHHCCCCCEEEEECHHHHHHHHHHCCCCCEEEECCCCCCCCHHHCCCHH
DIRLLRQRYPGVPVVTYVNTSAEVKAESDICCTSGNAKAIVESLGVPRVIMLPDEYLAEN
HHHHHHHHCCCCCEEEEECCCCCEECCCCEEEECCCHHHHHHHCCCCEEEECCHHHHHHH
IAAQTDVEIIAWKGHCEVHERFTPADIRQLRENHPGVIVLAHPECPPDVVAEADFSGSTA
HCCCCCEEEEEECCCCHHHCCCCHHHHHHHHHCCCCEEEEECCCCCHHHEECCCCCCCHH
AMSDYVERQKPPRVVLLTECSMSDNVALQHPELEFIRPCNLCPHMKRITLANIRSALEQN
HHHHHHHHCCCCCEEEEEECCCCCCEEEECCCHHHCCCCCCCCCHHHHHHHHHHHHHHCC
RHVVTIEPGIAGRARLAVERMLAV
CCEEEECCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11214968