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The map label for this gene is allR [H]

Identifier: 13488053

GI number: 13488053

Start: 9609

End: 10418

Strand: Reverse

Name: allR [H]

Synonym: mll9009

Alternate gene names: 13488053

Gene position: 10418-9609 (Counterclockwise)

Preceding gene: 13488054

Following gene: 13488052

Centisome position: 2.96

GC content: 57.65

Gene sequence:

>810_bases
GTGCACGTGAAGACGAACGAAAAGAAGGAGAAGGCGACTGGAACCCAATTGCTGGACCGTTCCATCGCTATCTTGAATCA
TCTTGGAGAGCTCGGCCGCGGCGGTGCGCGGGTTTCCGAGATTGCTGAAGCCTTCGGCCTAAATATGTCGACGGCACATC
GCATCATCAGCGGCCTGGAGCGACATCGCTACATCGAGCGCGACGACACTACAAAGCGGTACAGACTGGGGCTAGCCCTG
TTTGCGCTCGGAGCGAAAGCTGCGGACACGACGGGTATGCGACGCGTTTGTCATCCTGCTTTGCTACGAATTGCGGCCGA
AACGGGTGATACTGTCTTTCTTATGGCTCGCAACGGCTTCAACACCGTCTGTGTCGACCGACAGGACGGCGGCTACCGAA
TCGACAGCCTCACCGGACAGGTCGGTGGCCAGATACCCCTTGGGGTGGGTCCCGCCAGCCAGGCGATCTTGGCCATGCTG
CCACCAAACCAAGCCGAGGTCATTCTAGAAACCAACGCACCACAATTCGAGCGCTACCATGGATTGACAGCGGACGAAAT
CCGGCATGCGCTGCCAGAGATCCGCGGGCGCGGCTATGCCGTGGATGACGGGCACCTTGTGGAAGGAATTTCAGCGATAG
CGGTGCCAATCATCCTAGAAAGCGGAAATGTAGCAGGCGCGCTCGCCATCAACATGACTAGCGCAAGGCTGCGGAGGTGC
AGCGTAGGCGACTTCGTTCAGATTCTGCGACGTGAAATCGACGAAATCGAACGCACGATGAACCCACACGATGTTTCGAT
TGCCAGTTAA

Upstream 100 bases:

>100_bases
CCAACTGCCAATAGCCCTGTCGCTAGCCACGTTGAGAGCGGTCGTGATAGTTGGGTGACGATCTTGCGGATTGTTTTGAT
CCGTCGGCCGGTTGATCGAG

Downstream 100 bases:

>100_bases
GCTGGCAACCTTGTCAGAGCGGAGAGATATGGAGATGGAAGCCCCTGCTCACTACAATTTGATAGGAGACACAGGATCGC
GAGCCCCTGCAGTACATTGA

Product: transcription regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MHVKTNEKKEKATGTQLLDRSIAILNHLGELGRGGARVSEIAEAFGLNMSTAHRIISGLERHRYIERDDTTKRYRLGLAL
FALGAKAADTTGMRRVCHPALLRIAAETGDTVFLMARNGFNTVCVDRQDGGYRIDSLTGQVGGQIPLGVGPASQAILAML
PPNQAEVILETNAPQFERYHGLTADEIRHALPEIRGRGYAVDDGHLVEGISAIAVPIILESGNVAGALAINMTSARLRRC
SVGDFVQILRREIDEIERTMNPHDVSIAS

Sequences:

>Translated_269_residues
MHVKTNEKKEKATGTQLLDRSIAILNHLGELGRGGARVSEIAEAFGLNMSTAHRIISGLERHRYIERDDTTKRYRLGLAL
FALGAKAADTTGMRRVCHPALLRIAAETGDTVFLMARNGFNTVCVDRQDGGYRIDSLTGQVGGQIPLGVGPASQAILAML
PPNQAEVILETNAPQFERYHGLTADEIRHALPEIRGRGYAVDDGHLVEGISAIAVPIILESGNVAGALAINMTSARLRRC
SVGDFVQILRREIDEIERTMNPHDVSIAS
>Mature_269_residues
MHVKTNEKKEKATGTQLLDRSIAILNHLGELGRGGARVSEIAEAFGLNMSTAHRIISGLERHRYIERDDTTKRYRLGLAL
FALGAKAADTTGMRRVCHPALLRIAAETGDTVFLMARNGFNTVCVDRQDGGYRIDSLTGQVGGQIPLGVGPASQAILAML
PPNQAEVILETNAPQFERYHGLTADEIRHALPEIRGRGYAVDDGHLVEGISAIAVPIILESGNVAGALAINMTSARLRRC
SVGDFVQILRREIDEIERTMNPHDVSIAS

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=244, Percent_Identity=29.0983606557377, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1789999, Length=263, Percent_Identity=24.3346007604563, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788131, Length=248, Percent_Identity=24.5967741935484, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786468, Length=239, Percent_Identity=23.0125523012552, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI87082359, Length=249, Percent_Identity=22.4899598393574, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29182; Mature: 29182

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVKTNEKKEKATGTQLLDRSIAILNHLGELGRGGARVSEIAEAFGLNMSTAHRIISGLE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
RHRYIERDDTTKRYRLGLALFALGAKAADTTGMRRVCHPALLRIAAETGDTVFLMARNGF
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
NTVCVDRQDGGYRIDSLTGQVGGQIPLGVGPASQAILAMLPPNQAEVILETNAPQFERYH
CEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHC
GLTADEIRHALPEIRGRGYAVDDGHLVEGISAIAVPIILESGNVAGALAINMTSARLRRC
CCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHEEEEEEECCCEEEEEEEEEHHHHHHHC
SVGDFVQILRREIDEIERTMNPHDVSIAS
CHHHHHHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure
MHVKTNEKKEKATGTQLLDRSIAILNHLGELGRGGARVSEIAEAFGLNMSTAHRIISGLE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
RHRYIERDDTTKRYRLGLALFALGAKAADTTGMRRVCHPALLRIAAETGDTVFLMARNGF
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
NTVCVDRQDGGYRIDSLTGQVGGQIPLGVGPASQAILAMLPPNQAEVILETNAPQFERYH
CEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCCHHHHHC
GLTADEIRHALPEIRGRGYAVDDGHLVEGISAIAVPIILESGNVAGALAINMTSARLRRC
CCCHHHHHHHHHHHCCCCEECCCCHHHHHHHHHEEEEEEECCCEEEEEEEEEHHHHHHHC
SVGDFVQILRREIDEIERTMNPHDVSIAS
CHHHHHHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA