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The map label for this gene is atoC [H]

Identifier: 82791994

GI number: 82791994

Start: 2839367

End: 2839738

Strand: Reverse

Name: atoC [H]

Synonym: msl3517

Alternate gene names: 82791994

Gene position: 2839738-2839367 (Counterclockwise)

Preceding gene: 13473038

Following gene: 13473034

Centisome position: 40.36

GC content: 65.05

Gene sequence:

>372_bases
ATGGCAAAGCTTCTGATCGTCGAGGACGATGAATCCGTCCGCACCCTCGCAGCCCGCGCGCTCGAACGTGCCGGCCACGC
AATCGATATCGCCGCCGATGGCGCCCAGGGCCTGGCGCTGATCCGCGCCGCGCATGGCGGCTACGATCTCGTCGTCTCCG
ACATCCGCATGCCCGAGATGGACGGCATCGAGATGGCGATCGCGGCGGCCGCCCTTTTCCCGGCGATGAAGATCATGCTG
ATGACCGGTTATGCCGACCAGCGCGAGCGTGCCGAGGAGTTGAACGGCATCATCCTCGATGTCGTGCAGAAGCCGTTCAC
GCTGGCCGAAATCCGCTCACGCGTCGAACGGGCGCTGATCTGCTTCGCCTGA

Upstream 100 bases:

>100_bases
ACAAGTTCTGAAAAAGCCCTTAACGGCGCCGGAAAAATAGCCCGGTCAGGGGCTGGGTGCTTTCAGGAAAAGTCAACTTT
TCGCGGCCAAATTGCCGGCC

Downstream 100 bases:

>100_bases
TCAGACCGGATCGGCGGCGGCAAGCACGGGCGCTGCGCTCCTGCGCCGTGCTGTGTTGAGCGCGAGCAGGCCGGCGCCGA
TGATAAGCGCCGCGCCAATC

Product: response regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MAKLLIVEDDESVRTLAARALERAGHAIDIAADGAQGLALIRAAHGGYDLVVSDIRMPEMDGIEMAIAAAALFPAMKIML
MTGYADQRERAEELNGIILDVVQKPFTLAEIRSRVERALICFA

Sequences:

>Translated_123_residues
MAKLLIVEDDESVRTLAARALERAGHAIDIAADGAQGLALIRAAHGGYDLVVSDIRMPEMDGIEMAIAAAALFPAMKIML
MTGYADQRERAEELNGIILDVVQKPFTLAEIRSRVERALICFA
>Mature_122_residues
AKLLIVEDDESVRTLAARALERAGHAIDIAADGAQGLALIRAAHGGYDLVVSDIRMPEMDGIEMAIAAAALFPAMKIMLM
TGYADQRERAEELNGIILDVVQKPFTLAEIRSRVERALICFA

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=36.1344537815126, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=116, Percent_Identity=34.4827586206897, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=34.453781512605, Blast_Score=63, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 13324; Mature: 13193

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLLIVEDDESVRTLAARALERAGHAIDIAADGAQGLALIRAAHGGYDLVVSDIRMPEM
CCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHEEECCCCCEEEEECCCCCCC
DGIEMAIAAAALFPAMKIMLMTGYADQRERAEELNGIILDVVQKPFTLAEIRSRVERALI
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHH
CFA
CCC
>Mature Secondary Structure 
AKLLIVEDDESVRTLAARALERAGHAIDIAADGAQGLALIRAAHGGYDLVVSDIRMPEM
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHEEECCCCCEEEEECCCCCCC
DGIEMAIAAAALFPAMKIMLMTGYADQRERAEELNGIILDVVQKPFTLAEIRSRVERALI
CCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHH
CFA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]