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The map label for this gene is rhtB [H]

Identifier: 13476548

GI number: 13476548

Start: 6529784

End: 6530398

Strand: Direct

Name: rhtB [H]

Synonym: mlr7900

Alternate gene names: 13476548

Gene position: 6529784-6530398 (Clockwise)

Preceding gene: 13476547

Following gene: 13476551

Centisome position: 92.8

GC content: 66.83

Gene sequence:

>615_bases
ATGGACCTTGCCACCATCCTTGCTTTCGCGGCCGCCTTCTTCGTCTTTGCCGCCAGCCCAGGCCCCGACAACATGACCAT
CGTTGCCCGCACGATCTCCAGCGGCGCCGCGTCGGGCATCGCCTATGGCGCCGGCACGGTGGTAGGCATTCTTATCTTCC
TGATGCTCGCAGCCTTCGGCCTGTCGATCGTCGCCGCCAAGATGGCGATCGTCATGACGTTGCTTCGCTATGGGGGAGCG
GCCTATCTGATCTGGATGGGCGTCAAGCTCTGGACGGCCGTGCCCGTCGTGCCGGAGCTCCAGCCCGTCTCCGGCCGGCG
CGGGCTGCTGACGATCTTCGCCACCGGTGTCGCGCTCAATCTCGGCAATCCGAAAATGCCGCTGTTCTATGTGGCGCTGC
TGCCCAACGTCGTCGGTGCCTCGCTCACACCAGCGCATCTCGGCATCCTCGTCGCGGTGATCCTGGCTGTCGAGATTGTG
GTGATCGGCGGGCATGTCCTCCTTGCCGGCCGCGCCCGCAGCCTGTTGCGCACGCCCAGGATCGTGCGCCGGGTCAACCG
CGCGGCGGGGGGCGTCATGATCGGCGCCGGCGTTGCCGTGGTCGCCACGCGCTAA

Upstream 100 bases:

>100_bases
CTGCTGGTGTCACGGAGGCCCTGAATTTTCAGGCTATCGCCGGCAGGCAAATCGGCTAACCTGGACACCCGAGAGCAACA
CATGACTTTCGGGAGCCTTC

Downstream 100 bases:

>100_bases
AGCAATTCCAGGAACAATGTGAAACGGCTTTCCCGGGAAAAGCGCATAGCGCTTCGCCTTGGAAGGCGCGCCAACGCAAA
GGGTTGGAGAGTGCTCAATC

Product: hypothetical protein

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MDLATILAFAAAFFVFAASPGPDNMTIVARTISSGAASGIAYGAGTVVGILIFLMLAAFGLSIVAAKMAIVMTLLRYGGA
AYLIWMGVKLWTAVPVVPELQPVSGRRGLLTIFATGVALNLGNPKMPLFYVALLPNVVGASLTPAHLGILVAVILAVEIV
VIGGHVLLAGRARSLLRTPRIVRRVNRAAGGVMIGAGVAVVATR

Sequences:

>Translated_204_residues
MDLATILAFAAAFFVFAASPGPDNMTIVARTISSGAASGIAYGAGTVVGILIFLMLAAFGLSIVAAKMAIVMTLLRYGGA
AYLIWMGVKLWTAVPVVPELQPVSGRRGLLTIFATGVALNLGNPKMPLFYVALLPNVVGASLTPAHLGILVAVILAVEIV
VIGGHVLLAGRARSLLRTPRIVRRVNRAAGGVMIGAGVAVVATR
>Mature_204_residues
MDLATILAFAAAFFVFAASPGPDNMTIVARTISSGAASGIAYGAGTVVGILIFLMLAAFGLSIVAAKMAIVMTLLRYGGA
AYLIWMGVKLWTAVPVVPELQPVSGRRGLLTIFATGVALNLGNPKMPLFYVALLPNVVGASLTPAHLGILVAVILAVEIV
VIGGHVLLAGRARSLLRTPRIVRRVNRAAGGVMIGAGVAVVATR

Specific function: Conducts the efflux of homoserine and homoserine lactone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=209, Percent_Identity=25.3588516746411, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788099, Length=186, Percent_Identity=26.3440860215054, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 20929; Mature: 20929

Theoretical pI: Translated: 12.06; Mature: 12.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLATILAFAAAFFVFAASPGPDNMTIVARTISSGAASGIAYGAGTVVGILIFLMLAAFG
CCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSIVAAKMAIVMTLLRYGGAAYLIWMGVKLWTAVPVVPELQPVSGRRGLLTIFATGVALN
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECEEEE
LGNPKMPLFYVALLPNVVGASLTPAHLGILVAVILAVEIVVIGGHVLLAGRARSLLRTPR
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
IVRRVNRAAGGVMIGAGVAVVATR
HHHHHHHHHCCEEEECCEEEEECC
>Mature Secondary Structure
MDLATILAFAAAFFVFAASPGPDNMTIVARTISSGAASGIAYGAGTVVGILIFLMLAAFG
CCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSIVAAKMAIVMTLLRYGGAAYLIWMGVKLWTAVPVVPELQPVSGRRGLLTIFATGVALN
HHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECEEEE
LGNPKMPLFYVALLPNVVGASLTPAHLGILVAVILAVEIVVIGGHVLLAGRARSLLRTPR
CCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
IVRRVNRAAGGVMIGAGVAVVATR
HHHHHHHHHCCEEEECCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]