Click here to switch to the map view.

The map label for this gene is yafC [H]

Identifier: 13476483

GI number: 13476483

Start: 6465102

End: 6466034

Strand: Direct

Name: yafC [H]

Synonym: mlr7815

Alternate gene names: 13476483

Gene position: 6465102-6466034 (Clockwise)

Preceding gene: 13476481

Following gene: 13476484

Centisome position: 91.89

GC content: 65.17

Gene sequence:

>933_bases
ATGGATAAGTCCGACATTACATTCGAGCGCATGCGCAGCTTCGTTCGCGTGGCCGAGCGTGGCAGCCTGTCGGCCGTCGC
GCGGGAATTTGGTGTCGGGCAGTCAACGATCACGCGGCATGTGCGGGAACTGGAAGAAGCTGTCGGCGTGCCTTTGCTCA
GCAGGACGACCCGGCGGGTCACGATGACCGCCGAAGGCAGCCGCTATTATGCCAATAGCGTTCAGATCCTGCGCCTCGTC
GAACAGGCCAGCGATGAGGCCCGGGGCACGCGCGGCGCGCCCGCCGGCACGATCCGGATAAGCTGCACGGCGGCCTTTGG
CGTCTTGCACGTCAGCCGCCTGATCTTCGCTTTTCAGGACCGTCATCCCGACATAGGGGTTGACCTCAGCCTCACGGATG
AGCGGGTGGACCTCGTCCGTGAGGGTGTCGATATCGCACTTCGGCTGGGCCCGCTCACGGACAGCTCGTTGAAGCTGCGG
GCTCTCGGCCAGTCGCGGCGCCTGCTCGTGGCGTCTCCGGACTATCTTGCGGCGCGGGGAAGACCGGCCGACCCTTCAGA
TCTGTCCCGGCATGAGGGCATCCGGATGTCGAACGTGGCGGGCAGCGAAACGCTTGCTTTGCAGGGCGCCGACGGCCAAC
GCCACACGGTGCCTTTCGCCGGGCGACTGCGTATCGATCATGGACTTGCCGCGCGGCAGGCCATGATCGCCGCTCGCGGG
ATCGCGCCGGCGCATCGATGGCTGGTGGACGATCTCCTGGCTGCGGGCTTGCTCGAGACGATCCTTGCGGATTATTCGCT
GCCGTCCGTCCCGCTGAACATGTTGATCGTCCCGGAGCGCGCGGGCGTCGCAAGGGTCCGCTTGCTGGTCGAGTTTCTGG
CTGAGCAGATTGCCGCCATTCCAGGGATCGAGAAATCCCTGTCGGAGCATTAG

Upstream 100 bases:

>100_bases
CTTTCATGGGTCAGATCCGGTATTGAGGAAACTGACGCAAACGTAGTCAACGACGATACGATCCACTATATGCAGGTAAT
GCATAATATTGTGCCGAATA

Downstream 100 bases:

>100_bases
CCGCCGTCCGATCTGCCCGGAAGAGTAGCTTGCGGCGGTGCCGTTCATCGTCTATCGCCGATGAACGATGACAGAATCCG
CCCTTGAACCAGACCGCGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MDKSDITFERMRSFVRVAERGSLSAVAREFGVGQSTITRHVRELEEAVGVPLLSRTTRRVTMTAEGSRYYANSVQILRLV
EQASDEARGTRGAPAGTIRISCTAAFGVLHVSRLIFAFQDRHPDIGVDLSLTDERVDLVREGVDIALRLGPLTDSSLKLR
ALGQSRRLLVASPDYLAARGRPADPSDLSRHEGIRMSNVAGSETLALQGADGQRHTVPFAGRLRIDHGLAARQAMIAARG
IAPAHRWLVDDLLAAGLLETILADYSLPSVPLNMLIVPERAGVARVRLLVEFLAEQIAAIPGIEKSLSEH

Sequences:

>Translated_310_residues
MDKSDITFERMRSFVRVAERGSLSAVAREFGVGQSTITRHVRELEEAVGVPLLSRTTRRVTMTAEGSRYYANSVQILRLV
EQASDEARGTRGAPAGTIRISCTAAFGVLHVSRLIFAFQDRHPDIGVDLSLTDERVDLVREGVDIALRLGPLTDSSLKLR
ALGQSRRLLVASPDYLAARGRPADPSDLSRHEGIRMSNVAGSETLALQGADGQRHTVPFAGRLRIDHGLAARQAMIAARG
IAPAHRWLVDDLLAAGLLETILADYSLPSVPLNMLIVPERAGVARVRLLVEFLAEQIAAIPGIEKSLSEH
>Mature_310_residues
MDKSDITFERMRSFVRVAERGSLSAVAREFGVGQSTITRHVRELEEAVGVPLLSRTTRRVTMTAEGSRYYANSVQILRLV
EQASDEARGTRGAPAGTIRISCTAAFGVLHVSRLIFAFQDRHPDIGVDLSLTDERVDLVREGVDIALRLGPLTDSSLKLR
ALGQSRRLLVASPDYLAARGRPADPSDLSRHEGIRMSNVAGSETLALQGADGQRHTVPFAGRLRIDHGLAARQAMIAARG
IAPAHRWLVDDLLAAGLLETILADYSLPSVPLNMLIVPERAGVARVRLLVEFLAEQIAAIPGIEKSLSEH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=297, Percent_Identity=34.3434343434343, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=33.9100346020761, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=26.4084507042254, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789639, Length=293, Percent_Identity=27.6450511945392, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1787128, Length=267, Percent_Identity=28.0898876404494, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI145693193, Length=297, Percent_Identity=29.96632996633, Blast_Score=111, Evalue=6e-26,
Organism=Escherichia coli, GI1787589, Length=192, Percent_Identity=30.7291666666667, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI157672245, Length=228, Percent_Identity=27.6315789473684, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693105, Length=205, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=291, Percent_Identity=22.680412371134, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787879, Length=147, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787601, Length=137, Percent_Identity=27.007299270073, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788706, Length=166, Percent_Identity=24.6987951807229, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33691; Mature: 33691

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKSDITFERMRSFVRVAERGSLSAVAREFGVGQSTITRHVRELEEAVGVPLLSRTTRRV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCEEE
TMTAEGSRYYANSVQILRLVEQASDEARGTRGAPAGTIRISCTAAFGVLHVSRLIFAFQD
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHC
RHPDIGVDLSLTDERVDLVREGVDIALRLGPLTDSSLKLRALGQSRRLLVASPDYLAARG
CCCCCCEEEEECHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCCHHHCCC
RPADPSDLSRHEGIRMSNVAGSETLALQGADGQRHTVPFAGRLRIDHGLAARQAMIAARG
CCCCHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHC
IAPAHRWLVDDLLAAGLLETILADYSLPSVPLNMLIVPERAGVARVRLLVEFLAEQIAAI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
PGIEKSLSEH
CCCHHHHCCC
>Mature Secondary Structure
MDKSDITFERMRSFVRVAERGSLSAVAREFGVGQSTITRHVRELEEAVGVPLLSRTTRRV
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHCCCCEEE
TMTAEGSRYYANSVQILRLVEQASDEARGTRGAPAGTIRISCTAAFGVLHVSRLIFAFQD
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHC
RHPDIGVDLSLTDERVDLVREGVDIALRLGPLTDSSLKLRALGQSRRLLVASPDYLAARG
CCCCCCEEEEECHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCEEEEECCCHHHCCC
RPADPSDLSRHEGIRMSNVAGSETLALQGADGQRHTVPFAGRLRIDHGLAARQAMIAARG
CCCCHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCHHHHHHHHHHHC
IAPAHRWLVDDLLAAGLLETILADYSLPSVPLNMLIVPERAGVARVRLLVEFLAEQIAAI
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHC
PGIEKSLSEH
CCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]