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The map label for this gene is yafC [C]

Identifier: 13476459

GI number: 13476459

Start: 6443103

End: 6444023

Strand: Direct

Name: yafC [C]

Synonym: mlr7786

Alternate gene names: 13476459

Gene position: 6443103-6444023 (Clockwise)

Preceding gene: 13476454

Following gene: 13476463

Centisome position: 91.57

GC content: 63.41

Gene sequence:

>921_bases
ATGTCGAAAGCTCCGGATTTTGAAGGTTTGGCCATGTTCGCCAAGGTCGCGGAGGAGCGTTCCTTTGCCGCCGCCGCGCG
CGTGCTCGGCCTGTCGGTGGCGACCGTGTCACGCGGTGTCAGCCGTCTGGAGGAGCGGCTTGGCGCCCGGCTTTTCAACC
GGACGTCGCGGCGTCTGGCACTAACGGATTTCGGTCATCGGCTCGCCGAGCGTGCGTCCCGTCTCTACCGCGATGCGGAG
GACGCCGAGAACGCGGCCCGCGAACTGTCGGCCAGTCCGCGCGGTCTTGTACGTCTGGCCGTTCCAATGTCGTTCGGGCT
GAGGTGGGTGGCGCCGCTGCTCCCTGATTTCTTCAAGCTCTATCCCGACGTGTCGATTGACATGCATCTAAGCGATGCAG
TCGTCGATCTGATCGGCGAGGGGTTCGACGCAGCCTTGCGGATTGCCGTGTTGCCGGATTCTTCGCTGGTTGCCCGGCGC
CTGTGTAGTATTGCGCCGTTCATCGTTGCTGCACCATCCTATCTCGCCAGGCATGGCCGGCCGAGCACGCCACGCGACCT
CGACGCACATCACTGTCTTGGCTATGCCTATCGGCCGCGACAGGATGTCTGGCATTTCAGCAATGCCGCGGGCGATGAAG
AGGTTGTCACCCCGTCAGGACCATTGCGGGTCACCAATTCCGACGCCCTTGTTCCGACCGTGCTGGCCGGAATCGCGATC
GCCGAGCTGCCGGAATTCATTGCCAGCGAGTATCTTGCCGATGGGCGCCTGCAAGCGATCCTGACCGACTGGACTTTGCC
GAGGGGAGCGCTGTATTTCGTAACGCCGTCGGCTCGCGCGCGCCCGGCGAAGGTCGAAGCCGTCGCGGGTTTTATGGCTG
CCCACCTGTCAAGACCGAGCTGGCAGCCGATCAATCCATAG

Upstream 100 bases:

>100_bases
TTGTCATTTTCGTCACTCCTGTTGTGGGTGACAGAGACATATGGACAGGTTGATCATTTCGAAATAGCAATGCTTGCAAA
CAATCATTGCAGGATTGGCG

Downstream 100 bases:

>100_bases
AGGGCACGGCGTCTGCCTCCCGAATGGATCAGCCGGTCTGGCTGTGTAGCGCACGCGCCTTCAACAGACGCTGGATGTCC
GCCGCCTTCGACGGCACGCC

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MSKAPDFEGLAMFAKVAEERSFAAAARVLGLSVATVSRGVSRLEERLGARLFNRTSRRLALTDFGHRLAERASRLYRDAE
DAENAARELSASPRGLVRLAVPMSFGLRWVAPLLPDFFKLYPDVSIDMHLSDAVVDLIGEGFDAALRIAVLPDSSLVARR
LCSIAPFIVAAPSYLARHGRPSTPRDLDAHHCLGYAYRPRQDVWHFSNAAGDEEVVTPSGPLRVTNSDALVPTVLAGIAI
AELPEFIASEYLADGRLQAILTDWTLPRGALYFVTPSARARPAKVEAVAGFMAAHLSRPSWQPINP

Sequences:

>Translated_306_residues
MSKAPDFEGLAMFAKVAEERSFAAAARVLGLSVATVSRGVSRLEERLGARLFNRTSRRLALTDFGHRLAERASRLYRDAE
DAENAARELSASPRGLVRLAVPMSFGLRWVAPLLPDFFKLYPDVSIDMHLSDAVVDLIGEGFDAALRIAVLPDSSLVARR
LCSIAPFIVAAPSYLARHGRPSTPRDLDAHHCLGYAYRPRQDVWHFSNAAGDEEVVTPSGPLRVTNSDALVPTVLAGIAI
AELPEFIASEYLADGRLQAILTDWTLPRGALYFVTPSARARPAKVEAVAGFMAAHLSRPSWQPINP
>Mature_305_residues
SKAPDFEGLAMFAKVAEERSFAAAARVLGLSVATVSRGVSRLEERLGARLFNRTSRRLALTDFGHRLAERASRLYRDAED
AENAARELSASPRGLVRLAVPMSFGLRWVAPLLPDFFKLYPDVSIDMHLSDAVVDLIGEGFDAALRIAVLPDSSLVARRL
CSIAPFIVAAPSYLARHGRPSTPRDLDAHHCLGYAYRPRQDVWHFSNAAGDEEVVTPSGPLRVTNSDALVPTVLAGIAIA
ELPEFIASEYLADGRLQAILTDWTLPRGALYFVTPSARARPAKVEAVAGFMAAHLSRPSWQPINP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=33.4470989761092, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787128, Length=276, Percent_Identity=30.4347826086957, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1789639, Length=279, Percent_Identity=30.4659498207885, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI87081978, Length=298, Percent_Identity=31.2080536912752, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI145693193, Length=302, Percent_Identity=29.1390728476821, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1789440, Length=308, Percent_Identity=26.2987012987013, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787589, Length=277, Percent_Identity=28.158844765343, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788706, Length=288, Percent_Identity=28.8194444444444, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1789173, Length=296, Percent_Identity=26.0135135135135, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790262, Length=242, Percent_Identity=32.2314049586777, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI157672245, Length=204, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1790011, Length=261, Percent_Identity=25.6704980842912, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI145693105, Length=194, Percent_Identity=24.2268041237113, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788748, Length=123, Percent_Identity=31.7073170731707, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33339; Mature: 33208

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAPDFEGLAMFAKVAEERSFAAAARVLGLSVATVSRGVSRLEERLGARLFNRTSRRLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEH
LTDFGHRLAERASRLYRDAEDAENAARELSASPRGLVRLAVPMSFGLRWVAPLLPDFFKL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
YPDVSIDMHLSDAVVDLIGEGFDAALRIAVLPDSSLVARRLCSIAPFIVAAPSYLARHGR
CCCCEEEEEHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHCCC
PSTPRDLDAHHCLGYAYRPRQDVWHFSNAAGDEEVVTPSGPLRVTNSDALVPTVLAGIAI
CCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCCCCEECCCCCEEECCCCCHHHHHHHHHHH
AELPEFIASEYLADGRLQAILTDWTLPRGALYFVTPSARARPAKVEAVAGFMAAHLSRPS
HHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
WQPINP
CCCCCC
>Mature Secondary Structure 
SKAPDFEGLAMFAKVAEERSFAAAARVLGLSVATVSRGVSRLEERLGARLFNRTSRRLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEH
LTDFGHRLAERASRLYRDAEDAENAARELSASPRGLVRLAVPMSFGLRWVAPLLPDFFKL
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHH
YPDVSIDMHLSDAVVDLIGEGFDAALRIAVLPDSSLVARRLCSIAPFIVAAPSYLARHGR
CCCCEEEEEHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCHHHHHHCCC
PSTPRDLDAHHCLGYAYRPRQDVWHFSNAAGDEEVVTPSGPLRVTNSDALVPTVLAGIAI
CCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCCCCEECCCCCEEECCCCCHHHHHHHHHHH
AELPEFIASEYLADGRLQAILTDWTLPRGALYFVTPSARARPAKVEAVAGFMAAHLSRPS
HHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCC
WQPINP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]