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The map label for this gene is 13476438

Identifier: 13476438

GI number: 13476438

Start: 6425863

End: 6426264

Strand: Direct

Name: 13476438

Synonym: mlr7758

Alternate gene names: NA

Gene position: 6425863-6426264 (Clockwise)

Preceding gene: 13476437

Following gene: 13476439

Centisome position: 91.33

GC content: 60.2

Gene sequence:

>402_bases
ATGCATGAAAACAAATTCGAAACGATCGTCGGGATCGATCATTTCGTGCTGACGGTGGCGTCGCTCGAAGCGACCTGCGC
CTTTTACCAGCGCGTGCTGGGTTTCGAGCGCATCGACACGCCGGGCCGGCCAACAGCGCTGGCTTTTGGCAGCCAGAAGA
TCAATGTCCATGAAATCCGCCGCACTTTCGAGCCGAAGGCGAAGGTGGCGACGCCAGGGTCGGGCGATTTCTGCCTGGTT
ACCGGACGACCGCTCGACGAAATCCGTGCCCGTCTCGAAGCCAATGGCGTTGCGCTCGAACTGGGACCGGTCGAGCGCAT
TGGGGCGCGCGGTCCGATGATGTCTGTCTATTTCCGCGATCCGGACGGCAATCTTGTCGAAGTCAGCCAGTACTTGCGGT
AG

Upstream 100 bases:

>100_bases
CCGCCGGAGCTTGCCGCGATACCTGCGGTCAAGCCTGGCAGCCGCAACATCTGACCGTGGATGTCGCCCAAAAGTGTGCA
GCGGTTTTGGGAGTAACGAC

Downstream 100 bases:

>100_bases
TGTCTCAGGCATCCGGCTGCGACAATAAGCCGAAGCCATTCTCAAATTCGCCGCGATTGTCGGGTGTTGGAGACGTGAAC
CTTACCAAAGATTATGGCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 133

Protein sequence:

>133_residues
MHENKFETIVGIDHFVLTVASLEATCAFYQRVLGFERIDTPGRPTALAFGSQKINVHEIRRTFEPKAKVATPGSGDFCLV
TGRPLDEIRARLEANGVALELGPVERIGARGPMMSVYFRDPDGNLVEVSQYLR

Sequences:

>Translated_133_residues
MHENKFETIVGIDHFVLTVASLEATCAFYQRVLGFERIDTPGRPTALAFGSQKINVHEIRRTFEPKAKVATPGSGDFCLV
TGRPLDEIRARLEANGVALELGPVERIGARGPMMSVYFRDPDGNLVEVSQYLR
>Mature_133_residues
MHENKFETIVGIDHFVLTVASLEATCAFYQRVLGFERIDTPGRPTALAFGSQKINVHEIRRTFEPKAKVATPGSGDFCLV
TGRPLDEIRARLEANGVALELGPVERIGARGPMMSVYFRDPDGNLVEVSQYLR

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=121, Percent_Identity=51.2396694214876, Blast_Score=132, Evalue=8e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14749; Mature: 14749

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHENKFETIVGIDHFVLTVASLEATCAFYQRVLGFERIDTPGRPTALAFGSQKINVHEIR
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEECCCCCCHHHHH
RTFEPKAKVATPGSGDFCLVTGRPLDEIRARLEANGVALELGPVERIGARGPMMSVYFRD
HHCCCCCEEECCCCCCEEEEECCCHHHHHHHHHCCCEEEEECCHHHHCCCCCEEEEEEEC
PDGNLVEVSQYLR
CCCCEEHHHHHCC
>Mature Secondary Structure
MHENKFETIVGIDHFVLTVASLEATCAFYQRVLGFERIDTPGRPTALAFGSQKINVHEIR
CCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCEEEEECCCCCCHHHHH
RTFEPKAKVATPGSGDFCLVTGRPLDEIRARLEANGVALELGPVERIGARGPMMSVYFRD
HHCCCCCEEECCCCCCEEEEECCCHHHHHHHHHCCCEEEEECCHHHHCCCCCEEEEEEEC
PDGNLVEVSQYLR
CCCCEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]