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The map label for this gene is degP1 [H]

Identifier: 13476388

GI number: 13476388

Start: 6367272

End: 6368822

Strand: Direct

Name: degP1 [H]

Synonym: mlr7692

Alternate gene names: 13476388

Gene position: 6367272-6368822 (Clockwise)

Preceding gene: 13476387

Following gene: 13476389

Centisome position: 90.49

GC content: 64.86

Gene sequence:

>1551_bases
ATGAATATTGCCCCCAATTCATATTCCCGCACCCGCAAGCGTCTCCTGGCTGCCGCTGCTTCCGTCGCCGTTGCCGGCGT
GATCGGCGTTGGCGCGCTGACCAGCGGAACCAGCCCCGTTCTGGCCGACGCCGTACGCGTCGAGGCGCCGCAGGTGCAAG
GCTTCGCCGATGTCGTCGAGCGCGTTTCGCCCGCCGTGGTCAGCGTCAAGGTGAAGGCCAAGATCCAGCCGACCGCCGAT
GACGGCTCCGATGACCAGGATGGCTTCGACAATCTTCCCAACAATCCGCAGCTGCGCCGCTTCTTCAAGGAATTCCGCGG
CTTTGGCGATCAGGGCGGCCAGAATGATGAAGGCCATCGCCGCTTCGGTCACCGCGACCGCAGCAATGACCAGCCGCGCC
CGGTGGCGCAGGGCTCCGGCTTCTTCATCTCCGAGGACGGCTACCTCGTCACCAACAACCACGTCGTCGAAGAAGGCACC
GCCTTCACCGTGGTGACCAATGACGGCAAGGAACTCGACGCCAAGCTGGTCGGCACCGACCCGCGCACCGATCTCGCCGT
GCTCAAGGTCGAAGGCGGTGGCAAGTTCACCTATGTCGACTTCGCCGACGATTCCAAGGTTCGCGTCGGCGACTGGGTCG
TGGCCGTCGGCAATCCGTTCGGCCTCGGCGGCACGGTCACCGCCGGCATCGTGTCGGCGCGCGGCCGTGACATCGGCGCC
GGCCCCTATGACGATTTCCTGCAGATCGACGCCTCGGTCAACCGCGGCAATTCGGGTGGCCCGACCTTCAACCTCAATGG
CCAGGTGGTCGGTATCAACACGGCGATCTTCTCGCCCTCGGGCGGCAGTGTCGGCATCGCCTTCGACATTCCTGCCTCGA
CCGCCAAGCAGGTTGTCGAGGACCTGATGAAGAGCGGCGCGGTGCAGCGCGGCTGGCTCGGCGTCGAAATCCAGCCGGTT
ACCTCCGACATCGCCGAATCGCTCGGTCTGAAGTCCAACAATGGCGCGTTGGTGTCCAGCGCCCAGGACGATGGCCCCGG
CAAGAAGGCCGGCATCACGGCTGGTGACGTCATCACCCAGGTCGAGGGCAAGGACGTCGCTTCGCCGAAGGAACTCGCCC
GCCTGATTGGCGCCTATTCGCCCGGCAAGTCGGTTGACGTCACCGTCTGGCGCGACGGCAAGAGCCAGACGATCAAGGTC
GATCTCGGCAAGCTGCCGGCCAGCGACAAGCAGGCCTCGAACGACCAGCAGCAGCAGCCTGCCGCTCCGGCAAAACCTGA
TACGCTGGCCGATCTCGGCCTCACCGTCACCAAGTCCGAAAACGGCAAGGGGCTTGTGGTGACCGATGTCGATCCCGAAA
GCGCTGCGGCCGACCGCGGCATCCAGCCGGGAGACATCATCACCGCGGTCAATTCGAACGAAGTGAATGGCACCGACGAT
GTCACCAAGGCGATGACCGACGCGGTGAAGTCCGGCCGCAAGGCGGTGCTGATGCAGATCACCCGCGACAACAACAACCG
TTTTGTCGCGCTGCCCGTCGCCAAGGGCTGA

Upstream 100 bases:

>100_bases
TCATGCGTCGGAAATGGCGCTGTAATGTGCGCCGCTCTAATTCTCCTTTCCTGAGGATGCCGATCAAGGCGCGTCCCTTT
GAAAGAGGATACGAGACCCC

Downstream 100 bases:

>100_bases
CACCGACTTTTCCGGTGCGGCGGTATCAAACACCCCCCGAGCCGCCACATGGGAAAGCATGGAGCCGGGTACGTTAGTCA
GTCATCGTGCTCTCCTCCAG

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 516

Protein sequence:

>516_residues
MNIAPNSYSRTRKRLLAAAASVAVAGVIGVGALTSGTSPVLADAVRVEAPQVQGFADVVERVSPAVVSVKVKAKIQPTAD
DGSDDQDGFDNLPNNPQLRRFFKEFRGFGDQGGQNDEGHRRFGHRDRSNDQPRPVAQGSGFFISEDGYLVTNNHVVEEGT
AFTVVTNDGKELDAKLVGTDPRTDLAVLKVEGGGKFTYVDFADDSKVRVGDWVVAVGNPFGLGGTVTAGIVSARGRDIGA
GPYDDFLQIDASVNRGNSGGPTFNLNGQVVGINTAIFSPSGGSVGIAFDIPASTAKQVVEDLMKSGAVQRGWLGVEIQPV
TSDIAESLGLKSNNGALVSSAQDDGPGKKAGITAGDVITQVEGKDVASPKELARLIGAYSPGKSVDVTVWRDGKSQTIKV
DLGKLPASDKQASNDQQQQPAAPAKPDTLADLGLTVTKSENGKGLVVTDVDPESAAADRGIQPGDIITAVNSNEVNGTDD
VTKAMTDAVKSGRKAVLMQITRDNNNRFVALPVAKG

Sequences:

>Translated_516_residues
MNIAPNSYSRTRKRLLAAAASVAVAGVIGVGALTSGTSPVLADAVRVEAPQVQGFADVVERVSPAVVSVKVKAKIQPTAD
DGSDDQDGFDNLPNNPQLRRFFKEFRGFGDQGGQNDEGHRRFGHRDRSNDQPRPVAQGSGFFISEDGYLVTNNHVVEEGT
AFTVVTNDGKELDAKLVGTDPRTDLAVLKVEGGGKFTYVDFADDSKVRVGDWVVAVGNPFGLGGTVTAGIVSARGRDIGA
GPYDDFLQIDASVNRGNSGGPTFNLNGQVVGINTAIFSPSGGSVGIAFDIPASTAKQVVEDLMKSGAVQRGWLGVEIQPV
TSDIAESLGLKSNNGALVSSAQDDGPGKKAGITAGDVITQVEGKDVASPKELARLIGAYSPGKSVDVTVWRDGKSQTIKV
DLGKLPASDKQASNDQQQQPAAPAKPDTLADLGLTVTKSENGKGLVVTDVDPESAAADRGIQPGDIITAVNSNEVNGTDD
VTKAMTDAVKSGRKAVLMQITRDNNNRFVALPVAKG
>Mature_516_residues
MNIAPNSYSRTRKRLLAAAASVAVAGVIGVGALTSGTSPVLADAVRVEAPQVQGFADVVERVSPAVVSVKVKAKIQPTAD
DGSDDQDGFDNLPNNPQLRRFFKEFRGFGDQGGQNDEGHRRFGHRDRSNDQPRPVAQGSGFFISEDGYLVTNNHVVEEGT
AFTVVTNDGKELDAKLVGTDPRTDLAVLKVEGGGKFTYVDFADDSKVRVGDWVVAVGNPFGLGGTVTAGIVSARGRDIGA
GPYDDFLQIDASVNRGNSGGPTFNLNGQVVGINTAIFSPSGGSVGIAFDIPASTAKQVVEDLMKSGAVQRGWLGVEIQPV
TSDIAESLGLKSNNGALVSSAQDDGPGKKAGITAGDVITQVEGKDVASPKELARLIGAYSPGKSVDVTVWRDGKSQTIKV
DLGKLPASDKQASNDQQQQPAAPAKPDTLADLGLTVTKSENGKGLVVTDVDPESAAADRGIQPGDIITAVNSNEVNGTDD
VTKAMTDAVKSGRKAVLMQITRDNNNRFVALPVAKG

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=282, Percent_Identity=33.6879432624113, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI24308541, Length=256, Percent_Identity=33.984375, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI22129776, Length=268, Percent_Identity=31.7164179104478, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI7019477, Length=244, Percent_Identity=31.9672131147541, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1789629, Length=463, Percent_Identity=37.3650107991361, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI1786356, Length=445, Percent_Identity=35.7303370786517, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1789630, Length=295, Percent_Identity=37.2881355932203, Blast_Score=179, Evalue=4e-46,
Organism=Drosophila melanogaster, GI24646839, Length=299, Percent_Identity=29.7658862876254, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 53705; Mature: 53705

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIAPNSYSRTRKRLLAAAASVAVAGVIGVGALTSGTSPVLADAVRVEAPQVQGFADVVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHH
RVSPAVVSVKVKAKIQPTADDGSDDQDGFDNLPNNPQLRRFFKEFRGFGDQGGQNDEGHR
HCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
RFGHRDRSNDQPRPVAQGSGFFISEDGYLVTNNHVVEEGTAFTVVTNDGKELDAKLVGTD
HCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCEEEECCCEEEEEECCCCEECEEEECCC
PRTDLAVLKVEGGGKFTYVDFADDSKVRVGDWVVAVGNPFGLGGTVTAGIVSARGRDIGA
CCCCEEEEEECCCCEEEEEEECCCCCEEECCEEEECCCCCCCCCHHHHHHHCCCCCCCCC
GPYDDFLQIDASVNRGNSGGPTFNLNGQVVGINTAIFSPSGGSVGIAFDIPASTAKQVVE
CCCCCCEEEEEECCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEECCHHHHHHHHH
DLMKSGAVQRGWLGVEIQPVTSDIAESLGLKSNNGALVSSAQDDGPGKKAGITAGDVITQ
HHHHCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHEEEE
VEGKDVASPKELARLIGAYSPGKSVDVTVWRDGKSQTIKVDLGKLPASDKQASNDQQQQP
ECCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHCC
AAPAKPDTLADLGLTVTKSENGKGLVVTDVDPESAAADRGIQPGDIITAVNSNEVNGTDD
CCCCCCCCHHHCCEEEEECCCCCEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCHH
VTKAMTDAVKSGRKAVLMQITRDNNNRFVALPVAKG
HHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEECCC
>Mature Secondary Structure
MNIAPNSYSRTRKRLLAAAASVAVAGVIGVGALTSGTSPVLADAVRVEAPQVQGFADVVE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHHHH
RVSPAVVSVKVKAKIQPTADDGSDDQDGFDNLPNNPQLRRFFKEFRGFGDQGGQNDEGHR
HCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHH
RFGHRDRSNDQPRPVAQGSGFFISEDGYLVTNNHVVEEGTAFTVVTNDGKELDAKLVGTD
HCCCCCCCCCCCCCCCCCCCEEEECCCEEEECCEEEECCCEEEEEECCCCEECEEEECCC
PRTDLAVLKVEGGGKFTYVDFADDSKVRVGDWVVAVGNPFGLGGTVTAGIVSARGRDIGA
CCCCEEEEEECCCCEEEEEEECCCCCEEECCEEEECCCCCCCCCHHHHHHHCCCCCCCCC
GPYDDFLQIDASVNRGNSGGPTFNLNGQVVGINTAIFSPSGGSVGIAFDIPASTAKQVVE
CCCCCCEEEEEECCCCCCCCCEEECCCEEEEEEEEEECCCCCCEEEEEECCHHHHHHHHH
DLMKSGAVQRGWLGVEIQPVTSDIAESLGLKSNNGALVSSAQDDGPGKKAGITAGDVITQ
HHHHCCCCCCCEEEEEEECCHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCHHHEEEE
VEGKDVASPKELARLIGAYSPGKSVDVTVWRDGKSQTIKVDLGKLPASDKQASNDQQQQP
ECCCCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHCC
AAPAKPDTLADLGLTVTKSENGKGLVVTDVDPESAAADRGIQPGDIITAVNSNEVNGTDD
CCCCCCCCHHHCCEEEEECCCCCEEEEEECCCCHHHHHCCCCCCCEEEEECCCCCCCCHH
VTKAMTDAVKSGRKAVLMQITRDNNNRFVALPVAKG
HHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550509; 11481430 [H]