Click here to switch to the map view.

The map label for this gene is xanB [H]

Identifier: 13476320

GI number: 13476320

Start: 6296519

End: 6298759

Strand: Direct

Name: xanB [H]

Synonym: mlr7607

Alternate gene names: 13476320

Gene position: 6296519-6298759 (Clockwise)

Preceding gene: 13476319

Following gene: 13476326

Centisome position: 89.49

GC content: 64.79

Gene sequence:

>2241_bases
ATGAGTCAGCGCATCGTCAGTTTTGTCATGAGCGGCGGCGTCGGCTCGCGGCTCTGGCCGCTGTCGCGCGAGGACAATCC
GAAGCAGTTTCACGATTTTTCGGGTGATGGCTCCATGCTGGCCAAGACCTTGCGCCGCCTGGCGGCAAGGCCCGACGGTC
AAACTCCGATCTTCCTGATCGCTTCGGAACGCCATGCCGACCGCGTCCGTGCCGATCTCGCCGGCCTCGATCTTGCCGGC
GGCGGTCCGCTGTTCGAGCCCACAGGGCGCAACACCGCCGCGGCGGTGGCCCTTGCAACGCTGCGCACTTTGTCCGAATT
CGGCGACAGCCTGGTGCTGGTGGTGCCGTCGGACCACGAAATATCGACGGCAGGGCAATTCTGGCAGAGCGTTGAGGCGG
GCACTGAGGCGGCACGCGCCGGCCGGCTCGTTGTGTTCGGCATCAAGCCGACGCAGCCCGAAACCGGCTATGGCTATATC
GAGGTCTCCGCCGAGAAGGGCGGGGTATCAGACGTTTCGCGCTTCGTCGAAAAGCCGGACCTGGCGACCGCGCAAGGCTA
CCTCGAAGCCGGAAACTTTTATTGGAACACCGGCATTTTCCTGTTTCGCGCCGCTGCCATGCGCGACGCTTTCGCCGTGT
TCCAGCCGGACATCTGGCGGGCGACCGAAGCCGCTTACAAGGCGGCGACATCGGATCTGTCAGGCCTCTACATGCCGCTC
GACCTCTACGCGGCCATCCCGTCCAATTCGATCGACTATGCCATCATGGAGCGGGCGAGGGACATCGCGATGGTGCCGGC
CGGCTTTCGCTGGAACGATCTCGGTTCCTGGCAGTCGTTGCTCGATGTCGGCCCTGCCGATGACCAGGGCAATGTCATTG
TCGGCGACGTCGTCGCCATCGATTGCGAGAACTCCTACATCCGCAGCGAAGGGCGCCTCTTGTCGGCGATCGGCATGAAG
GACGTCGCCATCGTTTCGACCGCCGATGCCACGTTCGTGGCTCCGGTCAGCCACAGCCAGCATGTCAAGAAGGTGGTCGA
GCAACTGGAGAAGTCGGGCCGGCTGGAAACCAGGTTCACCCCGGCGCATGACCGCGTCATCGAAAGCGGCGCCTGGCGGC
GGCGCGTGCACCACTGGCTGTTCCAGGAAACCTTGCCGCTGTGGTCGACATCGGGCGTCGACGAGCGCCACGGCGGCTTC
CACGAAGCGCTCGGCTTCGACGGCGCCCCGCTGATGAAGCCGAAGCGCATGCGCACGCAGGCCCGCCAGGTCTATGCCTT
TGCGGTTGCCAAGGAGCACGGCTGGACTGGGCCGGCCGAGCGGCTGATCGCGCATGGCATCGACTTCATGGCTGGGAAGG
GCCGCACCGAACGCGGCGGTTGGGTGCGCACGCTGAATGTCGACGGCGCTGTCGCCGACGCCACGGAAGACGCCTACGAT
CATTCCTGCGTACTGCTGGCGCTGGCGCATGCGCATATGTCGGGCAATACGGATGCTCTTCGGCTCGGTGAAGAGACTTT
CGCCTTTCTCGACGCACATCTCGAGGACAGCCGCATGACCGGCTTTCTCGAGACGTCGGATGGGGAGGGCGAGCGGCGCT
CAAACCCGCACATGCATTTGCTGGAGGCCTTTCTCGCCTGGTATCAGGCGACCGGCGAGCGTGCCCATCTGCGCCGCGCG
GCTCGCATCATCGACCTCTTCCGCAGCCATTTCTTCGACGCCGAGAGCTGGACGCTCGGCGAATATTTCGATGCCGAATG
GAAACCGTCGACTGGCGAGAAAGGGTCCTGGACCGAGCCTGGCCATCATTTTGAATGGGCTTCGCTCCTGGTCGATTTCG
CCGAGCGCAGCGGCCAGGCCGAACTGAGCGGCTTCGCGAGGAAACTTTACGCTTCGGCCATCGCCAACGGCCTCAACCGG
GCCACCGGTCTTGCCTATGGCGCCGTCTCCAGGCAGGGCCTGCCGCTCGACCTGATCTCGCGCAGCTGGCCGCAGGCCGA
AGCCATCAAGGCGGCGATCGCGTTGGACGGCTCGGGCGGTCCCGACCTGAAGCCCGAGATCGAGGCCCGTGTCGGCCGGC
TTTTCCGCTGGCACATCGACCCGGCGCCGCTCGGCCTGTGGATCGATCGCATAGACGAACGCGGCCGCTCGCTGGCGTCG
GATGTTCCGGCCAGCATCTTCTATCATCTGGTCTGCGCGCTGACGCAGTATCTGGATAGGACGGCAAAGAAGGCGGTCTA
G

Upstream 100 bases:

>100_bases
TAAGGCCTTCATCGACCTGGCGGTCGAGCGGATTTCCAATCGGGCAAACACGGCTTAAGGCATGTCTGCTACCTCCGACC
AACTTCTCAGCGAGACCACA

Downstream 100 bases:

>100_bases
GCTCGGCTCAATACGGGCTCGCCACGTCCCCAGTCTCGACATAGATCGACTTCAGCTGCGAATAGAGCGCCAATGCCGCC
AGCGAATTCTCGCGGCCGAT

Product: phosphomannose isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 746; Mature: 745

Protein sequence:

>746_residues
MSQRIVSFVMSGGVGSRLWPLSREDNPKQFHDFSGDGSMLAKTLRRLAARPDGQTPIFLIASERHADRVRADLAGLDLAG
GGPLFEPTGRNTAAAVALATLRTLSEFGDSLVLVVPSDHEISTAGQFWQSVEAGTEAARAGRLVVFGIKPTQPETGYGYI
EVSAEKGGVSDVSRFVEKPDLATAQGYLEAGNFYWNTGIFLFRAAAMRDAFAVFQPDIWRATEAAYKAATSDLSGLYMPL
DLYAAIPSNSIDYAIMERARDIAMVPAGFRWNDLGSWQSLLDVGPADDQGNVIVGDVVAIDCENSYIRSEGRLLSAIGMK
DVAIVSTADATFVAPVSHSQHVKKVVEQLEKSGRLETRFTPAHDRVIESGAWRRRVHHWLFQETLPLWSTSGVDERHGGF
HEALGFDGAPLMKPKRMRTQARQVYAFAVAKEHGWTGPAERLIAHGIDFMAGKGRTERGGWVRTLNVDGAVADATEDAYD
HSCVLLALAHAHMSGNTDALRLGEETFAFLDAHLEDSRMTGFLETSDGEGERRSNPHMHLLEAFLAWYQATGERAHLRRA
ARIIDLFRSHFFDAESWTLGEYFDAEWKPSTGEKGSWTEPGHHFEWASLLVDFAERSGQAELSGFARKLYASAIANGLNR
ATGLAYGAVSRQGLPLDLISRSWPQAEAIKAAIALDGSGGPDLKPEIEARVGRLFRWHIDPAPLGLWIDRIDERGRSLAS
DVPASIFYHLVCALTQYLDRTAKKAV

Sequences:

>Translated_746_residues
MSQRIVSFVMSGGVGSRLWPLSREDNPKQFHDFSGDGSMLAKTLRRLAARPDGQTPIFLIASERHADRVRADLAGLDLAG
GGPLFEPTGRNTAAAVALATLRTLSEFGDSLVLVVPSDHEISTAGQFWQSVEAGTEAARAGRLVVFGIKPTQPETGYGYI
EVSAEKGGVSDVSRFVEKPDLATAQGYLEAGNFYWNTGIFLFRAAAMRDAFAVFQPDIWRATEAAYKAATSDLSGLYMPL
DLYAAIPSNSIDYAIMERARDIAMVPAGFRWNDLGSWQSLLDVGPADDQGNVIVGDVVAIDCENSYIRSEGRLLSAIGMK
DVAIVSTADATFVAPVSHSQHVKKVVEQLEKSGRLETRFTPAHDRVIESGAWRRRVHHWLFQETLPLWSTSGVDERHGGF
HEALGFDGAPLMKPKRMRTQARQVYAFAVAKEHGWTGPAERLIAHGIDFMAGKGRTERGGWVRTLNVDGAVADATEDAYD
HSCVLLALAHAHMSGNTDALRLGEETFAFLDAHLEDSRMTGFLETSDGEGERRSNPHMHLLEAFLAWYQATGERAHLRRA
ARIIDLFRSHFFDAESWTLGEYFDAEWKPSTGEKGSWTEPGHHFEWASLLVDFAERSGQAELSGFARKLYASAIANGLNR
ATGLAYGAVSRQGLPLDLISRSWPQAEAIKAAIALDGSGGPDLKPEIEARVGRLFRWHIDPAPLGLWIDRIDERGRSLAS
DVPASIFYHLVCALTQYLDRTAKKAV
>Mature_745_residues
SQRIVSFVMSGGVGSRLWPLSREDNPKQFHDFSGDGSMLAKTLRRLAARPDGQTPIFLIASERHADRVRADLAGLDLAGG
GPLFEPTGRNTAAAVALATLRTLSEFGDSLVLVVPSDHEISTAGQFWQSVEAGTEAARAGRLVVFGIKPTQPETGYGYIE
VSAEKGGVSDVSRFVEKPDLATAQGYLEAGNFYWNTGIFLFRAAAMRDAFAVFQPDIWRATEAAYKAATSDLSGLYMPLD
LYAAIPSNSIDYAIMERARDIAMVPAGFRWNDLGSWQSLLDVGPADDQGNVIVGDVVAIDCENSYIRSEGRLLSAIGMKD
VAIVSTADATFVAPVSHSQHVKKVVEQLEKSGRLETRFTPAHDRVIESGAWRRRVHHWLFQETLPLWSTSGVDERHGGFH
EALGFDGAPLMKPKRMRTQARQVYAFAVAKEHGWTGPAERLIAHGIDFMAGKGRTERGGWVRTLNVDGAVADATEDAYDH
SCVLLALAHAHMSGNTDALRLGEETFAFLDAHLEDSRMTGFLETSDGEGERRSNPHMHLLEAFLAWYQATGERAHLRRAA
RIIDLFRSHFFDAESWTLGEYFDAEWKPSTGEKGSWTEPGHHFEWASLLVDFAERSGQAELSGFARKLYASAIANGLNRA
TGLAYGAVSRQGLPLDLISRSWPQAEAIKAAIALDGSGGPDLKPEIEARVGRLFRWHIDPAPLGLWIDRIDERGRSLASD
VPASIFYHLVCALTQYLDRTAKKAV

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=366, Percent_Identity=43.4426229508197, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI87082342, Length=278, Percent_Identity=28.7769784172662, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 81827; Mature: 81696

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRIVSFVMSGGVGSRLWPLSREDNPKQFHDFSGDGSMLAKTLRRLAARPDGQTPIFLI
CCHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
ASERHADRVRADLAGLDLAGGGPLFEPTGRNTAAAVALATLRTLSEFGDSLVLVVPSDHE
ECCCCHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCC
ISTAGQFWQSVEAGTEAARAGRLVVFGIKPTQPETGYGYIEVSAEKGGVSDVSRFVEKPD
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCC
LATAQGYLEAGNFYWNTGIFLFRAAAMRDAFAVFQPDIWRATEAAYKAATSDLSGLYMPL
CCHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECH
DLYAAIPSNSIDYAIMERARDIAMVPAGFRWNDLGSWQSLLDVGPADDQGNVIVGDVVAI
HHHEECCCCCCCHHHHHHCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEEE
DCENSYIRSEGRLLSAIGMKDVAIVSTADATFVAPVSHSQHVKKVVEQLEKSGRLETRFT
ECCCCCHHCCCCEEECCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEC
PAHDRVIESGAWRRRVHHWLFQETLPLWSTSGVDERHGGFHEALGFDGAPLMKPKRMRTQ
CHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCHHHHHH
ARQVYAFAVAKEHGWTGPAERLIAHGIDFMAGKGRTERGGWVRTLNVDGAVADATEDAYD
HHHHHHHEEECCCCCCCHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHCC
HSCVLLALAHAHMSGNTDALRLGEETFAFLDAHLEDSRMTGFLETSDGEGERRSNPHMHL
CHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHH
LEAFLAWYQATGERAHLRRAARIIDLFRSHFFDAESWTLGEYFDAEWKPSTGEKGSWTEP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
GHHFEWASLLVDFAERSGQAELSGFARKLYASAIANGLNRATGLAYGAVSRQGLPLDLIS
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RSWPQAEAIKAAIALDGSGGPDLKPEIEARVGRLFRWHIDPAPLGLWIDRIDERGRSLAS
CCCCHHHHHEEEEEECCCCCCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHH
DVPASIFYHLVCALTQYLDRTAKKAV
CCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQRIVSFVMSGGVGSRLWPLSREDNPKQFHDFSGDGSMLAKTLRRLAARPDGQTPIFLI
CHHHHHHHHCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCCCCEEEE
ASERHADRVRADLAGLDLAGGGPLFEPTGRNTAAAVALATLRTLSEFGDSLVLVVPSDHE
ECCCCHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCC
ISTAGQFWQSVEAGTEAARAGRLVVFGIKPTQPETGYGYIEVSAEKGGVSDVSRFVEKPD
CHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCC
LATAQGYLEAGNFYWNTGIFLFRAAAMRDAFAVFQPDIWRATEAAYKAATSDLSGLYMPL
CCHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEECH
DLYAAIPSNSIDYAIMERARDIAMVPAGFRWNDLGSWQSLLDVGPADDQGNVIVGDVVAI
HHHEECCCCCCCHHHHHHCCCEEECCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEEE
DCENSYIRSEGRLLSAIGMKDVAIVSTADATFVAPVSHSQHVKKVVEQLEKSGRLETRFT
ECCCCCHHCCCCEEECCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHHHCCCCEEEEC
PAHDRVIESGAWRRRVHHWLFQETLPLWSTSGVDERHGGFHEALGFDGAPLMKPKRMRTQ
CHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHCCCHHHHCCCCCCCCCCCHHHHHH
ARQVYAFAVAKEHGWTGPAERLIAHGIDFMAGKGRTERGGWVRTLNVDGAVADATEDAYD
HHHHHHHEEECCCCCCCHHHHHHHHCCHHHCCCCCCCCCCEEEEEECCCCCCCCCCHHCC
HSCVLLALAHAHMSGNTDALRLGEETFAFLDAHLEDSRMTGFLETSDGEGERRSNPHMHL
CHHHHHHHHHHHCCCCCCCEEECHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHH
LEAFLAWYQATGERAHLRRAARIIDLFRSHFFDAESWTLGEYFDAEWKPSTGEKGSWTEP
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCC
GHHFEWASLLVDFAERSGQAELSGFARKLYASAIANGLNRATGLAYGAVSRQGLPLDLIS
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
RSWPQAEAIKAAIALDGSGGPDLKPEIEARVGRLFRWHIDPAPLGLWIDRIDERGRSLAS
CCCCHHHHHEEEEEECCCCCCCCCHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHH
DVPASIFYHLVCALTQYLDRTAKKAV
CCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]