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The map label for this gene is yhcS [C]

Identifier: 13476319

GI number: 13476319

Start: 6295577

End: 6296476

Strand: Direct

Name: yhcS [C]

Synonym: mlr7606

Alternate gene names: 13476319

Gene position: 6295577-6296476 (Clockwise)

Preceding gene: 13476314

Following gene: 13476320

Centisome position: 89.48

GC content: 65.44

Gene sequence:

>900_bases
ATGGTCGATCTCAACGATGTCGTCGTGTTTGCCCGCGTCGTCGAAGCCGGTAGCTTCACCGCTGCCGCGCGCCTGCTGGC
CATGCCCAAGACGACCGTCAGCCGCCGTGTCGCCGCGCTTGAGCGCGAGGTCGGAGTGCGGCTGCTGCAGCGCACCACAC
GCAGCCTCAACCTGACGGATGCCGGGCGTCTCTACTATGAGCAAAGCAGCCAGGGGCTGCGGACGATCGAGGAGGCGAAC
CTTCGTCTTGCGGAGGCAAGGGCGGAGCCTTCGGGCACGATCCGCATTTCGGCCCCGGTTGGTTTTGGCGGTCACTTCCT
CATCCGCGCCGTGGTCGACTTTCTGGCTCTGTACCCGAAGACCAATGTCGAGTTGCGCCTCACCGACGACAAGCTCAACC
TGATCGAGGACGGCATCGACCTTGCCTTCCGCACCGGAAGGCTTGAGGATTCGACGCTCATCGCCCGCAAGCTGGGTTCC
ACGCACAGGCTGCTCTGCGCCAGCCATGACTATCTCGCACGCTACGGGATTCCGGAAGGCCCGGCCGATCTTGCCCGCCA
TCGATGCGTCATCGCGGGTCCGTCGGCCTCAGGCGCTCATTGGGTGCTGGATGGACCACAAGGCCAGGAAACTGTCGTGG
TCGCCGGGCGCTTCGCCGCCAATGAGATGCAGGCGGTGGCGGCGGCCGCGCTCGCCGGTTTCGGCATCGCCCAATTGCCG
CAGCCGATGGCCGACGGGCTGATCAACGAGGGGCGGTTGCGGCGCGTTCTCGACGGCTACACGACGCCGGCCGGCGGCCT
GCACGTTCTCTTTCCCAGCAGCCGGCACCTTTCACCCCTGGTTAAGGCCTTCATCGACCTGGCGGTCGAGCGGATTTCCA
ATCGGGCAAACACGGCTTAA

Upstream 100 bases:

>100_bases
TCATTTGCTCCTTGTCGGTTTGTCTGGAGCAAAATTAGGCTCTATCTCATTGATGCATAATTGCCTATAATTGGAAAAAC
CTGTCCCATTAATGAATACA

Downstream 100 bases:

>100_bases
GGCATGTCTGCTACCTCCGACCAACTTCTCAGCGAGACCACAATGAGTCAGCGCATCGTCAGTTTTGTCATGAGCGGCGG
CGTCGGCTCGCGGCTCTGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MVDLNDVVVFARVVEAGSFTAAARLLAMPKTTVSRRVAALEREVGVRLLQRTTRSLNLTDAGRLYYEQSSQGLRTIEEAN
LRLAEARAEPSGTIRISAPVGFGGHFLIRAVVDFLALYPKTNVELRLTDDKLNLIEDGIDLAFRTGRLEDSTLIARKLGS
THRLLCASHDYLARYGIPEGPADLARHRCVIAGPSASGAHWVLDGPQGQETVVVAGRFAANEMQAVAAAALAGFGIAQLP
QPMADGLINEGRLRRVLDGYTTPAGGLHVLFPSSRHLSPLVKAFIDLAVERISNRANTA

Sequences:

>Translated_299_residues
MVDLNDVVVFARVVEAGSFTAAARLLAMPKTTVSRRVAALEREVGVRLLQRTTRSLNLTDAGRLYYEQSSQGLRTIEEAN
LRLAEARAEPSGTIRISAPVGFGGHFLIRAVVDFLALYPKTNVELRLTDDKLNLIEDGIDLAFRTGRLEDSTLIARKLGS
THRLLCASHDYLARYGIPEGPADLARHRCVIAGPSASGAHWVLDGPQGQETVVVAGRFAANEMQAVAAAALAGFGIAQLP
QPMADGLINEGRLRRVLDGYTTPAGGLHVLFPSSRHLSPLVKAFIDLAVERISNRANTA
>Mature_299_residues
MVDLNDVVVFARVVEAGSFTAAARLLAMPKTTVSRRVAALEREVGVRLLQRTTRSLNLTDAGRLYYEQSSQGLRTIEEAN
LRLAEARAEPSGTIRISAPVGFGGHFLIRAVVDFLALYPKTNVELRLTDDKLNLIEDGIDLAFRTGRLEDSTLIARKLGS
THRLLCASHDYLARYGIPEGPADLARHRCVIAGPSASGAHWVLDGPQGQETVVVAGRFAANEMQAVAAAALAGFGIAQLP
QPMADGLINEGRLRRVLDGYTTPAGGLHVLFPSSRHLSPLVKAFIDLAVERISNRANTA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=287, Percent_Identity=35.5400696864112, Blast_Score=164, Evalue=4e-42,
Organism=Escherichia coli, GI145693193, Length=298, Percent_Identity=33.5570469798658, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1786401, Length=289, Percent_Identity=35.2941176470588, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1787128, Length=287, Percent_Identity=29.9651567944251, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI87081978, Length=263, Percent_Identity=32.6996197718631, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1789440, Length=262, Percent_Identity=29.7709923664122, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787589, Length=287, Percent_Identity=30.3135888501742, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789173, Length=251, Percent_Identity=29.0836653386454, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=172, Percent_Identity=29.6511627906977, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788481, Length=299, Percent_Identity=25.4180602006689, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI145693105, Length=244, Percent_Identity=22.1311475409836, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788706, Length=183, Percent_Identity=26.775956284153, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1786713, Length=282, Percent_Identity=29.4326241134752, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=24.6666666666667, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32226; Mature: 32226

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDLNDVVVFARVVEAGSFTAAARLLAMPKTTVSRRVAALEREVGVRLLQRTTRSLNLTD
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AGRLYYEQSSQGLRTIEEANLRLAEARAEPSGTIRISAPVGFGGHFLIRAVVDFLALYPK
CCCEEEECCCCHHHHHHHHCCEEEHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
TNVELRLTDDKLNLIEDGIDLAFRTGRLEDSTLIARKLGSTHRLLCASHDYLARYGIPEG
CCEEEEEECCHHHHHHHCCHHEEECCCCCCHHHHHHHCCCCCEEEEECCHHHHHCCCCCC
PADLARHRCVIAGPSASGAHWVLDGPQGQETVVVAGRFAANEMQAVAAAALAGFGIAQLP
HHHHHHCEEEEECCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHCC
QPMADGLINEGRLRRVLDGYTTPAGGLHVLFPSSRHLSPLVKAFIDLAVERISNRANTA
CHHHHCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVDLNDVVVFARVVEAGSFTAAARLLAMPKTTVSRRVAALEREVGVRLLQRTTRSLNLTD
CCCHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AGRLYYEQSSQGLRTIEEANLRLAEARAEPSGTIRISAPVGFGGHFLIRAVVDFLALYPK
CCCEEEECCCCHHHHHHHHCCEEEHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCC
TNVELRLTDDKLNLIEDGIDLAFRTGRLEDSTLIARKLGSTHRLLCASHDYLARYGIPEG
CCEEEEEECCHHHHHHHCCHHEEECCCCCCHHHHHHHCCCCCEEEEECCHHHHHCCCCCC
PADLARHRCVIAGPSASGAHWVLDGPQGQETVVVAGRFAANEMQAVAAAALAGFGIAQLP
HHHHHHCEEEEECCCCCCCEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCCHHHCC
QPMADGLINEGRLRRVLDGYTTPAGGLHVLFPSSRHLSPLVKAFIDLAVERISNRANTA
CHHHHCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]