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The map label for this gene is pqqL [C]

Identifier: 13476244

GI number: 13476244

Start: 6201931

End: 6203223

Strand: Reverse

Name: pqqL [C]

Synonym: mll7516

Alternate gene names: 13476244

Gene position: 6203223-6201931 (Counterclockwise)

Preceding gene: 13476245

Following gene: 13476243

Centisome position: 88.16

GC content: 63.73

Gene sequence:

>1293_bases
ATGGGTGTTGAGGTAAGCCGTCTGTCGAACGGCCTGACAGTCGCCACCGAAACCCTTCCAAGTATCGAATCGGTTGCCTT
GGGTGCCTGGGTCAAGTCCGGCGCCCGCAATGAGCGTGATGAAGAGCATGGCATGGCCCACCTGCTCGAGCACATGGCGT
TCAAGGGCACGAAGCGGCGGACGGCCTTCGAAATCGCTTCGGAAATCGAGGATGTCGGTGGCGAGATCAATGCCGCCACC
AGTGTCGAGACCACATCCTACTACGCCAGGGTGCTCAGCGACGACGTGCCGCTGGCCGTCGACATCCTCGCCGACATCCT
GCAGGAGTCCGAATTCGACCCGCAGGAGCTCGAGCGCGAGCAGCACGTCATCCTGCAGGAGATCGGCGCCGCGCACGATA
CGCCAGACGATATCGTCTTCGACCGTTTCACCGAGACGGCCTTTCGCCACCAGACCATAGGGCGCTCGATCCTGGGCACG
CCGGACACCGTCAAATCCTTCACGTCCAAGCAGCTGCACGATTTCATCGAACGCCAATATGGCGCCGAGCGGATGGTGAT
CGTGGCCGCCGGCGACATCAAGCACGACAATTTCGTGCGCGAGGTGGAGAAGCAGCTCGGCGGCTTCCGCAGCAAGGCCG
ACAGCACCATCCCGCAATATGCGCAGTATGTCGGCGGCGATTTCCGCGAGGACCGCGACCTGATGGACGCGCAGATCGTG
CTGGGCTTCGAAGGCCGCGCCTACCACGTGCGCGACTTCTACGCCTCGCAGGTGCTGTCGATGATCCTCGGCGGCGGCAT
GTCGTCGCGCCTGTTCCAGGAAGTCCGCGAGAAACGCGGCCTGTGCTACTCGGTCTATGCCTTCCACTGGGGCTTTTCCG
ACACCGGCATCTTCGGCGTCCACGCCGCGACCGGCCAGAGCGACATCGCCGAACTCGTGCCTGTCATCATCGACGAGTTG
CAGAAGGCCGGCGAGAACATCCTGCAGGAAGAGCTCGACCGTGCGCGCGCCCAGTATCGCGCCGGACTGATCATGTCCGC
CGAAAGCCCGGCCAGCCGCGCCTCGCAGATCGCAAGGCAGCTGCTTTTGTTCGGCAGGCCGATCGCCAAGGAGGAATTGA
TGGAGCGCCTGTCGGCGCTGACGGTGGAGCGGCTGACCGACCTGTCGTCGCGGATGTTCTCGACCAAGCCGACGCTTACC
GCTGTCGGGCCCGTGGGTACGCTGGCACCATATGAGGCGATCCTCGATTCGCTTCCGGGTACGCAGACCACGGCCCGCAG
GCTCGCCGTCTAA

Upstream 100 bases:

>100_bases
CATTTGAGGAAAAATACACGGTACTTCCATCCGACCTGAAAATGGTGGAAGATTATGTCAGCCGCCGTGCGCGAGCGGCG
CGTTAGGGAGTACGAACCAT

Downstream 100 bases:

>100_bases
GCCCCCCAAAGCGCCGTGTTCGCGCTCCCTTTCTTTCGCCGTGACCTGCCGGCGCTGAAGGGCAATCTCGTCACCTTGCG
CGTGCCATACACCAATGACT

Product: processing proteinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MGVEVSRLSNGLTVATETLPSIESVALGAWVKSGARNERDEEHGMAHLLEHMAFKGTKRRTAFEIASEIEDVGGEINAAT
SVETTSYYARVLSDDVPLAVDILADILQESEFDPQELEREQHVILQEIGAAHDTPDDIVFDRFTETAFRHQTIGRSILGT
PDTVKSFTSKQLHDFIERQYGAERMVIVAAGDIKHDNFVREVEKQLGGFRSKADSTIPQYAQYVGGDFREDRDLMDAQIV
LGFEGRAYHVRDFYASQVLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGIFGVHAATGQSDIAELVPVIIDEL
QKAGENILQEELDRARAQYRAGLIMSAESPASRASQIARQLLLFGRPIAKEELMERLSALTVERLTDLSSRMFSTKPTLT
AVGPVGTLAPYEAILDSLPGTQTTARRLAV

Sequences:

>Translated_430_residues
MGVEVSRLSNGLTVATETLPSIESVALGAWVKSGARNERDEEHGMAHLLEHMAFKGTKRRTAFEIASEIEDVGGEINAAT
SVETTSYYARVLSDDVPLAVDILADILQESEFDPQELEREQHVILQEIGAAHDTPDDIVFDRFTETAFRHQTIGRSILGT
PDTVKSFTSKQLHDFIERQYGAERMVIVAAGDIKHDNFVREVEKQLGGFRSKADSTIPQYAQYVGGDFREDRDLMDAQIV
LGFEGRAYHVRDFYASQVLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGIFGVHAATGQSDIAELVPVIIDEL
QKAGENILQEELDRARAQYRAGLIMSAESPASRASQIARQLLLFGRPIAKEELMERLSALTVERLTDLSSRMFSTKPTLT
AVGPVGTLAPYEAILDSLPGTQTTARRLAV
>Mature_429_residues
GVEVSRLSNGLTVATETLPSIESVALGAWVKSGARNERDEEHGMAHLLEHMAFKGTKRRTAFEIASEIEDVGGEINAATS
VETTSYYARVLSDDVPLAVDILADILQESEFDPQELEREQHVILQEIGAAHDTPDDIVFDRFTETAFRHQTIGRSILGTP
DTVKSFTSKQLHDFIERQYGAERMVIVAAGDIKHDNFVREVEKQLGGFRSKADSTIPQYAQYVGGDFREDRDLMDAQIVL
GFEGRAYHVRDFYASQVLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGIFGVHAATGQSDIAELVPVIIDELQ
KAGENILQEELDRARAQYRAGLIMSAESPASRASQIARQLLLFGRPIAKEELMERLSALTVERLTDLSSRMFSTKPTLTA
VGPVGTLAPYEAILDSLPGTQTTARRLAV

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=427, Percent_Identity=31.8501170960187, Blast_Score=240, Evalue=2e-63,
Organism=Homo sapiens, GI46593007, Length=425, Percent_Identity=28.7058823529412, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI24308013, Length=446, Percent_Identity=26.9058295964126, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI50592988, Length=417, Percent_Identity=23.7410071942446, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1787770, Length=178, Percent_Identity=27.5280898876405, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI2367164, Length=188, Percent_Identity=29.2553191489362, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI71999683, Length=403, Percent_Identity=30.5210918114144, Blast_Score=195, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17553678, Length=378, Percent_Identity=26.4550264550265, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17510601, Length=443, Percent_Identity=26.410835214447, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI32566323, Length=412, Percent_Identity=22.3300970873786, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17570205, Length=412, Percent_Identity=22.3300970873786, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17569737, Length=324, Percent_Identity=22.2222222222222, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555260, Length=255, Percent_Identity=22.3529411764706, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=438, Percent_Identity=31.7351598173516, Blast_Score=233, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6321813, Length=414, Percent_Identity=26.5700483091787, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6319426, Length=403, Percent_Identity=22.5806451612903, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325449, Length=198, Percent_Identity=29.2929292929293, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357875, Length=425, Percent_Identity=30.5882352941176, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24646943, Length=425, Percent_Identity=30.5882352941176, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI19921772, Length=463, Percent_Identity=25.7019438444924, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI24665395, Length=430, Percent_Identity=27.4418604651163, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47549; Mature: 47418

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVEVSRLSNGLTVATETLPSIESVALGAWVKSGARNERDEEHGMAHLLEHMAFKGTKRR
CCCCHHHHCCCCEEEHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHH
TAFEIASEIEDVGGEINAATSVETTSYYARVLSDDVPLAVDILADILQESEFDPQELERE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
QHVILQEIGAAHDTPDDIVFDRFTETAFRHQTIGRSILGTPDTVKSFTSKQLHDFIERQY
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHC
GAERMVIVAAGDIKHDNFVREVEKQLGGFRSKADSTIPQYAQYVGGDFREDRDLMDAQIV
CCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCCCHHHHCCEEE
LGFEGRAYHVRDFYASQVLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGIFGV
EECCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEHEECCCCCCCEEEE
HAATGQSDIAELVPVIIDELQKAGENILQEELDRARAQYRAGLIMSAESPASRASQIARQ
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHH
LLLFGRPIAKEELMERLSALTVERLTDLSSRMFSTKPTLTAVGPVGTLAPYEAILDSLPG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCC
TQTTARRLAV
CHHHHHHHCC
>Mature Secondary Structure 
GVEVSRLSNGLTVATETLPSIESVALGAWVKSGARNERDEEHGMAHLLEHMAFKGTKRR
CCCHHHHCCCCEEEHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCHH
TAFEIASEIEDVGGEINAATSVETTSYYARVLSDDVPLAVDILADILQESEFDPQELERE
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHH
QHVILQEIGAAHDTPDDIVFDRFTETAFRHQTIGRSILGTPDTVKSFTSKQLHDFIERQY
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHC
GAERMVIVAAGDIKHDNFVREVEKQLGGFRSKADSTIPQYAQYVGGDFREDRDLMDAQIV
CCCEEEEEEECCCCCHHHHHHHHHHHCCHHHHHCCHHHHHHHHHCCCCCCCHHHHCCEEE
LGFEGRAYHVRDFYASQVLSMILGGGMSSRLFQEVREKRGLCYSVYAFHWGFSDTGIFGV
EECCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEHEECCCCCCCEEEE
HAATGQSDIAELVPVIIDELQKAGENILQEELDRARAQYRAGLIMSAESPASRASQIARQ
ECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHH
LLLFGRPIAKEELMERLSALTVERLTDLSSRMFSTKPTLTAVGPVGTLAPYEAILDSLPG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCC
TQTTARRLAV
CHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA