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The map label for this gene is ygcA [C]

Identifier: 13476218

GI number: 13476218

Start: 6177294

End: 6178532

Strand: Direct

Name: ygcA [C]

Synonym: mlr7480

Alternate gene names: 13476218

Gene position: 6177294-6178532 (Clockwise)

Preceding gene: 13476217

Following gene: 13476219

Centisome position: 87.79

GC content: 65.62

Gene sequence:

>1239_bases
ATGAGCGCGCGCTTCACCGTAAAAAAGCTTGGCGCCCAGGGCGACGGCATTGCCGAGACCGAAAGCGGTGACCTGTTCAT
CCCCTTCACGCTGCCCGGCGAGAGCGTCACCGCAGCGCGCGAACGGGATCGCGCCGCGTTGATGGCAGTGCTGGAGGCCT
CGCTGCTGCGTATCGAGCCCGCCTGCCGCCATTTCACCGAATGCGGCGGCTGCGCCCTCCAGCATTTCGAGGCCGAAGCC
TATCGCCAGTGGAAACGCGACAAGGTGGTGCACGCCCTGAAGGGCATCGATTGCAGCATCGACGAACTGGTCGCCTGCGC
GCCGCACACGCGCCGCCGTGTCGTGCTTGCCGCCCGGCGCAGCGAGACGGGCATGCTGCTCGGCTTCAACCGTCATCTGT
CGCCGGAAATCATTTCCATATCGGAATGCCCGATCTCGCTGCCCGAGATCGTCGCGGCGCTCGACCGGTTGAGGGCGCTC
GCCGATTTGATTTGCGCCACCACCAAATCGTTCCGGATGGCGGTCACCGTGACGGGTTCGGGCCTCGATGTCGCGGTGTA
CGAGTCCGGCAAGCTCGGCGAACACCAGCGCCGCATCGCCTCCAATTTTGTCCTGGCGCAAGGCTTTGCCAGGCTGTCCA
TCGATGACGAGATCATCATCGAACCGAGGAAGCCCGTGGTCATGTTCGGCAGCGTTGCTGTCGCCGTGCCGCCCGGCGCC
TTCCTGCAGGCGACCGAGGCAGCCGAGCAGGCCATGGCCGAGATCGTCGGCACACATCTGAAACGCGCCAAGAAGGTCGC
CGATCTTTTCGCCGGTTGCGGCAGCTTTGCCTTGCGGTTGGCCGCGAAGTCGGAAGTCCATGCGGTGGAGGGCGATGCGG
CGGCTCTCTCGGCGCTTGATCGGGGGGCACGATTCGCGACCGGCCTGAAGCGGGTGACGGGCGAGCGCCGCGACCTGTTC
CGCCGGCCCCTAACGTTCAAGGAGTTGAACACCTTCGACGGCCTTGTCTTCGATCCGCCGCGCGCGGGTGCCGAGGACCA
GTCGAAGCAGATCGCCCGCTCGGATGTTCCCTTCGTTGCCGCGGTGTCCTGCAATCCGGTGACGCTCGCTCGCGACCTGC
GCATCCTCATCGACGGCGGCTATCAAGTGAAGAGCGTGACGCCGATCGACCAGTTCCTGTGGTCGTCCCATGTCGAGGCG
GTCGCCCTGCTGGATAAGCCCAGGAGAAGGCGCGGCTGA

Upstream 100 bases:

>100_bases
TGGATGCAGTTCCCGGCTGGCGTTCGCTCGGCCTGCATCTGTCGCCGATCGAAGGCGGCGACGGCAATCGCGAATTCCTG
CTTGGTGGGATCAAGGATCG

Downstream 100 bases:

>100_bases
GACCGGCCGTGATCACGTTTCGTTGAGGCCGGGCACTTCGGCCTCTCCCGGCCCAAACCGGCCGGATTGACGCCGCAAAG
CCGCCTTCTTGTACCAGCCT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSARFTVKKLGAQGDGIAETESGDLFIPFTLPGESVTAARERDRAALMAVLEASLLRIEPACRHFTECGGCALQHFEAEA
YRQWKRDKVVHALKGIDCSIDELVACAPHTRRRVVLAARRSETGMLLGFNRHLSPEIISISECPISLPEIVAALDRLRAL
ADLICATTKSFRMAVTVTGSGLDVAVYESGKLGEHQRRIASNFVLAQGFARLSIDDEIIIEPRKPVVMFGSVAVAVPPGA
FLQATEAAEQAMAEIVGTHLKRAKKVADLFAGCGSFALRLAAKSEVHAVEGDAAALSALDRGARFATGLKRVTGERRDLF
RRPLTFKELNTFDGLVFDPPRAGAEDQSKQIARSDVPFVAAVSCNPVTLARDLRILIDGGYQVKSVTPIDQFLWSSHVEA
VALLDKPRRRRG

Sequences:

>Translated_412_residues
MSARFTVKKLGAQGDGIAETESGDLFIPFTLPGESVTAARERDRAALMAVLEASLLRIEPACRHFTECGGCALQHFEAEA
YRQWKRDKVVHALKGIDCSIDELVACAPHTRRRVVLAARRSETGMLLGFNRHLSPEIISISECPISLPEIVAALDRLRAL
ADLICATTKSFRMAVTVTGSGLDVAVYESGKLGEHQRRIASNFVLAQGFARLSIDDEIIIEPRKPVVMFGSVAVAVPPGA
FLQATEAAEQAMAEIVGTHLKRAKKVADLFAGCGSFALRLAAKSEVHAVEGDAAALSALDRGARFATGLKRVTGERRDLF
RRPLTFKELNTFDGLVFDPPRAGAEDQSKQIARSDVPFVAAVSCNPVTLARDLRILIDGGYQVKSVTPIDQFLWSSHVEA
VALLDKPRRRRG
>Mature_411_residues
SARFTVKKLGAQGDGIAETESGDLFIPFTLPGESVTAARERDRAALMAVLEASLLRIEPACRHFTECGGCALQHFEAEAY
RQWKRDKVVHALKGIDCSIDELVACAPHTRRRVVLAARRSETGMLLGFNRHLSPEIISISECPISLPEIVAALDRLRALA
DLICATTKSFRMAVTVTGSGLDVAVYESGKLGEHQRRIASNFVLAQGFARLSIDDEIIIEPRKPVVMFGSVAVAVPPGAF
LQATEAAEQAMAEIVGTHLKRAKKVADLFAGCGSFALRLAAKSEVHAVEGDAAALSALDRGARFATGLKRVTGERRDLFR
RPLTFKELNTFDGLVFDPPRAGAEDQSKQIARSDVPFVAAVSCNPVTLARDLRILIDGGYQVKSVTPIDQFLWSSHVEAV
ALLDKPRRRRG

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family

Homologues:

Organism=Escherichia coli, GI1789148, Length=419, Percent_Identity=28.1622911694511, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y7480_RHILO (Q985X9)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_107788.1
- ProteinModelPortal:   Q985X9
- SMR:   Q985X9
- GeneID:   1230443
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr7480
- NMPDR:   fig|266835.1.peg.5889
- HOGENOM:   HBG690163
- OMA:   IISISEC
- InterPro:   IPR016027
- InterPro:   IPR010280

Pfam domain/function: PF05958 tRNA_U5-meth_tr; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 44726; Mature: 44595

Theoretical pI: Translated: 8.50; Mature: 8.50

Prosite motif: PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 364-364 BINDING 243-243 BINDING 270-270 BINDING 290-290 BINDING 338-338

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARFTVKKLGAQGDGIAETESGDLFIPFTLPGESVTAARERDRAALMAVLEASLLRIEP
CCCCEEHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
ACRHFTECGGCALQHFEAEAYRQWKRDKVVHALKGIDCSIDELVACAPHTRRRVVLAARR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEEC
SETGMLLGFNRHLSPEIISISECPISLPEIVAALDRLRALADLICATTKSFRMAVTVTGS
CCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
GLDVAVYESGKLGEHQRRIASNFVLAQGFARLSIDDEIIIEPRKPVVMFGSVAVAVPPGA
CEEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCEEEECCEEEECCCCH
FLQATEAAEQAMAEIVGTHLKRAKKVADLFAGCGSFALRLAAKSEVHAVEGDAAALSALD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHH
RGARFATGLKRVTGERRDLFRRPLTFKELNTFDGLVFDPPRAGAEDQSKQIARSDVPFVA
CCHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCEEE
AVSCNPVTLARDLRILIDGGYQVKSVTPIDQFLWSSHVEAVALLDKPRRRRG
EECCCCEEHCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
SARFTVKKLGAQGDGIAETESGDLFIPFTLPGESVTAARERDRAALMAVLEASLLRIEP
CCCEEHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCH
ACRHFTECGGCALQHFEAEAYRQWKRDKVVHALKGIDCSIDELVACAPHTRRRVVLAARR
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEEEEEEC
SETGMLLGFNRHLSPEIISISECPISLPEIVAALDRLRALADLICATTKSFRMAVTVTGS
CCCCEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECC
GLDVAVYESGKLGEHQRRIASNFVLAQGFARLSIDDEIIIEPRKPVVMFGSVAVAVPPGA
CEEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEECCCCCEEEECCEEEECCCCH
FLQATEAAEQAMAEIVGTHLKRAKKVADLFAGCGSFALRLAAKSEVHAVEGDAAALSALD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHH
RGARFATGLKRVTGERRDLFRRPLTFKELNTFDGLVFDPPRAGAEDQSKQIARSDVPFVA
CCHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCEEE
AVSCNPVTLARDLRILIDGGYQVKSVTPIDQFLWSSHVEAVALLDKPRRRRG
EECCCCEEHCCCEEEEEECCEEEEECCHHHHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968