Click here to switch to the map view.

The map label for this gene is glpD [H]

Identifier: 13476056

GI number: 13476056

Start: 6007918

End: 6009435

Strand: Direct

Name: glpD [H]

Synonym: mlr7270

Alternate gene names: 13476056

Gene position: 6007918-6009435 (Clockwise)

Preceding gene: 13476055

Following gene: 13476057

Centisome position: 85.39

GC content: 65.28

Gene sequence:

>1518_bases
ATGAACGGCGGTCCTGAAATCGTCGACCTCTTCGTCATCGGTGGCGGCGTCAATGGCGCCGGCATTGCGCGCGACGCCGC
CGGCCGCGGACTTTCCGTCATCCTGTGCGAAAAGGACGACCTCGCCGAAGGCACCAGCTCGCGCTCGGGCAAGCTCGTCC
ATGGCGGCCTGCGCTACCTCGAATATTACGAGTTCCGCCTGGTGCGCGAGGCGCTGATCGAGCGCGAGGTGCTGCTAGAA
TCGGCGCCGCACATCATCTGGCCGATGCGCTTCGTGCTACCGCACAGCCCGGACGACCGACCGGCCTGGCTGGTGCGGCT
CGGCCTGTTCCTCTACGACCATCTCGGCGGCCGCAAGCGGCTGCCGGCGACTCGAACGCTGAACCTGCGCACGGCGCCCG
AGGGCGCGCCGATCAAGGATGCCTTCAGGCGCGGCTTCGAATATTCCGACTGCTGGGTCGACGATGCCCGCCTCGTCGTC
ATCAATGCGCTCGACGCGGCCGAGCGCGGCGCCAGGGTTTTCACCCGCACCGCCTGCACCGCCGCCCGCCGTGAGAGCGG
CCTTTGGGTTGTCGAGATGCGGGATGGCAGGACGGGCATCAGGACGGTGGTTCGCGCCCGCGCGCTGATCAATGCCGGCG
GCCCCTGGGTCAACGACATCGTCAACCGCGTTGCCGGCCAGAACTCCACGCGCAATGTGCGCCTGGTCAAGGGCAGCCAC
ATCGTCGTGCCGAAATTCTGGGAAGGGCGGCAGGCCTATCTCATCCAGAACAGCGACAAGCGTGTGATCTTCATCAACCC
TTATCAGAACGATCTCGCCCTGATCGGCACCACCGACATCCCCTATGACGGCCGGCCCGAGGACGTGGCGGCGGATGAGA
GCGAGATCGATTACCTGATCGCGGTGGTCAACCGCTATTTCAAGCGCGGCCTTGCGCGCGGCGATGTCGTCTATTCCTTC
TCCGGCGTCAGGCCGCTCTATGACGACAATGCCGACAACCCAAGTGCGGTGACCCGCGACTATATTTTCGAGCTCGACGC
GCCGGACGCGCAGGCGCCGCTGCTTTCCGTCTTCGGCGGCAAGATCACCACGTTCCGAAAACTGGCCGAGCATGCGCTGG
ACAGGATCGCGCCGTTCTTTCCCCATATGGGCAAGCCCTGGACCGCGAAGGCGCATCTGCCCGGCGGCGACATCGCCAAT
GCCGATTTCGAACAGTTTCTCGGCGACCTCGGAGGCGAATATCCCTGGATGCCGGCATCGCTACTGAAGCACTACGGCAG
GCTCTACGGCACCAGGACGCGGGCCTTGGTTGGCCCGGCGCGTTCGCTCGATGAACTCGGGCGCTGCTTCGGCAAGGATT
TCTTCGAGCGCGAGGCCAATTATCTCTTCGACCGGGAATGGGCGGCGACATCAGCCGATATTCTCGAGCGGCGCACCAAG
CACGGCCTGCATCTGTCCGCCGAGGAGAGGGCGGCCTTCGAGCATTGGTGCGCGAACCGGCTGGCGAGGGCAGGCTGA

Upstream 100 bases:

>100_bases
CGCCGAAGAGGTGCGCCGCTACCTAACCGGCCTGCCTCCGGTCAATCCGTGCTGAGGCAGTGGCCATGACTTTTCAAACC
GGCATCGAGGCCATGGCGAC

Downstream 100 bases:

>100_bases
TGGCGCATTCGGGCGACAACCACTCCAGCGAATTCTGCATGCTGCGCTCCTTGTCCGCCAGCATTGGCGCCGACCCGTTG
CTGGTCCAGGGCGCCGGCGG

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MNGGPEIVDLFVIGGGVNGAGIARDAAGRGLSVILCEKDDLAEGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLE
SAPHIIWPMRFVLPHSPDDRPAWLVRLGLFLYDHLGGRKRLPATRTLNLRTAPEGAPIKDAFRRGFEYSDCWVDDARLVV
INALDAAERGARVFTRTACTAARRESGLWVVEMRDGRTGIRTVVRARALINAGGPWVNDIVNRVAGQNSTRNVRLVKGSH
IVVPKFWEGRQAYLIQNSDKRVIFINPYQNDLALIGTTDIPYDGRPEDVAADESEIDYLIAVVNRYFKRGLARGDVVYSF
SGVRPLYDDNADNPSAVTRDYIFELDAPDAQAPLLSVFGGKITTFRKLAEHALDRIAPFFPHMGKPWTAKAHLPGGDIAN
ADFEQFLGDLGGEYPWMPASLLKHYGRLYGTRTRALVGPARSLDELGRCFGKDFFEREANYLFDREWAATSADILERRTK
HGLHLSAEERAAFEHWCANRLARAG

Sequences:

>Translated_505_residues
MNGGPEIVDLFVIGGGVNGAGIARDAAGRGLSVILCEKDDLAEGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLE
SAPHIIWPMRFVLPHSPDDRPAWLVRLGLFLYDHLGGRKRLPATRTLNLRTAPEGAPIKDAFRRGFEYSDCWVDDARLVV
INALDAAERGARVFTRTACTAARRESGLWVVEMRDGRTGIRTVVRARALINAGGPWVNDIVNRVAGQNSTRNVRLVKGSH
IVVPKFWEGRQAYLIQNSDKRVIFINPYQNDLALIGTTDIPYDGRPEDVAADESEIDYLIAVVNRYFKRGLARGDVVYSF
SGVRPLYDDNADNPSAVTRDYIFELDAPDAQAPLLSVFGGKITTFRKLAEHALDRIAPFFPHMGKPWTAKAHLPGGDIAN
ADFEQFLGDLGGEYPWMPASLLKHYGRLYGTRTRALVGPARSLDELGRCFGKDFFEREANYLFDREWAATSADILERRTK
HGLHLSAEERAAFEHWCANRLARAG
>Mature_505_residues
MNGGPEIVDLFVIGGGVNGAGIARDAAGRGLSVILCEKDDLAEGTSSRSGKLVHGGLRYLEYYEFRLVREALIEREVLLE
SAPHIIWPMRFVLPHSPDDRPAWLVRLGLFLYDHLGGRKRLPATRTLNLRTAPEGAPIKDAFRRGFEYSDCWVDDARLVV
INALDAAERGARVFTRTACTAARRESGLWVVEMRDGRTGIRTVVRARALINAGGPWVNDIVNRVAGQNSTRNVRLVKGSH
IVVPKFWEGRQAYLIQNSDKRVIFINPYQNDLALIGTTDIPYDGRPEDVAADESEIDYLIAVVNRYFKRGLARGDVVYSF
SGVRPLYDDNADNPSAVTRDYIFELDAPDAQAPLLSVFGGKITTFRKLAEHALDRIAPFFPHMGKPWTAKAHLPGGDIAN
ADFEQFLGDLGGEYPWMPASLLKHYGRLYGTRTRALVGPARSLDELGRCFGKDFFEREANYLFDREWAATSADILERRTK
HGLHLSAEERAAFEHWCANRLARAG

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=515, Percent_Identity=31.6504854368932, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI285002231, Length=515, Percent_Identity=31.6504854368932, Blast_Score=193, Evalue=3e-49,
Organism=Escherichia coli, GI2367226, Length=469, Percent_Identity=50.1066098081023, Blast_Score=488, Evalue=1e-139,
Organism=Escherichia coli, GI1788574, Length=383, Percent_Identity=26.6318537859008, Blast_Score=90, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17509253, Length=508, Percent_Identity=30.1181102362205, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI115534726, Length=503, Percent_Identity=28.8270377733598, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6322036, Length=452, Percent_Identity=30.3097345132743, Blast_Score=162, Evalue=9e-41,
Organism=Drosophila melanogaster, GI161077125, Length=518, Percent_Identity=31.0810810810811, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653942, Length=518, Percent_Identity=31.0810810810811, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24653944, Length=518, Percent_Identity=31.0810810810811, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI20130025, Length=518, Percent_Identity=31.0810810810811, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24586295, Length=385, Percent_Identity=29.0909090909091, Blast_Score=120, Evalue=3e-27,
Organism=Drosophila melanogaster, GI19921278, Length=492, Percent_Identity=24.5934959349593, Blast_Score=109, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56381; Mature: 56381

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00977 FAD_G3PDH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGGPEIVDLFVIGGGVNGAGIARDAAGRGLSVILCEKDDLAEGTSSRSGKLVHGGLRYL
CCCCCCEEEEEEEECCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHH
EYYEFRLVREALIEREVLLESAPHIIWPMRFVLPHSPDDRPAWLVRLGLFLYDHLGGRKR
HHHHHHHHHHHHHHHHHHHHCCCCEEECHHEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
LPATRTLNLRTAPEGAPIKDAFRRGFEYSDCWVDDARLVVINALDAAERGARVFTRTACT
CCCCEEEEEEECCCCCCHHHHHHCCCCCCCCEECCCEEEEEEEHHHHHHCCHHHHHHHHH
AARRESGLWVVEMRDGRTGIRTVVRARALINAGGPWVNDIVNRVAGQNSTRNVRLVKGSH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCE
IVVPKFWEGRQAYLIQNSDKRVIFINPYQNDLALIGTTDIPYDGRPEDVAADESEIDYLI
EEEECCCCCCEEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHH
AVVNRYFKRGLARGDVVYSFSGVRPLYDDNADNPSAVTRDYIFELDAPDAQAPLLSVFGG
HHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHEEEECCCCCCCCHHHHHCC
KITTFRKLAEHALDRIAPFFPHMGKPWTAKAHLPGGDIANADFEQFLGDLGGEYPWMPAS
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHH
LLKHYGRLYGTRTRALVGPARSLDELGRCFGKDFFEREANYLFDREWAATSADILERRTK
HHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCHHHHHHHHHHEECCCCCCCHHHHHHHHHH
HGLHLSAEERAAFEHWCANRLARAG
CCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNGGPEIVDLFVIGGGVNGAGIARDAAGRGLSVILCEKDDLAEGTSSRSGKLVHGGLRYL
CCCCCCEEEEEEEECCCCCCCCCHHCCCCCCEEEEECCCCCCCCCCCCCCCEEEHHHHHH
EYYEFRLVREALIEREVLLESAPHIIWPMRFVLPHSPDDRPAWLVRLGLFLYDHLGGRKR
HHHHHHHHHHHHHHHHHHHHCCCCEEECHHEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
LPATRTLNLRTAPEGAPIKDAFRRGFEYSDCWVDDARLVVINALDAAERGARVFTRTACT
CCCCEEEEEEECCCCCCHHHHHHCCCCCCCCEECCCEEEEEEEHHHHHHCCHHHHHHHHH
AARRESGLWVVEMRDGRTGIRTVVRARALINAGGPWVNDIVNRVAGQNSTRNVRLVKGSH
HHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEECCE
IVVPKFWEGRQAYLIQNSDKRVIFINPYQNDLALIGTTDIPYDGRPEDVAADESEIDYLI
EEEECCCCCCEEEEEECCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHH
AVVNRYFKRGLARGDVVYSFSGVRPLYDDNADNPSAVTRDYIFELDAPDAQAPLLSVFGG
HHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHEEEECCCCCCCCHHHHHCC
KITTFRKLAEHALDRIAPFFPHMGKPWTAKAHLPGGDIANADFEQFLGDLGGEYPWMPAS
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHH
LLKHYGRLYGTRTRALVGPARSLDELGRCFGKDFFEREANYLFDREWAATSADILERRTK
HHHHHHHHHCCCHHHHHCCHHHHHHHHHHHCHHHHHHHHHHEECCCCCCCHHHHHHHHHH
HGLHLSAEERAAFEHWCANRLARAG
CCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]