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The map label for this gene is puuB [H]

Identifier: 13475918

GI number: 13475918

Start: 5861411

End: 5862694

Strand: Reverse

Name: puuB [H]

Synonym: mll7103

Alternate gene names: 13475918

Gene position: 5862694-5861411 (Counterclockwise)

Preceding gene: 13475919

Following gene: 13475916

Centisome position: 83.32

GC content: 66.2

Gene sequence:

>1284_bases
ATGCTTGAGAGCAACCCTCCGAAAAGCCTCTATCGCGAAACGGCCGGCGGCATCGGCGATTACTGCGCCCTTGCCGGCGC
GCAGCGGGCAAGGGTCGCCATTGTCGGCGGCGGCTTCACGGGGCTTTCCACCGCCTTGCATCTGGCGGAGGCCGGCGACG
ACGTCGCCGTGCTCGAGGCCCAACAGCCGGGCTGGGGTGCGTCGGGCAGGAATGGCGGCCAGGTCAATCCCGGCCTCAAA
TACGATCCCGACACGATCGAGGCGATGTTCGGCCCAGAGCTTGGGCCGCGGATGATCGATTTTTCCTACGGCGCGCCGGA
TTTCACCTTCGGCCTCATCAAGCGCCTGTCGATCGCCTGCGATGCCCGGCAGAACGGCACCATACGCGCGGCCATCCGGC
CGAAGCCGCAAGCCGCGGTGCGGACCACGGCCGCGCAATGCCAGCGGCGGGGCATGCCGGTCAGCATGGTGGATGCACAG
GCGATGGCGACACGAACCGGTACCGGCAGATACATAGCCGGCATGTTCGACGCCCGCGGCGGCGACCTCCATCCCCTGAA
ATACACGATTGGCCTGGCAGCCGCCGCGCGGAACGCCAGCGCGCGGATTTTCGGTGGCAGCGAAGTGCTTTCGCTGAAGA
GAGAGGCTGGACGATGGGTCCTCAAAACCGCCAACGGCTCGGTCAGCGCCGAGAAGGTGCTTGTCGCGACCAATGGCTAT
ACCGGAGCCCTGTGGCCGGGCCTGGAGCAATCCCTGGTTCCGGTGTTCAGCGCGATCGCCGCGACCGAGCCGCTTGCGCC
GGCGGCCGCGGCTCAAATTCTCCCCGACAGGCCTGTCCTCTACGAAGCCGGCAACATCACCGTCTACTATCGCATCGACG
CGCAGAACCGCCTTCTCATGGGCGGCCGCGGACCGATGAAGCCGATCGGTGATGCTTCCGCCATCCGCTACCTCACCGAC
TATGCGTTGCGGCTGTGGCCGGCACTCGCCGGAGTACGCTGGACACATGGCTGGAACGGCCGGGTCGCGATCACCAAGGA
CCATCTTCTGCACATTCACGAGCCGGAGGACGGCGTGCTGATCTGCCTAGGCTACAATGGCCGTGGCGTCGCCATGGCCT
CGGCGATGGGTGCTGCCCTGGCGCAGCGGTTGCAAGGCCGCGAGACCTCGCCGTTTCCCATGCCAATATCGCCGCTCAAG
CCAATCCGGTTTCACCGCTTCTGGCCGCTCGGAGTGAAGGCGGCGATCCTGTCGGGGCGGTTGAAGGATCGCTTCGGCCT
TTGA

Upstream 100 bases:

>100_bases
ATGGAGTTTTCGCAGGTGGCGCATCCCCTTTCGCCCAACGGCTCCCGTCCAGCCTCTCGGGCCTGTGTGTTTCTCCCCGG
TCACTTTGACGATGCCCAGT

Downstream 100 bases:

>100_bases
TGCAAAGCGTTCGACCGACCTGACGGCTCGTGAGGTTGGAAAAGCTGCTCCTAACTAGCGATACTGCGGAAACGCAACCC
CCGCCGGCGCGTTGGCCCAG

Product: oxidoreductase

Products: NA

Alternate protein names: Gamma-Glu-Put oxidase; Gamma-glutamylputrescine oxidase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MLESNPPKSLYRETAGGIGDYCALAGAQRARVAIVGGGFTGLSTALHLAEAGDDVAVLEAQQPGWGASGRNGGQVNPGLK
YDPDTIEAMFGPELGPRMIDFSYGAPDFTFGLIKRLSIACDARQNGTIRAAIRPKPQAAVRTTAAQCQRRGMPVSMVDAQ
AMATRTGTGRYIAGMFDARGGDLHPLKYTIGLAAAARNASARIFGGSEVLSLKREAGRWVLKTANGSVSAEKVLVATNGY
TGALWPGLEQSLVPVFSAIAATEPLAPAAAAQILPDRPVLYEAGNITVYYRIDAQNRLLMGGRGPMKPIGDASAIRYLTD
YALRLWPALAGVRWTHGWNGRVAITKDHLLHIHEPEDGVLICLGYNGRGVAMASAMGAALAQRLQGRETSPFPMPISPLK
PIRFHRFWPLGVKAAILSGRLKDRFGL

Sequences:

>Translated_427_residues
MLESNPPKSLYRETAGGIGDYCALAGAQRARVAIVGGGFTGLSTALHLAEAGDDVAVLEAQQPGWGASGRNGGQVNPGLK
YDPDTIEAMFGPELGPRMIDFSYGAPDFTFGLIKRLSIACDARQNGTIRAAIRPKPQAAVRTTAAQCQRRGMPVSMVDAQ
AMATRTGTGRYIAGMFDARGGDLHPLKYTIGLAAAARNASARIFGGSEVLSLKREAGRWVLKTANGSVSAEKVLVATNGY
TGALWPGLEQSLVPVFSAIAATEPLAPAAAAQILPDRPVLYEAGNITVYYRIDAQNRLLMGGRGPMKPIGDASAIRYLTD
YALRLWPALAGVRWTHGWNGRVAITKDHLLHIHEPEDGVLICLGYNGRGVAMASAMGAALAQRLQGRETSPFPMPISPLK
PIRFHRFWPLGVKAAILSGRLKDRFGL
>Mature_427_residues
MLESNPPKSLYRETAGGIGDYCALAGAQRARVAIVGGGFTGLSTALHLAEAGDDVAVLEAQQPGWGASGRNGGQVNPGLK
YDPDTIEAMFGPELGPRMIDFSYGAPDFTFGLIKRLSIACDARQNGTIRAAIRPKPQAAVRTTAAQCQRRGMPVSMVDAQ
AMATRTGTGRYIAGMFDARGGDLHPLKYTIGLAAAARNASARIFGGSEVLSLKREAGRWVLKTANGSVSAEKVLVATNGY
TGALWPGLEQSLVPVFSAIAATEPLAPAAAAQILPDRPVLYEAGNITVYYRIDAQNRLLMGGRGPMKPIGDASAIRYLTD
YALRLWPALAGVRWTHGWNGRVAITKDHLLHIHEPEDGVLICLGYNGRGVAMASAMGAALAQRLQGRETSPFPMPISPLK
PIRFHRFWPLGVKAAILSGRLKDRFGL

Specific function: Involved in the breakdown of putrescine via the oxidation of L-glutamylputrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI24797151, Length=283, Percent_Identity=26.8551236749117, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1787559, Length=425, Percent_Identity=32, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 45427; Mature: 45427

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLESNPPKSLYRETAGGIGDYCALAGAQRARVAIVGGGFTGLSTALHLAEAGDDVAVLEA
CCCCCCCHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEE
QQPGWGASGRNGGQVNPGLKYDPDTIEAMFGPELGPRMIDFSYGAPDFTFGLIKRLSIAC
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
DARQNGTIRAAIRPKPQAAVRTTAAQCQRRGMPVSMVDAQAMATRTGTGRYIAGMFDARG
CCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCCCCEEEEEEECCC
GDLHPLKYTIGLAAAARNASARIFGGSEVLSLKREAGRWVLKTANGSVSAEKVLVATNGY
CCCCCEEEEEEEHHHCCCCCEEEECCHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCC
TGALWPGLEQSLVPVFSAIAATEPLAPAAAAQILPDRPVLYEAGNITVYYRIDAQNRLLM
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCEEEEEEECCCCEEEE
GGRGPMKPIGDASAIRYLTDYALRLWPALAGVRWTHGWNGRVAITKDHLLHIHEPEDGVL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCEEEEECCCCCEE
ICLGYNGRGVAMASAMGAALAQRLQGRETSPFPMPISPLKPIRFHRFWPLGVKAAILSGR
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCC
LKDRFGL
HHHHCCC
>Mature Secondary Structure
MLESNPPKSLYRETAGGIGDYCALAGAQRARVAIVGGGFTGLSTALHLAEAGDDVAVLEA
CCCCCCCHHHHHHHCCCCHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHCCCCEEEEEE
QQPGWGASGRNGGQVNPGLKYDPDTIEAMFGPELGPRMIDFSYGAPDFTFGLIKRLSIAC
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHC
DARQNGTIRAAIRPKPQAAVRTTAAQCQRRGMPVSMVDAQAMATRTGTGRYIAGMFDARG
CCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEEECHHHHHCCCCCCCEEEEEEECCC
GDLHPLKYTIGLAAAARNASARIFGGSEVLSLKREAGRWVLKTANGSVSAEKVLVATNGY
CCCCCEEEEEEEHHHCCCCCEEEECCHHHHHHHHHCCCEEEEECCCCCCEEEEEEEECCC
TGALWPGLEQSLVPVFSAIAATEPLAPAAAAQILPDRPVLYEAGNITVYYRIDAQNRLLM
CCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCEEEECCCEEEEEEECCCCEEEE
GGRGPMKPIGDASAIRYLTDYALRLWPALAGVRWTHGWNGRVAITKDHLLHIHEPEDGVL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCEEEEECCCCCEE
ICLGYNGRGVAMASAMGAALAQRLQGRETSPFPMPISPLKPIRFHRFWPLGVKAAILSGR
EEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHCC
LKDRFGL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1840553; 7984428 [H]