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The map label for this gene is dgoD [H]

Identifier: 13475903

GI number: 13475903

Start: 5847312

End: 5848484

Strand: Reverse

Name: dgoD [H]

Synonym: mll7085

Alternate gene names: 13475903

Gene position: 5848484-5847312 (Counterclockwise)

Preceding gene: 13475905

Following gene: 13475902

Centisome position: 83.12

GC content: 64.62

Gene sequence:

>1173_bases
ATGAAAATTACGGCCATCAAGGCGCTCGTCTGCAACGCGGAAATGCGCAACTGGGTTTTTGTTCGGGTCGAAACCGATGA
GCCCGGTCTGTTTGGCTGGGGCGAGGCAACGCTGGAATGGAAGACGCGTGCCGTCGTTGGCGCGCTTCAGGATCTTGAGG
CATTGCTCATCGGGCAGGACCCGCGCAATGTGGAGCAGTGCTACCAGATCCTTACCCGCCACGGCTTCTGGCGTCTCGGG
GTCGAGGGAATGTCGGCCGTCAGCGGCATCGAGATCGCGCTCTGGGACATTCTGGGCAAGTCGCTGGGTGTCCCCGTCTG
GCGGCTTCTCGGCGGCCAGGTCCGCGACTATCTGCGCACCTATACGCATCTCGGCCTCGGCGACATGAAGGCGGTCTATG
AGAGCGGGTCGGCGGACACGATCGTCGAACGCGGGCGCATCGTCACGCAGGCCGGCTACGACGCCGTCAAGGTCGTCTGC
ATTCCCTACACCCACTATGTCTCGCCGGCGAAGGCGGTCGATTCCGTTGCCGACATGGTTGGCGCGCTGCGCGAGGCCGT
CGGTCCCGATATCGACATCATGGTCGACTTTCACGGACGCCCGGCCTCCGTCAACGCGGCAATGGACTATCTCAAGGCGA
TCGAACCGGCCCGCATCATGTTCGCCGAAGAGCCGGTACCGCCGGAAGATGTCGCCGGCCTGGCGCATATCACCGCGCGA
TCGGCGATCCCCATCGCGTCCGGCGAGCGGCTGATCGGGCGCCGCGAATTCACGCAATCGGTTGCGGCGCGCGCCTTTAA
CATTGCCCAGCCCGATATCTGCCATACTGGCGGTCTGCTCGAGACCAAGAAGATCGCGGCTCTGGCCGAAACCGCCGGCA
TCGGCCTTGCGCCGCACAACCCGCTCGGCCCGATCGCCGGCGTCGCAGCGCTTCACTTCGGCATATCGACACCGAACGTC
ATCATCCAGGAGGAGATGTCGGGCGCGGTCGCCTGGTACGACGACGTCGTCACCTGGCCGATCGATCGCAAGCCCGGCCG
CTGGGACGTGCCCGATCTGCCGGGCCTTGGCGTCACCGTGAATGAAGATGTCATCGCGCGCCACCCCTTCAAGCAGGAAG
TCCTGCATGCCCGCAACGCCGTCATGCCCGACGGCACCGTGGTCGATTGGTGA

Upstream 100 bases:

>100_bases
CGAAGCCGGGGCAGCCCTATGCCGCGCTTGACTTGCTCATATTATTCATAATAAATCATACATAATAACGGTAAAAAAGA
CGACACATCTGGGAGCACCT

Downstream 100 bases:

>100_bases
GCGCCATGACAGGCAGGCTTCAGGGGAAGATCGCAATCGTCACCGGCGCCGGCCAGGGCATTGGTGCAGCCACTGCCCGG
GCCTTTGCGATGCAGGGAGC

Product: 2-oxo-3-deoxygalactonate 6-phosphate aldolase and galactonate dehydratase

Products: NA

Alternate protein names: GalD [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MKITAIKALVCNAEMRNWVFVRVETDEPGLFGWGEATLEWKTRAVVGALQDLEALLIGQDPRNVEQCYQILTRHGFWRLG
VEGMSAVSGIEIALWDILGKSLGVPVWRLLGGQVRDYLRTYTHLGLGDMKAVYESGSADTIVERGRIVTQAGYDAVKVVC
IPYTHYVSPAKAVDSVADMVGALREAVGPDIDIMVDFHGRPASVNAAMDYLKAIEPARIMFAEEPVPPEDVAGLAHITAR
SAIPIASGERLIGRREFTQSVAARAFNIAQPDICHTGGLLETKKIAALAETAGIGLAPHNPLGPIAGVAALHFGISTPNV
IIQEEMSGAVAWYDDVVTWPIDRKPGRWDVPDLPGLGVTVNEDVIARHPFKQEVLHARNAVMPDGTVVDW

Sequences:

>Translated_390_residues
MKITAIKALVCNAEMRNWVFVRVETDEPGLFGWGEATLEWKTRAVVGALQDLEALLIGQDPRNVEQCYQILTRHGFWRLG
VEGMSAVSGIEIALWDILGKSLGVPVWRLLGGQVRDYLRTYTHLGLGDMKAVYESGSADTIVERGRIVTQAGYDAVKVVC
IPYTHYVSPAKAVDSVADMVGALREAVGPDIDIMVDFHGRPASVNAAMDYLKAIEPARIMFAEEPVPPEDVAGLAHITAR
SAIPIASGERLIGRREFTQSVAARAFNIAQPDICHTGGLLETKKIAALAETAGIGLAPHNPLGPIAGVAALHFGISTPNV
IIQEEMSGAVAWYDDVVTWPIDRKPGRWDVPDLPGLGVTVNEDVIARHPFKQEVLHARNAVMPDGTVVDW
>Mature_390_residues
MKITAIKALVCNAEMRNWVFVRVETDEPGLFGWGEATLEWKTRAVVGALQDLEALLIGQDPRNVEQCYQILTRHGFWRLG
VEGMSAVSGIEIALWDILGKSLGVPVWRLLGGQVRDYLRTYTHLGLGDMKAVYESGSADTIVERGRIVTQAGYDAVKVVC
IPYTHYVSPAKAVDSVADMVGALREAVGPDIDIMVDFHGRPASVNAAMDYLKAIEPARIMFAEEPVPPEDVAGLAHITAR
SAIPIASGERLIGRREFTQSVAARAFNIAQPDICHTGGLLETKKIAALAETAGIGLAPHNPLGPIAGVAALHFGISTPNV
IIQEEMSGAVAWYDDVVTWPIDRKPGRWDVPDLPGLGVTVNEDVIARHPFKQEVLHARNAVMPDGTVVDW

Specific function: Catalyzes the dehydration of D-galactonate to 2-keto-3- deoxy-D-galactonate [H]

COG id: COG4948

COG function: function code MR; L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GalD subfamily [H]

Homologues:

Organism=Homo sapiens, GI42544119, Length=396, Percent_Identity=23.989898989899, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI48994953, Length=398, Percent_Identity=36.6834170854271, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787864, Length=411, Percent_Identity=28.9537712895377, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI226510960, Length=300, Percent_Identity=26.6666666666667, Blast_Score=85, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018110
- InterPro:   IPR013342
- InterPro:   IPR013341
- InterPro:   IPR001354 [H]

Pfam domain/function: PF01188 MR_MLE; PF02746 MR_MLE_N [H]

EC number: =4.2.1.6 [H]

Molecular weight: Translated: 42307; Mature: 42307

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00908 MR_MLE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITAIKALVCNAEMRNWVFVRVETDEPGLFGWGEATLEWKTRAVVGALQDLEALLIGQD
CCEEHEEHHHHCCCCCCEEEEEEECCCCCEEECCCCEEEHHHHHHHHHHHHHHHEEECCC
PRNVEQCYQILTRHGFWRLGVEGMSAVSGIEIALWDILGKSLGVPVWRLLGGQVRDYLRT
CCCHHHHHHHHHHCCCEEECCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
YTHLGLGDMKAVYESGSADTIVERGRIVTQAGYDAVKVVCIPYTHYVSPAKAVDSVADMV
HHHCCCCHHHHHHHCCCCHHHHHCCEEEEECCCCEEEEEEEECHHHCCHHHHHHHHHHHH
GALREAVGPDIDIMVDFHGRPASVNAAMDYLKAIEPARIMFAEEPVPPEDVAGLAHITAR
HHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHH
SAIPIASGERLIGRREFTQSVAARAFNIAQPDICHTGGLLETKKIAALAETAGIGLAPHN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
PLGPIAGVAALHFGISTPNVIIQEEMSGAVAWYDDVVTWPIDRKPGRWDVPDLPGLGVTV
CCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCEEECCCCCCCCCCCCCCCCCCCEEE
NEDVIARHPFKQEVLHARNAVMPDGTVVDW
CCCHHHCCCHHHHHHHHHCCCCCCCCEECC
>Mature Secondary Structure
MKITAIKALVCNAEMRNWVFVRVETDEPGLFGWGEATLEWKTRAVVGALQDLEALLIGQD
CCEEHEEHHHHCCCCCCEEEEEEECCCCCEEECCCCEEEHHHHHHHHHHHHHHHEEECCC
PRNVEQCYQILTRHGFWRLGVEGMSAVSGIEIALWDILGKSLGVPVWRLLGGQVRDYLRT
CCCHHHHHHHHHHCCCEEECCCHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
YTHLGLGDMKAVYESGSADTIVERGRIVTQAGYDAVKVVCIPYTHYVSPAKAVDSVADMV
HHHCCCCHHHHHHHCCCCHHHHHCCEEEEECCCCEEEEEEEECHHHCCHHHHHHHHHHHH
GALREAVGPDIDIMVDFHGRPASVNAAMDYLKAIEPARIMFAEEPVPPEDVAGLAHITAR
HHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHEEEECCCCCHHHHHHHHHHHHH
SAIPIASGERLIGRREFTQSVAARAFNIAQPDICHTGGLLETKKIAALAETAGIGLAPHN
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
PLGPIAGVAALHFGISTPNVIIQEEMSGAVAWYDDVVTWPIDRKPGRWDVPDLPGLGVTV
CCCHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCEEECCCCCCCCCCCCCCCCCCCEEE
NEDVIARHPFKQEVLHARNAVMPDGTVVDW
CCCHHHCCCHHHHHHHHHCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA