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The map label for this gene is betA [H]

Identifier: 13475668

GI number: 13475668

Start: 5590930

End: 5592561

Strand: Direct

Name: betA [H]

Synonym: mlr6792

Alternate gene names: 13475668

Gene position: 5590930-5592561 (Clockwise)

Preceding gene: 13475667

Following gene: 13475669

Centisome position: 79.46

GC content: 64.4

Gene sequence:

>1632_bases
ATGCCGCACGCGGAAAGTTACGACTATATCATCGTTGGGGCCGGATCGGCCGGTTGCGTGCTCGCCAACCGGCTGAGCGC
CGATCCGAGATGTTCGGTGCTGCTGCTGGAGGCCGGCGGCTGGGATCGCGATCCCATGATCCACATTCCGCTTGGATGGG
GCAAGATCCTGACCGAGCGCCGCCATGACTGGATGTATTTCTGCGAGCCGGAAGACAATGTCGGCGGACGCCGGGTCGAG
TGCGCGCGCGGCAAGGTCATTGGCGGATCGTCGTCGACCAACGCCATGGCCTATGTGCGGGGAAATCGCGGCGACTATGA
TCGTTGGGCAGCGACAGGGCTCAGCGAGTGGTCATACGACAAGGTCCTACCGTACTTCCGCAAGCAGGAGAGCTGGGAAG
GGGGCGCGAACCAGTATCGCGGCGGCAATGGCCCGGTCAGCACCCAGTTCTGCCGCTACAAGGACACGCTGATCGACGCC
TTCGCGCAAGCCAGCGTGCAGGCAGGCTATGCGCAGACGAAGGACTATAATGGCGAGCGGCAGGAAGGTTTCGGCCGCCT
CCAGATGACGATTTCAAAAGGTCGGCGCGCCTCGACCGCGTCAGCCTATCTGCGGCCGGTGCTGAAGCGGCCCAACCTGA
CCGTTCTGACGGAAGCGAGCGCGACCAGGATCGTGCTGGAGGGTGCGCGCGCCACCGGCGTCACCATCAACCATCGCGGC
GGCGAACGTACGGTTCTCGCCCGCAAGGAAGTGCTGCTTGCCGGCGGCGTGATCAACACGCCGCAACTGATGATGCTGTC
GGGTATCGGGGCGCAGGATGAGCTTGCCGCGCACGGTGTCCAGACGCGGGTCAATCTGCCGGCGGTCGGCAAGAACCTGC
AAGATCACGTCTCGGTCATTCTCATGTACCGGCGCCGGGCTCCGGGCGGCCCCTTCCTGCGCAACATGCGTGCCGATCGC
ATCGGCTTCGATTTCGTCAAGACCTACCTGACGGGACGCGGTTTCTCTGGCGATGTGCCCGGCGGGGTTGTCGCCTTCCT
CAAGAGCGGTCCGGCGCGACCCTTGCCGGATGTGCAACTGCTCTTCACGGCGGCGCCGCTCGCGGCATGGCCATACTTCA
AGCCGTTCAAGGCGCCGTTTGCGGACGGCTTCGCGACACGGATCGTAGCGACACAGCCCGAAAGCCGGGGAGCGGTGAAA
CTGGCCTCGGCCGATCCTTCCGCGGCGCCCCTGATCCACCAGAATTTCCTCGCGTCGCCCAAGGATTGGGAGTCGCTGCG
GGCCGGTTTCCGTGTGGCAAGGGATCTGGCCGCGCAGCCCTCCATGCAACCCTTCATCGAGGCGGAGTTCTTTCCCGGCC
CGAAGTGCCAGAGCGACGACGAGATCGACGAGCATATCCGCAAGACCTCCATCACCGTGCATCACCCGGCCGGGACCTGC
AGGATGGGGGCGGATGCGGCCTCGGTCGTCGACCCGCAATTGCGGGTTCGCGGCGTCGATAGGCTTAGAGTGGTGGACGC
TTCCGTCATGCCCGACCTGGTCTGCGGAAACATCAACGCGGCAGTGATCATGATTGCCGAAAAGGCCGCCGACCTCATCG
CGAGCTCAAAAGAAGGCAGGGCAGTGCAATGA

Upstream 100 bases:

>100_bases
CTTTGAACATCAGCTGGGAAGCCTGGTGTCGGCCAGGACTTTCCAGCCTCAATCGCACTAGTTCTCTGGCGCCGGGGCGT
CGGACGAAAGCAATGAAACC

Downstream 100 bases:

>100_bases
TCCGAAATATCGCCATCATCGGCCTGGGTACGATGGGGCCGGGCATGGCCGCCCGGCTCGCCAGAGGCGGCCTGCAGGTG
GTCGCCTACGATGTTGCCCC

Product: dehydrogenase

Products: NA

Alternate protein names: CDH; CHD [H]

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MPHAESYDYIIVGAGSAGCVLANRLSADPRCSVLLLEAGGWDRDPMIHIPLGWGKILTERRHDWMYFCEPEDNVGGRRVE
CARGKVIGGSSSTNAMAYVRGNRGDYDRWAATGLSEWSYDKVLPYFRKQESWEGGANQYRGGNGPVSTQFCRYKDTLIDA
FAQASVQAGYAQTKDYNGERQEGFGRLQMTISKGRRASTASAYLRPVLKRPNLTVLTEASATRIVLEGARATGVTINHRG
GERTVLARKEVLLAGGVINTPQLMMLSGIGAQDELAAHGVQTRVNLPAVGKNLQDHVSVILMYRRRAPGGPFLRNMRADR
IGFDFVKTYLTGRGFSGDVPGGVVAFLKSGPARPLPDVQLLFTAAPLAAWPYFKPFKAPFADGFATRIVATQPESRGAVK
LASADPSAAPLIHQNFLASPKDWESLRAGFRVARDLAAQPSMQPFIEAEFFPGPKCQSDDEIDEHIRKTSITVHHPAGTC
RMGADAASVVDPQLRVRGVDRLRVVDASVMPDLVCGNINAAVIMIAEKAADLIASSKEGRAVQ

Sequences:

>Translated_543_residues
MPHAESYDYIIVGAGSAGCVLANRLSADPRCSVLLLEAGGWDRDPMIHIPLGWGKILTERRHDWMYFCEPEDNVGGRRVE
CARGKVIGGSSSTNAMAYVRGNRGDYDRWAATGLSEWSYDKVLPYFRKQESWEGGANQYRGGNGPVSTQFCRYKDTLIDA
FAQASVQAGYAQTKDYNGERQEGFGRLQMTISKGRRASTASAYLRPVLKRPNLTVLTEASATRIVLEGARATGVTINHRG
GERTVLARKEVLLAGGVINTPQLMMLSGIGAQDELAAHGVQTRVNLPAVGKNLQDHVSVILMYRRRAPGGPFLRNMRADR
IGFDFVKTYLTGRGFSGDVPGGVVAFLKSGPARPLPDVQLLFTAAPLAAWPYFKPFKAPFADGFATRIVATQPESRGAVK
LASADPSAAPLIHQNFLASPKDWESLRAGFRVARDLAAQPSMQPFIEAEFFPGPKCQSDDEIDEHIRKTSITVHHPAGTC
RMGADAASVVDPQLRVRGVDRLRVVDASVMPDLVCGNINAAVIMIAEKAADLIASSKEGRAVQ
>Mature_542_residues
PHAESYDYIIVGAGSAGCVLANRLSADPRCSVLLLEAGGWDRDPMIHIPLGWGKILTERRHDWMYFCEPEDNVGGRRVEC
ARGKVIGGSSSTNAMAYVRGNRGDYDRWAATGLSEWSYDKVLPYFRKQESWEGGANQYRGGNGPVSTQFCRYKDTLIDAF
AQASVQAGYAQTKDYNGERQEGFGRLQMTISKGRRASTASAYLRPVLKRPNLTVLTEASATRIVLEGARATGVTINHRGG
ERTVLARKEVLLAGGVINTPQLMMLSGIGAQDELAAHGVQTRVNLPAVGKNLQDHVSVILMYRRRAPGGPFLRNMRADRI
GFDFVKTYLTGRGFSGDVPGGVVAFLKSGPARPLPDVQLLFTAAPLAAWPYFKPFKAPFADGFATRIVATQPESRGAVKL
ASADPSAAPLIHQNFLASPKDWESLRAGFRVARDLAAQPSMQPFIEAEFFPGPKCQSDDEIDEHIRKTSITVHHPAGTCR
MGADAASVVDPQLRVRGVDRLRVVDASVMPDLVCGNINAAVIMIAEKAADLIASSKEGRAVQ

Specific function: Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=544, Percent_Identity=42.2794117647059, Blast_Score=403, Evalue=1e-112,
Organism=Escherichia coli, GI1786503, Length=539, Percent_Identity=41.9294990723562, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17532301, Length=556, Percent_Identity=38.1294964028777, Blast_Score=368, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642055, Length=568, Percent_Identity=37.3239436619718, Blast_Score=330, Evalue=2e-90,
Organism=Drosophila melanogaster, GI24642042, Length=565, Percent_Identity=38.4070796460177, Blast_Score=325, Evalue=4e-89,
Organism=Drosophila melanogaster, GI24642048, Length=567, Percent_Identity=37.2134038800705, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI24642037, Length=580, Percent_Identity=38.9655172413793, Blast_Score=313, Evalue=2e-85,
Organism=Drosophila melanogaster, GI24650267, Length=568, Percent_Identity=36.9718309859155, Blast_Score=309, Evalue=3e-84,
Organism=Drosophila melanogaster, GI45549471, Length=570, Percent_Identity=37.719298245614, Blast_Score=308, Evalue=4e-84,
Organism=Drosophila melanogaster, GI45551458, Length=567, Percent_Identity=37.3897707231041, Blast_Score=308, Evalue=6e-84,
Organism=Drosophila melanogaster, GI24642039, Length=571, Percent_Identity=37.4781085814361, Blast_Score=307, Evalue=9e-84,
Organism=Drosophila melanogaster, GI18859995, Length=572, Percent_Identity=37.7622377622378, Blast_Score=305, Evalue=7e-83,
Organism=Drosophila melanogaster, GI24642035, Length=575, Percent_Identity=36.8695652173913, Blast_Score=304, Evalue=1e-82,
Organism=Drosophila melanogaster, GI24642059, Length=576, Percent_Identity=36.1111111111111, Blast_Score=291, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24642051, Length=581, Percent_Identity=32.7022375215146, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI17137792, Length=548, Percent_Identity=34.6715328467153, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI18859993, Length=586, Percent_Identity=33.1058020477816, Blast_Score=260, Evalue=2e-69,
Organism=Drosophila melanogaster, GI24645930, Length=580, Percent_Identity=30.3448275862069, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24642057, Length=593, Percent_Identity=29.6795952782462, Blast_Score=161, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011533
- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.1 [H]

Molecular weight: Translated: 58989; Mature: 58858

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHAESYDYIIVGAGSAGCVLANRLSADPRCSVLLLEAGGWDRDPMIHIPLGWGKILTER
CCCCCCCCEEEEECCCCCEEEEHHCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHC
RHDWMYFCEPEDNVGGRRVECARGKVIGGSSSTNAMAYVRGNRGDYDRWAATGLSEWSYD
CCCEEEEECCCCCCCCCEEEECCCEEECCCCCCCEEEEEECCCCCCHHHHHCCCCCCCHH
KVLPYFRKQESWEGGANQYRGGNGPVSTQFCRYKDTLIDAFAQASVQAGYAQTKDYNGER
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
QEGFGRLQMTISKGRRASTASAYLRPVLKRPNLTVLTEASATRIVLEGARATGVTINHRG
HCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCEEEECCC
GERTVLARKEVLLAGGVINTPQLMMLSGIGAQDELAAHGVQTRVNLPAVGKNLQDHVSVI
CCEEEEEHHEEEEECCCCCCCCEEEEECCCCHHHHHHCCCCEEECCCHHCCCHHHHHHHH
LMYRRRAPGGPFLRNMRADRIGFDFVKTYLTGRGFSGDVPGGVVAFLKSGPARPLPDVQL
HHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEE
LFTAAPLAAWPYFKPFKAPFADGFATRIVATQPESRGAVKLASADPSAAPLIHQNFLASP
EEECCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHCCCC
KDWESLRAGFRVARDLAAQPSMQPFIEAEFFPGPKCQSDDEIDEHIRKTSITVHHPAGTC
CCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCCC
RMGADAASVVDPQLRVRGVDRLRVVDASVMPDLVCGNINAAVIMIAEKAADLIASSKEGR
CCCCCHHHHCCCHHEECCCCEEEEECHHHCCHHEECCCCEEEEEEEHHHHHHHHCCCCCC
AVQ
CCC
>Mature Secondary Structure 
PHAESYDYIIVGAGSAGCVLANRLSADPRCSVLLLEAGGWDRDPMIHIPLGWGKILTER
CCCCCCCEEEEECCCCCEEEEHHCCCCCCEEEEEEECCCCCCCCEEEEECCHHHHHHHC
RHDWMYFCEPEDNVGGRRVECARGKVIGGSSSTNAMAYVRGNRGDYDRWAATGLSEWSYD
CCCEEEEECCCCCCCCCEEEECCCEEECCCCCCCEEEEEECCCCCCHHHHHCCCCCCCHH
KVLPYFRKQESWEGGANQYRGGNGPVSTQFCRYKDTLIDAFAQASVQAGYAQTKDYNGER
HHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
QEGFGRLQMTISKGRRASTASAYLRPVLKRPNLTVLTEASATRIVLEGARATGVTINHRG
HCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCEEEEEECCCCCCEEEECCC
GERTVLARKEVLLAGGVINTPQLMMLSGIGAQDELAAHGVQTRVNLPAVGKNLQDHVSVI
CCEEEEEHHEEEEECCCCCCCCEEEEECCCCHHHHHHCCCCEEECCCHHCCCHHHHHHHH
LMYRRRAPGGPFLRNMRADRIGFDFVKTYLTGRGFSGDVPGGVVAFLKSGPARPLPDVQL
HHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCEE
LFTAAPLAAWPYFKPFKAPFADGFATRIVATQPESRGAVKLASADPSAAPLIHQNFLASP
EEECCCHHHCCCCCCCCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCHHHHHHCCCC
KDWESLRAGFRVARDLAAQPSMQPFIEAEFFPGPKCQSDDEIDEHIRKTSITVHHPAGTC
CCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHEEEEECCCCCC
RMGADAASVVDPQLRVRGVDRLRVVDASVMPDLVCGNINAAVIMIAEKAADLIASSKEGR
CCCCCHHHHCCCHHEECCCCEEEEECHHHCCHHEECCCCEEEEEEEHHHHHHHHCCCCCC
AVQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA