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The map label for this gene is arcB [H]

Identifier: 13475656

GI number: 13475656

Start: 5579796

End: 5580728

Strand: Reverse

Name: arcB [H]

Synonym: mll6778

Alternate gene names: 13475656

Gene position: 5580728-5579796 (Counterclockwise)

Preceding gene: 13475658

Following gene: 13475655

Centisome position: 79.32

GC content: 66.56

Gene sequence:

>933_bases
ATGCGTTGCAAAATCGTCGGGGCACCGGTGCAGGACGGCGCCGGCAGAATGGGCTGCGAAATGGGGCCGAGTGCGCTGAG
GACGGCAGGGCTTGCCGAAGTGCTGTCCGGCCTCGGCCACACTGTCGAGGATATGGGCGCCGTCCAGCCAATGCCGGCGA
GGCGCGTCGTGCACGGCAATCTGGCGCTGAAGGCCTTGCCCGAAATATCGGCCTGGACATCCGCCATCGCAGCGGCAGCT
TACGCAGCGAGCGAGGATGCCATGCCGATTTTCCTTGGCGGTGACCATTCGATCTCGGCGGGAACCGTGTCGGGCCTCGC
CCGCCGCGCCGCCGAGGCCGGGCGCCCGCTGTTCGTGCTGTGGCTCGATGCGCATCCGGACTTCCACACGCTGGACACCA
CCGCCAGCGGCAATCTGCACGGTGTTCCGCTCGCCTATGCCAGCGGCCAGCCGGGTTTCAGCGGCTATTTTCCCGATCTG
CCGGCGGCGGTCGACCCCAAGCGTATCTGCACAATGGGCCTGCGCAGTGTCGACCCGGCCGAGCGCAGCGCGCTCAACCA
GGCGGGCGTAACCGTGCACGACATGCGCGCCATTGATGAACATGGTATCGCGCCGCTGCTGCGCGCCTTCCTGGCGCGCG
TGTCTGATGAAGACGGACTGCTGCATGTCAGTCTCGACGTCGACTTTCTCGACCCGTCGATTGCGCCGGCTGTCGGCACC
ACGGTTCCCGGCGGCGCGACGTTCCGCGAAGCGCATCTGGTGATGGAGATGCTGTCCGACAGCGGACTCGTCTCCAGTCT
CGACCTGGTCGAGTTGAATCCATTTCTGGACGAGCGTGGCCGGACCGCGACGCTCATGGTCGACCTGACGGCGAGCCTGA
TGGGCCGCCGCATCATGGATCGCCCGACCCGCAGCCATTCCGGGAGCTTTTGA

Upstream 100 bases:

>100_bases
TGATAGATGATGCTTCGCGGATTGCCAATTCTGTCTGTTCATACTGCCGGCTCGCCATGATCTCCTCTCCCCCATTCGAA
CTTTGGCCGCGGGAAAGACA

Downstream 100 bases:

>100_bases
TCATGACCACGGCAAAGCTGAACATCGTCCCCTTCGTCAGCGTCGACCGCATGATGAAGCTGGTGCTTGCCATCGGCGTC
GAACGCTTTCTGACCGAGCT

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MRCKIVGAPVQDGAGRMGCEMGPSALRTAGLAEVLSGLGHTVEDMGAVQPMPARRVVHGNLALKALPEISAWTSAIAAAA
YAASEDAMPIFLGGDHSISAGTVSGLARRAAEAGRPLFVLWLDAHPDFHTLDTTASGNLHGVPLAYASGQPGFSGYFPDL
PAAVDPKRICTMGLRSVDPAERSALNQAGVTVHDMRAIDEHGIAPLLRAFLARVSDEDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLVMEMLSDSGLVSSLDLVELNPFLDERGRTATLMVDLTASLMGRRIMDRPTRSHSGSF

Sequences:

>Translated_310_residues
MRCKIVGAPVQDGAGRMGCEMGPSALRTAGLAEVLSGLGHTVEDMGAVQPMPARRVVHGNLALKALPEISAWTSAIAAAA
YAASEDAMPIFLGGDHSISAGTVSGLARRAAEAGRPLFVLWLDAHPDFHTLDTTASGNLHGVPLAYASGQPGFSGYFPDL
PAAVDPKRICTMGLRSVDPAERSALNQAGVTVHDMRAIDEHGIAPLLRAFLARVSDEDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLVMEMLSDSGLVSSLDLVELNPFLDERGRTATLMVDLTASLMGRRIMDRPTRSHSGSF
>Mature_310_residues
MRCKIVGAPVQDGAGRMGCEMGPSALRTAGLAEVLSGLGHTVEDMGAVQPMPARRVVHGNLALKALPEISAWTSAIAAAA
YAASEDAMPIFLGGDHSISAGTVSGLARRAAEAGRPLFVLWLDAHPDFHTLDTTASGNLHGVPLAYASGQPGFSGYFPDL
PAAVDPKRICTMGLRSVDPAERSALNQAGVTVHDMRAIDEHGIAPLLRAFLARVSDEDGLLHVSLDVDFLDPSIAPAVGT
TVPGGATFREAHLVMEMLSDSGLVSSLDLVELNPFLDERGRTATLMVDLTASLMGRRIMDRPTRSHSGSF

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=307, Percent_Identity=38.1107491856677, Blast_Score=180, Evalue=1e-45,
Organism=Homo sapiens, GI10947139, Length=308, Percent_Identity=35.0649350649351, Blast_Score=159, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71996843, Length=203, Percent_Identity=31.5270935960591, Blast_Score=93, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325146, Length=294, Percent_Identity=33.3333333333333, Blast_Score=147, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24638886, Length=318, Percent_Identity=30.188679245283, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32495; Mature: 32495

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCKIVGAPVQDGAGRMGCEMGPSALRTAGLAEVLSGLGHTVEDMGAVQPMPARRVVHGN
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECC
LALKALPEISAWTSAIAAAAYAASEDAMPIFLGGDHSISAGTVSGLARRAAEAGRPLFVL
CCEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEE
WLDAHPDFHTLDTTASGNLHGVPLAYASGQPGFSGYFPDLPAAVDPKRICTMGLRSVDPA
EEECCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHH
ERSALNQAGVTVHDMRAIDEHGIAPLLRAFLARVSDEDGLLHVSLDVDFLDPSIAPAVGT
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCC
TVPGGATFREAHLVMEMLSDSGLVSSLDLVELNPFLDERGRTATLMVDLTASLMGRRIMD
CCCCCCHHHHHHHHHHHHHCCCCEEECCEEECCHHHHCCCCEEEEEEEEHHHHHHHHHHC
RPTRSHSGSF
CCCCCCCCCC
>Mature Secondary Structure
MRCKIVGAPVQDGAGRMGCEMGPSALRTAGLAEVLSGLGHTVEDMGAVQPMPARRVVHGN
CCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEECC
LALKALPEISAWTSAIAAAAYAASEDAMPIFLGGDHSISAGTVSGLARRAAEAGRPLFVL
CCEECCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEE
WLDAHPDFHTLDTTASGNLHGVPLAYASGQPGFSGYFPDLPAAVDPKRICTMGLRSVDPA
EEECCCCCEEECCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCHH
ERSALNQAGVTVHDMRAIDEHGIAPLLRAFLARVSDEDGLLHVSLDVDFLDPSIAPAVGT
HHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCCC
TVPGGATFREAHLVMEMLSDSGLVSSLDLVELNPFLDERGRTATLMVDLTASLMGRRIMD
CCCCCCHHHHHHHHHHHHHCCCCEEECCEEECCHHHHCCCCEEEEEEEEHHHHHHHHHHC
RPTRSHSGSF
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9375792 [H]