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The map label for this gene is arcB [H]

Identifier: 13475583

GI number: 13475583

Start: 5485311

End: 5487227

Strand: Direct

Name: arcB [H]

Synonym: mlr6689

Alternate gene names: 13475583

Gene position: 5485311-5487227 (Clockwise)

Preceding gene: 13475578

Following gene: 13475584

Centisome position: 77.96

GC content: 62.34

Gene sequence:

>1917_bases
ATGGTGATCGGCATCCTGCTCGACCGGCAACAGCGGCGGCGCGATCTCTCCAGGTCCAACATGATCTATCGGGCCATGGT
TCGCGAGCTGCCGGACTGCCTGAACATAAAGGATGTGGACGGCCGCTTCATCGCCGCCAATCCCGCCACCGCCGAAATGC
TGGGGGCCGCTTCAGTCGAGGAGCTCATCGGCAAGACCGATTTCGATTTCTATTCGAAGGACGTGGCCGAGCGCTTCAGG
CAGGACGAGATGGGCGCACTGAAGGCCGGGCAGACATTGCGCATCGAACAGCCGGCGGTGTTTCCGGATGGCAAACAGGG
CTGGCTTTACACGCTCAAGGCGCCGTTCCGCGATGAGGCCGGCAAGATCACCGGTGTCATCACCTACAATCGCGAGATCA
CCGAGCAGAAGCGAAACGCTCAGCTCAAGAACGATTTCATTTCGACGGTCAGTCATGAGCTGCGCACCCCTCTGACATCC
ATCCGCGGCTCGCTGGGCCTGATCGCGGCGGGCGTGGTGGGCGAATTGCCGCCGAAGGCCGCCAACCTCGTCAACATCGC
TCACACCAACAGCGAGAGACTGGTTCTTCTCATCAACGACATCCTCGACATGGAGAAGATCGAGTCAGGTGTGATCGCCT
TCAAGATCAAGCAGATGCCTGTGCGCCCGATTATGGAGCAGGCCATTGCCGCCAGTTCCAACTACATGGCCGAGAGCCGG
ATACGCATCGTCCTGGTCGACGATGCCCCGCGCGCCGAAGCCAACATCGATCCGGACCGCCTGCACCAGGTGATGGCCAA
CCTTCTGTCGAACGCGATCAAGTTCTCGCACGCCGACGGCACCGTGATGGTGAAGCTACAGCGTCGTGATCGCGACATGT
TGCGCATCTCGGTGATCGATCAGGGGGCCGGTATCCCCGAGGCGTTTCGCAGCCGTATATTCGGCAAGTTCGAACAGGCC
GACGCGTCCAGCACCCGCAAGAAAGGCGGCACCGGCCTCGGCCTCAGCATCGTCAAGACCATCGTGGAAAAGCTGGGCGG
CGCCGTTTCCTTCGAAACCGAGGAAGAGAAAGGAACCTCGTTCCACGTCGACCTTGCCGAAGCCCGCAGGCTCCACCCGA
GGCCGTATCCGCCACCGCGCCCGCCGCGTGAGCCCGATGGCCGCCTACGGGTTCTGATCTGCGAAGACGAGACCGACGTC
GCCACGGTAATTGCGGCACTCCTGGACTCGGAAGGCTTTTCCAGCGACGTGGCCCCGGACATCGCCACCGCGAAGGCGCT
TCTGCAGTCCCGCGATTACGCGGCACTGACACTCGACATCAAGCTGGCAGAAGAATCGGGTATCAAGCTCTTCCATGACA
TCAGGGCGTCACCAGTGAATTCCGACATTGCGGTCATCGTCATCTCCGCCGTCGCCGATGAGGCCAGGCGCTCGCTGAAC
GGCACCGCCGTCGGCATCGTCGACTGGCTGGAGAAGCCGGTGGATTCGGGGCGGCTTCACGCCGCTCTTGCCAAGATCGT
CGCCAGCAGGAATGAGCAGAGGCCGAAGATCCTCCATGTCGAGGACGACGAGGGTGTGCTAGCCGTGATGTCGGCGGGGC
TGGGCTCCGACGTCTCGATCATCTCGGCGAAAACGCTGCAGGAGGCACGGCGGGCGGTTGCGAAGCGTCACTTCGACCTG
GTCATCCTCGACATAGCGCTTCCAGACGGATCGGGACTGGACCTGCTCGCCGATCTGCCGCTGGAGACCGGAGTCATCGT
GTTCTCGGCGGCGGAACCGGACCAGAAACTCGGCGATCGGGTGCAGGCGATGATGACCAAGACCAGGGCGTCGGAGATCG
ATGTCGCAAAGCTGGTCAGAACCATGTTGGCCTCATCGCGAGATGGCACCAGACCCGCCGGCCGCGCCAAGGAGTGA

Upstream 100 bases:

>100_bases
CGCCGGGTTGATCACGCTGCTGGTCATACCCCAGCAAGTCATCACAGGCCTGATCCAGCAGAGCACGTTCCCGTCCCTCC
TGTTCCGCTTCCTCAGCACC

Downstream 100 bases:

>100_bases
CGATCATGCCGGCAAGGATCCTCTACGTGGATGACGAGGACGATATCCGCGAAATCGCTCAGATGTCGCTGGAGCTCGAT
CCGGAATTCGAGGTGCGGTC

Product: two-component sensor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 638

Protein sequence:

>638_residues
MVIGILLDRQQRRRDLSRSNMIYRAMVRELPDCLNIKDVDGRFIAANPATAEMLGAASVEELIGKTDFDFYSKDVAERFR
QDEMGALKAGQTLRIEQPAVFPDGKQGWLYTLKAPFRDEAGKITGVITYNREITEQKRNAQLKNDFISTVSHELRTPLTS
IRGSLGLIAAGVVGELPPKAANLVNIAHTNSERLVLLINDILDMEKIESGVIAFKIKQMPVRPIMEQAIAASSNYMAESR
IRIVLVDDAPRAEANIDPDRLHQVMANLLSNAIKFSHADGTVMVKLQRRDRDMLRISVIDQGAGIPEAFRSRIFGKFEQA
DASSTRKKGGTGLGLSIVKTIVEKLGGAVSFETEEEKGTSFHVDLAEARRLHPRPYPPPRPPREPDGRLRVLICEDETDV
ATVIAALLDSEGFSSDVAPDIATAKALLQSRDYAALTLDIKLAEESGIKLFHDIRASPVNSDIAVIVISAVADEARRSLN
GTAVGIVDWLEKPVDSGRLHAALAKIVASRNEQRPKILHVEDDEGVLAVMSAGLGSDVSIISAKTLQEARRAVAKRHFDL
VILDIALPDGSGLDLLADLPLETGVIVFSAAEPDQKLGDRVQAMMTKTRASEIDVAKLVRTMLASSRDGTRPAGRAKE

Sequences:

>Translated_638_residues
MVIGILLDRQQRRRDLSRSNMIYRAMVRELPDCLNIKDVDGRFIAANPATAEMLGAASVEELIGKTDFDFYSKDVAERFR
QDEMGALKAGQTLRIEQPAVFPDGKQGWLYTLKAPFRDEAGKITGVITYNREITEQKRNAQLKNDFISTVSHELRTPLTS
IRGSLGLIAAGVVGELPPKAANLVNIAHTNSERLVLLINDILDMEKIESGVIAFKIKQMPVRPIMEQAIAASSNYMAESR
IRIVLVDDAPRAEANIDPDRLHQVMANLLSNAIKFSHADGTVMVKLQRRDRDMLRISVIDQGAGIPEAFRSRIFGKFEQA
DASSTRKKGGTGLGLSIVKTIVEKLGGAVSFETEEEKGTSFHVDLAEARRLHPRPYPPPRPPREPDGRLRVLICEDETDV
ATVIAALLDSEGFSSDVAPDIATAKALLQSRDYAALTLDIKLAEESGIKLFHDIRASPVNSDIAVIVISAVADEARRSLN
GTAVGIVDWLEKPVDSGRLHAALAKIVASRNEQRPKILHVEDDEGVLAVMSAGLGSDVSIISAKTLQEARRAVAKRHFDL
VILDIALPDGSGLDLLADLPLETGVIVFSAAEPDQKLGDRVQAMMTKTRASEIDVAKLVRTMLASSRDGTRPAGRAKE
>Mature_638_residues
MVIGILLDRQQRRRDLSRSNMIYRAMVRELPDCLNIKDVDGRFIAANPATAEMLGAASVEELIGKTDFDFYSKDVAERFR
QDEMGALKAGQTLRIEQPAVFPDGKQGWLYTLKAPFRDEAGKITGVITYNREITEQKRNAQLKNDFISTVSHELRTPLTS
IRGSLGLIAAGVVGELPPKAANLVNIAHTNSERLVLLINDILDMEKIESGVIAFKIKQMPVRPIMEQAIAASSNYMAESR
IRIVLVDDAPRAEANIDPDRLHQVMANLLSNAIKFSHADGTVMVKLQRRDRDMLRISVIDQGAGIPEAFRSRIFGKFEQA
DASSTRKKGGTGLGLSIVKTIVEKLGGAVSFETEEEKGTSFHVDLAEARRLHPRPYPPPRPPREPDGRLRVLICEDETDV
ATVIAALLDSEGFSSDVAPDIATAKALLQSRDYAALTLDIKLAEESGIKLFHDIRASPVNSDIAVIVISAVADEARRSLN
GTAVGIVDWLEKPVDSGRLHAALAKIVASRNEQRPKILHVEDDEGVLAVMSAGLGSDVSIISAKTLQEARRAVAKRHFDL
VILDIALPDGSGLDLLADLPLETGVIVFSAAEPDQKLGDRVQAMMTKTRASEIDVAKLVRTMLASSRDGTRPAGRAKE

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=530, Percent_Identity=26.4150943396226, Blast_Score=168, Evalue=1e-42,
Organism=Escherichia coli, GI1789149, Length=492, Percent_Identity=27.2357723577236, Blast_Score=149, Evalue=7e-37,
Organism=Escherichia coli, GI145693157, Length=229, Percent_Identity=38.4279475982533, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788713, Length=547, Percent_Identity=24.6800731261426, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI87081816, Length=332, Percent_Identity=32.5301204819277, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788393, Length=256, Percent_Identity=28.90625, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082128, Length=231, Percent_Identity=29.4372294372294, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1786600, Length=372, Percent_Identity=25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=29.7071129707113, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=230, Percent_Identity=28.2608695652174, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=28.3898305084746, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1790861, Length=218, Percent_Identity=27.0642201834862, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=24.8995983935743, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788549, Length=344, Percent_Identity=22.093023255814, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI1787894, Length=220, Percent_Identity=27.7272727272727, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790300, Length=338, Percent_Identity=24.2603550295858, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 69700; Mature: 69700

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIGILLDRQQRRRDLSRSNMIYRAMVRELPDCLNIKDVDGRFIAANPATAEMLGAASVE
CEEEEEECCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEEECCCCHHHHHHHHHHH
ELIGKTDFDFYSKDVAERFRQDEMGALKAGQTLRIEQPAVFPDGKQGWLYTLKAPFRDEA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCC
GKITGVITYNREITEQKRNAQLKNDFISTVSHELRTPLTSIRGSLGLIAAGVVGELPPKA
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCH
ANLVNIAHTNSERLVLLINDILDMEKIESGVIAFKIKQMPVRPIMEQAIAASSNYMAESR
HCEEEEEECCCCEEEEEHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCEECCC
IRIVLVDDAPRAEANIDPDRLHQVMANLLSNAIKFSHADGTVMVKLQRRDRDMLRISVID
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCEEEEEEEE
QGAGIPEAFRSRIFGKFEQADASSTRKKGGTGLGLSIVKTIVEKLGGAVSFETEEEKGTS
CCCCCHHHHHHHHCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCE
FHVDLAEARRLHPRPYPPPRPPREPDGRLRVLICEDETDVATVIAALLDSEGFSSDVAPD
EEEEHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCH
IATAKALLQSRDYAALTLDIKLAEESGIKLFHDIRASPVNSDIAVIVISAVADEARRSLN
HHHHHHHHHCCCCEEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEEEHHHHHHHHHHCC
GTAVGIVDWLEKPVDSGRLHAALAKIVASRNEQRPKILHVEDDEGVLAVMSAGLGSDVSI
CCEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCHH
ISAKTLQEARRAVAKRHFDLVILDIALPDGSGLDLLADLPLETGVIVFSAAEPDQKLGDR
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCEEEEECCCCHHHHHHH
VQAMMTKTRASEIDVAKLVRTMLASSRDGTRPAGRAKE
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MVIGILLDRQQRRRDLSRSNMIYRAMVRELPDCLNIKDVDGRFIAANPATAEMLGAASVE
CEEEEEECCHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCEEEECCCCHHHHHHHHHHH
ELIGKTDFDFYSKDVAERFRQDEMGALKAGQTLRIEQPAVFPDGKQGWLYTLKAPFRDEA
HHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEEEECCCCCCC
GKITGVITYNREITEQKRNAQLKNDFISTVSHELRTPLTSIRGSLGLIAAGVVGELPPKA
CCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHCCCCCCH
ANLVNIAHTNSERLVLLINDILDMEKIESGVIAFKIKQMPVRPIMEQAIAASSNYMAESR
HCEEEEEECCCCEEEEEHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHHCCCCEECCC
IRIVLVDDAPRAEANIDPDRLHQVMANLLSNAIKFSHADGTVMVKLQRRDRDMLRISVID
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCEEEEEEECCCCCEEEEEEEE
QGAGIPEAFRSRIFGKFEQADASSTRKKGGTGLGLSIVKTIVEKLGGAVSFETEEEKGTS
CCCCCHHHHHHHHCCCHHHCCCHHHHHCCCCCCCHHHHHHHHHHHCCEEEECCCCCCCCE
FHVDLAEARRLHPRPYPPPRPPREPDGRLRVLICEDETDVATVIAALLDSEGFSSDVAPD
EEEEHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCH
IATAKALLQSRDYAALTLDIKLAEESGIKLFHDIRASPVNSDIAVIVISAVADEARRSLN
HHHHHHHHHCCCCEEEEEEEEECCCCCCEEEECCCCCCCCCCEEEEEEHHHHHHHHHHCC
GTAVGIVDWLEKPVDSGRLHAALAKIVASRNEQRPKILHVEDDEGVLAVMSAGLGSDVSI
CCEEHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEECCCCCCCHH
ISAKTLQEARRAVAKRHFDLVILDIALPDGSGLDLLADLPLETGVIVFSAAEPDQKLGDR
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCEEEEECCCCHHHHHHH
VQAMMTKTRASEIDVAKLVRTMLASSRDGTRPAGRAKE
HHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]