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The map label for this gene is betA [C]

Identifier: 13475556

GI number: 13475556

Start: 5453882

End: 5455528

Strand: Direct

Name: betA [C]

Synonym: mlr6656

Alternate gene names: 13475556

Gene position: 5453882-5455528 (Clockwise)

Preceding gene: 13475555

Following gene: 13475557

Centisome position: 77.51

GC content: 59.32

Gene sequence:

>1647_bases
ATGGCTAATTTTGGATCCGCTCGATGGGGAATTCTGCCGCGATCCGAGACAGTCGCAGGGAAGTGCGACTACATCGTCGT
CGGTGGCGGCTCAACCGGTTGTGTCGTTGCTTCCCGACTGTCCGAAAATGCTGATGTCTCGGTCGTCCTGCTCGAAGAGG
GGCCGAATGATATCAACCCGTACATACATATACCGGGGGCGTATTACAAAACTGCCCAAGGGCCTTTGCTGAAGCGAATC
CCCTGGGAGCCGATGGCCGGGCAATCGCCCGATGCAACGCCTACAATGGTCCAGGCGAGCGTCTTGGGTGGCGGGAGCTC
TGTCAATGCCATGATCTATATCCGCGGCGTTCCTTCAGACTATGCGCGTTGGGAAGAACTTGGCGCCAGCGGCTGGAACT
ATGGCGATGTGCTGCCGTATTTTCTTCGCTCGGAGGACAACAACAGGTTCTGCAACGAAGCGCATGCGGTTGGCGGCCCG
CTGGGGGTCTCCGACATTGACAACATTCATCCGCTAACACGCGCTTGGCTCCAGGCATGCCAGCAGGCGGGTCTCCCTTA
TAACCACGATTTCAATTCTGGCGATCAGGCCGGATCTGGCCTTTACCAGATCACGGCCAGAAACGGTCTGCGCAGCAGTG
CCGCTACTGCTTTCCTGAAGCCTGTTCGCCGTCGTCCGAACCTGCAGGTTCGGACACGCGCGCGCGTCAGCCGGATCATC
GTCGAACAAGGCAGGGCGACCGGCGTCGAATATTTCGTGAACGGTCGCAGGTGGGTTCTCCACGCAGAGCGCGAGGTCAT
CTTGTCGGCAGGCGCAATCTCTTCGCCGAAACTGTTGATGTTGTCGGGCATCGGCCCGGCGGACGCACTGCGCAGACATG
GGATCCAGGTGGAGATGGATCTACCAGGCGTAGGCCAGAATCTGCAGGACCATATTGAGATGTCGCTGGTCTACCAGCTC
AACGGACCGCACAGCTACGACAAATACAAGAAGCTGCATTGGAAGGCCGCGGCAGCACTGAACTACCTTCTGTTTCGTGG
CGGGCCGGCTTCATCGAATCTGATAGAAGGCGGCGCCTTCTGGTGGGGAAACAAGAATGAAACCGTGCCCGACGTCCAGT
TCTTCATGGTGGTAGGTGCCGGTATCGAGGAAGGCGTCGATACTGTTCCGGGCGGCAATGGCTGCACCGTCAACCTTGGT
CAGATAAGACCGCGCTCTCGCGGCGAAGTCACGCTCCAGAGTGCGAACCCTGCCGAAAATCCGCGAGTCGCGCCCCGATA
TTTCTCCGATCCTTACGATCTTGACGCGGTGACCGAAGGCACCATGGCTGCGCTCGACATCATGGAGAAGCCGGCGATCA
GCCGCTATATCGCGGCGCGGCAAACGCCTGCGCCCACTATGAAGACCCGCTCGGACATCAGAAATTTCTGCCTTGAAACG
GCCCATGCTGCGCTACACCCAGCCGGCACCTGCCGGATGGGCCAGGACGAAATGGCGGTTGTCGGCCCGGATCTTCGTGT
CCGCGGGATTGACGGACTACGCGTGGCGGATGCCTCGGTCATGCCGACGCTAATCTCGGGAAATCCCAACGCCGTCTGCA
TCATGATAGGCGAGAGAGCGGCATCGTTTCTGTCAGAGGCGGCTTGA

Upstream 100 bases:

>100_bases
AGACGCATCTGTGCTGCCGACGTCGGCGGCAGTAAATCCTGCGTTGACCATAGCGGCTCTGGCTCTGAAAGCCGGAGCGG
CGATCAGGGCGATGTGAACC

Downstream 100 bases:

>100_bases
CTATCCTTGTCATTGCTTGCCGGGAGGCAAAAGGATTGACACTGCGAACTATCCGACATGGCACGGTGCCATTCGATACC
GAAGTCGCGACCGCGGAGAT

Product: dehydrogenase

Products: NA

Alternate protein names: SDH [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MANFGSARWGILPRSETVAGKCDYIVVGGGSTGCVVASRLSENADVSVVLLEEGPNDINPYIHIPGAYYKTAQGPLLKRI
PWEPMAGQSPDATPTMVQASVLGGGSSVNAMIYIRGVPSDYARWEELGASGWNYGDVLPYFLRSEDNNRFCNEAHAVGGP
LGVSDIDNIHPLTRAWLQACQQAGLPYNHDFNSGDQAGSGLYQITARNGLRSSAATAFLKPVRRRPNLQVRTRARVSRII
VEQGRATGVEYFVNGRRWVLHAEREVILSAGAISSPKLLMLSGIGPADALRRHGIQVEMDLPGVGQNLQDHIEMSLVYQL
NGPHSYDKYKKLHWKAAAALNYLLFRGGPASSNLIEGGAFWWGNKNETVPDVQFFMVVGAGIEEGVDTVPGGNGCTVNLG
QIRPRSRGEVTLQSANPAENPRVAPRYFSDPYDLDAVTEGTMAALDIMEKPAISRYIAARQTPAPTMKTRSDIRNFCLET
AHAALHPAGTCRMGQDEMAVVGPDLRVRGIDGLRVADASVMPTLISGNPNAVCIMIGERAASFLSEAA

Sequences:

>Translated_548_residues
MANFGSARWGILPRSETVAGKCDYIVVGGGSTGCVVASRLSENADVSVVLLEEGPNDINPYIHIPGAYYKTAQGPLLKRI
PWEPMAGQSPDATPTMVQASVLGGGSSVNAMIYIRGVPSDYARWEELGASGWNYGDVLPYFLRSEDNNRFCNEAHAVGGP
LGVSDIDNIHPLTRAWLQACQQAGLPYNHDFNSGDQAGSGLYQITARNGLRSSAATAFLKPVRRRPNLQVRTRARVSRII
VEQGRATGVEYFVNGRRWVLHAEREVILSAGAISSPKLLMLSGIGPADALRRHGIQVEMDLPGVGQNLQDHIEMSLVYQL
NGPHSYDKYKKLHWKAAAALNYLLFRGGPASSNLIEGGAFWWGNKNETVPDVQFFMVVGAGIEEGVDTVPGGNGCTVNLG
QIRPRSRGEVTLQSANPAENPRVAPRYFSDPYDLDAVTEGTMAALDIMEKPAISRYIAARQTPAPTMKTRSDIRNFCLET
AHAALHPAGTCRMGQDEMAVVGPDLRVRGIDGLRVADASVMPTLISGNPNAVCIMIGERAASFLSEAA
>Mature_547_residues
ANFGSARWGILPRSETVAGKCDYIVVGGGSTGCVVASRLSENADVSVVLLEEGPNDINPYIHIPGAYYKTAQGPLLKRIP
WEPMAGQSPDATPTMVQASVLGGGSSVNAMIYIRGVPSDYARWEELGASGWNYGDVLPYFLRSEDNNRFCNEAHAVGGPL
GVSDIDNIHPLTRAWLQACQQAGLPYNHDFNSGDQAGSGLYQITARNGLRSSAATAFLKPVRRRPNLQVRTRARVSRIIV
EQGRATGVEYFVNGRRWVLHAEREVILSAGAISSPKLLMLSGIGPADALRRHGIQVEMDLPGVGQNLQDHIEMSLVYQLN
GPHSYDKYKKLHWKAAAALNYLLFRGGPASSNLIEGGAFWWGNKNETVPDVQFFMVVGAGIEEGVDTVPGGNGCTVNLGQ
IRPRSRGEVTLQSANPAENPRVAPRYFSDPYDLDAVTEGTMAALDIMEKPAISRYIAARQTPAPTMKTRSDIRNFCLETA
HAALHPAGTCRMGQDEMAVVGPDLRVRGIDGLRVADASVMPTLISGNPNAVCIMIGERAASFLSEAA

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI217272839, Length=545, Percent_Identity=38.1651376146789, Blast_Score=339, Evalue=4e-93,
Organism=Escherichia coli, GI1786503, Length=537, Percent_Identity=35.7541899441341, Blast_Score=298, Evalue=7e-82,
Organism=Caenorhabditis elegans, GI17532301, Length=569, Percent_Identity=35.1493848857645, Blast_Score=322, Evalue=4e-88,
Organism=Drosophila melanogaster, GI24642042, Length=572, Percent_Identity=38.2867132867133, Blast_Score=315, Evalue=6e-86,
Organism=Drosophila melanogaster, GI45551458, Length=568, Percent_Identity=36.9718309859155, Blast_Score=313, Evalue=3e-85,
Organism=Drosophila melanogaster, GI45549471, Length=568, Percent_Identity=36.9718309859155, Blast_Score=312, Evalue=3e-85,
Organism=Drosophila melanogaster, GI24642048, Length=574, Percent_Identity=36.411149825784, Blast_Score=308, Evalue=7e-84,
Organism=Drosophila melanogaster, GI24642055, Length=593, Percent_Identity=35.2445193929174, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24642059, Length=569, Percent_Identity=34.4463971880492, Blast_Score=280, Evalue=1e-75,
Organism=Drosophila melanogaster, GI24642039, Length=572, Percent_Identity=34.6153846153846, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI17137792, Length=553, Percent_Identity=34.5388788426763, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24650267, Length=596, Percent_Identity=34.0604026845638, Blast_Score=265, Evalue=7e-71,
Organism=Drosophila melanogaster, GI24642037, Length=571, Percent_Identity=35.0262697022767, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI18859995, Length=575, Percent_Identity=33.7391304347826, Blast_Score=261, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24642035, Length=570, Percent_Identity=33.6842105263158, Blast_Score=252, Evalue=5e-67,
Organism=Drosophila melanogaster, GI18859993, Length=582, Percent_Identity=31.2714776632302, Blast_Score=236, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24642051, Length=571, Percent_Identity=30.6479859894921, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI24642057, Length=587, Percent_Identity=29.9829642248722, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24645930, Length=586, Percent_Identity=27.3037542662116, Blast_Score=137, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012132
- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: =1.1.99.32 [H]

Molecular weight: Translated: 59099; Mature: 58968

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00624 GMC_OXRED_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANFGSARWGILPRSETVAGKCDYIVVGGGSTGCVVASRLSENADVSVVLLEEGPNDINP
CCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHEEECCCCCCCEEEEEEECCCCCCCC
YIHIPGAYYKTAQGPLLKRIPWEPMAGQSPDATPTMVQASVLGGGSSVNAMIYIRGVPSD
EEECCCCCEECCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCH
YARWEELGASGWNYGDVLPYFLRSEDNNRFCNEAHAVGGPLGVSDIDNIHPLTRAWLQAC
HHHHHHHCCCCCCCCCCCHHHEECCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
QQAGLPYNHDFNSGDQAGSGLYQITARNGLRSSAATAFLKPVRRRPNLQVRTRARVSRII
HHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
VEQGRATGVEYFVNGRRWVLHAEREVILSAGAISSPKLLMLSGIGPADALRRHGIQVEMD
HHCCCCCCEEEEECCCEEEEEECCEEEEECCCCCCCCEEEEECCCHHHHHHHCCCEEEEE
LPGVGQNLQDHIEMSLVYQLNGPHSYDKYKKLHWKAAAALNYLLFRGGPASSNLIEGGAF
CCCCCCCHHHCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCEECCCEE
WWGNKNETVPDVQFFMVVGAGIEEGVDTVPGGNGCTVNLGQIRPRSRGEVTLQSANPAEN
EECCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCC
PRVAPRYFSDPYDLDAVTEGTMAALDIMEKPAISRYIAARQTPAPTMKTRSDIRNFCLET
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AHAALHPAGTCRMGQDEMAVVGPDLRVRGIDGLRVADASVMPTLISGNPNAVCIMIGERA
HHHHCCCCCCCCCCCCCEEEECCCEEEECCCCCEEECCCCCCEEECCCCCEEEEEECCHH
ASFLSEAA
HHHHHHCC
>Mature Secondary Structure 
ANFGSARWGILPRSETVAGKCDYIVVGGGSTGCVVASRLSENADVSVVLLEEGPNDINP
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHEEECCCCCCCEEEEEEECCCCCCCC
YIHIPGAYYKTAQGPLLKRIPWEPMAGQSPDATPTMVQASVLGGGSSVNAMIYIRGVPSD
EEECCCCCEECCCCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEEEEECCCH
YARWEELGASGWNYGDVLPYFLRSEDNNRFCNEAHAVGGPLGVSDIDNIHPLTRAWLQAC
HHHHHHHCCCCCCCCCCCHHHEECCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
QQAGLPYNHDFNSGDQAGSGLYQITARNGLRSSAATAFLKPVRRRPNLQVRTRARVSRII
HHCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHH
VEQGRATGVEYFVNGRRWVLHAEREVILSAGAISSPKLLMLSGIGPADALRRHGIQVEMD
HHCCCCCCEEEEECCCEEEEEECCEEEEECCCCCCCCEEEEECCCHHHHHHHCCCEEEEE
LPGVGQNLQDHIEMSLVYQLNGPHSYDKYKKLHWKAAAALNYLLFRGGPASSNLIEGGAF
CCCCCCCHHHCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCEECCCEE
WWGNKNETVPDVQFFMVVGAGIEEGVDTVPGGNGCTVNLGQIRPRSRGEVTLQSANPAEN
EECCCCCCCCCEEEEEEECCCHHHCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCC
PRVAPRYFSDPYDLDAVTEGTMAALDIMEKPAISRYIAARQTPAPTMKTRSDIRNFCLET
CCCCCCCCCCCCCCCHHCCCHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
AHAALHPAGTCRMGQDEMAVVGPDLRVRGIDGLRVADASVMPTLISGNPNAVCIMIGERA
HHHHCCCCCCCCCCCCCEEEECCCEEEECCCCCEEECCCCCCEEECCCCCEEEEEECCHH
ASFLSEAA
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9023923 [H]