Click here to switch to the map view.

The map label for this gene is cyaA [H]

Identifier: 13475404

GI number: 13475404

Start: 5279519

End: 5280964

Strand: Reverse

Name: cyaA [H]

Synonym: mll6463

Alternate gene names: 13475404

Gene position: 5280964-5279519 (Counterclockwise)

Preceding gene: 13475405

Following gene: 13475403

Centisome position: 75.06

GC content: 60.93

Gene sequence:

>1446_bases
GTGACGCTAGTCGACGATCGTCTTCTCGAAAGCAAGATGACCAAGGTGGAGCAGGCGCGAGCCTGGAGCCCACGCGTGAT
CTCGAAATTCGAGACGCTGATCAAGAGCGCCGACGACCACTCACTCTATCGCGTTAATCCGCTGGCCTTTGCTCGCGACC
GCGCAATCGCCGAGGCTGAAGCAATCGACCTCTTCCTTCATGCCGCCCGCTGTGGCTTGTTCGACATGAGCTGGGATGTG
CTGTGTCCCCAGTCCGGGATGGTGCTCGACAGTTTCGGCGCCCTGCGCACGCTGAAGACCCACTACGTCTGTGGCCTGTG
CGACGTATCGGGCGACACCGACCTCGACGACTTCATCGAGGTCACCTTCTCGGTATCGCCGAAATTACGGCGCCTGCCTT
ACCACGATCCCGAGACACTCCCTGTTGAGGATTTTCACTGGAAGCTCCACTTCGGACATGACGGGCGGCTACCGGGGCAA
GACGTTCGCTTTCTAGACGTTCTGCGCGGCTTCGTTCGGGGCATGACGTTTCTGCCGCCCGGCACCACCACAGTGCTCCG
CGCCGACCTGGGACCGGGCGCCCTTTCTGGCGTCAACGTCCAGACCCAGGCCGCATTCGCTGTGCCAATATCAGGCGATC
GGGGGTTGGCGCCGACACTTCTGAAGATCGATTATGACGGCAAACGCTTCTTGCCGGCGATGCCCGCTGTGCCACCTGGC
CCGATTGTCATCGAGGTAGCGAATAGAGGGCCAGTGCGGGGTTCGTTGCTTGTCATCAACTGGCCGCCCGAGCTTGTTGC
GCTGACCACCAAGCCGACGCTCGATTTCGACCCTTATGTTTCCGGCGGAGCGCTGCTTGCACGGCAAACCTTCCGCCAGC
TCTTCCGGTCCGAACGTGTCGACGAGAAGGAGGGGCTCGGCATCCGGCAGATCACCTTCCTGTTCACGGACCTCAAGGGT
TCGACCGCCATGTATGAGCGCTTGGGTGACCTCAACGCCTATGCTTTGGTCCGCGAGCATTTCGCACTGGTCAACGCGGC
GGTTCAGCAACATTCCGGAGCGGTGGTCAAGACGATTGGGGATGCGGTGATGGCTGTATTCTCGCAGCCGTCGGATGCGA
TTTCGGCCGCACTCCACGTCTTTGAAGAAATCGATCGCTTCAATGGCGACCATGACGGGCCGGGGATCATCCTCAAGATC
GGCGCCCACTGTGGACCGTCGATCGCCGTGACCCTCAACGACAACCTCGATTATTTCGGCCAGACCGTGAATGTCGCCGC
GCGCGTGCAGTCCTTGGCGGAAGCCGGACAGATCTGCATTTCCGAGGCGCTCTATTCCGCGCCCGGGGTTCGCGAAATGC
TTGCCGGCCATCGTGTCGTTGCTTTTGACGCGCCTCTTCGGGGTGTGCAGGGTGACGCAACCGTCTATCGCATCATGCGC
GAATAG

Upstream 100 bases:

>100_bases
AAGCATCTCTGCTGTGACGGCAGACTCCTTCGACGGCAATCCATTCGCATCGCGCCCGTTTTTTAGTAGGCTGTCGCAAG
GCAAGGTTTGAGGATCCGGC

Downstream 100 bases:

>100_bases
ACACCATTGCGTGCCAACGCCATTTCGCACCGCCTAGGAACCGGAACTTAGGGCCTCCGTCAAGGTCTTGAGCAGTTCGA
TGGGATAGACTGGTGCTGCG

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase 1; Adenylyl cyclase 1; AC 1 [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTLVDDRLLESKMTKVEQARAWSPRVISKFETLIKSADDHSLYRVNPLAFARDRAIAEAEAIDLFLHAARCGLFDMSWDV
LCPQSGMVLDSFGALRTLKTHYVCGLCDVSGDTDLDDFIEVTFSVSPKLRRLPYHDPETLPVEDFHWKLHFGHDGRLPGQ
DVRFLDVLRGFVRGMTFLPPGTTTVLRADLGPGALSGVNVQTQAAFAVPISGDRGLAPTLLKIDYDGKRFLPAMPAVPPG
PIVIEVANRGPVRGSLLVINWPPELVALTTKPTLDFDPYVSGGALLARQTFRQLFRSERVDEKEGLGIRQITFLFTDLKG
STAMYERLGDLNAYALVREHFALVNAAVQQHSGAVVKTIGDAVMAVFSQPSDAISAALHVFEEIDRFNGDHDGPGIILKI
GAHCGPSIAVTLNDNLDYFGQTVNVAARVQSLAEAGQICISEALYSAPGVREMLAGHRVVAFDAPLRGVQGDATVYRIMR
E

Sequences:

>Translated_481_residues
MTLVDDRLLESKMTKVEQARAWSPRVISKFETLIKSADDHSLYRVNPLAFARDRAIAEAEAIDLFLHAARCGLFDMSWDV
LCPQSGMVLDSFGALRTLKTHYVCGLCDVSGDTDLDDFIEVTFSVSPKLRRLPYHDPETLPVEDFHWKLHFGHDGRLPGQ
DVRFLDVLRGFVRGMTFLPPGTTTVLRADLGPGALSGVNVQTQAAFAVPISGDRGLAPTLLKIDYDGKRFLPAMPAVPPG
PIVIEVANRGPVRGSLLVINWPPELVALTTKPTLDFDPYVSGGALLARQTFRQLFRSERVDEKEGLGIRQITFLFTDLKG
STAMYERLGDLNAYALVREHFALVNAAVQQHSGAVVKTIGDAVMAVFSQPSDAISAALHVFEEIDRFNGDHDGPGIILKI
GAHCGPSIAVTLNDNLDYFGQTVNVAARVQSLAEAGQICISEALYSAPGVREMLAGHRVVAFDAPLRGVQGDATVYRIMR
E
>Mature_480_residues
TLVDDRLLESKMTKVEQARAWSPRVISKFETLIKSADDHSLYRVNPLAFARDRAIAEAEAIDLFLHAARCGLFDMSWDVL
CPQSGMVLDSFGALRTLKTHYVCGLCDVSGDTDLDDFIEVTFSVSPKLRRLPYHDPETLPVEDFHWKLHFGHDGRLPGQD
VRFLDVLRGFVRGMTFLPPGTTTVLRADLGPGALSGVNVQTQAAFAVPISGDRGLAPTLLKIDYDGKRFLPAMPAVPPGP
IVIEVANRGPVRGSLLVINWPPELVALTTKPTLDFDPYVSGGALLARQTFRQLFRSERVDEKEGLGIRQITFLFTDLKGS
TAMYERLGDLNAYALVREHFALVNAAVQQHSGAVVKTIGDAVMAVFSQPSDAISAALHVFEEIDRFNGDHDGPGIILKIG
AHCGPSIAVTLNDNLDYFGQTVNVAARVQSLAEAGQICISEALYSAPGVREMLAGHRVVAFDAPLRGVQGDATVYRIMRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 guanylate cyclase domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322455, Length=192, Percent_Identity=29.6875, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054 [H]

Pfam domain/function: PF00211 Guanylate_cyc [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 52580; Mature: 52449

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVDDRLLESKMTKVEQARAWSPRVISKFETLIKSADDHSLYRVNPLAFARDRAIAEAE
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHH
AIDLFLHAARCGLFDMSWDVLCPQSGMVLDSFGALRTLKTHYVCGLCDVSGDTDLDDFIE
HHHHHHHHHHCCCEECCCCEECCCCCCEEECHHHHHHHHHHEEEEEEECCCCCCHHHHHE
VTFSVSPKLRRLPYHDPETLPVEDFHWKLHFGHDGRLPGQDVRFLDVLRGFVRGMTFLPP
EEEECCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEECCC
GTTTVLRADLGPGALSGVNVQTQAAFAVPISGDRGLAPTLLKIDYDGKRFLPAMPAVPPG
CCCEEEEECCCCCCCCCCCEEECEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCC
PIVIEVANRGPVRGSLLVINWPPELVALTTKPTLDFDPYVSGGALLARQTFRQLFRSERV
CEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
DEKEGLGIRQITFLFTDLKGSTAMYERLGDLNAYALVREHFALVNAAVQQHSGAVVKTIG
CHHHCCCCEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DAVMAVFSQPSDAISAALHVFEEIDRFNGDHDGPGIILKIGAHCGPSIAVTLNDNLDYFG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCHHHHC
QTVNVAARVQSLAEAGQICISEALYSAPGVREMLAGHRVVAFDAPLRGVQGDATVYRIMR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCCCCCCHHHHHEEC
E
C
>Mature Secondary Structure 
TLVDDRLLESKMTKVEQARAWSPRVISKFETLIKSADDHSLYRVNPLAFARDRAIAEAE
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHH
AIDLFLHAARCGLFDMSWDVLCPQSGMVLDSFGALRTLKTHYVCGLCDVSGDTDLDDFIE
HHHHHHHHHHCCCEECCCCEECCCCCCEEECHHHHHHHHHHEEEEEEECCCCCCHHHHHE
VTFSVSPKLRRLPYHDPETLPVEDFHWKLHFGHDGRLPGQDVRFLDVLRGFVRGMTFLPP
EEEECCCHHHCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCEEECCC
GTTTVLRADLGPGALSGVNVQTQAAFAVPISGDRGLAPTLLKIDYDGKRFLPAMPAVPPG
CCCEEEEECCCCCCCCCCCEEECEEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCC
PIVIEVANRGPVRGSLLVINWPPELVALTTKPTLDFDPYVSGGALLARQTFRQLFRSERV
CEEEEECCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
DEKEGLGIRQITFLFTDLKGSTAMYERLGDLNAYALVREHFALVNAAVQQHSGAVVKTIG
CHHHCCCCEEEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
DAVMAVFSQPSDAISAALHVFEEIDRFNGDHDGPGIILKIGAHCGPSIAVTLNDNLDYFG
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEECCCHHHHC
QTVNVAARVQSLAEAGQICISEALYSAPGVREMLAGHRVVAFDAPLRGVQGDATVYRIMR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCEEEEECCCCCCCCCCHHHHHEEC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9523018; 8418825 [H]