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The map label for this gene is murA1

Identifier: 13475402

GI number: 13475402

Start: 5277592

End: 5278884

Strand: Reverse

Name: murA1

Synonym: mll6459

Alternate gene names: 13475402

Gene position: 5278884-5277592 (Counterclockwise)

Preceding gene: 13475403

Following gene: 13475400

Centisome position: 75.03

GC content: 64.5

Gene sequence:

>1293_bases
ATGGATCGCATCAGAATTGTCGGCGGCAACAAGCTTGCCGGAAGCATTCCGATCTCGGGCGCGAAAAACGCCGCTTTGCC
GCTGATGATCGCCTCGCTTTTGACCGACGACACGCTGACGCTGGAAAACGTGCCGCATCTGGCCGATGTCGAGCAGCTGA
TCCGCATCCTCGGCAATCACGGCGTCGATTACTCGGTCAATGGCCGCCGCGAGAAGCAGAATGAAGGCTATTCGCGCACC
ATCAACTTCTCCGCCCGCAACATCGTCGACACGACGGCGCCTTACGAGCTGGTGTCGAAGATGCGGGCGTCGTTCTGGGT
GATCGGCCCGCTGCTGGCCCGCATGGGCGAGGCCAAGGTGTCGCTGCCCGGCGGCTGCGCCATCGGCACGCGCCCGGTTG
ACCTGTTCCTCGAAGGCCTGCAGGCGCTTGGCGCCGATCTCGATGTTGACACCGGCTATGTCATCGCCAAGACCAAGAAT
GGTCGCCTGGTCGGCAACCGCTATGTCTTCCCCAAGGTCTCGGTCGGCGCCACCCATGTGCTTATGATGGCGGCTTCGCT
GGCCAAGGGCGAGACAGTGCTGGAAAACGCCGCCTGCGAGCCTGAAATCGTCAACCTCGCCGAATGCCTCAACGCCATGG
GCGCCAGGATTTCCGGCGCCGGTACACCGACCATCACCATCGATGGCGTCGAATCGCTGTCGGGCGCGCGCGTGCGCGTC
ATTCCCGACCGCATCGAGACCGGCACCTATGCCATGGCGGTCGCCATGACGGGCGGCGACGTCGTGCTCGAAGGCGCGCG
GCCGGAGCTGCTGCAGACCGCGCTGGACGTGATTTCGCAGACGGGTGCCGAGATCACCCAGACCAATTCCGGTATTCGCG
TGAAGCGCAACGGCGCCGGCATTTCGCCCGTCGATGTGACCACGGCGCCCTTCCCGGCCTTCCCGACCGATCTGCAGGCG
CAGTTCATGGGCCTGATGACCATGGCCAAGGGTAAGTCGCGCATCACCGAGACGATCTTCGAGAACCGCTTCATGCACGT
CCAGGAACTGGCCCGGCTCGGCGCCCACATCACGCTTTCGGGCCAGACGGCGATCGTCGACGGCGTGGCGAAGTTGAAAG
GCGCGCCGGTCATGGCCACCGACCTTCGCGCTTCCGTCTCGCTGGTCATCGCCGGCCTCGCTGCCGAAGGCGAGACCACG
GTCAACCGCGTCTACCATCTCGACCGCGGCTTCGAGCGGCTGGAGGAAAAACTGTCCAACTGCGGCGCGGTGATCGAGCG
CATTTCCGCCTGA

Upstream 100 bases:

>100_bases
CGTGGAAATCCTATTTCTTGAACCACACCGGCCAATGGTCTAGACGGGCCGATACTCAAACGATTGAACCGGCCTTTTTG
GCCGAGAGGGATATTCTCCA

Downstream 100 bases:

>100_bases
CGATCGAACGGCGGCAGCTTCGAACGGAGGCTGCCCGTGCGGCCTTCATCCACCTGCCAGCACCGCAAAGCCGAGGCAAT
TGCCTCGGGCGGGAGTCGTG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 1; UDP-N-acetylglucosamine enolpyruvyl transferase 1; EPT 1

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MDRIRIVGGNKLAGSIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGVDYSVNGRREKQNEGYSRT
INFSARNIVDTTAPYELVSKMRASFWVIGPLLARMGEAKVSLPGGCAIGTRPVDLFLEGLQALGADLDVDTGYVIAKTKN
GRLVGNRYVFPKVSVGATHVLMMAASLAKGETVLENAACEPEIVNLAECLNAMGARISGAGTPTITIDGVESLSGARVRV
IPDRIETGTYAMAVAMTGGDVVLEGARPELLQTALDVISQTGAEITQTNSGIRVKRNGAGISPVDVTTAPFPAFPTDLQA
QFMGLMTMAKGKSRITETIFENRFMHVQELARLGAHITLSGQTAIVDGVAKLKGAPVMATDLRASVSLVIAGLAAEGETT
VNRVYHLDRGFERLEEKLSNCGAVIERISA

Sequences:

>Translated_430_residues
MDRIRIVGGNKLAGSIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGVDYSVNGRREKQNEGYSRT
INFSARNIVDTTAPYELVSKMRASFWVIGPLLARMGEAKVSLPGGCAIGTRPVDLFLEGLQALGADLDVDTGYVIAKTKN
GRLVGNRYVFPKVSVGATHVLMMAASLAKGETVLENAACEPEIVNLAECLNAMGARISGAGTPTITIDGVESLSGARVRV
IPDRIETGTYAMAVAMTGGDVVLEGARPELLQTALDVISQTGAEITQTNSGIRVKRNGAGISPVDVTTAPFPAFPTDLQA
QFMGLMTMAKGKSRITETIFENRFMHVQELARLGAHITLSGQTAIVDGVAKLKGAPVMATDLRASVSLVIAGLAAEGETT
VNRVYHLDRGFERLEEKLSNCGAVIERISA
>Mature_430_residues
MDRIRIVGGNKLAGSIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNHGVDYSVNGRREKQNEGYSRT
INFSARNIVDTTAPYELVSKMRASFWVIGPLLARMGEAKVSLPGGCAIGTRPVDLFLEGLQALGADLDVDTGYVIAKTKN
GRLVGNRYVFPKVSVGATHVLMMAASLAKGETVLENAACEPEIVNLAECLNAMGARISGAGTPTITIDGVESLSGARVRV
IPDRIETGTYAMAVAMTGGDVVLEGARPELLQTALDVISQTGAEITQTNSGIRVKRNGAGISPVDVTTAPFPAFPTDLQA
QFMGLMTMAKGKSRITETIFENRFMHVQELARLGAHITLSGQTAIVDGVAKLKGAPVMATDLRASVSLVIAGLAAEGETT
VNRVYHLDRGFERLEEKLSNCGAVIERISA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=429, Percent_Identity=50.3496503496504, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA1_RHILO (Q989E5)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_106966.1
- ProteinModelPortal:   Q989E5
- SMR:   Q989E5
- GeneID:   1229621
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll6459
- NMPDR:   fig|266835.1.peg.5067
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BRENDA:   2.5.1.7
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 45536; Mature: 45536

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: NA

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRIRIVGGNKLAGSIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNH
CCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCC
GVDYSVNGRREKQNEGYSRTINFSARNIVDTTAPYELVSKMRASFWVIGPLLARMGEAKV
CCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDLFLEGLQALGADLDVDTGYVIAKTKNGRLVGNRYVFPKVSVGATHV
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECEEECCCCCCCHHHH
LMMAASLAKGETVLENAACEPEIVNLAECLNAMGARISGAGTPTITIDGVESLSGARVRV
HHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHCCEECCCCCCEEEECCCCCCCCCEEEE
IPDRIETGTYAMAVAMTGGDVVLEGARPELLQTALDVISQTGAEITQTNSGIRVKRNGAG
ECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCC
ISPVDVTTAPFPAFPTDLQAQFMGLMTMAKGKSRITETIFENRFMHVQELARLGAHITLS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GQTAIVDGVAKLKGAPVMATDLRASVSLVIAGLAAEGETTVNRVYHLDRGFERLEEKLSN
CCHHHHHHHHHHCCCCEEEHHHHHHEEHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
CGAVIERISA
HHHHHHHHCC
>Mature Secondary Structure
MDRIRIVGGNKLAGSIPISGAKNAALPLMIASLLTDDTLTLENVPHLADVEQLIRILGNH
CCCEEEECCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCHHHHHHHHCCC
GVDYSVNGRREKQNEGYSRTINFSARNIVDTTAPYELVSKMRASFWVIGPLLARMGEAKV
CCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
SLPGGCAIGTRPVDLFLEGLQALGADLDVDTGYVIAKTKNGRLVGNRYVFPKVSVGATHV
ECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECEEECCCCCCCHHHH
LMMAASLAKGETVLENAACEPEIVNLAECLNAMGARISGAGTPTITIDGVESLSGARVRV
HHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHCCEECCCCCCEEEECCCCCCCCCEEEE
IPDRIETGTYAMAVAMTGGDVVLEGARPELLQTALDVISQTGAEITQTNSGIRVKRNGAG
ECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCC
ISPVDVTTAPFPAFPTDLQAQFMGLMTMAKGKSRITETIFENRFMHVQELARLGAHITLS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GQTAIVDGVAKLKGAPVMATDLRASVSLVIAGLAAEGETTVNRVYHLDRGFERLEEKLSN
CCHHHHHHHHHHCCCCEEEHHHHHHEEHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
CGAVIERISA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968