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The map label for this gene is melR [H]

Identifier: 13475382

GI number: 13475382

Start: 5256160

End: 5257032

Strand: Reverse

Name: melR [H]

Synonym: mll6433

Alternate gene names: 13475382

Gene position: 5257032-5256160 (Counterclockwise)

Preceding gene: 13475388

Following gene: 13475381

Centisome position: 74.72

GC content: 62.43

Gene sequence:

>873_bases
ATGCCGGAACGGCCGTTTTACCAGCCGGGCGCCAGCAGCGTGGAGGGCCTGCCGCTGCTCTTGCAGATGTTTCACACCGC
TCCGCTGGTGATGCTCAAGCCGCACTGGCATGCCCAGGTCGAGGTGAATTTCATCGTCCGCGGCAGCGTGCACTACCGCA
TGAACGAGCACGAAATCTCCCTGTCGGCCGGCGAGATGTGCTTCTTCTGGGGTGGCCTGCCGCACCAGATGGACGATCTC
AGCGACGACGCCATCTATGCCGGCGCGCATCTGCCACTGGTGCATTTCTTCCGGCTGCATCTGCCGGCGGACGTGCGCCA
CCGGCTGATGACGGGCGCGACGCTGGTGACCAGCGCCACCGATCAATCCGACAACGACAATTTCGCCCGCTGGAACCGCT
ATGCCCGCTCGGGCGATCCGGCCAAGGCCGAGCATGCCGTCAACGAATTGTTGCTGCGGTTGGAGCGGGTGCGGTTCGAA
CCCTACCGGCTGGTGCCAGAGACGGCGGCCGGGCAGGAAGCCGGCAGTGCCTTCGACCAGCAGTCCTCGCGCAATGTCGG
GCGCATGTGCGATTTCATCGCCGAGAATTTTCTCTACGACATCGATTGTATGAACATAGCGGCCGCCGCCGACATCCATC
CCAAATACGCCATGAGCCTGTTCAAGAAATCGACCGGTATGACGCTCAACGAATATGTCAATCTTCTGCGGCTGAGCTAC
GCGCAGGCGCTCTTGATGCATCAGGACGCCAATGTGCTGCGCGTCGCCATGGACTCCGGTTTCGGCTCGCTCAGTGCCTT
CAACAAGTCCTTCCGCAAGCTGGCCGGCATGACGCCCTCCGATTTTCGCAGGAGCGTGGCCAGCGCCAGGTAG

Upstream 100 bases:

>100_bases
ATCCTCCCATTTCATTTGCTCTCTCTGCGAGCGTGGCTACACTATTCGGCGCGGAAGGCTTGTCGCCGACAAAGGGAATA
CGGAATTGGCGGAAAGTAAG

Downstream 100 bases:

>100_bases
AAGCGACGGTCGGTTGCTCGTTGAGGCGAATGCACAGCGGCATCCCGATCGTCGGCTAAGGACGGACCCCGGCGGTCGCA
GCGCGGTTTGGCGGCGCCGG

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MPERPFYQPGASSVEGLPLLLQMFHTAPLVMLKPHWHAQVEVNFIVRGSVHYRMNEHEISLSAGEMCFFWGGLPHQMDDL
SDDAIYAGAHLPLVHFFRLHLPADVRHRLMTGATLVTSATDQSDNDNFARWNRYARSGDPAKAEHAVNELLLRLERVRFE
PYRLVPETAAGQEAGSAFDQQSSRNVGRMCDFIAENFLYDIDCMNIAAAADIHPKYAMSLFKKSTGMTLNEYVNLLRLSY
AQALLMHQDANVLRVAMDSGFGSLSAFNKSFRKLAGMTPSDFRRSVASAR

Sequences:

>Translated_290_residues
MPERPFYQPGASSVEGLPLLLQMFHTAPLVMLKPHWHAQVEVNFIVRGSVHYRMNEHEISLSAGEMCFFWGGLPHQMDDL
SDDAIYAGAHLPLVHFFRLHLPADVRHRLMTGATLVTSATDQSDNDNFARWNRYARSGDPAKAEHAVNELLLRLERVRFE
PYRLVPETAAGQEAGSAFDQQSSRNVGRMCDFIAENFLYDIDCMNIAAAADIHPKYAMSLFKKSTGMTLNEYVNLLRLSY
AQALLMHQDANVLRVAMDSGFGSLSAFNKSFRKLAGMTPSDFRRSVASAR
>Mature_289_residues
PERPFYQPGASSVEGLPLLLQMFHTAPLVMLKPHWHAQVEVNFIVRGSVHYRMNEHEISLSAGEMCFFWGGLPHQMDDLS
DDAIYAGAHLPLVHFFRLHLPADVRHRLMTGATLVTSATDQSDNDNFARWNRYARSGDPAKAEHAVNELLLRLERVRFEP
YRLVPETAAGQEAGSAFDQQSSRNVGRMCDFIAENFLYDIDCMNIAAAADIHPKYAMSLFKKSTGMTLNEYVNLLRLSYA
QALLMHQDANVLRVAMDSGFGSLSAFNKSFRKLAGMTPSDFRRSVASAR

Specific function: Transcription activator for the expression of the melAB operon. MelR binds at two sites located upstream of the melAB transcription site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790559, Length=258, Percent_Identity=27.906976744186, Blast_Score=136, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008917
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- InterPro:   IPR014710 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 32612; Mature: 32480

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERPFYQPGASSVEGLPLLLQMFHTAPLVMLKPHWHAQVEVNFIVRGSVHYRMNEHEIS
CCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEEEEEEEECCCEEE
LSAGEMCFFWGGLPHQMDDLSDDAIYAGAHLPLVHFFRLHLPADVRHRLMTGATLVTSAT
ECCCCEEEEECCCCCHHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHCCHHEEECC
DQSDNDNFARWNRYARSGDPAKAEHAVNELLLRLERVRFEPYRLVPETAAGQEAGSAFDQ
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHH
QSSRNVGRMCDFIAENFLYDIDCMNIAAAADIHPKYAMSLFKKSTGMTLNEYVNLLRLSY
HHCCCHHHHHHHHHHHHEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
AQALLMHQDANVLRVAMDSGFGSLSAFNKSFRKLAGMTPSDFRRSVASAR
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure 
PERPFYQPGASSVEGLPLLLQMFHTAPLVMLKPHWHAQVEVNFIVRGSVHYRMNEHEIS
CCCCCCCCCCCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEEEEEEEEEEEECCCEEE
LSAGEMCFFWGGLPHQMDDLSDDAIYAGAHLPLVHFFRLHLPADVRHRLMTGATLVTSAT
ECCCCEEEEECCCCCHHHCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHHCCHHEEECC
DQSDNDNFARWNRYARSGDPAKAEHAVNELLLRLERVRFEPYRLVPETAAGQEAGSAFDQ
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCHHHHHHHH
QSSRNVGRMCDFIAENFLYDIDCMNIAAAADIHPKYAMSLFKKSTGMTLNEYVNLLRLSY
HHCCCHHHHHHHHHHHHEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
AQALLMHQDANVLRVAMDSGFGSLSAFNKSFRKLAGMTPSDFRRSVASAR
HHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]