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The map label for this gene is msmR [H]

Identifier: 13475388

GI number: 13475388

Start: 5263363

End: 5264418

Strand: Reverse

Name: msmR [H]

Synonym: mll6442

Alternate gene names: 13475388

Gene position: 5264418-5263363 (Counterclockwise)

Preceding gene: 13475395

Following gene: 13475382

Centisome position: 74.82

GC content: 62.78

Gene sequence:

>1056_bases
ATGGCATGTGTGCGGGACAAGCCGGTTTCCGGCCCGCCAACCTCCCTGTCCGCTCCTCACCTGCGGATCTCTCTCGCTTT
TCGAGGGGGATTATGCCCTTATTCACGAGCGCGACCAGAGAAGGATTATGCTTTCAAGGGTAATTTTGTGCTACGAGATT
TGATCGCCAACGGACAGTCGATGCGCACGATCTCGCTGCCGCGCGGCCGGCAGCGCCTGCATGCCATGCCGACAAGCACC
GGCTATGAAGTGCGCGAGGACGAGATCTATGACTGGGACGGGCGTAAACGCGGCCAGACGCCGTTCACCGTGCTCCAGCA
CACGATCAGCGGCACCGGCCGGCTACGCTACGAGAACCGCAACTACCGCCTGCAAGAGAACGACACGCTGCTGGTGCTGG
TGCCGCACAACCACCGCTACTGGCTGGCCAGCGACGAGCGCTGGGAATATTTCTGGATCTCGATGAACGGCGAGGAGGCG
CTGCGCATCCACAAGTCGATCCTCAGCATCTCCGGTCCGGTGTTCCGGCTTAAGCCAGCGACGATCGATCACCTTGCTGA
TTGCAGCCTGCGCCTCATCAACGGGGCGGCCTCGGCGGGTGCCGCGTCCGCTATCGCCTACGAGGCGGCGATGGCGCTCT
ATGACGATGTCTTCGGCTCGCATGCCTTTGCCGAGAAACTGAGCGCCATGCAGCCGGTCATCGACCATATCAACGCCAAT
CTCGACAGGCCGCTGCCGGTGGCGGACCTCGTCCAGATCAGTGGCCTCAGCCGCGCCCATTTCTCGCGCTGCTTCGCCGA
GAGCGAAGGCCTGCCGCCCGCCGAATTCGTGTTGCAGCAGCGCCTGCAGCGGGCGGCGAAGCTGTTGACCAAGGCGGATT
TTCTGCCGGTGAAGGAAGTCGCCATCCTGTGCGGCTTCGAGGATGCGAACTATTTTTCGAAGGTCTTCCGCCGTCTCTAC
GGCACCACGCCCAGCCAATTCCGCACCACCGGCATGTATGCCAATCTGCGAACGCCGGCCAGGCGCGGCGTCAGGGTGTC
GGACGACGAGACCTGA

Upstream 100 bases:

>100_bases
TGCCGGCACCGATGATAGCGATTTTGAAACTCATCAGCCGTACCTCATCCTATTCCAATGGCAGGCCGGGAATGACAGCG
GTAGGTCGCAGCCGCATGCC

Downstream 100 bases:

>100_bases
CGCCGCTTTGAGTTCCATCAGGCCGCGTGCAGGCTGCCGCCGTCCAGCCACTCGAGATCGGCAGGCGAAAGCGCGATGTC
CAGCGCCCGCAGACTGTCTT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MACVRDKPVSGPPTSLSAPHLRISLAFRGGLCPYSRARPEKDYAFKGNFVLRDLIANGQSMRTISLPRGRQRLHAMPTST
GYEVREDEIYDWDGRKRGQTPFTVLQHTISGTGRLRYENRNYRLQENDTLLVLVPHNHRYWLASDERWEYFWISMNGEEA
LRIHKSILSISGPVFRLKPATIDHLADCSLRLINGAASAGAASAIAYEAAMALYDDVFGSHAFAEKLSAMQPVIDHINAN
LDRPLPVADLVQISGLSRAHFSRCFAESEGLPPAEFVLQQRLQRAAKLLTKADFLPVKEVAILCGFEDANYFSKVFRRLY
GTTPSQFRTTGMYANLRTPARRGVRVSDDET

Sequences:

>Translated_351_residues
MACVRDKPVSGPPTSLSAPHLRISLAFRGGLCPYSRARPEKDYAFKGNFVLRDLIANGQSMRTISLPRGRQRLHAMPTST
GYEVREDEIYDWDGRKRGQTPFTVLQHTISGTGRLRYENRNYRLQENDTLLVLVPHNHRYWLASDERWEYFWISMNGEEA
LRIHKSILSISGPVFRLKPATIDHLADCSLRLINGAASAGAASAIAYEAAMALYDDVFGSHAFAEKLSAMQPVIDHINAN
LDRPLPVADLVQISGLSRAHFSRCFAESEGLPPAEFVLQQRLQRAAKLLTKADFLPVKEVAILCGFEDANYFSKVFRRLY
GTTPSQFRTTGMYANLRTPARRGVRVSDDET
>Mature_350_residues
ACVRDKPVSGPPTSLSAPHLRISLAFRGGLCPYSRARPEKDYAFKGNFVLRDLIANGQSMRTISLPRGRQRLHAMPTSTG
YEVREDEIYDWDGRKRGQTPFTVLQHTISGTGRLRYENRNYRLQENDTLLVLVPHNHRYWLASDERWEYFWISMNGEEAL
RIHKSILSISGPVFRLKPATIDHLADCSLRLINGAASAGAASAIAYEAAMALYDDVFGSHAFAEKLSAMQPVIDHINANL
DRPLPVADLVQISGLSRAHFSRCFAESEGLPPAEFVLQQRLQRAAKLLTKADFLPVKEVAILCGFEDANYFSKVFRRLYG
TTPSQFRTTGMYANLRTPARRGVRVSDDET

Specific function: Regulatory protein for the msm operon for multiple sugar metabolism. Activates the transcription of the msmEFGK, aga, dexB and gftA genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786251, Length=243, Percent_Identity=27.9835390946502, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 39462; Mature: 39331

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACVRDKPVSGPPTSLSAPHLRISLAFRGGLCPYSRARPEKDYAFKGNFVLRDLIANGQS
CCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHCCCCCCCEEECCHHHHHHHHCCCC
MRTISLPRGRQRLHAMPTSTGYEVREDEIYDWDGRKRGQTPFTVLQHTISGTGRLRYENR
EEEEECCCCHHHHHCCCCCCCCEECCCCEECCCCCCCCCCHHHHHHHHHCCCEEEEECCC
NYRLQENDTLLVLVPHNHRYWLASDERWEYFWISMNGEEALRIHKSILSISGPVFRLKPA
CEEEECCCEEEEEEECCCEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCEEEECCC
TIDHLADCSLRLINGAASAGAASAIAYEAAMALYDDVFGSHAFAEKLSAMQPVIDHINAN
CHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
LDRPLPVADLVQISGLSRAHFSRCFAESEGLPPAEFVLQQRLQRAAKLLTKADFLPVKEV
CCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHE
AILCGFEDANYFSKVFRRLYGTTPSQFRTTGMYANLRTPARRGVRVSDDET
EEEECCCCCHHHHHHHHHHHCCCHHHHEECCEEEECCCHHHCCCCCCCCCC
>Mature Secondary Structure 
ACVRDKPVSGPPTSLSAPHLRISLAFRGGLCPYSRARPEKDYAFKGNFVLRDLIANGQS
CCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCHHCCCCCCCEEECCHHHHHHHHCCCC
MRTISLPRGRQRLHAMPTSTGYEVREDEIYDWDGRKRGQTPFTVLQHTISGTGRLRYENR
EEEEECCCCHHHHHCCCCCCCCEECCCCEECCCCCCCCCCHHHHHHHHHCCCEEEEECCC
NYRLQENDTLLVLVPHNHRYWLASDERWEYFWISMNGEEALRIHKSILSISGPVFRLKPA
CEEEECCCEEEEEEECCCEEEEECCCCEEEEEEEECCHHHHHHHHHHHHCCCCEEEECCC
TIDHLADCSLRLINGAASAGAASAIAYEAAMALYDDVFGSHAFAEKLSAMQPVIDHINAN
CHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCC
LDRPLPVADLVQISGLSRAHFSRCFAESEGLPPAEFVLQQRLQRAAKLLTKADFLPVKEV
CCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHE
AILCGFEDANYFSKVFRRLYGTTPSQFRTTGMYANLRTPARRGVRVSDDET
EEEECCCCCHHHHHHHHHHHCCCHHHHEECCEEEECCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537846; 12397186 [H]