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The map label for this gene is 13475325

Identifier: 13475325

GI number: 13475325

Start: 5189213

End: 5190502

Strand: Direct

Name: 13475325

Synonym: mlr6365

Alternate gene names: NA

Gene position: 5189213-5190502 (Clockwise)

Preceding gene: 13475324

Following gene: 13475326

Centisome position: 73.75

GC content: 66.82

Gene sequence:

>1290_bases
ATGGACGTGCAAGAAACCACGGCAGCATGCCGGGACGCCTTCGCCGAACTTGCGTCGCCAGCGTGTATCCAAGACCCGTA
TACGTTCATGCGGTGGTTGCGCGAGCACGATCCGGTGCATCGTGCGGCGTCGGGCCTCTTTCTGTTGAGCCGCCACGCCG
ACATCTACTGGGCGCTCAAGGCCACGGGCGATGTGTTTCGGGGACCGGCGCCGGGCGAACTGGCGCGCTATTTCCCGCGT
GCGGAGACCAGCCTGTCACTCAATCTCCTCGCGTCCACGCTAGCGATGAAGGAACCACCGACGCATACGCGTCTGCGCCG
GCTGATCTCGCGCGATTTCACCATACGCCAGATCGACAACCTGCGGCCGAGCATCGCACGCATCGTCGCAGCGCGCCTGG
ACGGCATGGCGCCCGCGCTGGAGCGCGGGGAGGCGGTGGACCTGCATTGGGAATTCGCGCTGGCTGTGCCCATTCTGGTC
TTCGCCGAACTGTTCGGCATGCCCCAGGATGACATGTTCGGGCTCGCCGCCGGCATCGGCGCCATTCTGGAAGGCCTGAG
CCCACACGCCAGCGATCCCCAGCTCGCCGAGGCGGACGCGGCCAGCGCGAGGGTGCAGGCCTACTTCGGCGACCTCATAC
AGCGCAAGCGCACCGATCCCCGCAACGACATCGTGTCGATGGTGGTCGGCGCACACGACGACGATGCCGACACGCTGTCG
GATGCGGAGTTGATCAGCATGCTGTGGGGCATGCTGCTGGGCGGCTTCGCCACCACTGCTGCGACCATCGACCATGCGGT
CCTAGCGATGCTGGCGTATCCCGAACAGCGGCACTGGCTGCAGGGAGACGCCGTGGGGGTGAAGGCATTCGTCGAAGAAG
TCCTGCGCTGCGACGCGCCTGCCATGTTCAGCTCCATCCCGCGTATCGCCCAGCGCGACATCGAACTGGGCGGCGTGGTG
ATCCCGAAGAACGCGGACGTGCGCGTGCTGATCGCGGCCGGCAATCGCGACCCGGACGCCTTCTCCGATCCCGACCGCTT
CGATCCCGCGCGGTTCTACGGCACCACTCCTGGCATGTCGACCGACGGGAAGATCATGCTGAGCTTTGGCCACGGCATCC
ACTTCTGCCTCGGTGCGCAACTGGCCCGGGTGCAGTTGGCCGAGAGCCTGCCGCGGATCGAGGCGCGCTTCCCCACGCTG
GCATTGGCCGAGCAGCCGACCCGGGAGCCATCCGCGTTCCTCAGGACGTTCCGCGCGCTGCCGGTGCGACTGCATGCTCA
GGGGGGCTGA

Upstream 100 bases:

>100_bases
TGGTGACGCGCGGACGCCGCCCGGAATCGCGATCTACTCCGCAATTTGCCGGCGCGCCCAGCGCGCGCCGGTCAGATCAG
CCAGCCAACAGGTAACCAAG

Downstream 100 bases:

>100_bases
GATGCGCGTCGTGATCGATCAGGATCTATGCGGAACCACCGGGCAGTGTGTGCTGACGCTGCCGGGCACCTTTCGCCAGC
GCGAACCGGACGGCGTGGCG

Product: cytochrome P-450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MDVQETTAACRDAFAELASPACIQDPYTFMRWLREHDPVHRAASGLFLLSRHADIYWALKATGDVFRGPAPGELARYFPR
AETSLSLNLLASTLAMKEPPTHTRLRRLISRDFTIRQIDNLRPSIARIVAARLDGMAPALERGEAVDLHWEFALAVPILV
FAELFGMPQDDMFGLAAGIGAILEGLSPHASDPQLAEADAASARVQAYFGDLIQRKRTDPRNDIVSMVVGAHDDDADTLS
DAELISMLWGMLLGGFATTAATIDHAVLAMLAYPEQRHWLQGDAVGVKAFVEEVLRCDAPAMFSSIPRIAQRDIELGGVV
IPKNADVRVLIAAGNRDPDAFSDPDRFDPARFYGTTPGMSTDGKIMLSFGHGIHFCLGAQLARVQLAESLPRIEARFPTL
ALAEQPTREPSAFLRTFRALPVRLHAQGG

Sequences:

>Translated_429_residues
MDVQETTAACRDAFAELASPACIQDPYTFMRWLREHDPVHRAASGLFLLSRHADIYWALKATGDVFRGPAPGELARYFPR
AETSLSLNLLASTLAMKEPPTHTRLRRLISRDFTIRQIDNLRPSIARIVAARLDGMAPALERGEAVDLHWEFALAVPILV
FAELFGMPQDDMFGLAAGIGAILEGLSPHASDPQLAEADAASARVQAYFGDLIQRKRTDPRNDIVSMVVGAHDDDADTLS
DAELISMLWGMLLGGFATTAATIDHAVLAMLAYPEQRHWLQGDAVGVKAFVEEVLRCDAPAMFSSIPRIAQRDIELGGVV
IPKNADVRVLIAAGNRDPDAFSDPDRFDPARFYGTTPGMSTDGKIMLSFGHGIHFCLGAQLARVQLAESLPRIEARFPTL
ALAEQPTREPSAFLRTFRALPVRLHAQGG
>Mature_429_residues
MDVQETTAACRDAFAELASPACIQDPYTFMRWLREHDPVHRAASGLFLLSRHADIYWALKATGDVFRGPAPGELARYFPR
AETSLSLNLLASTLAMKEPPTHTRLRRLISRDFTIRQIDNLRPSIARIVAARLDGMAPALERGEAVDLHWEFALAVPILV
FAELFGMPQDDMFGLAAGIGAILEGLSPHASDPQLAEADAASARVQAYFGDLIQRKRTDPRNDIVSMVVGAHDDDADTLS
DAELISMLWGMLLGGFATTAATIDHAVLAMLAYPEQRHWLQGDAVGVKAFVEEVLRCDAPAMFSSIPRIAQRDIELGGVV
IPKNADVRVLIAAGNRDPDAFSDPDRFDPARFYGTTPGMSTDGKIMLSFGHGIHFCLGAQLARVQLAESLPRIEARFPTL
ALAEQPTREPSAFLRTFRALPVRLHAQGG

Specific function: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI4503213, Length=206, Percent_Identity=27.1844660194175, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI19743565, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 46887; Mature: 46887

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVQETTAACRDAFAELASPACIQDPYTFMRWLREHDPVHRAASGLFLLSRHADIYWALK
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHEEEECCCCEEEEEE
ATGDVFRGPAPGELARYFPRAETSLSLNLLASTLAMKEPPTHTRLRRLISRDFTIRQIDN
CCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHC
LRPSIARIVAARLDGMAPALERGEAVDLHWEFALAVPILVFAELFGMPQDDMFGLAAGIG
CCHHHHHHHHHHHHCCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AILEGLSPHASDPQLAEADAASARVQAYFGDLIQRKRTDPRNDIVSMVVGAHDDDADTLS
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHH
DAELISMLWGMLLGGFATTAATIDHAVLAMLAYPEQRHWLQGDAVGVKAFVEEVLRCDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCC
AMFSSIPRIAQRDIELGGVVIPKNADVRVLIAAGNRDPDAFSDPDRFDPARFYGTTPGMS
HHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHEECCCCCCC
TDGKIMLSFGHGIHFCLGAQLARVQLAESLPRIEARFPTLALAEQPTREPSAFLRTFRAL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCCHHHHHHHHHHC
PVRLHAQGG
CEEEEECCC
>Mature Secondary Structure
MDVQETTAACRDAFAELASPACIQDPYTFMRWLREHDPVHRAASGLFLLSRHADIYWALK
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHHEEEECCCCEEEEEE
ATGDVFRGPAPGELARYFPRAETSLSLNLLASTLAMKEPPTHTRLRRLISRDFTIRQIDN
CCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHC
LRPSIARIVAARLDGMAPALERGEAVDLHWEFALAVPILVFAELFGMPQDDMFGLAAGIG
CCHHHHHHHHHHHHCCCHHHHCCCEEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
AILEGLSPHASDPQLAEADAASARVQAYFGDLIQRKRTDPRNDIVSMVVGAHDDDADTLS
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHH
DAELISMLWGMLLGGFATTAATIDHAVLAMLAYPEQRHWLQGDAVGVKAFVEEVLRCDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHCCCC
AMFSSIPRIAQRDIELGGVVIPKNADVRVLIAAGNRDPDAFSDPDRFDPARFYGTTPGMS
HHHHHHHHHHHHCCCCCCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCHHEECCCCCCC
TDGKIMLSFGHGIHFCLGAQLARVQLAESLPRIEARFPTLALAEQPTREPSAFLRTFRAL
CCCEEEEEECCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCEECCCCCCCHHHHHHHHHHC
PVRLHAQGG
CEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]