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The map label for this gene is cyp112 [H]

Identifier: 13475324

GI number: 13475324

Start: 5187916

End: 5189118

Strand: Direct

Name: cyp112 [H]

Synonym: mlr6364

Alternate gene names: 13475324

Gene position: 5187916-5189118 (Clockwise)

Preceding gene: 13475322

Following gene: 13475325

Centisome position: 73.73

GC content: 66.83

Gene sequence:

>1203_bases
ATGTCCGAACAACCCTTGCCGACGCTGCCGATGTGGCGCGTCGATCACATCGAGCCCTCGCCTGAGATGTTGGCGCTACG
CGCCAACGGTCCGATCCACCACGTACGCTTCCCGTCCGGGCACGAAGGCTGGTGGGTGACAGGCTACGACGAGGCCAAGG
CGGCGCTGTCCGACGCGGCGTTCCGGCCCGCGGGAATGCCGCCGGCGGCATTCACCCCGGATTCGGTGATTCTCGGTTCG
CCGGGGTGGCTTGTCTCGCACGAGGGGGGCGAGCATGCCCGGTTACGCACGATCGTGGCGCCGGCCTTCAGCAACCGCAG
GGTGAAGGTGCTCGCGCAGCAGGTCGAGGCGATCGCCGCGCAGTTGTTCGAGACGCTGGCGGCCCAGCCCCAGCCCGCCG
ACCTGAGGCGCCACCTCTCCTTTCCGCTGCCGGCCATGGTCATCAGCGCGCTGATGGGCGTGCTCTACGAGGATCACGCC
TTTTTCGCCGGGCTGTCCGACGAAGTGATGACGCACCAGCATGAAAGCGGCCCGCGCAGCGCGTCGCGCCTGGCCTGGGA
AGAACTGCGCGCCTACATTCGCGGCAAGATGTGGGACAAGCGCCAGGATCCGGGCGACAACCTGCTGACGGATCTGCTCG
CGGCGGTCGAGCAGGGCAATGCGACCGAGGAAGAGGCGATCGGCCTGGCGGCGGGAATGCTGGTGGCGGGGCACGAGAGC
ACCGTCGCGCAGATCGAATTCGGCCTGCTGGCCATGTTCCGCCATCCGCAACAGCGCGAACGCCTAGTCGGCGATCCATC
CCTGGTGGACAAGGCGGTGGAGGAAATCCTGCGCATGTACCCGCCGGGCGCGGGCTGGGACGGCATCATGCGCTATCCGA
GGACCGACGTGACTATCGCGGGCGTGCATATTCCCGCGGAGAGCAAGGTGCTGGTCGGCCTGCCGGCGACGTCGTTCGAT
CCGCGCCATTTCGACGACCCGGAAATCTTCGACATCGGACGCGACGAAAATCCGCACCTGACGTTTTCGCACGGGCCGCA
CTACTGCATCGGCATGGCGCTGGCCAGGCTGGAACTCAAGGTGGTGGTCGGCTCGATCTTCCAGCGCTTTCCCGCGCTGC
GCCTGGCCGTGGCGCCCGAAGAACTGAAGTTGCGCAAGGAGATCATCACTGGCGGGTTCGAGGAGTTCCCGGTGCTCTGG
TGA

Upstream 100 bases:

>100_bases
GAGTCGGGCTACCCCCCGGACGACGTCTACGTGCCGTCGTAATCATTCGCTGCCCGCAGCGCCTTCCGCCCTTCCATCGC
TTAGAGAGTGAAGTGCCACC

Downstream 100 bases:

>100_bases
CGCGCGGACGCCGCCCGGAATCGCGATCTACTCCGCAATTTGCCGGCGCGCCCAGCGCGCGCCGGTCAGATCAGCCAGCC
AACAGGTAACCAAGATGGAC

Product: cytochrome P-450

Products: NA

Alternate protein names: Cytochrome P450 112 [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSEQPLPTLPMWRVDHIEPSPEMLALRANGPIHHVRFPSGHEGWWVTGYDEAKAALSDAAFRPAGMPPAAFTPDSVILGS
PGWLVSHEGGEHARLRTIVAPAFSNRRVKVLAQQVEAIAAQLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHA
FFAGLSDEVMTHQHESGPRSASRLAWEELRAYIRGKMWDKRQDPGDNLLTDLLAAVEQGNATEEEAIGLAAGMLVAGHES
TVAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIAGVHIPAESKVLVGLPATSFD
PRHFDDPEIFDIGRDENPHLTFSHGPHYCIGMALARLELKVVVGSIFQRFPALRLAVAPEELKLRKEIITGGFEEFPVLW

Sequences:

>Translated_400_residues
MSEQPLPTLPMWRVDHIEPSPEMLALRANGPIHHVRFPSGHEGWWVTGYDEAKAALSDAAFRPAGMPPAAFTPDSVILGS
PGWLVSHEGGEHARLRTIVAPAFSNRRVKVLAQQVEAIAAQLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHA
FFAGLSDEVMTHQHESGPRSASRLAWEELRAYIRGKMWDKRQDPGDNLLTDLLAAVEQGNATEEEAIGLAAGMLVAGHES
TVAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIAGVHIPAESKVLVGLPATSFD
PRHFDDPEIFDIGRDENPHLTFSHGPHYCIGMALARLELKVVVGSIFQRFPALRLAVAPEELKLRKEIITGGFEEFPVLW
>Mature_399_residues
SEQPLPTLPMWRVDHIEPSPEMLALRANGPIHHVRFPSGHEGWWVTGYDEAKAALSDAAFRPAGMPPAAFTPDSVILGSP
GWLVSHEGGEHARLRTIVAPAFSNRRVKVLAQQVEAIAAQLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHAF
FAGLSDEVMTHQHESGPRSASRLAWEELRAYIRGKMWDKRQDPGDNLLTDLLAAVEQGNATEEEAIGLAAGMLVAGHEST
VAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIAGVHIPAESKVLVGLPATSFDP
RHFDDPEIFDIGRDENPHLTFSHGPHYCIGMALARLELKVVVGSIFQRFPALRLAVAPEELKLRKEIITGGFEEFPVLW

Specific function: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics [H]

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Drosophila melanogaster, GI17933518, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 44183; Mature: 44052

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQPLPTLPMWRVDHIEPSPEMLALRANGPIHHVRFPSGHEGWWVTGYDEAKAALSDAA
CCCCCCCCCCCCEECCCCCCCCEEEEECCCCEEEEECCCCCCCEEEECHHHHHHHHHHHC
FRPAGMPPAAFTPDSVILGSPGWLVSHEGGEHARLRTIVAPAFSNRRVKVLAQQVEAIAA
CCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
QLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHAFFAGLSDEVMTHQHESGPRS
HHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCCCCH
ASRLAWEELRAYIRGKMWDKRQDPGDNLLTDLLAAVEQGNATEEEAIGLAAGMLVAGHES
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCC
TVAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIA
HHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEE
GVHIPAESKVLVGLPATSFDPRHFDDPEIFDIGRDENPHLTFSHGPHYCIGMALARLELK
EEEECCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEECCCCCHHHHHHHHHHHHH
VVVGSIFQRFPALRLAVAPEELKLRKEIITGGFEEFPVLW
HHHHHHHHHCCHHEEEECHHHHHHHHHHHHCCHHHCCCCC
>Mature Secondary Structure 
SEQPLPTLPMWRVDHIEPSPEMLALRANGPIHHVRFPSGHEGWWVTGYDEAKAALSDAA
CCCCCCCCCCCEECCCCCCCCEEEEECCCCEEEEECCCCCCCEEEECHHHHHHHHHHHC
FRPAGMPPAAFTPDSVILGSPGWLVSHEGGEHARLRTIVAPAFSNRRVKVLAQQVEAIAA
CCCCCCCCCCCCCCCEEECCCCEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
QLFETLAAQPQPADLRRHLSFPLPAMVISALMGVLYEDHAFFAGLSDEVMTHQHESGPRS
HHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHCCHHCCCCCHHHHHHCCCCCCCH
ASRLAWEELRAYIRGKMWDKRQDPGDNLLTDLLAAVEQGNATEEEAIGLAAGMLVAGHES
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEECCCC
TVAQIEFGLLAMFRHPQQRERLVGDPSLVDKAVEEILRMYPPGAGWDGIMRYPRTDVTIA
HHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCEEEE
GVHIPAESKVLVGLPATSFDPRHFDDPEIFDIGRDENPHLTFSHGPHYCIGMALARLELK
EEEECCCCEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEECCCCCHHHHHHHHHHHHH
VVVGSIFQRFPALRLAVAPEELKLRKEIITGGFEEFPVLW
HHHHHHHHHCCHHEEEECHHHHHHHHHHHHCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9655913; 12597275 [H]