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The map label for this gene is dapA [H]

Identifier: 13475264

GI number: 13475264

Start: 5110244

End: 5111152

Strand: Direct

Name: dapA [H]

Synonym: mlr6292

Alternate gene names: 13475264

Gene position: 5110244-5111152 (Clockwise)

Preceding gene: 13475262

Following gene: 13475265

Centisome position: 72.63

GC content: 58.53

Gene sequence:

>909_bases
ATGGCAAAGTGGGCTGGTGTATTCCCCGCAGTGACGACGAAGCTGACGAGGGATGGCAAGGTTGACCTTCGGGCGACCAA
GGACAGCCTTGACCGCCTCGTCAAGGCAGGTGTTTCCGGCGTCATTGTGCTTCCCATGCTAGGCGAGAACGCTTCGATGT
CGCTGAAGGATCGTGAAGACATCATCGGAGGTGCTGTCGAAGTCGTAGCTGGTCGTGTTCCGGTTCTCTCCGGCCTCGCC
GAAATCACACTCGACAATGCGAAGGCAAACGCCAAGCTCTACGAATCGTTCGGCGCCCAGGGGCTCATGGTATTCCCAAG
CCTTGGCTACAAGACCGACGATCGCGAAACGGTCGAGTGGTACAAGGGGGTCGCCAGCGCTTCCTCGCTTCCGATCATGA
TCTACAACAACCCGATCGCCTACGGCGTCGACTGCACGGTCAATGTTCTCAAGCAACTTGTCGACACCCCGGAAATCGTC
TGCGTTAAGGAAGAAACTGGCGACATTCGTCGCGTCACCGACATGTTTGTCGAGCTCGGCGACCGCTTCAGCATCTTCTG
CGGCGTCGACGATCTGATTGTGGAAAGTTGCGCGCTGGGTGTTACCGGCTGGGTCTCGGGCATGACCAACGTTTGGCCGT
CAGAATGCGTCGAGCTCTTCAACCTCTGCATCCAAAACAGGTACGAGGAGGCGCGCGCGCTTTACCACATCCTGACGCCG
TCCTTCCATCTCGACACCCACGTGAAGCTGGTTCAGTACATCAAGCTCGCCGAGAGCCTGGTCTACGGCGCACCGGAATG
GACCCGTGCCCCGCGCTTGCCACTCGTCGGCGAAGAGCGTGACTTTGTCACATCGACGATTCAGCTAGCAATCGAGACCT
TGGCCAAGCGGGTGAAGAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
TCGTCGAGAGTATCCCAAAAAAGGGTGACATCAAAGGGTAGACATGTTGTTTGATGCCATGTAGATTGGATCCAGTTGGA
TCGCTTATGGATGGAGAACC

Downstream 100 bases:

>100_bases
TTTGGATCGTAGGAAAATCGGGGCGTCGCAATGATCCGATCGCGACGTCCGCTCGAAGGGTGGCTCGTTCGGAAGACGGC
AACTGAAGTTCAAAGGTCAA

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MAKWAGVFPAVTTKLTRDGKVDLRATKDSLDRLVKAGVSGVIVLPMLGENASMSLKDREDIIGGAVEVVAGRVPVLSGLA
EITLDNAKANAKLYESFGAQGLMVFPSLGYKTDDRETVEWYKGVASASSLPIMIYNNPIAYGVDCTVNVLKQLVDTPEIV
CVKEETGDIRRVTDMFVELGDRFSIFCGVDDLIVESCALGVTGWVSGMTNVWPSECVELFNLCIQNRYEEARALYHILTP
SFHLDTHVKLVQYIKLAESLVYGAPEWTRAPRLPLVGEERDFVTSTIQLAIETLAKRVKKAA

Sequences:

>Translated_302_residues
MAKWAGVFPAVTTKLTRDGKVDLRATKDSLDRLVKAGVSGVIVLPMLGENASMSLKDREDIIGGAVEVVAGRVPVLSGLA
EITLDNAKANAKLYESFGAQGLMVFPSLGYKTDDRETVEWYKGVASASSLPIMIYNNPIAYGVDCTVNVLKQLVDTPEIV
CVKEETGDIRRVTDMFVELGDRFSIFCGVDDLIVESCALGVTGWVSGMTNVWPSECVELFNLCIQNRYEEARALYHILTP
SFHLDTHVKLVQYIKLAESLVYGAPEWTRAPRLPLVGEERDFVTSTIQLAIETLAKRVKKAA
>Mature_301_residues
AKWAGVFPAVTTKLTRDGKVDLRATKDSLDRLVKAGVSGVIVLPMLGENASMSLKDREDIIGGAVEVVAGRVPVLSGLAE
ITLDNAKANAKLYESFGAQGLMVFPSLGYKTDDRETVEWYKGVASASSLPIMIYNNPIAYGVDCTVNVLKQLVDTPEIVC
VKEETGDIRRVTDMFVELGDRFSIFCGVDDLIVESCALGVTGWVSGMTNVWPSECVELFNLCIQNRYEEARALYHILTPS
FHLDTHVKLVQYIKLAESLVYGAPEWTRAPRLPLVGEERDFVTSTIQLAIETLAKRVKKAA

Specific function: Unknown

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=275, Percent_Identity=24.7272727272727, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI87082415, Length=224, Percent_Identity=29.9107142857143, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1786463, Length=223, Percent_Identity=29.1479820627803, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788823, Length=243, Percent_Identity=26.7489711934156, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789620, Length=211, Percent_Identity=23.696682464455, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 33122; Mature: 32990

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKWAGVFPAVTTKLTRDGKVDLRATKDSLDRLVKAGVSGVIVLPMLGENASMSLKDRED
CCCCCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHH
IIGGAVEVVAGRVPVLSGLAEITLDNAKANAKLYESFGAQGLMVFPSLGYKTDDRETVEW
HHHHHHHHHHCCCHHHHHHHHHEECCCCCCHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
YKGVASASSLPIMIYNNPIAYGVDCTVNVLKQLVDTPEIVCVKEETGDIRRVTDMFVELG
HHHHCCCCCCCEEEECCCEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHC
DRFSIFCGVDDLIVESCALGVTGWVSGMTNVWPSECVELFNLCIQNRYEEARALYHILTP
CCEEEEECHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFHLDTHVKLVQYIKLAESLVYGAPEWTRAPRLPLVGEERDFVTSTIQLAIETLAKRVKK
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AA
CC
>Mature Secondary Structure 
AKWAGVFPAVTTKLTRDGKVDLRATKDSLDRLVKAGVSGVIVLPMLGENASMSLKDRED
CCCCCCCHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHH
IIGGAVEVVAGRVPVLSGLAEITLDNAKANAKLYESFGAQGLMVFPSLGYKTDDRETVEW
HHHHHHHHHHCCCHHHHHHHHHEECCCCCCHHHHHHHCCCCEEEECCCCCCCCCHHHHHH
YKGVASASSLPIMIYNNPIAYGVDCTVNVLKQLVDTPEIVCVKEETGDIRRVTDMFVELG
HHHHCCCCCCCEEEECCCEEECCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHC
DRFSIFCGVDDLIVESCALGVTGWVSGMTNVWPSECVELFNLCIQNRYEEARALYHILTP
CCEEEEECHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SFHLDTHVKLVQYIKLAESLVYGAPEWTRAPRLPLVGEERDFVTSTIQLAIETLAKRVKK
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]