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The map label for this gene is ltaE [H]

Identifier: 13475120

GI number: 13475120

Start: 4961620

End: 4962711

Strand: Direct

Name: ltaE [H]

Synonym: mlr6130

Alternate gene names: 13475120

Gene position: 4961620-4962711 (Clockwise)

Preceding gene: 13475119

Following gene: 13475121

Centisome position: 70.52

GC content: 65.02

Gene sequence:

>1092_bases
ATGAACGAAAGCAAGCAGACCCGCCCCCGCGGCTTTACCAGCGACAACATCGCCGGCGTCTCCCCCGAGGTGATCGCAGC
CATCACCGCGTGCGCGTCAGGTCAGGCGCTTCCCTACGGCAACGATGAGCTGACGCATACCGTCGAGCACCAGCTCGCCG
AGGTGTTCGAGCATGCGGTCGACGTGTTCCTCGTTTCGACGGGGTCGGCGGCGAACGCGCTGGCGCTCGCGGCGATTACG
CCGCCATGGGGCAGCATCCTCTCGCACGCCGACGCACACATCAACCGCGACGAGTGCGGCGCGCCGGAGTTCTACACCGC
CGGTGCGAAGTTGGTGCAGCTTCCAGGCGAGGCTGGCAAAATCGACATCGACGCCTTGGCGGCCAATGCCATGCGCATGG
TGGGCGATATCCACTCGGTCCAGCCCTCCAGCGTCAGCATCACGCAGGCGACCGAGATGGGATCGGTCTACGCGCTCGAC
GAGATCAAGGCCATCAGCCATATCTGCCGGTCAGCGAACCTGCCGCTCCACATGGACGGTGCTCGCTTCGCCAACGCCCT
CGTCACTCTGCGCTGCTCGCCGGCCGAGATGACGTGGAAGGCCGGCGTCGACCTTGTGTCATTTGGCGCCACGAAGAATG
GAACGTTTGGGGTCGATGCGGTCGTCTCGTTCCGCGGAGATCTCGCGAGCACGATCGCCTTTCGCCAAAAGCGGGCCGGC
CAGTTGAGTTCCAAGATGCGCTTCATGGCGGCGCAAATGGACGGTTATCTGAGGGACGGTGTCTGGCTTCGCAACGCGGT
CCATGCCAATGCGATGGCATCGGCGCTCGCGCGGGGGTTGGCCCTGGTGCCAGGCGTGAAGATCCAGCAGCGTCCCGAGG
CCAACATCCTGTTCTGCCGACTTCCCACGTCCCTGATCCGGGGGCTGCTCGACATGGGATTCCGCTTCTACCATGATCGC
TGGGAGCCCGGGATCGTGAGGTTCGTCACCTCTTTCGCGACGACCGAGGCCGACGTGTCCGACTTGATCGGCGCGGCAAC
CAGCCTCTGCGCACCGGTCGGCTCGGCTCGTGTTCCGGCTGGCGCCGAATGA

Upstream 100 bases:

>100_bases
GTGACGCCGGCGCGTTACCTCTCGGTTTGAATATCGTTCAATAAAGCGCGCGGCGAACCGTCTAGCTTGGACGCTCAATG
GATGAAAAGAGCGTCAGACC

Downstream 100 bases:

>100_bases
GTGTGGCGACCGTCGAGCGCTCTCGCCGCCCGTCACGGATGTCCTCTTTGCTCGACTGCATTGATGATCCGAGCGTTCTG
GCCGCACGGGCATCTCAGGC

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNESKQTRPRGFTSDNIAGVSPEVIAAITACASGQALPYGNDELTHTVEHQLAEVFEHAVDVFLVSTGSAANALALAAIT
PPWGSILSHADAHINRDECGAPEFYTAGAKLVQLPGEAGKIDIDALAANAMRMVGDIHSVQPSSVSITQATEMGSVYALD
EIKAISHICRSANLPLHMDGARFANALVTLRCSPAEMTWKAGVDLVSFGATKNGTFGVDAVVSFRGDLASTIAFRQKRAG
QLSSKMRFMAAQMDGYLRDGVWLRNAVHANAMASALARGLALVPGVKIQQRPEANILFCRLPTSLIRGLLDMGFRFYHDR
WEPGIVRFVTSFATTEADVSDLIGAATSLCAPVGSARVPAGAE

Sequences:

>Translated_363_residues
MNESKQTRPRGFTSDNIAGVSPEVIAAITACASGQALPYGNDELTHTVEHQLAEVFEHAVDVFLVSTGSAANALALAAIT
PPWGSILSHADAHINRDECGAPEFYTAGAKLVQLPGEAGKIDIDALAANAMRMVGDIHSVQPSSVSITQATEMGSVYALD
EIKAISHICRSANLPLHMDGARFANALVTLRCSPAEMTWKAGVDLVSFGATKNGTFGVDAVVSFRGDLASTIAFRQKRAG
QLSSKMRFMAAQMDGYLRDGVWLRNAVHANAMASALARGLALVPGVKIQQRPEANILFCRLPTSLIRGLLDMGFRFYHDR
WEPGIVRFVTSFATTEADVSDLIGAATSLCAPVGSARVPAGAE
>Mature_363_residues
MNESKQTRPRGFTSDNIAGVSPEVIAAITACASGQALPYGNDELTHTVEHQLAEVFEHAVDVFLVSTGSAANALALAAIT
PPWGSILSHADAHINRDECGAPEFYTAGAKLVQLPGEAGKIDIDALAANAMRMVGDIHSVQPSSVSITQATEMGSVYALD
EIKAISHICRSANLPLHMDGARFANALVTLRCSPAEMTWKAGVDLVSFGATKNGTFGVDAVVSFRGDLASTIAFRQKRAG
QLSSKMRFMAAQMDGYLRDGVWLRNAVHANAMASALARGLALVPGVKIQQRPEANILFCRLPTSLIRGLLDMGFRFYHDR
WEPGIVRFVTSFATTEADVSDLIGAATSLCAPVGSARVPAGAE

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38468; Mature: 38468

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNESKQTRPRGFTSDNIAGVSPEVIAAITACASGQALPYGNDELTHTVEHQLAEVFEHAV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DVFLVSTGSAANALALAAITPPWGSILSHADAHINRDECGAPEFYTAGAKLVQLPGEAGK
HEEEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCCC
IDIDALAANAMRMVGDIHSVQPSSVSITQATEMGSVYALDEIKAISHICRSANLPLHMDG
EEHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCEEECH
ARFANALVTLRCSPAEMTWKAGVDLVSFGATKNGTFGVDAVVSFRGDLASTIAFRQKRAG
HHHHCEEEEEEECCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLSSKMRFMAAQMDGYLRDGVWLRNAVHANAMASALARGLALVPGVKIQQRPEANILFCR
HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
LPTSLIRGLLDMGFRFYHDRWEPGIVRFVTSFATTEADVSDLIGAATSLCAPVGSARVPA
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
GAE
CCC
>Mature Secondary Structure
MNESKQTRPRGFTSDNIAGVSPEVIAAITACASGQALPYGNDELTHTVEHQLAEVFEHAV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
DVFLVSTGSAANALALAAITPPWGSILSHADAHINRDECGAPEFYTAGAKLVQLPGEAGK
HEEEEECCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCCCCCEECCCCEEEECCCCCCC
IDIDALAANAMRMVGDIHSVQPSSVSITQATEMGSVYALDEIKAISHICRSANLPLHMDG
EEHHHHHHHHHHHHHHHHCCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCEEECH
ARFANALVTLRCSPAEMTWKAGVDLVSFGATKNGTFGVDAVVSFRGDLASTIAFRQKRAG
HHHHCEEEEEEECCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLSSKMRFMAAQMDGYLRDGVWLRNAVHANAMASALARGLALVPGVKIQQRPEANILFCR
HHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEE
LPTSLIRGLLDMGFRFYHDRWEPGIVRFVTSFATTEADVSDLIGAATSLCAPVGSARVPA
CCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
GAE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]