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The map label for this gene is queC2

Identifier: 13474943

GI number: 13474943

Start: 4803422

End: 4804159

Strand: Reverse

Name: queC2

Synonym: mll5936

Alternate gene names: 13474943

Gene position: 4804159-4803422 (Counterclockwise)

Preceding gene: 13474944

Following gene: 13474933

Centisome position: 68.28

GC content: 60.43

Gene sequence:

>738_bases
ATGCAACGAGATCCGGGAACCGCACTCGTCCTTTTCTCCGGCGGCCAGGATTCGACAACCTGCCTGGCTTGGGCGCTCGA
GAACTTCGAGCGCGTCGAGACAATCGGCTTCGACTATGGGCAGCGGCATCGGATCGAGCTCGATGTGCGGCCTTACCTGC
TCGAGCGCATTCGAACAGACTTTCCGGCCTGGCGCGGGCGACTAGGCGGGGACCACATGATTGACATGGCCGTGCTCGGC
CAAATCAGTGATACCGCGCTCACGCGCGGCGTCGAGGTCGCACTGAACGCGAACGGTCTACCAAATACCTTCGTGCCTGG
CCGCAACCTTCTGTTCCTCGGCTTTGCGGCCGCGTTAGCTTACCGGCTGAGCGCGAAACACCTCGTAATCGGCGTGGCCG
AGACGGATCGTTTCAGCTACCCAGATTGTCGAGATGACGCGGTTAAGGCGATTCAACTTGCCCTGAACCTTGGAATGGAG
AAGCGGTTCATCATTCACACACCCCTCATGCACCGTGACAAGGCGCAGACCTGGGCGCTGGCGGATTGGCTGGGCGGAGA
GGCGCTGGTGAAGCTCATCTGCGAGGGAAGCCACACCTGCTATAGCGGAGACCGCGAGCATAGACACAGCTGGGGTTTCG
GTTGCGGGACCTGCATCGAGTGTAATCTTCGGGCAGCGGGATGGGAGCAATTCCGATCCTGCAAAGAGGCACCCGTGACC
GCCCATGAAATGACGTAA

Upstream 100 bases:

>100_bases
GTCTGGATCTGGAACCAAACCAAGCCGCTTCTTGGCCAAATGTGCTCGGTAACAGTCTATGAGACACCGCTGTGCTGGGC
TGAATACGAGGGTTGACCCG

Downstream 100 bases:

>100_bases
GCGCCAAGATCCAGGCCGGCGGTGGCAATCTGTTCCATAGATCGTTTCCTTCTCTTTGTGATCAGCACGACGAGGGTAGG
CGTCTTCGATGCCGTTTCGA

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase 2; PreQ(0) synthase 2; Queuosine biosynthesis protein queC 2

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MQRDPGTALVLFSGGQDSTTCLAWALENFERVETIGFDYGQRHRIELDVRPYLLERIRTDFPAWRGRLGGDHMIDMAVLG
QISDTALTRGVEVALNANGLPNTFVPGRNLLFLGFAAALAYRLSAKHLVIGVAETDRFSYPDCRDDAVKAIQLALNLGME
KRFIIHTPLMHRDKAQTWALADWLGGEALVKLICEGSHTCYSGDREHRHSWGFGCGTCIECNLRAAGWEQFRSCKEAPVT
AHEMT

Sequences:

>Translated_245_residues
MQRDPGTALVLFSGGQDSTTCLAWALENFERVETIGFDYGQRHRIELDVRPYLLERIRTDFPAWRGRLGGDHMIDMAVLG
QISDTALTRGVEVALNANGLPNTFVPGRNLLFLGFAAALAYRLSAKHLVIGVAETDRFSYPDCRDDAVKAIQLALNLGME
KRFIIHTPLMHRDKAQTWALADWLGGEALVKLICEGSHTCYSGDREHRHSWGFGCGTCIECNLRAAGWEQFRSCKEAPVT
AHEMT
>Mature_245_residues
MQRDPGTALVLFSGGQDSTTCLAWALENFERVETIGFDYGQRHRIELDVRPYLLERIRTDFPAWRGRLGGDHMIDMAVLG
QISDTALTRGVEVALNANGLPNTFVPGRNLLFLGFAAALAYRLSAKHLVIGVAETDRFSYPDCRDDAVKAIQLALNLGME
KRFIIHTPLMHRDKAQTWALADWLGGEALVKLICEGSHTCYSGDREHRHSWGFGCGTCIECNLRAAGWEQFRSCKEAPVT
AHEMT

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=238, Percent_Identity=44.1176470588235, Blast_Score=186, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC2_RHILO (Q98AM3)

Other databases:

- EMBL:   AL672114
- EMBL:   BA000012
- RefSeq:   NP_106513.1
- ProteinModelPortal:   Q98AM3
- SMR:   Q98AM3
- GeneID:   1229170
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5936
- NMPDR:   fig|266835.1.peg.4615
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK864419
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 27324; Mature: 27324

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRDPGTALVLFSGGQDSTTCLAWALENFERVETIGFDYGQRHRIELDVRPYLLERIRTD
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHC
FPAWRGRLGGDHMIDMAVLGQISDTALTRGVEVALNANGLPNTFVPGRNLLFLGFAAALA
CHHHHCCCCCCCEEHHHHHCCCHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
YRLSAKHLVIGVAETDRFSYPDCRDDAVKAIQLALNLGMEKRFIIHTPLMHRDKAQTWAL
HHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHH
ADWLGGEALVKLICEGSHTCYSGDREHRHSWGFGCGTCIECNLRAAGWEQFRSCKEAPVT
HHHHCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCC
AHEMT
CCCCC
>Mature Secondary Structure
MQRDPGTALVLFSGGQDSTTCLAWALENFERVETIGFDYGQRHRIELDVRPYLLERIRTD
CCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHC
FPAWRGRLGGDHMIDMAVLGQISDTALTRGVEVALNANGLPNTFVPGRNLLFLGFAAALA
CHHHHCCCCCCCEEHHHHHCCCHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHH
YRLSAKHLVIGVAETDRFSYPDCRDDAVKAIQLALNLGMEKRFIIHTPLMHRDKAQTWAL
HHHCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHH
ADWLGGEALVKLICEGSHTCYSGDREHRHSWGFGCGTCIECNLRAAGWEQFRSCKEAPVT
HHHHCHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCEEEECCCCCCHHHHHHHHCCCCC
AHEMT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12003951; 11214968