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The map label for this gene is adc1

Identifier: 13474930

GI number: 13474930

Start: 4785119

End: 4785862

Strand: Reverse

Name: adc1

Synonym: mll5917

Alternate gene names: 13474930

Gene position: 4785862-4785119 (Counterclockwise)

Preceding gene: 13474931

Following gene: 13474929

Centisome position: 68.02

GC content: 62.37

Gene sequence:

>744_bases
ATGCACCAAGATACCGTCCGTGGGAAAGCTTTCGCCATGCCCCTGATCAGCCCGGCCTACCCGGCCGGCCCATATCGCTT
CCGCAACCGGGAGTATCTGATCATCACATATCGCACCGATCCGCAGAAACTGCGCGACCTTGTGCCGGAGCCGCTTCAGG
TGTGCGAGCCTATGGTCAAGTTCGAGTTCATTCGCATGCCGGACTCGACGGGCTTCGGCGACTACACGGAAGGCGGACAG
GTCATCCCTGTCTCCTTCTATGGCCGCAGGGGGAGCTATACCCACTGCATGTTTCTCGACGACCATCCGCCGATAGCGGG
CGGACGCGAGTTGTGGGGCTTTCCCAAGAAGCTCGCTAGCCCAACGCTCCGAACGGAGACGGATACCCTTGTTGGCACGC
TGGACTACGGGCCGGTCCGCGTCGCGACGGGTACCATGGGCTACAAGCACCGAGCCGCCGACCTCGCGAGCGTGAGGGCC
TCGCTCGCTGAACCGAATTTCCTCCTCAAAATTATCCCGCATGTCGACGGCACGCCGCGCATCTGTGAGCTCGTGGAATA
TCATCTAGAGGACGTCCATTTGAGGGGCGCCTGGACCGGCCCGGCAGCCCTGAACCTCTGGTCGCATGCGCTTGCCCCCG
TCGCCGAACTGCCGGTGCTGGAAGTAGTCTCGGCAGTACACCTCGTCGCAGATCTCACGCTCGCGCTCGGGAAGGTCGTC
CACGACTATCTCGCGAAAGCCTAG

Upstream 100 bases:

>100_bases
TGCATCCCTTACGAGGCTGCGACAGCACTTCGGAGAGCCTCGCCGCCATCATGCAGACCGATCTAAGCCCCACCTGATCC
AGCACAAAGGAATTTCGAAC

Downstream 100 bases:

>100_bases
CCTCGCCATCGGAAAGGAAGAAACCATGAACTTTTACAGTGATATCTCATTGAACCAACGCGATGGGGAGCCGGTGGCCG
GCTTCTCGACAAGGTGGCGC

Product: acetoacetate decarboxylase

Products: NA

Alternate protein names: AAD 1; ADC 1

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MHQDTVRGKAFAMPLISPAYPAGPYRFRNREYLIITYRTDPQKLRDLVPEPLQVCEPMVKFEFIRMPDSTGFGDYTEGGQ
VIPVSFYGRRGSYTHCMFLDDHPPIAGGRELWGFPKKLASPTLRTETDTLVGTLDYGPVRVATGTMGYKHRAADLASVRA
SLAEPNFLLKIIPHVDGTPRICELVEYHLEDVHLRGAWTGPAALNLWSHALAPVAELPVLEVVSAVHLVADLTLALGKVV
HDYLAKA

Sequences:

>Translated_247_residues
MHQDTVRGKAFAMPLISPAYPAGPYRFRNREYLIITYRTDPQKLRDLVPEPLQVCEPMVKFEFIRMPDSTGFGDYTEGGQ
VIPVSFYGRRGSYTHCMFLDDHPPIAGGRELWGFPKKLASPTLRTETDTLVGTLDYGPVRVATGTMGYKHRAADLASVRA
SLAEPNFLLKIIPHVDGTPRICELVEYHLEDVHLRGAWTGPAALNLWSHALAPVAELPVLEVVSAVHLVADLTLALGKVV
HDYLAKA
>Mature_247_residues
MHQDTVRGKAFAMPLISPAYPAGPYRFRNREYLIITYRTDPQKLRDLVPEPLQVCEPMVKFEFIRMPDSTGFGDYTEGGQ
VIPVSFYGRRGSYTHCMFLDDHPPIAGGRELWGFPKKLASPTLRTETDTLVGTLDYGPVRVATGTMGYKHRAADLASVRA
SLAEPNFLLKIIPHVDGTPRICELVEYHLEDVHLRGAWTGPAALNLWSHALAPVAELPVLEVVSAVHLVADLTLALGKVV
HDYLAKA

Specific function: Catalyzes the conversion of acetoacetate to acetone and carbon dioxide

COG id: COG4689

COG function: function code Q; Acetoacetate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADC1_RHILO (Q98AN6)

Other databases:

- EMBL:   AL672114
- EMBL:   BA000012
- RefSeq:   NP_106500.1
- ProteinModelPortal:   Q98AN6
- SMR:   Q98AN6
- GeneID:   1229159
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mll5917
- NMPDR:   fig|266835.1.peg.4603
- HOGENOM:   HBG294597
- OMA:   GTHILAD
- ProtClustDB:   PRK02265
- BRENDA:   4.1.1.4
- HAMAP:   MF_00597
- InterPro:   IPR010451

Pfam domain/function: PF06314 ADC

EC number: =4.1.1.4

Molecular weight: Translated: 27390; Mature: 27390

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: ACT_SITE 116-116

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQDTVRGKAFAMPLISPAYPAGPYRFRNREYLIITYRTDPQKLRDLVPEPLQVCEPMVK
CCCCCCCCCEEECCCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHCCCCHHHHHCHHHH
FEFIRMPDSTGFGDYTEGGQVIPVSFYGRRGSYTHCMFLDDHPPIAGGRELWGFPKKLAS
EEEEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHCCCCHHHCC
PTLRTETDTLVGTLDYGPVRVATGTMGYKHRAADLASVRASLAEPNFLLKIIPHVDGTPR
CCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
ICELVEYHLEDVHLRGAWTGPAALNLWSHALAPVAELPVLEVVSAVHLVADLTLALGKVV
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HDYLAKA
HHHHHCC
>Mature Secondary Structure
MHQDTVRGKAFAMPLISPAYPAGPYRFRNREYLIITYRTDPQKLRDLVPEPLQVCEPMVK
CCCCCCCCCEEECCCCCCCCCCCCEEECCCEEEEEEECCCHHHHHHCCCCHHHHHCHHHH
FEFIRMPDSTGFGDYTEGGQVIPVSFYGRRGSYTHCMFLDDHPPIAGGRELWGFPKKLAS
EEEEECCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCCHHHCCCCHHHCC
PTLRTETDTLVGTLDYGPVRVATGTMGYKHRAADLASVRASLAEPNFLLKIIPHVDGTPR
CCCCCCCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHH
ICELVEYHLEDVHLRGAWTGPAALNLWSHALAPVAELPVLEVVSAVHLVADLTLALGKVV
HHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HDYLAKA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12003951; 11214968