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The map label for this gene is 13474891

Identifier: 13474891

GI number: 13474891

Start: 4743584

End: 4744132

Strand: Reverse

Name: 13474891

Synonym: mll5873

Alternate gene names: NA

Gene position: 4744132-4743584 (Counterclockwise)

Preceding gene: 13474905

Following gene: 13474890

Centisome position: 67.43

GC content: 58.47

Gene sequence:

>549_bases
ATGACCGTCAAAAAAAAGGTTCCTTTCGTCACCTTTCGCACGCGTGTTCGCGATGACTCCATCGAGGGGCCAAACCCGTA
CCGCTGGGAAGACAAGACATCCGACGACTATTTCCGCGGCAAGCGCATCATCCTGTTCTCGCTGCCCGGTGCCTTCACCC
CGACCTGCTCGACCTTGCAGTTGCCCGATTTCGAAATGCTCTACGACGAGTTCGAGAAGGAGGGAATTGACGCGATCTAC
TGCGTTTCCGTCAACGATGCCTTCGTCATGAATGCCTGGGGCAAGGCCCTGGGGCTGCAGAAAGTCCAGCTCATCCCAGA
CGGCTCGGGCGAGTTCACCCGCAAGATGGGCATGCTGGTTGCCAAGGACAATCTCGGCTTCGGCATGCGCTCCTGGCGCT
ACGCTGCCGTGATCAACAATGGCGTAGTGGAGCAGTGGTTCGAGGAGGACGGTTTCTGCGACAACTGCGAGGCCGATCCC
TATGGCGTATCGTCGCCGCAGAACGTCCTTGAAACGTTGAGAGCCGCCAAAGCCGTGACGGCTGCATGA

Upstream 100 bases:

>100_bases
ACAAAACGCGCGGCGCCCGGCCGAATTGCCGGCCGAGGTCGATGCCGTGTCAGTTTCAACCGAAAAAGCAGCGCACCAGT
TTTCCTCCAGGAGCACATTG

Downstream 100 bases:

>100_bases
TCTAGACGAGTCAACGTCTCGAAAATCCCCTTGCACAAGGCGAAGGGTCGCTCGGTAGGAGTTTCACGCTAGCCATGGAG
TCCTCAGCAAGCCTGCTTCA

Product: peroxiredoxin 2 family protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 182; Mature: 181

Protein sequence:

>182_residues
MTVKKKVPFVTFRTRVRDDSIEGPNPYRWEDKTSDDYFRGKRIILFSLPGAFTPTCSTLQLPDFEMLYDEFEKEGIDAIY
CVSVNDAFVMNAWGKALGLQKVQLIPDGSGEFTRKMGMLVAKDNLGFGMRSWRYAAVINNGVVEQWFEEDGFCDNCEADP
YGVSSPQNVLETLRAAKAVTAA

Sequences:

>Translated_182_residues
MTVKKKVPFVTFRTRVRDDSIEGPNPYRWEDKTSDDYFRGKRIILFSLPGAFTPTCSTLQLPDFEMLYDEFEKEGIDAIY
CVSVNDAFVMNAWGKALGLQKVQLIPDGSGEFTRKMGMLVAKDNLGFGMRSWRYAAVINNGVVEQWFEEDGFCDNCEADP
YGVSSPQNVLETLRAAKAVTAA
>Mature_181_residues
TVKKKVPFVTFRTRVRDDSIEGPNPYRWEDKTSDDYFRGKRIILFSLPGAFTPTCSTLQLPDFEMLYDEFEKEGIDAIYC
VSVNDAFVMNAWGKALGLQKVQLIPDGSGEFTRKMGMLVAKDNLGFGMRSWRYAAVINNGVVEQWFEEDGFCDNCEADPY
GVSSPQNVLETLRAAKAVTAA

Specific function: Unknown

COG id: COG0678

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI6912238, Length=134, Percent_Identity=37.3134328358209, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323138, Length=130, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI78706776, Length=127, Percent_Identity=45.6692913385827, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI78709078, Length=127, Percent_Identity=45.6692913385827, Blast_Score=105, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20493; Mature: 20362

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVKKKVPFVTFRTRVRDDSIEGPNPYRWEDKTSDDYFRGKRIILFSLPGAFTPTCSTLQ
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCCCEEE
LPDFEMLYDEFEKEGIDAIYCVSVNDAFVMNAWGKALGLQKVQLIPDGSGEFTRKMGMLV
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHCCCEEEEEEECCCCHHHHHHCEEE
AKDNLGFGMRSWRYAAVINNGVVEQWFEEDGFCDNCEADPYGVSSPQNVLETLRAAKAVT
EECCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
AA
CC
>Mature Secondary Structure 
TVKKKVPFVTFRTRVRDDSIEGPNPYRWEDKTSDDYFRGKRIILFSLPGAFTPTCSTLQ
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCCCCEEE
LPDFEMLYDEFEKEGIDAIYCVSVNDAFVMNAWGKALGLQKVQLIPDGSGEFTRKMGMLV
CCCHHHHHHHHHHCCCCEEEEEECCCEEEEECHHHHCCCEEEEEEECCCCHHHHHHCEEE
AKDNLGFGMRSWRYAAVINNGVVEQWFEEDGFCDNCEADPYGVSSPQNVLETLRAAKAVT
EECCCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHC
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]