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The map label for this gene is nhoA [H]

Identifier: 13474840

GI number: 13474840

Start: 4690406

End: 4691218

Strand: Reverse

Name: nhoA [H]

Synonym: mll5814

Alternate gene names: 13474840

Gene position: 4691218-4690406 (Counterclockwise)

Preceding gene: 13474841

Following gene: 13474839

Centisome position: 66.67

GC content: 54.74

Gene sequence:

>813_bases
ATGGCATTCAATATTGCGATCTATCTGAATCGTATCGGCCTTGCTCGAGTGCCGACAACGGTCGACGGTCTTGTTGCCCT
TCAGCAGGCTCAAATGCGCGCGATTCCCTTTGAAAACATCGATGTGCTGTTGGGTGATATACCCAATCTGACTGAGAATT
CGATCTGGGCCAAACTGATCAATGCCCGGCGAGGGGGGTATTGCTTCGAATTGAACAAGTTGTTTGGCTTGGCGCTCGAA
GCACTCGGTTTCACGATCCAGCCCATCCTTTGCAGAGTGCGTATGGGTGCTGCGGAGGGTGGGCCACGCACACACCAGGC
ATTCATCTTAACCATCGAGGGCGTCGACTGGCTCGCCGACGCTGGCTTCGGTGGTCCAGCACCGATTGCACCGCTACGGA
TCGATACAGAGGAACTGCAAACAGCTGGCCGTGACGTGTTTCGCCTGCGAGCTGACTCCGCCAGCGGAGAACTCGTCGTT
GAACGCAAGAACGGGAATGAATGGTTCCCTCTTTATGGTTTCGATCGAGCCACCGCCTTGCCCTCAGATTTTGAGGGCGC
CAACTTCATCTGCGCTCGCTGGGACCGTTCGCCGTTTCCATCCAGCCTCATGATGAGCGTGCTGACAGCCGAAGGGCCTG
CGAACTTGTTCAACAAGGATTTCAGCTTGATTCGGAACCAAATTGAGGAAACAGAAACCCTCAAAACGAAGAGCGAACTG
CAGCGAGTCTTGTCCGATGTTTTTCGGCTGCACCTTCCTCGGTCCACGATTGATTCGTTGTGGGAAAAGCTTGGGTCGCG
TGGACGGGTATAG

Upstream 100 bases:

>100_bases
GGGGAGATGGCCACCTTACTCTGCTCCGTGAACCCTGGGACGTCATCGCGCTTTCGGCAGGCGTTCAACGAATACGAATC
CTAGGTGTTAAGGACATCCC

Downstream 100 bases:

>100_bases
GAAAGAAGGCCGTCAAGCCTTGCACTGCGGCGGTTTTCAGCAGTCGGATTTGCCCTTTTTGCAGGCACCGTGTGTGGCAT
CACTCGAAGCCCCATACGTA

Product: N-hydroxyarylamine O-acetyltransferase

Products: NA

Alternate protein names: Arylamine N-acetyltransferase; Arylhydroxamate N,O-acetyltransferase; NAT101 [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MAFNIAIYLNRIGLARVPTTVDGLVALQQAQMRAIPFENIDVLLGDIPNLTENSIWAKLINARRGGYCFELNKLFGLALE
ALGFTIQPILCRVRMGAAEGGPRTHQAFILTIEGVDWLADAGFGGPAPIAPLRIDTEELQTAGRDVFRLRADSASGELVV
ERKNGNEWFPLYGFDRATALPSDFEGANFICARWDRSPFPSSLMMSVLTAEGPANLFNKDFSLIRNQIEETETLKTKSEL
QRVLSDVFRLHLPRSTIDSLWEKLGSRGRV

Sequences:

>Translated_270_residues
MAFNIAIYLNRIGLARVPTTVDGLVALQQAQMRAIPFENIDVLLGDIPNLTENSIWAKLINARRGGYCFELNKLFGLALE
ALGFTIQPILCRVRMGAAEGGPRTHQAFILTIEGVDWLADAGFGGPAPIAPLRIDTEELQTAGRDVFRLRADSASGELVV
ERKNGNEWFPLYGFDRATALPSDFEGANFICARWDRSPFPSSLMMSVLTAEGPANLFNKDFSLIRNQIEETETLKTKSEL
QRVLSDVFRLHLPRSTIDSLWEKLGSRGRV
>Mature_269_residues
AFNIAIYLNRIGLARVPTTVDGLVALQQAQMRAIPFENIDVLLGDIPNLTENSIWAKLINARRGGYCFELNKLFGLALEA
LGFTIQPILCRVRMGAAEGGPRTHQAFILTIEGVDWLADAGFGGPAPIAPLRIDTEELQTAGRDVFRLRADSASGELVVE
RKNGNEWFPLYGFDRATALPSDFEGANFICARWDRSPFPSSLMMSVLTAEGPANLFNKDFSLIRNQIEETETLKTKSELQ
RVLSDVFRLHLPRSTIDSLWEKLGSRGRV

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649128, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI237649126, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI237649124, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI237649122, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI237649119, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI42741671, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI237649009, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI237649132, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI237649130, Length=279, Percent_Identity=27.2401433691756, Blast_Score=86, Evalue=5e-17,
Organism=Escherichia coli, GI1787736, Length=245, Percent_Identity=34.6938775510204, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: =2.3.1.118 [H]

Molecular weight: Translated: 29968; Mature: 29837

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFNIAIYLNRIGLARVPTTVDGLVALQQAQMRAIPFENIDVLLGDIPNLTENSIWAKLI
CEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH
NARRGGYCFELNKLFGLALEALGFTIQPILCRVRMGAAEGGPRTHQAFILTIEGVDWLAD
HCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHC
AGFGGPAPIAPLRIDTEELQTAGRDVFRLRADSASGELVVERKNGNEWFPLYGFDRATAL
CCCCCCCCCCCEEECHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEEECCCHHHCC
PSDFEGANFICARWDRSPFPSSLMMSVLTAEGPANLFNKDFSLIRNQIEETETLKTKSEL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRVLSDVFRLHLPRSTIDSLWEKLGSRGRV
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
AFNIAIYLNRIGLARVPTTVDGLVALQQAQMRAIPFENIDVLLGDIPNLTENSIWAKLI
EEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCHHHHHHHH
NARRGGYCFELNKLFGLALEALGFTIQPILCRVRMGAAEGGPRTHQAFILTIEGVDWLAD
HCCCCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCHHHHC
AGFGGPAPIAPLRIDTEELQTAGRDVFRLRADSASGELVVERKNGNEWFPLYGFDRATAL
CCCCCCCCCCCEEECHHHHHHCCCCEEEEECCCCCCCEEEEECCCCEEEEEECCCHHHCC
PSDFEGANFICARWDRSPFPSSLMMSVLTAEGPANLFNKDFSLIRNQIEETETLKTKSEL
CCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRVLSDVFRLHLPRSTIDSLWEKLGSRGRV
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1569093; 7889864; 11677609; 10876241 [H]