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The map label for this gene is resE [H]

Identifier: 13474696

GI number: 13474696

Start: 4532708

End: 4533973

Strand: Direct

Name: resE [H]

Synonym: mlr5642

Alternate gene names: 13474696

Gene position: 4532708-4533973 (Clockwise)

Preceding gene: 13474694

Following gene: 13474697

Centisome position: 64.42

GC content: 64.3

Gene sequence:

>1266_bases
ATGGCTGAGCAAAGCGCAGAGCAGGCAAGTGTGGCGCAAGCCATGGCCATCCGGCTGTGGAACAGCCGCTGGCTGCTCGT
CGCTGGCGTTATCGGTATCCTGATCGCTTTTGCCTTCGCGGGGATCTCCGCCTATGTTCTAGTGCCGGCGCTGCTTCTGC
TGCTCGCTGCCGCACTGTTGCCAACCACCGGCCTGCGCCAGTCCGGCGAGAATGCCGCCGCGATCGAGGCGATCGGCCTG
CAGCGCCTGTCGGGCGAATATCTGGCGGCGGCCGTCGCCGACCCGCTGATCATCTTCGACCGCTCCGCCACCATCGTCCA
CGCCAACGCCGCCGCCTTTGCCGCTTTCGGCGGCATCGCGCCGGGCCTGTCGCTGCCGCTGAAATTCCGGGCGCCGGAAA
TGCAGACCCTGCTCGACAGCGTGCTGTCGGGCACGATCGCTTCCGATGTCGTCGACTATACCGAGAAGCTGCCGGTCGAA
CGGGCCTACCGGGTCAGCGCGTCCTCGGTCGGGCACGGCACCGACCTCTATGTGCTGGTGTTCAAGGACCAGAGCGAAAC
GCGCAGGATCGACCGCATGCGCGCCGATTTCATCGCCAATGCCAGCCACGAATTGCGCACCCCGCTCGCCTCGATCGCCG
GTTTCATCGAAACGCTACGCGGACCGGCCCGCAACGATCCGGCGGCGCGCGAGCAATTCCTGCAGATCATGCAGAACCAG
ACCGGCCGCATGGCGCGTCTGATCGACGATCTGCTGTCCTTGTCCCGGCTGGAGATGAAGCCCTATCTGAAGCCCGGAAC
CGAGGTCGACCTGCGCCAGACCGTCGACAGCGTCATCGATTCACTGGCCCCGCTTGCCCACGAAAACAGCGTCGTCATCG
AGCGCGATTTCGCCAAGGGACCTCTCAACGTGCCGGGCGATCGTGACGAGCTGTTTCAGGTTTTCGAGAACCTGCTGGAA
AACGCCTGCAAATACGGTCAGTCCGGCGGCCGGGTCGTGGTGTCGATCGCGCACGCCGATGACGGTTCCGAACCCGGCAT
CGACGTCACCATCCGGGATTTCGGTCCCGGCATTCCCGAGGAGCACATTCCGCGCATCACTGAGCGCTTCTATCGCATCG
ACGTCGAGACCAGCCGGACCCAGAAAGGCACTGGCCTTGGCCTGTCCATCGTCAAGCACATCCTGACGCGCCACAATGCC
AGGCTGACGATCAAATCCGAGGTCGGCAAGGGCGCCGCCTTCTCGGTTCATTTGCCGACGCACTGA

Upstream 100 bases:

>100_bases
TTTCAGCTTGCGGACTCATGCTATTGGGAGCCTCCATGCCGGTCTAGCAGGAAGTTGCCATGCGGCCGGACAGCGCCCGA
GAGGGCTATAGGACGCGCGG

Downstream 100 bases:

>100_bases
TACTGCCCTAGTTTTCCTTGGAACCGTTTCTTTTTTCTGTCATCCGGCTAGCGTATCAGCGGGGATTCGAGGAAACGACT
CAAGATCAAGAACCCGTGGG

Product: phosphate regulon, two-component sensor histidine kinase, phoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 420

Protein sequence:

>421_residues
MAEQSAEQASVAQAMAIRLWNSRWLLVAGVIGILIAFAFAGISAYVLVPALLLLLAAALLPTTGLRQSGENAAAIEAIGL
QRLSGEYLAAAVADPLIIFDRSATIVHANAAAFAAFGGIAPGLSLPLKFRAPEMQTLLDSVLSGTIASDVVDYTEKLPVE
RAYRVSASSVGHGTDLYVLVFKDQSETRRIDRMRADFIANASHELRTPLASIAGFIETLRGPARNDPAAREQFLQIMQNQ
TGRMARLIDDLLSLSRLEMKPYLKPGTEVDLRQTVDSVIDSLAPLAHENSVVIERDFAKGPLNVPGDRDELFQVFENLLE
NACKYGQSGGRVVVSIAHADDGSEPGIDVTIRDFGPGIPEEHIPRITERFYRIDVETSRTQKGTGLGLSIVKHILTRHNA
RLTIKSEVGKGAAFSVHLPTH

Sequences:

>Translated_421_residues
MAEQSAEQASVAQAMAIRLWNSRWLLVAGVIGILIAFAFAGISAYVLVPALLLLLAAALLPTTGLRQSGENAAAIEAIGL
QRLSGEYLAAAVADPLIIFDRSATIVHANAAAFAAFGGIAPGLSLPLKFRAPEMQTLLDSVLSGTIASDVVDYTEKLPVE
RAYRVSASSVGHGTDLYVLVFKDQSETRRIDRMRADFIANASHELRTPLASIAGFIETLRGPARNDPAAREQFLQIMQNQ
TGRMARLIDDLLSLSRLEMKPYLKPGTEVDLRQTVDSVIDSLAPLAHENSVVIERDFAKGPLNVPGDRDELFQVFENLLE
NACKYGQSGGRVVVSIAHADDGSEPGIDVTIRDFGPGIPEEHIPRITERFYRIDVETSRTQKGTGLGLSIVKHILTRHNA
RLTIKSEVGKGAAFSVHLPTH
>Mature_420_residues
AEQSAEQASVAQAMAIRLWNSRWLLVAGVIGILIAFAFAGISAYVLVPALLLLLAAALLPTTGLRQSGENAAAIEAIGLQ
RLSGEYLAAAVADPLIIFDRSATIVHANAAAFAAFGGIAPGLSLPLKFRAPEMQTLLDSVLSGTIASDVVDYTEKLPVER
AYRVSASSVGHGTDLYVLVFKDQSETRRIDRMRADFIANASHELRTPLASIAGFIETLRGPARNDPAAREQFLQIMQNQT
GRMARLIDDLLSLSRLEMKPYLKPGTEVDLRQTVDSVIDSLAPLAHENSVVIERDFAKGPLNVPGDRDELFQVFENLLEN
ACKYGQSGGRVVVSIAHADDGSEPGIDVTIRDFGPGIPEEHIPRITERFYRIDVETSRTQKGTGLGLSIVKHILTRHNAR
LTIKSEVGKGAAFSVHLPTH

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=37.1900826446281, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=31.8777292576419, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=31.140350877193, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=28.8793103448276, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=29.2035398230088, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788713, Length=264, Percent_Identity=28.7878787878788, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=28.3950617283951, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=29.7777777777778, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1789403, Length=202, Percent_Identity=32.6732673267327, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=26.1410788381743, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788549, Length=379, Percent_Identity=25.065963060686, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790861, Length=226, Percent_Identity=29.2035398230088, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=235, Percent_Identity=30.6382978723404, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87082128, Length=237, Percent_Identity=29.1139240506329, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=28.2051282051282, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790551, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788279, Length=225, Percent_Identity=24.8888888888889, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45519; Mature: 45388

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQSAEQASVAQAMAIRLWNSRWLLVAGVIGILIAFAFAGISAYVLVPALLLLLAAALL
CCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTTGLRQSGENAAAIEAIGLQRLSGEYLAAAVADPLIIFDRSATIVHANAAAFAAFGGIA
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCEEEEECHHHHHHHCCCC
PGLSLPLKFRAPEMQTLLDSVLSGTIASDVVDYTEKLPVERAYRVSASSVGHGTDLYVLV
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEE
FKDQSETRRIDRMRADFIANASHELRTPLASIAGFIETLRGPARNDPAAREQFLQIMQNQ
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
TGRMARLIDDLLSLSRLEMKPYLKPGTEVDLRQTVDSVIDSLAPLAHENSVVIERDFAKG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
PLNVPGDRDELFQVFENLLENACKYGQSGGRVVVSIAHADDGSEPGIDVTIRDFGPGIPE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCH
EHIPRITERFYRIDVETSRTQKGTGLGLSIVKHILTRHNARLTIKSEVGKGAAFSVHLPT
HHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCC
H
C
>Mature Secondary Structure 
AEQSAEQASVAQAMAIRLWNSRWLLVAGVIGILIAFAFAGISAYVLVPALLLLLAAALL
CCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PTTGLRQSGENAAAIEAIGLQRLSGEYLAAAVADPLIIFDRSATIVHANAAAFAAFGGIA
CCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCEEEEECCCEEEEECHHHHHHHCCCC
PGLSLPLKFRAPEMQTLLDSVLSGTIASDVVDYTEKLPVERAYRVSASSVGHGTDLYVLV
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCEEEEEE
FKDQSETRRIDRMRADFIANASHELRTPLASIAGFIETLRGPARNDPAAREQFLQIMQNQ
ECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCC
TGRMARLIDDLLSLSRLEMKPYLKPGTEVDLRQTVDSVIDSLAPLAHENSVVIERDFAKG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
PLNVPGDRDELFQVFENLLENACKYGQSGGRVVVSIAHADDGSEPGIDVTIRDFGPGIPE
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCEEEEECCCCCCCH
EHIPRITERFYRIDVETSRTQKGTGLGLSIVKHILTRHNARLTIKSEVGKGAAFSVHLPT
HHHHHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCC
H
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]