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The map label for this gene is yafC [H]

Identifier: 13474620

GI number: 13474620

Start: 4447933

End: 4448877

Strand: Direct

Name: yafC [H]

Synonym: mlr5541

Alternate gene names: 13474620

Gene position: 4447933-4448877 (Clockwise)

Preceding gene: 13474618

Following gene: 13474621

Centisome position: 63.22

GC content: 63.17

Gene sequence:

>945_bases
ATGGACCTCTTTCGCTCCATGCAGGTTTTCGTGGCCACCGTTCAGGCAGGTTCGATGAGCTCCGCTGCTGCCCAAGTGGG
GCTCTCTCCGGCCATGGTCGGGCAGCATGTCGCGGCTTTGGAAGAGCGGCTGGGTACACGCCTTCTGAACCGGACCACAC
GCCGTCAGAGCCTGACTGATTTTGGGGCAAGTTACATCGAGCAATGCCGGGACATCCTCGACCGCGTGGCCATCGCGGAT
CGGGAGGCCGAGGCGCTGCAAACGGGAGCACGCGGGCAGTTGCGGGTCACGGCGCCGACGACATTCGGGGCGGAAGTTCT
GGTTCCCGCGCTGCGGCGCTATCGCGAGCTTGCCCCCGAAGTGACGCTCGACATCACGCTGACGGACAGAAACGTCGATC
TCGTGGAGGAAGGCTTCGACATAGCGTTCCGCATCGGCACGCTTCCCGACAATCACCTGATTGCGCGCAGCCTTGCTCCC
TACCGGATGATGATCTGTGCCGCGCCGGATTATCTGGTGCGCAAAGGCATGCCAGAACACCCTAGCGAGCTTTCTAGCCA
CGAAGTCGTCGGCTTCACTCCAGCAGCGCGGTCGCCCTGGAGGATGTCGAAAGGTGGCGACGTAGTGGAGGTGGAGCCCG
CTTGGACGGTTACGGTCAACAGCGGCCAGGCGGTGCGGACGGCCGCCCGCGCGGGTTTGGGTGTAGTCATGCAACCAGCC
ATCCTTCTCAGCCCTGATGTGCAGGCCGGGCAGCTCGTCCAGCTTTTTCCCGATTGGCATCTGCGCGAACGACCCATGTC
GCTCCTCTACCATCGCGATCGACGCATGACGCCGCGCCTGCGCAGCTTCATCTCTTTCGCAGCGGCGGAATTTGGGGTCG
TCGCAGAGGATCAAGCCTCCGAGGTCGGCGAAACCTCCGGATTGGTGCGCGACTTCGACGTATAG

Upstream 100 bases:

>100_bases
GCCGTGCTCCTGAGTGGGTTTGGTCACGGGCGTTGTAATTGGAAGGCATGTGGCTGATAATTGTCAAAATTATTGGATCA
TTTGAAAGCGTTGGTATTGA

Downstream 100 bases:

>100_bases
ATGAGGCTTGCATCGATGGCGCGGGCAAGCTTGTCGTAGTGGCTCTGCCCTGGTGCTGAAAATCTCGCAACGGGTTCCGA
GCCGAAACTCGGGCCGGGCG

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MDLFRSMQVFVATVQAGSMSSAAAQVGLSPAMVGQHVAALEERLGTRLLNRTTRRQSLTDFGASYIEQCRDILDRVAIAD
REAEALQTGARGQLRVTAPTTFGAEVLVPALRRYRELAPEVTLDITLTDRNVDLVEEGFDIAFRIGTLPDNHLIARSLAP
YRMMICAAPDYLVRKGMPEHPSELSSHEVVGFTPAARSPWRMSKGGDVVEVEPAWTVTVNSGQAVRTAARAGLGVVMQPA
ILLSPDVQAGQLVQLFPDWHLRERPMSLLYHRDRRMTPRLRSFISFAAAEFGVVAEDQASEVGETSGLVRDFDV

Sequences:

>Translated_314_residues
MDLFRSMQVFVATVQAGSMSSAAAQVGLSPAMVGQHVAALEERLGTRLLNRTTRRQSLTDFGASYIEQCRDILDRVAIAD
REAEALQTGARGQLRVTAPTTFGAEVLVPALRRYRELAPEVTLDITLTDRNVDLVEEGFDIAFRIGTLPDNHLIARSLAP
YRMMICAAPDYLVRKGMPEHPSELSSHEVVGFTPAARSPWRMSKGGDVVEVEPAWTVTVNSGQAVRTAARAGLGVVMQPA
ILLSPDVQAGQLVQLFPDWHLRERPMSLLYHRDRRMTPRLRSFISFAAAEFGVVAEDQASEVGETSGLVRDFDV
>Mature_314_residues
MDLFRSMQVFVATVQAGSMSSAAAQVGLSPAMVGQHVAALEERLGTRLLNRTTRRQSLTDFGASYIEQCRDILDRVAIAD
REAEALQTGARGQLRVTAPTTFGAEVLVPALRRYRELAPEVTLDITLTDRNVDLVEEGFDIAFRIGTLPDNHLIARSLAP
YRMMICAAPDYLVRKGMPEHPSELSSHEVVGFTPAARSPWRMSKGGDVVEVEPAWTVTVNSGQAVRTAARAGLGVVMQPA
ILLSPDVQAGQLVQLFPDWHLRERPMSLLYHRDRRMTPRLRSFISFAAAEFGVVAEDQASEVGETSGLVRDFDV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=283, Percent_Identity=36.3957597173145, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=33.7792642140468, Blast_Score=174, Evalue=6e-45,
Organism=Escherichia coli, GI1789440, Length=289, Percent_Identity=29.4117647058824, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI1789639, Length=286, Percent_Identity=27.6223776223776, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=27.3037542662116, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87081978, Length=264, Percent_Identity=29.9242424242424, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787589, Length=273, Percent_Identity=28.2051282051282, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1790011, Length=268, Percent_Identity=23.134328358209, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789173, Length=296, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=298, Percent_Identity=21.4765100671141, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788706, Length=289, Percent_Identity=23.1833910034602, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34488; Mature: 34488

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLFRSMQVFVATVQAGSMSSAAAQVGLSPAMVGQHVAALEERLGTRLLNRTTRRQSLTD
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGASYIEQCRDILDRVAIADREAEALQTGARGQLRVTAPTTFGAEVLVPALRRYRELAPE
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
VTLDITLTDRNVDLVEEGFDIAFRIGTLPDNHLIARSLAPYRMMICAAPDYLVRKGMPEH
EEEEEEEECCCCHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEEECCCHHHHHCCCCCC
PSELSSHEVVGFTPAARSPWRMSKGGDVVEVEPAWTVTVNSGQAVRTAARAGLGVVMQPA
CHHCCCCCEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHCCCCEEECCC
ILLSPDVQAGQLVQLFPDWHLRERPMSLLYHRDRRMTPRLRSFISFAAAEFGVVAEDQAS
EEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCHHH
EVGETSGLVRDFDV
HHHHHCCCEECCCC
>Mature Secondary Structure
MDLFRSMQVFVATVQAGSMSSAAAQVGLSPAMVGQHVAALEERLGTRLLNRTTRRQSLTD
CCHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGASYIEQCRDILDRVAIADREAEALQTGARGQLRVTAPTTFGAEVLVPALRRYRELAPE
HHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
VTLDITLTDRNVDLVEEGFDIAFRIGTLPDNHLIARSLAPYRMMICAAPDYLVRKGMPEH
EEEEEEEECCCCHHHHCCCEEEEEECCCCCCCHHHHHCCCCEEEEECCCHHHHHCCCCCC
PSELSSHEVVGFTPAARSPWRMSKGGDVVEVEPAWTVTVNSGQAVRTAARAGLGVVMQPA
CHHCCCCCEEEECCCCCCCCCCCCCCCEEEECCEEEEEECCCCHHHHHHHCCCCEEECCC
ILLSPDVQAGQLVQLFPDWHLRERPMSLLYHRDRRMTPRLRSFISFAAAEFGVVAEDQAS
EEECCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEECCHHH
EVGETSGLVRDFDV
HHHHHCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]