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The map label for this gene is lnt

Identifier: 13474621

GI number: 13474621

Start: 4449058

End: 4450650

Strand: Direct

Name: lnt

Synonym: mlr5543

Alternate gene names: 13474621

Gene position: 4449058-4450650 (Clockwise)

Preceding gene: 13474620

Following gene: 13474622

Centisome position: 63.23

GC content: 63.28

Gene sequence:

>1593_bases
ATGGAGCGCCTGGCCGGCCGGATAATTCTGCTTTGGGGTTGGCGGCGTGCGCTCGTGGCCTTTCTTGCCGGGGCGCTGGC
GGTGCTTGGCCAGGCGCCTTACGATTTCTTCGCCGCCTGCTTCATCTCGTTTCCGCTGCTGGTCTGGCTGCTCGATGGCG
CGACCGGCGAAGCTTCCGGCAGCCTTTTCAGACGCTTGCTGCCGGCCTTCGCCGTCGGCTGGTGGTTCGGCTTCGGCTAT
TTCCTCGCCGGTCTCTGGTGGATCGGCTCGGCGCTGCTGGTCGAGGCCGATGAGTTTGCCTGGGCACTTCCCTTCGCCGT
GGTCGGCATTCCCTTCGCGCTGGCCTTTTTCTACGGCTTCGCGACGCTGGTCGCCCGGCTTCTGTGGAGCAGTGATATCG
GCCGCATCGCCGCCCTTGCCTTCGGCTTCGGGCTGACAGAGTGGCTGCGCGGCTTCCTGTTCACTGGTTTTCCCTGGAAT
GCCATTGGCTACGCGGCAATGCCCGTGCCTCTCCTCATGCAGAGCGTTTCGGTGACCGGCATGATCGGCATGAACGTGCT
TGCCGTGTTCCTCTTTTCATTGCCGGCGCTGCTGGTGGCGCGCCGGCATCTTCGCCTGGGCGCGGCACTGTTCGTGCTGC
TTGCATCAGCCCATGTCGGTTTCGGCTACATCAGGCTTGCCGCTCCTGAAAAACCGGCCGAGCGCAGCCTGGATGTCCGC
ATTGTCCAACCGGCCGTCGACCTGTCGGAAAAATGGGATGCCTCGGTGCGCGACCGCATCTTCGCCACCTTGCTCGGCCT
GTCCGCCAAGGCGCCGGACCCCGGTCACGGCAAGCCACAACTCATTCTCTGGCCGGAAACCTCGGTGCCTTTCCTCTTCA
CCGAACGGCCTGACGCGCTGACGGCGCTGGGCGACATGCTGGCCGATGGCCAGATGCTGATTGCCGGGGTCGTTCGCGAG
GAAGGGGGCTCGGCGGCCAGCACAGACAGCCGCTATTACAATTCCGTGGTGGCGATCAACGACAGGGGCGAAATCACTGA
CGCCGTCGACAAGGTCCATCTGGTGCCGTTCGGCGAGTACCTGCCTTTCGGCGACCTGCTCAACCGTTTCGGCATCGCGC
AGCTTGTCGCCGGACCGGTGACGTTCGCCGCCGGCAACGAGCGCCACGCCATCTCACTGCCGGGCGGCATCCGTGCCCTG
CCTTTTATCTGTTACGAGGTGATCTTTCCCGATCTTGTGGCAGTTGACGCTACGTCAGCGCAGCTTATTGTGAACGTTAC
CAATGATGCCTGGTTCGGGGACACACCGGGACCGTATCAGCATTTCAGGCAGGCCCAGATTCGCGCGGTGGAGAACGGAT
TGCCCTTGCTGCGTGCTGCCAACAACGGCATCTCGGCCGTCGTCGATCCGCGCGGACGCATCGTCGATGCGCTGGCGATC
GACGCGCGCGGAGCCATCGATGTGAAGGTGCCGATTTCTGGACAGGCGGTCGTTTCCTCGGCCCAGCGGCGCATTAACGG
AATGCTGATCATGTTGCTGTTTGCGCTGGTGGGGGCACTGTTGAACGTAAGGCAAAGGCTACGGGTGAATTGA

Upstream 100 bases:

>100_bases
GCCGAAACTCGGGCCGGGCGGAGCCGGGTCGGTCCCGTTTGGAGCGCGGGCCGCGGCCTGATAAATCTTGCGTCCTGATT
CGCGCGACTCGGAAGTATGC

Downstream 100 bases:

>100_bases
CAGTCGACACATTAGAAACTCATACTGTATCGCCTGAAAATTTCTCGAAGCCGGTGGATCGTCTGTTGGGGCAGTCGCCT
CCGGCTTTTTTTGGGCAGGA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MERLAGRIILLWGWRRALVAFLAGALAVLGQAPYDFFAACFISFPLLVWLLDGATGEASGSLFRRLLPAFAVGWWFGFGY
FLAGLWWIGSALLVEADEFAWALPFAVVGIPFALAFFYGFATLVARLLWSSDIGRIAALAFGFGLTEWLRGFLFTGFPWN
AIGYAAMPVPLLMQSVSVTGMIGMNVLAVFLFSLPALLVARRHLRLGAALFVLLASAHVGFGYIRLAAPEKPAERSLDVR
IVQPAVDLSEKWDASVRDRIFATLLGLSAKAPDPGHGKPQLILWPETSVPFLFTERPDALTALGDMLADGQMLIAGVVRE
EGGSAASTDSRYYNSVVAINDRGEITDAVDKVHLVPFGEYLPFGDLLNRFGIAQLVAGPVTFAAGNERHAISLPGGIRAL
PFICYEVIFPDLVAVDATSAQLIVNVTNDAWFGDTPGPYQHFRQAQIRAVENGLPLLRAANNGISAVVDPRGRIVDALAI
DARGAIDVKVPISGQAVVSSAQRRINGMLIMLLFALVGALLNVRQRLRVN

Sequences:

>Translated_530_residues
MERLAGRIILLWGWRRALVAFLAGALAVLGQAPYDFFAACFISFPLLVWLLDGATGEASGSLFRRLLPAFAVGWWFGFGY
FLAGLWWIGSALLVEADEFAWALPFAVVGIPFALAFFYGFATLVARLLWSSDIGRIAALAFGFGLTEWLRGFLFTGFPWN
AIGYAAMPVPLLMQSVSVTGMIGMNVLAVFLFSLPALLVARRHLRLGAALFVLLASAHVGFGYIRLAAPEKPAERSLDVR
IVQPAVDLSEKWDASVRDRIFATLLGLSAKAPDPGHGKPQLILWPETSVPFLFTERPDALTALGDMLADGQMLIAGVVRE
EGGSAASTDSRYYNSVVAINDRGEITDAVDKVHLVPFGEYLPFGDLLNRFGIAQLVAGPVTFAAGNERHAISLPGGIRAL
PFICYEVIFPDLVAVDATSAQLIVNVTNDAWFGDTPGPYQHFRQAQIRAVENGLPLLRAANNGISAVVDPRGRIVDALAI
DARGAIDVKVPISGQAVVSSAQRRINGMLIMLLFALVGALLNVRQRLRVN
>Mature_530_residues
MERLAGRIILLWGWRRALVAFLAGALAVLGQAPYDFFAACFISFPLLVWLLDGATGEASGSLFRRLLPAFAVGWWFGFGY
FLAGLWWIGSALLVEADEFAWALPFAVVGIPFALAFFYGFATLVARLLWSSDIGRIAALAFGFGLTEWLRGFLFTGFPWN
AIGYAAMPVPLLMQSVSVTGMIGMNVLAVFLFSLPALLVARRHLRLGAALFVLLASAHVGFGYIRLAAPEKPAERSLDVR
IVQPAVDLSEKWDASVRDRIFATLLGLSAKAPDPGHGKPQLILWPETSVPFLFTERPDALTALGDMLADGQMLIAGVVRE
EGGSAASTDSRYYNSVVAINDRGEITDAVDKVHLVPFGEYLPFGDLLNRFGIAQLVAGPVTFAAGNERHAISLPGGIRAL
PFICYEVIFPDLVAVDATSAQLIVNVTNDAWFGDTPGPYQHFRQAQIRAVENGLPLLRAANNGISAVVDPRGRIVDALAI
DARGAIDVKVPISGQAVVSSAQRRINGMLIMLLFALVGALLNVRQRLRVN

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=525, Percent_Identity=30.8571428571429, Blast_Score=186, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_RHILO (Q98BJ6)

Other databases:

- EMBL:   BA000012
- RefSeq:   NP_106190.1
- ProteinModelPortal:   Q98BJ6
- GeneID:   1228851
- GenomeReviews:   BA000012_GR
- KEGG:   mlo:mlr5543
- NMPDR:   fig|266835.1.peg.4294
- HOGENOM:   HBG616234
- ProtClustDB:   PRK00302
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57279; Mature: 57279

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1438a328)-; HASH(0x14da97d0)-; HASH(0x151cd9c4)-; HASH(0x150d0ed8)-; HASH(0x106bfa34)-; HASH(0x11845d80)-; HASH(0x133e29c4)-; HASH(0x10721e68)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERLAGRIILLWGWRRALVAFLAGALAVLGQAPYDFFAACFISFPLLVWLLDGATGEASG
CCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
SLFRRLLPAFAVGWWFGFGYFLAGLWWIGSALLVEADEFAWALPFAVVGIPFALAFFYGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHH
ATLVARLLWSSDIGRIAALAFGFGLTEWLRGFLFTGFPWNAIGYAAMPVPLLMQSVSVTG
HHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHCCHHHCCHHHHHHHHHHHH
MIGMNVLAVFLFSLPALLVARRHLRLGAALFVLLASAHVGFGYIRLAAPEKPAERSLDVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
IVQPAVDLSEKWDASVRDRIFATLLGLSAKAPDPGHGKPQLILWPETSVPFLFTERPDAL
EECCHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEECCCHHH
TALGDMLADGQMLIAGVVREEGGSAASTDSRYYNSVVAINDRGEITDAVDKVHLVPFGEY
HHHHHHHCCCCEEEHHHHHHCCCCCCCCCHHHHCCEEEECCCCCHHHHHHCEEEEECCCC
LPFGDLLNRFGIAQLVAGPVTFAAGNERHAISLPGGIRALPFICYEVIFPDLVAVDATSA
CCHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHEEECCCCC
QLIVNVTNDAWFGDTPGPYQHFRQAQIRAVENGLPLLRAANNGISAVVDPRGRIVDALAI
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCEEEEEEE
DARGAIDVKVPISGQAVVSSAQRRINGMLIMLLFALVGALLNVRQRLRVN
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MERLAGRIILLWGWRRALVAFLAGALAVLGQAPYDFFAACFISFPLLVWLLDGATGEASG
CCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHH
SLFRRLLPAFAVGWWFGFGYFLAGLWWIGSALLVEADEFAWALPFAVVGIPFALAFFYGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEECHHHHHHHHHHHHHHHHHHHHHHHH
ATLVARLLWSSDIGRIAALAFGFGLTEWLRGFLFTGFPWNAIGYAAMPVPLLMQSVSVTG
HHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCHHCCHHHCCHHHHHHHHHHHH
MIGMNVLAVFLFSLPALLVARRHLRLGAALFVLLASAHVGFGYIRLAAPEKPAERSLDVR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCEE
IVQPAVDLSEKWDASVRDRIFATLLGLSAKAPDPGHGKPQLILWPETSVPFLFTERPDAL
EECCHHCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCEEEECCCHHH
TALGDMLADGQMLIAGVVREEGGSAASTDSRYYNSVVAINDRGEITDAVDKVHLVPFGEY
HHHHHHHCCCCEEEHHHHHHCCCCCCCCCHHHHCCEEEECCCCCHHHHHHCEEEEECCCC
LPFGDLLNRFGIAQLVAGPVTFAAGNERHAISLPGGIRALPFICYEVIFPDLVAVDATSA
CCHHHHHHHHHHHHHHHCCEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHEEECCCCC
QLIVNVTNDAWFGDTPGPYQHFRQAQIRAVENGLPLLRAANNGISAVVDPRGRIVDALAI
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCEEEEEEE
DARGAIDVKVPISGQAVVSSAQRRINGMLIMLLFALVGALLNVRQRLRVN
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11214968